Chemical modification resolves the asymmetry of siRNA strand degradation in human blood serum (2007)
Hoerter, John A.H., Walter, Nils G.
Small interfering (si)RNAs have recently been used to therapeutically silence genes in vivo after intravenous systemic delivery. Further progress in the development of siRNA therapeutics will in part...
Solution probing of metal ion binding by helix 27 from Escherichia coli 16S rRNA (2005)
LAMBERT, MEREDITH NEWBY, HOERTER, JOHN A.H., PEREIRA, MIGUEL J.B., WALTER, NILS G.
Helix (H)27 from Escherichia coli 16S ribosomal (r)RNA is centrally located within the small (30S) ribosomal subunit, immediately adjacent to the decoding center. Bacterial 30S subunit crystal...
Solution probing of metal ion binding by helix 27 from Escherichia coli 16S rRNA
LAMBERT, MEREDITH NEWBY, HOERTER, JOHN A.H., PEREIRA, MIGUEL J.B., WALTER, NILS G.
Helix (H)27 from Escherichia coli 16S ribosomal (r)RNA is centrally located within the small (30S) ribosomal subunit, immediately adjacent to the decoding center. Bacterial 30S subunit crystal...
Solution probing of metal ion binding by helix 27 from Escherichia coli 16S rRNA
LAMBERT, MEREDITH NEWBY, HOERTER, JOHN A.H., PEREIRA, MIGUEL J.B., WALTER, NILS G.
Helix (H)27 from Escherichia coli 16S ribosomal (r)RNA is centrally located within the small (30S) ribosomal subunit, immediately adjacent to the decoding center. Bacterial 30S subunit crystal...
Chemical modification resolves the asymmetry of siRNA strand degradation in human blood serum
Hoerter, John A.H., Walter, Nils G.
Small interfering (si)RNAs have recently been used to therapeutically silence genes in vivo after intravenous systemic delivery. Further progress in the development of siRNA therapeutics will in part...
Dynamics, Degradation, and Chemical Modification of Non-Coding RNA
Our understanding of the function of RNA has grown significantly since the central dogma of molecular biology described RNA as a rudimentary conveyor of the genetic message. In the genomic era, we...