J. Rüschoff

The helix-loop-helix transcription factor SEF-2 regulates the activity of a novel initiator element in the promoter of the human somatostatin receptor II gene.

Pscherer, A, Dörflinger, U, Kirfel, J, Gawlas, K, Rüschoff, J, Buettner, R, ...

The effects of somatostatin hormones are mediated by a family of five different seven-helix transmembrane spanning receptors (SSTR1-5). The expression of the five different SSTR subtypes displays a...

The helix-loop-helix transcription factor SEF-2 regulates the activity of a novel initiator element in the promoter of the human somatostatin receptor II gene.

Pscherer, A, Dörflinger, U, Kirfel, J, Gawlas, K, Rüschoff, J, Buettner, R, ...

The effects of somatostatin hormones are mediated by a family of five different seven-helix transmembrane spanning receptors (SSTR1-5). The expression of the five different SSTR subtypes displays a...

Poorly differentiated colonic adenocarcinoma, medullary type: clinical, phenotypic, and molecular characteristics.

Rüschoff, J., Dietmaier, W., Lüttges, J., Seitz, G., Bocker, T., Zirngibl, H., ...

Clinicopathological evidence has accumulated that colorectal adenocarcinoma with minimal or no glandular differentiation constitutes two entities with different prognosis. In a series of 20...

Gene expression pattern of laser microdissected colonic crypts of adenomas with low grade dysplasia

Lechner, S, Müller-Ladner, U, Renke, B, Schölmerich, J, Rüschoff, J, Kullmann, F

Background and aims: Colorectal epithelial cells are prone to malignant transformation. Therefore, identification of differences in gene expression in the process from normal colonic crypts to...

Pancreatic acinar cell carcinoma. An analysis of cell lineage markers, p53 expression, and Ki-ras mutation.

Hoorens, A., Lemoine, N. R., McLellan, E., Morohoshi, T., Kamisawa, T., Heitz, P. U., ...

In a series of 22 pancreatic acinar cell carcinomas, including two acinar cystadenocarcinomas, cellular differentiation was analyzed by immunocytochemistry and electron microscopy. In addition,...

Expression of IGF‐I, IGF‐II, and IGF‐IR in gallbladder carcinoma. A systematic analysis including primary and corresponding metastatic tumours

Kornprat, P, Rehak, P, Rüschoff, J, Langner, C

EGFR fluorescence in situ hybridisation assay: guidelines for application to non-small-cell lung cancer

Varella-Garcia, M, Diebold, J, Eberhard, D A, Geenen, K, Hirschmann, A, Kockx, M, ...

There is a need for predictive biomarkers that identify non-small-cell lung cancer (NSCLC) patients most likely to respond to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI)...