Brown, J A, Rogers, E M, Boss, J M
The class II transactivator CIITA is required for transcriptional activation of the major histocompatibility complex (MHC) class II genes. Aside from an N-terminal acidic transcriptional activation...
Major histocompatibility complex class II genes contain a common complex enhancer that allows for their coordinate regulation. The X box element of the enhancer cooperatively binds the multisubunit...
Jabrane-Ferrat, N, Fontes, J D, Boss, J M, Peterlin, B M
The S box (also known as at the H, W, or Z box) is the 5'-most element of the conserved upstream sequences in promoters of major histocompatibility complex class II genes. It is important for their...
Jones, P L, Ping, D, Boss, J M
Manganese superoxide dismutase (MnSOD), a tumor necrosis factor (TNF)-inducible reactive oxygen-scavenging enzyme, protects cells from TNF-mediated apoptosis. To understand how MnSOD is regulated,...
Class II major histocompatibility genes contain a conserved upstream sequence (CUS) that is important in the expression of these genes. This region has been divided into two major elements, the X box...
Dialynas, D P, Murre, C, Quertermous, T, Boss, J M, Leiden, J M, Seidman, J G, ...
Complementary DNA (cDNA) encoding a human T-cell gamma chain has been cloned and sequenced. At the junction of the variable and joining regions, there is an apparent deletion of two nucleotides in...
Hasegawa, S L, Doetsch, P W, Hamilton, K K, Martin, A M, Okenquist, S A, Lenz, J, ...
A number of eukaryotic DNA binding proteins have been isolated by screening phage expression libraries with DNA probes containing the binding site of the DNA-binding protein. This methodology was...
The class II genes of the human Major Histocompatibility Complex (MHC) encode three isotypes of alpha/beta heterodimeric proteins, HLA-DR, -DQ, and -DP, which are responsible for presenting processed...
Regulatory factor-X binding to mutant HLA-DRA promoter sequences.
Hasegawa, S L, Sloan, J H, Reith, W, Mach, B, Boss, J M
The class II genes of the major histocompatibility complex (MHC) encode a family of cell surface glycoproteins that present processed antigen to the T cell receptor. Class II genes are regulated...
Sequence analysis of the human major histocompatibility gene SX alpha.
Boss, J M, Mengler, R, Okada, K, Auffray, C, Strominger, J L
The DP subregion of the human major histocompatibility complex contains two closely linked gene pairs, DP alpha, DP beta and SX alpha, SX beta. The exon-intron organization and the complete DNA...
To investigate the cis-acting DNA elements that are involved in regulation of class II major histocompatibility complex genes, including gamma-interferon (gamma-IFN) induction, 5' flanking DNA...
Structural organization of the DR subregion of the human major histocompatibility complex.
Spies, T, Sorrentino, R, Boss, J M, Okada, K, Strominger, J L
Two clusters of overlapping cosmid and lambda phage clones comprising 205 kilobases (kb) have been isolated from the DR subregion of the human major histocompatibility complex from a DR4 haplotype. A...
Collins, T, Korman, A J, Wake, C T, Boss, J M, Kappes, D J, Fiers, W, ...
Immune interferon (IFN-gamma) increases the surface expression of HLA-A,B antigens and induces the surface expression of HLA-DR antigens on vascular endothelial cells and dermal fibroblasts. Here we...
Cloning and sequence analysis of the human major histocompatibility complex gene DC-3 beta.
The DC antigen is one of the class II major histocompatibility antigens involved in the regulation of the immune response. This molecule is a heterodimer composed of an alpha and a beta chain....
Gene organization of DC and DX subregions of the human major histocompatibility complex.
Okada, K, Boss, J M, Prentice, H, Spies, T, Mengler, R, Auffray, C, ...
The DC and DX subregions of the human major histocompatibility complex (MHC) have been cloned from a cosmid library made from a human B-cell line, Priess. The DC subregion, 48 kilobases, includes the...
Roux-Dosseto, M, Auffray, C, Lillie, J W, Boss, J M, Cohen, D, DeMars, R, ...
A class II antigen beta-chain cDNA clone was isolated from a human B-cell cDNA library by using as a probe the murine I-A beta gene. This cDNA clone, pHA beta, was shown to be distinct from the DC...
Okada, K, Prentice, H L, Boss, J M, Levy, D J, Kappes, D, Spies, T, ...
The SB region of the human major histocompatibility complex (MHC) has been cloned from cosmid and lambda phage libraries made from the human B-lymphoblastoid cell line Priess (DR4/4, DC4/4, SB3/4)....
Brown, J A, Rogers, E M, Boss, J M
The class II transactivator CIITA is required for transcriptional activation of the major histocompatibility complex (MHC) class II genes. Aside from an N-terminal acidic transcriptional activation...
Major histocompatibility complex class II genes contain a common complex enhancer that allows for their coordinate regulation. The X box element of the enhancer cooperatively binds the multisubunit...
Jabrane-Ferrat, N, Fontes, J D, Boss, J M, Peterlin, B M
The S box (also known as at the H, W, or Z box) is the 5'-most element of the conserved upstream sequences in promoters of major histocompatibility complex class II genes. It is important for their...
Jones, P L, Ping, D, Boss, J M
Manganese superoxide dismutase (MnSOD), a tumor necrosis factor (TNF)-inducible reactive oxygen-scavenging enzyme, protects cells from TNF-mediated apoptosis. To understand how MnSOD is regulated,...
Class II major histocompatibility genes contain a conserved upstream sequence (CUS) that is important in the expression of these genes. This region has been divided into two major elements, the X box...
Dialynas, D P, Murre, C, Quertermous, T, Boss, J M, Leiden, J M, Seidman, J G, ...
Complementary DNA (cDNA) encoding a human T-cell gamma chain has been cloned and sequenced. At the junction of the variable and joining regions, there is an apparent deletion of two nucleotides in...
Hasegawa, S L, Doetsch, P W, Hamilton, K K, Martin, A M, Okenquist, S A, Lenz, J, ...
A number of eukaryotic DNA binding proteins have been isolated by screening phage expression libraries with DNA probes containing the binding site of the DNA-binding protein. This methodology was...
The class II genes of the human Major Histocompatibility Complex (MHC) encode three isotypes of alpha/beta heterodimeric proteins, HLA-DR, -DQ, and -DP, which are responsible for presenting processed...
Regulatory factor-X binding to mutant HLA-DRA promoter sequences.
Hasegawa, S L, Sloan, J H, Reith, W, Mach, B, Boss, J M
The class II genes of the major histocompatibility complex (MHC) encode a family of cell surface glycoproteins that present processed antigen to the T cell receptor. Class II genes are regulated...
Sequence analysis of the human major histocompatibility gene SX alpha.
Boss, J M, Mengler, R, Okada, K, Auffray, C, Strominger, J L
The DP subregion of the human major histocompatibility complex contains two closely linked gene pairs, DP alpha, DP beta and SX alpha, SX beta. The exon-intron organization and the complete DNA...
To investigate the cis-acting DNA elements that are involved in regulation of class II major histocompatibility complex genes, including gamma-interferon (gamma-IFN) induction, 5' flanking DNA...
Structural organization of the DR subregion of the human major histocompatibility complex.
Spies, T, Sorrentino, R, Boss, J M, Okada, K, Strominger, J L
Two clusters of overlapping cosmid and lambda phage clones comprising 205 kilobases (kb) have been isolated from the DR subregion of the human major histocompatibility complex from a DR4 haplotype. A...
Collins, T, Korman, A J, Wake, C T, Boss, J M, Kappes, D J, Fiers, W, ...
Immune interferon (IFN-gamma) increases the surface expression of HLA-A,B antigens and induces the surface expression of HLA-DR antigens on vascular endothelial cells and dermal fibroblasts. Here we...
Cloning and sequence analysis of the human major histocompatibility complex gene DC-3 beta.
The DC antigen is one of the class II major histocompatibility antigens involved in the regulation of the immune response. This molecule is a heterodimer composed of an alpha and a beta chain....
Gene organization of DC and DX subregions of the human major histocompatibility complex.
Okada, K, Boss, J M, Prentice, H, Spies, T, Mengler, R, Auffray, C, ...
The DC and DX subregions of the human major histocompatibility complex (MHC) have been cloned from a cosmid library made from a human B-cell line, Priess. The DC subregion, 48 kilobases, includes the...
Roux-Dosseto, M, Auffray, C, Lillie, J W, Boss, J M, Cohen, D, DeMars, R, ...
A class II antigen beta-chain cDNA clone was isolated from a human B-cell cDNA library by using as a probe the murine I-A beta gene. This cDNA clone, pHA beta, was shown to be distinct from the DC...
Okada, K, Prentice, H L, Boss, J M, Levy, D J, Kappes, D, Spies, T, ...
The SB region of the human major histocompatibility complex (MHC) has been cloned from cosmid and lambda phage libraries made from the human B-lymphoblastoid cell line Priess (DR4/4, DC4/4, SB3/4)....
Boss, J M, Laster, S M, Gooding, L R
The ability of cells to resist the cytolytic actions of tumour necrosis factor (TNF) has been shown to require TNF-induced gene expression. It has been shown in some human cells that the gene...
Contraceptive pill-induced porphyria cutanea tarda presenting with onycholysis of the finger nails.
Byrne, J. P., Boss, J. M., Dawber, R. P.
A case of porphyria cutanea tarda induced by oral contraceptive pill therapy is reported, and its unusual presenting sign of onycholysis of the finger nails is noted. Reference is made to the rarity...