Patterson, Michael, Sneyd, James, Friel, David D.
Many models have been developed to account for stimulus-evoked [Ca(2+)] responses, but few address how responses elicited in specific cell types are defined by the Ca(2+) transport and buffering...
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A simple method for high temporal resolution calcium imaging with dual excitation dyes (1998)
Luc Leybaert, James Sneyd, Michael J. S
ABSTRACT Calcium-sensitive dual excitation dyes, such as fura-2, are now widely used to measure the free calcium concentration ([Ca 2 �]) in living cells. Preferentially, [Ca 2 � ] is calculated...
On the propagation of calcium waves in an inhomogeneous medium (1997)
James Sneyd, Jonathan Sherratt
Abstract. Although the exact details are disputed, it is well established that propagating waves of increased intracellular free Ca 2+ concentration arise from a positive feedback or autocatalytic...
A dynamic model of the type-2 inositol trisphosphate receptor
Sneyd, James, Dufour, Jean-François
The dynamic properties of the inositol (1,4,5)-trisphosphate (IP3) receptor are crucial for the control of intracellular Ca2+, including the generation of Ca2+ oscillations and waves. However, many...
A dynamic model of the type-2 inositol trisphosphate receptor
Sneyd, James, Dufour, Jean-François
The dynamic properties of the inositol (1,4,5)-trisphosphate (IP3) receptor are crucial for the control of intracellular Ca2+, including the generation of Ca2+ oscillations and waves. However, many...
A Buffering SERCA Pump in Models of Calcium Dynamics
Higgins, Erin R., Cannell, Mark B., Sneyd, James
Many cells use oscillations in calcium concentration to transmit messages. The oscillations largely result from an influx of calcium into the cytosol from the endoplasmic reticulum (ER), followed by...
Patterson, Michael, Sneyd, James, Friel, David D.
Many models have been developed to account for stimulus-evoked [Ca2+] responses, but few address how responses elicited in specific cell types are defined by the Ca2+ transport and buffering systems...
Giovannucci, David R, Bruce, Jason I. E, Straub, Stephen V, Arreola, Jorge, Sneyd, James, Shuttleworth, Trevor J, ...
The dynamics of Ca2+ release and Ca2+-activated Cl− currents in two related, but functionally distinct exocrine cells, were studied to gain insight into how the molecular specialization of Ca2+...
LeBeau, Andrew P., Yule, David I., Groblewski, Guy E., Sneyd, James
The properties of inositol 1,4,5-trisphosphate (IP3)-dependent intracellular calcium oscillations in pancreatic acinar cells depend crucially on the agonist used to stimulate them. Acetylcholine or...
A Mathematical Model of Airway and Pulmonary Arteriole Smooth Muscle
Wang, Inga, Politi, Antonio Z., Tania, Nessy, Bai, Yan, Sanderson, Michael J., Sneyd, James
Airway hyperresponsiveness is a major characteristic of asthma and is believed to result from the excessive contraction of airway smooth muscle cells (SMCs). However, the identification of the...