Jeffrey W. Orr

Ligand-induced conformational changes observed in single RNA molecules

Ha, Taekjip, Zhuang, Xiaowei, Kim, Harold D., Orr, Jeffrey W., Williamson, James R., Chu, Steven

We present the first demonstration that fluorescence resonance energy transfer can be used to track the motion of a single molecule undergoing conformational changes. As a model system, the...

Mg2+-dependent conformational change of RNA studied by fluorescence correlation and FRET on immobilized single molecules

Kim, Harold D., Nienhaus, G. Ulrich, Ha, Taekjip, Orr, Jeffrey W., Williamson, James R., Chu, Steven

Fluorescence correlation spectroscopy (FCS) of fluorescence resonant energy transfer (FRET) on immobilized individual fluorophores was used to study the Mg2+-facilitated conformational change of an...

Ligand-induced conformational changes observed in single RNA molecules

Ha, Taekjip, Zhuang, Xiaowei, Kim, Harold D., Orr, Jeffrey W., Williamson, James R., Chu, Steven

We present the first demonstration that fluorescence resonance energy transfer can be used to track the motion of a single molecule undergoing conformational changes. As a model system, the...

Mg2+-dependent conformational change of RNA studied by fluorescence correlation and FRET on immobilized single molecules

Kim, Harold D., Nienhaus, G. Ulrich, Ha, Taekjip, Orr, Jeffrey W., Williamson, James R., Chu, Steven

Fluorescence correlation spectroscopy (FCS) of fluorescence resonant energy transfer (FRET) on immobilized individual fluorophores was used to study the Mg2+-facilitated conformational change of an...