[Hepatitis E: from zoonotic transmission to chronic infection in immunosuppressed patients.] (2008)
Izopet, Jacques, Kamar, Nassim
Pendant longtemps considérée comme une hépatite virale aiguë d'origine hydrique évoluant selon un mode épidémique dans les régions tropicales et subtropicales, l'hépatite E est de plus en...
[Hepatitis E: from zoonotic transmission to chronic infection in immunosuppressed patients.] (2008)
Izopet, Jacques, Kamar, Nassim
Pendant longtemps considérée comme une hépatite virale aiguë d'origine hydrique évoluant selon un mode épidémique dans les régions tropicales et subtropicales, l'hépatite E est de plus en...
[Hepatitis E: from zoonotic transmission to chronic infection in immunosuppressed patients.] (2008)
Izopet, Jacques, Kamar, Nassim
Pendant longtemps considérée comme une hépatite virale aiguë d'origine hydrique évoluant selon un mode épidémique dans les régions tropicales et subtropicales, l'hépatite E est de plus en...
Descamps, Diane, Assoumou, Lambert, Masquelier, Bernard, Marcelin, Anne-Geneviève, Saidi, Souhila, Tamalet, Catherine, ...
Objectives We studied gp41 mutations associated with failing enfuvirtide salvage therapy. Methods This multicentre study involved patients with HIV-1 plasma viral load (pVL) > 5000 copies/mL after...
Wéclawiack, Hugo, Kamar, Nassim, Mehrenberger, Marion, Guilbeau-Frugier, Céline, Modesto, Anne, Izopet, Jacques, ...
Background. In hepatitis C virus (HCV) positive kidney transplant (KT) patients, the use of alpha-interferon (αIFN) is contraindicated due to the risk of acute rejection (AR). Conversely, if these...
Alpers, Charles, Bloom, Roy D., Fabrizi, Fabrizio, Izopet, Jacques, Jadoul, Michel, Lindley, Elizabeth, ...
[Hepatitis E: from zoonotic transmission to chronic infection in immunosuppressed patients.] (2008)
Izopet, Jacques, Kamar, Nassim
Pendant longtemps considérée comme une hépatite virale aiguë d'origine hydrique évoluant selon un mode épidémique dans les régions tropicales et subtropicales, l'hépatite E est de plus en...
[Hepatitis E: from zoonotic transmission to chronic infection in immunosuppressed patients.] (2008)
Izopet, Jacques, Kamar, Nassim
Pendant longtemps considérée comme une hépatite virale aiguë d'origine hydrique évoluant selon un mode épidémique dans les régions tropicales et subtropicales, l'hépatite E est de plus en...
[Hepatitis E: from zoonotic transmission to chronic infection in immunosuppressed patients.] (2008)
Izopet, Jacques, Kamar, Nassim
Pendant longtemps considérée comme une hépatite virale aiguë d'origine hydrique évoluant selon un mode épidémique dans les régions tropicales et subtropicales, l'hépatite E est de plus en...
Hépatite C : transmission nosocomiale, état de santé et devenir des personnes atteintes (2003)
Bronowicki, Jean-Pierre, Daurès, Jean-Pierre, Deuffic-Burban, Sylvie, Dhumeaux, Daniel, Izopet, Jacques, Leplège, Alain, ...
257 pages, tableaux, graphiques
Lesourd, Florence, Izopet, Jacques, Mervan, Cécile, Payen, Jean-Louis, Sandres, Karine, Monrozies, Xavier, ...
Since mother to child transmissions of hepatitis C virus (HCV) have been reported to be low, teams involved in assisted reproductive technologies have accepted HCV positive patients into their...
Masquelier, Bernard, Race, Esther, Tamalet, Catherine, Descamps, Diane, Izopet, Jacques, Buffet-Janvresse, Claudine, ...
Genomic rearrangements in the 5′ part of the human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) have been involved in multidrug resistance to nucleoside RT inhibitors (NRTI). We...
Segondy, Michel, Izopet, Jacques, Pellegrin, Isabelle, Montes, Brigitte, Dumon, Beatrice, Pasquier, Christophe, ...
We compared the QUANTIPLEX HIV-1 RNA 2.0 assay with the AMPLICOR HIV-1 MONITOR 1.0 assay for quantitation of human immunodeficiency virus type 1 (HIV-1) RNA in plasma in the Stadi trail, which...
Hance, Allan J., Lemiale, Virginie, Izopet, Jacques, Lecossier, Denise, Joly, Véronique, Massip, Patrice, ...
Mutations in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase and protease that confer resistance to antiretroviral agents are usually accompanied by a reduction in the viral...
Multicenter Quality Control for the Detection of Hepatitis C Virus RNA in Seminal Plasma Specimens
Bourlet, Thomas, Levy, Rachel, Laporte, Silvy, Blachier, Stéphane, Bocket, Laurence, Cassuto, Guy, ...
The discrepant results available in the literature about the presence of hepatitis C virus (HCV) RNA in seminal plasma of men chronically infected by this agent are related, at least in part, to the...
Immunologically Silent Autochthonous Acute Hepatitis E Virus Infection in France
Mansuy, Jean Michel, Peron, Jean Marie, Bureau, Christophe, Alric, Laurent, Vinel, Jean Pierre, Izopet, Jacques
Hepatitis E is an acute and self-limiting hepatitis, and the causative agent, hepatitis E virus, is excreted in feces and orally transmitted. The disease is common in Asia and Africa, causing...
Lefrère, Jean-Jacques, Roudot-Thoraval, Françoise, Lunel, Françoise, Alain, Sophie, Chaix, Marie-Laure, Dussaix, Elisabeth, ...
Before initiating new large-scale therapeutic trials for hepatitis C virus (HCV)-infected patients, the French Health Authorities for HCV research decided to organize an evaluation of the expertise...
Convenient Biological Assay for Polyethylene Glycol-Interferons in Patients with Hepatitis C
Boulestin, Anne, Kamar, Nassim, Legrand-Abravanel, Florence, Sandres-Saune, Karine, Alric, Laurent, Vinel, Jean-Pierre, ...
The vesicular stomatitis virus cytopathic effect reduction assay is suitable to quantify polyethylene glycol-alpha interferon 2a (PEG-IFN-α2a) and PEG-IFN-α2b. Human serum and ribavirin did not...
Comparison of Hepatitis C Virus NS5b and 5′ Noncoding Gene Sequencing Methods in a Multicenter Study
Laperche, Syria, Lunel, Françoise, Izopet, Jacques, Alain, Sophie, Dény, Paul, Duverlie, Gilles, ...
A national evaluation study was performed in 11 specialized laboratories with the objective of assessing their capacities to genotype hepatitis C virus (HCV) and define the applicability of a given...
Marcelin, Anne-Geneviève, Cohen-Codar, Isabelle, King, Martin S., Colson, Philippe, Guillevic, Emmanuel, Descamps, Diane, ...
The genotypic inhibitory quotient (GIQ) has been proposed as a way to integrate drug exposure and genotypic resistance to protease inhibitors and can be useful to enhance the predictivity of...
Laperche, Syria, Saune, Karine, Dény, Paul, Duverlie, Gilles, Alain, Sophie, Chaix, Marie-Laure, ...
A multicenter study of NS5b hepatitis C virus (HCV) genotype determination involving 12 laboratories demonstrates that any laboratory with expertise in sequencing techniques would be able to provide...
Masquelier, Bernard, Race, Esther, Tamalet, Catherine, Descamps, Diane, Izopet, Jacques, Buffet-Janvresse, Claudine, ...
Genomic rearrangements in the 5′ part of the human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT) have been involved in multidrug resistance to nucleoside RT inhibitors (NRTI). We...
Segondy, Michel, Izopet, Jacques, Pellegrin, Isabelle, Montes, Brigitte, Dumon, Beatrice, Pasquier, Christophe, ...
We compared the QUANTIPLEX HIV-1 RNA 2.0 assay with the AMPLICOR HIV-1 MONITOR 1.0 assay for quantitation of human immunodeficiency virus type 1 (HIV-1) RNA in plasma in the Stadi trail, which...
Hance, Allan J., Lemiale, Virginie, Izopet, Jacques, Lecossier, Denise, Joly, Véronique, Massip, Patrice, ...
Mutations in human immunodeficiency virus type 1 (HIV-1) reverse transcriptase and protease that confer resistance to antiretroviral agents are usually accompanied by a reduction in the viral...
Multicenter Quality Control for the Detection of Hepatitis C Virus RNA in Seminal Plasma Specimens
Bourlet, Thomas, Levy, Rachel, Laporte, Silvy, Blachier, Stéphane, Bocket, Laurence, Cassuto, Guy, ...
The discrepant results available in the literature about the presence of hepatitis C virus (HCV) RNA in seminal plasma of men chronically infected by this agent are related, at least in part, to the...
Immunologically Silent Autochthonous Acute Hepatitis E Virus Infection in France
Mansuy, Jean Michel, Peron, Jean Marie, Bureau, Christophe, Alric, Laurent, Vinel, Jean Pierre, Izopet, Jacques
Hepatitis E is an acute and self-limiting hepatitis, and the causative agent, hepatitis E virus, is excreted in feces and orally transmitted. The disease is common in Asia and Africa, causing...
Lefrère, Jean-Jacques, Roudot-Thoraval, Françoise, Lunel, Françoise, Alain, Sophie, Chaix, Marie-Laure, Dussaix, Elisabeth, ...
Before initiating new large-scale therapeutic trials for hepatitis C virus (HCV)-infected patients, the French Health Authorities for HCV research decided to organize an evaluation of the expertise...
Convenient Biological Assay for Polyethylene Glycol-Interferons in Patients with Hepatitis C
Boulestin, Anne, Kamar, Nassim, Legrand-Abravanel, Florence, Sandres-Saune, Karine, Alric, Laurent, Vinel, Jean-Pierre, ...
The vesicular stomatitis virus cytopathic effect reduction assay is suitable to quantify polyethylene glycol-alpha interferon 2a (PEG-IFN-α2a) and PEG-IFN-α2b. Human serum and ribavirin did not...
Comparison of Hepatitis C Virus NS5b and 5′ Noncoding Gene Sequencing Methods in a Multicenter Study
Laperche, Syria, Lunel, Françoise, Izopet, Jacques, Alain, Sophie, Dény, Paul, Duverlie, Gilles, ...
A national evaluation study was performed in 11 specialized laboratories with the objective of assessing their capacities to genotype hepatitis C virus (HCV) and define the applicability of a given...
Marcelin, Anne-Geneviève, Cohen-Codar, Isabelle, King, Martin S., Colson, Philippe, Guillevic, Emmanuel, Descamps, Diane, ...
The genotypic inhibitory quotient (GIQ) has been proposed as a way to integrate drug exposure and genotypic resistance to protease inhibitors and can be useful to enhance the predictivity of...
Laperche, Syria, Saune, Karine, Dény, Paul, Duverlie, Gilles, Alain, Sophie, Chaix, Marie-Laure, ...
A multicenter study of NS5b hepatitis C virus (HCV) genotype determination involving 12 laboratories demonstrates that any laboratory with expertise in sequencing techniques would be able to provide...
Delobel, Pierre, Nugeyre, Marie-Thérèse, Cazabat, Michelle, Sandres-Sauné, Karine, Pasquier, Christophe, Cuzin, Lise, ...
The reasons for poor CD4+ T-cell recovery in some human immunodeficiency virus (HIV)-infected subjects despite effective highly active antiretroviral therapy (HAART) remain unclear. We recently...
New Natural Intergenotypic (2/5) Recombinant of Hepatitis C Virus▿
Legrand-Abravanel, Florence, Claudinon, Julie, Nicot, Florence, Dubois, Martine, Chapuy-Regaud, Sabine, Sandres-Saune, Karine, ...
A 9.2-kb sequence from a hepatitis C virus (HCV) strain found in southwest France was compared to sequences from reference strains in HCV sequence databases. We found a recombinant virus with...
Delobel, Pierre, Nugeyre, Marie-Thérèse, Cazabat, Michelle, Pasquier, Christophe, Marchou, Bruno, Massip, Patrice, ...
Genotypic population-based methods could be faster and less expensive than phenotypic recombinant assays for determining human immunodeficiency virus type 1 (HIV-1) coreceptor usage in patient...
A pharmacokinetic model for alpha interferon administered subcutaneously
Chatelut, Etienne, Rostaing, Lionel, Grégoire, Nicolas, Payen, Jean-Louis, Pujol, André, Izopet, Jacques, ...
Multicenter Trials Need To Use the Same Assay for Hepatitis C Virus Viral Load Determination▿
Laperche, Syria, Bouchardeau, Françoise, Thibault, Vincent, Pozzetto, Bruno, Vallet, Sophie, Rosenberg, Arielle R., ...
This study, involving 20 laboratories and using currently available assays for hepatitis C virus RNA quantification, demonstrated that differences in viral load values are due not to interlaboratory...
Tipranavir-Ritonavir Genotypic Resistance Score in Protease Inhibitor-Experienced Patients▿
Marcelin, Anne-Genevieve, Masquelier, Bernard, Descamps, Diane, Izopet, Jacques, Charpentier, Charlotte, Alloui, Chakib, ...
To identify mutations associated with the virological response (VR) to a tipranavir-ritonavir (TPV/r)-based regimen, 143 patients previously treated with protease inhibitor (PI) were studied. VR was...
Hepatitis E Virus Genotype 3 Diversity, France
Legrand-Abravanel, Florence, Mansuy, Jean-Michel, Dubois, Martine, Kamar, Nassim, Peron, Jean-Marie, Rostaing, Lionel, ...
We characterized 42 hepatitis E virus (HEV) genotype 3 strains from infected patients in France in 3 parts of the genome and sequenced the full-length HEV genotype 3f genome found in Europe. These...
Mavigner, Maud, Delobel, Pierre, Cazabat, Michelle, Dubois, Martine, L'Faqihi-Olive, Fatima-Ezzahra, Raymond, Stéphanie, ...
Good Performance of Immunoglobulin M Assays in Diagnosing Genotype 3 Hepatitis E Virus Infections▿
Legrand-Abravanel, Florence, Thevenet, Isabelle, Mansuy, Jean-Michel, Saune, Karine, Vischi, Françoise, Peron, Jean-Marie, ...
We have evaluated three anti-hepatitis E virus (anti-HEV) immunoglobulin M (IgM) assays, the EIAgen HEV IgM assay (Adaltis), the HEV IgM enzyme-linked immunosorbent assay 3.0, and the Assure HEV IgM...
Genotypic Prediction of Human Immunodeficiency Virus Type 1 CRF02-AG Tropism▿
Raymond, Stéphanie, Delobel, Pierre, Mavigner, Maud, Cazabat, Michelle, Souyris, Corinne, Encinas, Stéphanie, ...
We assessed the performance of genotypic algorithms for predicting the tropism of human immunodeficiency virus type 1 coreceptor usage in 52 patients infected with the CRF02-AG subtype. The combined...
Pasquier, Christophe, Sauné, Karine, Raymond, Stéphanie, Moinard, Nathalie, Daudin, Myriam, Bujan, Louis, ...
The semen plasma virus load is measured to ensure the safety of sperm processing during medically assisted procreation (MAP) for couples with a human immunodeficiency virus type 1 (HIV-1)-infected...