J. W. Fisher

Details der Publikationsliste

Zeitraum

1854 - 2008

Anzahl

39

Co-Autoren

Reducing Dietary Phosphorus in Dairy Rations. (2008)

Fisher, J.W., Sharpe, P., McKnight, D., KoekKoek, A., France, J., McBride, B.W., ...

Objective: Long term effects of feeding diet without mineral phosphorus supplementation on the performance and phosphus excretion in high yielding dairy cows and the economic implications of reducing...

Robotic Milking Systems for Dairy Cows in Ontario : Economics, Milk Quality, Nutritional Enticers (2008)

Fisher, J.W., McKnight, D.R., Rodenburg, J.

Objectives: To compare robotic milking with conventional parlour milking for costs and production efficiency; To monitor raw milk quality and to locate the sources of deteriation if exists; To...

Economics of Longevity in Dairy Cattle (2008)

Fisher, J.W.

Poster/Factsheet provides program objectives, findings and conclusions of this study.

Effects of Perchlorate on Thyroidal Uptake of Iodide with Corresponding Hormonal Changes (2006)

Yun, K. O., Todd, P. N., Young, S. M., Mattie, D. R., Fisher, J. W., Narayanan, L., ...

Perchlorate interferes with iodide accumulation in the thyroid resulting in reduced thyroidal hormone synthesis. The objective of this project was to conduct a series of experiments to investigate...

Pharmacokinetics and Metabolism of Dichloroacetic Acid and Trichloroacetic Acid Administered in Drinking Water in Rats and Mice (2006)

Godrey, R. J., Buttler, G. W., Narayanan, L., Fisher, J. W., Taylor, A.

As by-products of water chlorination, dichloroacetic acid (DCA) and trichloroacetic acid (TCA) are ubiquitous contaminants of drinking water supplies. They are also major metabolites of several...

Acute and Behavioral Effects of Hydrazine on 'Lepomis macrochirus' (2006)

Fisher, J. W., Harrah, C. B., Weaver, L. K., Wingo, W. I.

This study was designed to provide baseline information about the acute lethal and sublethal effects of hydrazine (H2NNH2) upon the bluegill, Lepomis macrochirus. An LC50 value of hydrazine with...

Continuous Flow Aquatic Toxicity Testing Using Dilution Water by Reverse Osmosis (2006)

Fisher, J. W., Inman, R. C., Hagerman, M. A., Harrah, C. B.

This paper describes the design and operation of a continuous-flow aquatic toxicity testing system. Aquatic organisms are exposed to toxic chemicals in exposure tanks in which fresh water plus...

The Effects of Selected Aquatic Sediments on the Acute Toxicity of N- Nitrosodimethylamine to Gammarus Limnaeus (2006)

Fisher, J. W.

This study was designed to provide information concerning the acute toxicity effects of N-nitrosodimethylamine to Gammarus limnaeus in the presence of two types of aquatic sediments. Analytical...

The Effects of Selected Hydrazines Upon Fish and Invertebrates (2006)

Fisher, J. W., Myers, D. S., Meyers, M. L.

The toxicity of hydrazine, monomethylhydrazine, and 1-1, dimethylhydrazine was ascertained from static LC50 estimations using two freshwater fish, golden shiners and channel catfish, and two...

Effect of PCB 126 on Hepatic Metabolism of Thyroxine and Perturbations in the Hypothalamic-Pituitary-Thyroid Axis in the Rat (2005)

Fisher, J W, Campbell, J, Muralidhara, S, Bruckner, J V, Ferguson, D, Mumtaz, M, ...

The objective of this research was to examine the time- and dose- dependent disturbances in the hypothalamic-pituitary-thyroid (HPT) axis of adult male rats administered a potent coplanar (non-ortho)...

Fatigue Crack Growth in Welded Beams, (1998)

Hirt,M. A., Fisher,J. W.

The fatigue behavior of welded steel beams is evaluated using the fracture mechanics concepts of stable crack growth. A fracture mechanics model for cracks originating from the pores in the...

'Occupational' Exposure of Infants to Toxic Chemicals via Breast Milk. (1998)

Byczkowski, J. Z., Gearhart, J. M., Fisher, J. W.

The transfer of toxic chemicals to breast milk represents an important, although not widely recognized, chemical exposure route for the infant. For an increasing number of nursing mothers who resume...

Rat to Human Extrapolation of HCFC-123 Kinetics Deduced from Halothane Kinetics: A Corollary Approach to Physiologically Based Pharmacokinetic Modeling (1996)

WILLIAMS, R. J., VINEGAR, A., MCDOUGAL, J. N., JARABEK, A. M., FISHER, J. W.

The goal of this study was to develop a human physiologically based pharmacokinetic (PBPK) model for the chemical HCFC-123 (2,2-dlchloro-1,1,1-trifluoroethane) and its major metabolite,...

Determination of Skin:Air Partition Coefficients for Volatile Chemicals: Experimental Method and Applications (1994)

MATTIE, D. R., BATES, G. D., JEPSON, G. W., FISHER, J. W., MCDOUGAL, J. N.

The partition coefficient (PC) of a chemical in skin is an indicator of the capacity for a chemical in the skin and may reflect the rate at which a chemical penetrates the skin and enters into...

Interaction of nitric oxide and cyclic guanosine 3',5'-monophosphate in erythropoietin production.

Ohigashi, T, Brookins, J, Fisher, J W

The present study was designed to investigate whether in vivo and in vitro erythropoietin (EPO) production is modulated by nitric oxide (NO) and cyclic guanosine 3',5'-monophosphate (cGMP). Serum...

Role of endogenous prostaglandin E2 in erythropoietin production and dome formation by human renal carcinoma cells in culture.

Hagiwara, M, McNamara, D B, Chen, I L, Fisher, J W

Studies were carried out on the role of endogenous prostaglandin E2 (PGE2) in erythropoietin (Ep) production and dome formation in primary monolayer cultures of a human renal carcinoma from a patient...

Methods to identify and characterize developmental neurotoxicity for human health risk assessment. III: pharmacokinetic and pharmacodynamic considerations.

Dorman, D C, Allen, S L, Byczkowski, J Z, Claudio, L, Fisher, J E, Fisher, J W, ...

We review pharmacokinetic and pharmacodynamic factors that should be considered in the design and interpretation of developmental neurotoxicity studies. Toxicologic effects on the developing nervous...

Trichloroethene levels in human blood and exhaled breath from controlled inhalation exposure.

Pleil, J D, Fisher, J W, Lindstrom, A B

The organic constituents of exhaled human breath are representative of bloodborne concentrations through gas exchange in the blood/breath interface in the lungs. The presence of specific compounds...

Physiologically based pharmacokinetic models for trichloroethylene and its oxidative metabolites.

Fisher, J W

Trichloroethylene (TCE) pharmacokinetics have been studied in experimental animals and humans for over 30 years. Compartmental and physiologically based pharmacokinetic (PBPK) models have been...

Metabolism of trichloroethylene.

Lash, L H, Fisher, J W, Lipscomb, J C, Parker, J C

A major focus in the study of metabolism and disposition of trichloroethylene (TCE) is to identify metabolites that can be used reliably to assess flux through the various pathways of TCE metabolism...

Interaction of nitric oxide and cyclic guanosine 3',5'-monophosphate in erythropoietin production.

Ohigashi, T, Brookins, J, Fisher, J W

The present study was designed to investigate whether in vivo and in vitro erythropoietin (EPO) production is modulated by nitric oxide (NO) and cyclic guanosine 3',5'-monophosphate (cGMP). Serum...

Role of endogenous prostaglandin E2 in erythropoietin production and dome formation by human renal carcinoma cells in culture.

Hagiwara, M, McNamara, D B, Chen, I L, Fisher, J W

Studies were carried out on the role of endogenous prostaglandin E2 (PGE2) in erythropoietin (Ep) production and dome formation in primary monolayer cultures of a human renal carcinoma from a patient...

Methods to identify and characterize developmental neurotoxicity for human health risk assessment. III: pharmacokinetic and pharmacodynamic considerations.

Dorman, D C, Allen, S L, Byczkowski, J Z, Claudio, L, Fisher, J E, Fisher, J W, ...

We review pharmacokinetic and pharmacodynamic factors that should be considered in the design and interpretation of developmental neurotoxicity studies. Toxicologic effects on the developing nervous...

Trichloroethene levels in human blood and exhaled breath from controlled inhalation exposure.

Pleil, J D, Fisher, J W, Lindstrom, A B

The organic constituents of exhaled human breath are representative of bloodborne concentrations through gas exchange in the blood/breath interface in the lungs. The presence of specific compounds...

Physiologically based pharmacokinetic models for trichloroethylene and its oxidative metabolites.

Fisher, J W

Trichloroethylene (TCE) pharmacokinetics have been studied in experimental animals and humans for over 30 years. Compartmental and physiologically based pharmacokinetic (PBPK) models have been...

Metabolism of trichloroethylene.

Lash, L H, Fisher, J W, Lipscomb, J C, Parker, J C

A major focus in the study of metabolism and disposition of trichloroethylene (TCE) is to identify metabolites that can be used reliably to assess flux through the various pathways of TCE metabolism...