Relationship of cytokines and cytokine signaling to immunodeficiency disorders in the mouse (1998)
Morawetz,R.A., Giese,N.A., Gabriele,L., Rothman,P., Horak,I., Ozato,K., ...
The contributions of cytokines to the development and progression of disease in a mouse model of retrovirus-induced immunodeficiency (MAIDS) are controversial. Some studies have indicated an...
Analysis of the determinants of neurotropism and neurotoxicity of HFV in transgenic mice. (1996)
Tschopp, R R, Brandner, S, Marino, S, Bothe, K, Horak, I, Rethwilm, A, ...
The Bel-1 protein of human foamy virus (HFV) is a transactivator acting on the U3 region of the long terminal repeat and on an internal promoter (IP) immediately upstream of the bel genes. An HFV...
Thesis (D.V.S.)--University of Pretoria, 1966.
Funke, B, Zuleger, B, Benavente, R, Schuster, T, Goller, M, Stévenin, J, ...
The murine poly(C)-binding protein (mCBP) was previously shown to belong to the group of K-homology (KH) proteins by virtue of its homology to hnRNP-K. We have isolated cDNA-splice variants of mCBP...
Resistance of cultures of normal T cells to infection with murine type C viruses.
Horak, I, Enjuanes, L, Lee, J C, Ihle, J N
Long-term continuous cultures of normal T cells were established from C57BL/6 and BALB/c mice by using conditioned medium from concanavalin A-stimulated lymphocytes. The ability of various murine...
Antiviral immune responses in mice deficient for both interleukin-2 and interleukin-4.
Bachmann, M F, Schorle, H, Kühn, R, Müller, W, Hengartner, H, Zinkernagel, R M, ...
Antiviral immune responses of mice lacking interleukin-2 (IL-2) or IL-4 or both IL-2 and IL-4 (IL-2/4) were compared by using different viruses. Primary cytotoxic T-lymphocyte (CTL) responses against...
Synthetic oligonucleotides complementary to putative retroviral primer-binding sites were used as hybridization probes to detect novel retroviruslike sequences. An 8.1-kilobase element with...
Murine protein which binds preferentially to oligo-C-rich single-stranded nucleic acids.
Goller, M, Funke, B, Gehe-Becker, C, Kröger, B, Lottspeich, F, Horak, I
Two single-stranded nucleic acid binding proteins mCBP and mCTBP were identified by means of their binding to a potential recombination hotspot in LTRs of mouse retro-transposons. Both are nuclear...
Evidence for mobility of a new family of mouse middle repetitive DNA elements (LTR-IS).
Wirth, T, Schmidt, M, Baumruker, T, Horak, I
Locus variation and sequence conservation of mouse LTR-IS elements, a new family of middle repetitive DNA sequences was studied. It is shown that LTR-IS sequences are present in all the inbred...
Baumruker, T, Gehe, C, Horak, I
A site of genomic insertion of the mouse retrotransposon LTR-IS/MuRRS was analysed. The comparison of the genomic and the cDNA clones indicates the insertion of the LTR-IS element into the 3'...
Köhrer, K, Grummt, I, Horak, I
LTR-IS elements are middle repetitive sequences in the mouse genome with structural features of solitary retroviral LTRs. In order to get some insight in the possible functional role of these...
Schmidt, M, Wirth, T, Kröger, B, Horak, I
A new class of murine retrovirus-related sequences (MuRRS) is described. These 5.7 kb long transposon-like DNA-elements start and end with approximately 600 bp long repeats identical to previously...
Klenner, D, Horak, I, Schimpl, A, Wecker, E
Concanavalin A-stimulated murine spleen cells and antigen-stimulated B lymphocytes of normal mice express an antigen that reacts with goat antiserum against glycoprotein (gp) 70. Structural analysis...
Horak, I, Lee, J C, Enjuanes, L, Ihle, J N
Moloney leukemia virus (MoLV) induces lymphomas in BALB/c mice which either involve an immature thymic T-cell subpopulation or a splenic mature T-cell subpopulation. To investigate further the...
Schmidt, M, Glöggler, K, Wirth, T, Horak, I
Two endogenous retroviral long terminal repeats (LTRs) were sequenced and compared to LTR-IS (a family of insertion-element-like sequences with structural features of solitary retroviral LTRs) and to...
Wirth, T, Glöggler, K, Baumruker, T, Schmidt, M, Horak, I
Screening of a 129/J mouse genomic library under nonstringent hybridization conditions with a xenotropic virus-like long terminal repeat (LTR) probe revealed a family of sequences resembling...
Funke, B, Zuleger, B, Benavente, R, Schuster, T, Goller, M, Stévenin, J, ...
The murine poly(C)-binding protein (mCBP) was previously shown to belong to the group of K-homology (KH) proteins by virtue of its homology to hnRNP-K. We have isolated cDNA-splice variants of mCBP...
Resistance of cultures of normal T cells to infection with murine type C viruses.
Horak, I, Enjuanes, L, Lee, J C, Ihle, J N
Long-term continuous cultures of normal T cells were established from C57BL/6 and BALB/c mice by using conditioned medium from concanavalin A-stimulated lymphocytes. The ability of various murine...
Antiviral immune responses in mice deficient for both interleukin-2 and interleukin-4.
Bachmann, M F, Schorle, H, Kühn, R, Müller, W, Hengartner, H, Zinkernagel, R M, ...
Antiviral immune responses of mice lacking interleukin-2 (IL-2) or IL-4 or both IL-2 and IL-4 (IL-2/4) were compared by using different viruses. Primary cytotoxic T-lymphocyte (CTL) responses against...
Synthetic oligonucleotides complementary to putative retroviral primer-binding sites were used as hybridization probes to detect novel retroviruslike sequences. An 8.1-kilobase element with...
Murine protein which binds preferentially to oligo-C-rich single-stranded nucleic acids.
Goller, M, Funke, B, Gehe-Becker, C, Kröger, B, Lottspeich, F, Horak, I
Two single-stranded nucleic acid binding proteins mCBP and mCTBP were identified by means of their binding to a potential recombination hotspot in LTRs of mouse retro-transposons. Both are nuclear...
Evidence for mobility of a new family of mouse middle repetitive DNA elements (LTR-IS).
Wirth, T, Schmidt, M, Baumruker, T, Horak, I
Locus variation and sequence conservation of mouse LTR-IS elements, a new family of middle repetitive DNA sequences was studied. It is shown that LTR-IS sequences are present in all the inbred...
Baumruker, T, Gehe, C, Horak, I
A site of genomic insertion of the mouse retrotransposon LTR-IS/MuRRS was analysed. The comparison of the genomic and the cDNA clones indicates the insertion of the LTR-IS element into the 3'...
Köhrer, K, Grummt, I, Horak, I
LTR-IS elements are middle repetitive sequences in the mouse genome with structural features of solitary retroviral LTRs. In order to get some insight in the possible functional role of these...
Schmidt, M, Wirth, T, Kröger, B, Horak, I
A new class of murine retrovirus-related sequences (MuRRS) is described. These 5.7 kb long transposon-like DNA-elements start and end with approximately 600 bp long repeats identical to previously...
Klenner, D, Horak, I, Schimpl, A, Wecker, E
Concanavalin A-stimulated murine spleen cells and antigen-stimulated B lymphocytes of normal mice express an antigen that reacts with goat antiserum against glycoprotein (gp) 70. Structural analysis...
Horak, I, Lee, J C, Enjuanes, L, Ihle, J N
Moloney leukemia virus (MoLV) induces lymphomas in BALB/c mice which either involve an immature thymic T-cell subpopulation or a splenic mature T-cell subpopulation. To investigate further the...
Schmidt, M, Glöggler, K, Wirth, T, Horak, I
Two endogenous retroviral long terminal repeats (LTRs) were sequenced and compared to LTR-IS (a family of insertion-element-like sequences with structural features of solitary retroviral LTRs) and to...
Wirth, T, Glöggler, K, Baumruker, T, Schmidt, M, Horak, I
Screening of a 129/J mouse genomic library under nonstringent hybridization conditions with a xenotropic virus-like long terminal repeat (LTR) probe revealed a family of sequences resembling...
Autenrieth, I, Bucheler, N, Bohn, E, Heinze, G, Horak, I
a Max v. Pettenkofer Institut für Hygiene und Medizinische Mikrobiologie, Ludwig Maximilians Universität, Pettenkoferstrasse 9a, D-80336 München, Germany, b Institute for Virology and...