Jean Hausser

MirZ: an integrated microRNA expression atlas and target prediction resource (2009)

Hausser, Jean, Berninger, Philipp, Rodak, Christoph, Jantscher, Yvonne, Wirth, Stefan, Zavolan, Mihaela

MicroRNAs (miRNAs) are short RNAs that act as guides for the degradation and translational repression of protein-coding mRNAs. A large body of work showed that miRNAs are involved in the regulation...

Relative contribution of sequence and structure features to the mRNA binding of Argonaute/EIF2C-miRNA complexes and the degradation of miRNA targets (2009)

Hausser, Jean, Landthaler, Markus, Jaskiewicz, Lukasz, Gaidatzis, Dimos, Zavolan, Mihaela

How miRNAs recognize their target sites is a puzzle that many experimental and computational studies aimed to solve. Several features, such as perfect pairing of the miRNA seed, additional pairing in...

Entropy inference and the James-Stein estimator, with application to nonlinear gene association networks (2008)

Hausser, Jean, Strimmer, Korbinian

We present a procedure for effective estimation of entropy and mutual information from small-sample data, and apply it to the problem of inferring high-dimensional gene association networks....

Inference of miRNA targets using evolutionary conservation and pathway analysis (2007)

Gaidatzis, Dimos, Van Nimwegen, Erik, Hausser, Jean, Zavolan, Mihaela

Abstract Background MicroRNAs have emerged as important regulatory genes in a variety of cellular processes and, in recent years, hundreds of such genes have been discovered in animals. In contrast,...

pathway analysis (2007)

Bmc Bioinformatics, Dimos Gaidatzis, Erik Van Nimwegen, Jean Hausser, Mihaela Zavolan

Inference of miRNA targets using evolutionary conservation and

Improving Entropy Estimation and the Inference of Genetic Regulatory Networks (2006)

Jean Hausser, Dépt Biosciences, Bâtiment Louis Pasteur, Avenue Jean Capelle

This paper explores how entropy and other information theoretic quantities may be used to reverseengineer genetic regulatory networks from repeated microarray data. The problem of differentiating...

Improving Entropy Estimation and the Inference of Genetic Regulatory Networks (2006)

Jean Hausser, Dépt Biosciences, Bâtiment Louis Pasteur, Avenue Jean Capelle

This paper explores how entropy and other information theoretic quantities may be used to reverseengineer genetic regulatory networks from repeated microarray data. The problem of differentiating...

miR-375 maintains normal pancreatic α- and β-cell mass

Poy, Matthew N., Hausser, Jean, Trajkovski, Mirko, Braun, Matthias, Collins, Stephan, Rorsman, Patrik, ...

Altered growth and development of the endocrine pancreas is a frequent cause of the hyperglycemia associated with diabetes. Here we show that microRNA-375 (miR-375), which is highly expressed in...

MirZ: an integrated microRNA expression atlas and target prediction resource

Hausser, Jean, Berninger, Philipp, Rodak, Christoph, Jantscher, Yvonne, Wirth, Stefan, Zavolan, Mihaela

MicroRNAs (miRNAs) are short RNAs that act as guides for the degradation and translational repression of protein-coding mRNAs. A large body of work showed that miRNAs are involved in the regulation...