Data-driven normalization strategies for high-throughput quantitative RT-PCR (2009)
Mar Jessica, Kimura Yasumasa, Schroder Kate, Irvine Katharine, Hayashizaki Yoshihide, Suzuki Harukazu, ...
Abstract Background High-throughput real-time quantitative reverse transcriptase polymerase chain reaction (qPCR) is a widely used technique in experiments where expression patterns of genes are to...
Expression analysis of G Protein-Coupled Receptors in mouse macrophages (2008)
Lattin Jane, Schroder Kate, Su Andrew, Walker John, Zhang Jie, Wiltshire Tim, ...
Abstract Background Monocytes and macrophages express an extensive repertoire of G Protein-Coupled Receptors (GPCRs) that regulate inflammation and immunity. In this study we performed a systematic...
Hadler Kieran, Huber Thomas, Cassady A Ian, Weber Jane, Robinson Jodie, Burrows Allan, ...
Abstract Background Tartrate-resistant acid phosphatases (TRAcPs), also known as purple acid phosphatases (PAPs), are a family of binuclear metallohydrolases that have been identified in plants,...
Computational promoter analysis of mouse, rat and human antimicrobial peptide-coding genes (2006)
Brahmachary Manisha, Schönbach Christian, Yang Liang, Huang Enli, Tan Sin, Chowdhary Rajesh, ...
Abstract Background Mammalian antimicrobial peptides (AMPs) are effectors of the innate immune response. A multitude of signals coming from pathways of mammalian pathogen/pattern recognition...
Genetic control of the innate immune response (2003)
Wells Christine, Ravasi Timothy, Faulkner Geoffrey, Carninci Piero, Okazaki Yasushi, Hayashizaki Yoshihide, ...
Abstract Background Susceptibility to infectious diseases is directed, in part, by the interaction between the invading pathogen and host macrophages. This study examines the influence of genetic...
Hume David, Underhill David, Sweet Matthew, Ozinsky Adrian, Liew Foo, Aderem Alan
Abstract Background Macrophages sense microorganisms through activation of members of the Toll-like receptor family, which initiate signals linked to transcription of many inflammation associated...