Sexual Behavior activity tracks rapid changes in brain estrogen concentrations (2007)
Taziaux, Mélanie, Keller, Matthieu, Bakker, Julie, Balthazart, Jacques
Estrogens are classically viewed as hormones that bind to intracellular receptors, which then act as transcription factors to modulate gene expression; however, they also affect many aspects of...
Bakker, Julie, De Mees, C, Szpirer, J, Szpirer, C, Balthazart, Jacques
The neural mechanisms controlling mate recognition and heterosexual partner preference are sexually differentiated by perinatal actions of sex steroid hormones. We previously showed that the most...
Bakker, Julie, De Mees, C, Douhard, Quentin, Balthazart, Jacques, Gabant, P, Szpirer, J, ...
Two clearly opposing views exist on the function of alpha-fetoprotein (AFP), a fetal plasma protein that binds estrogens with high affinity, in the sexual differentiation of the rodent brain. AFP has...
Pierman, S, Douhard, Quentin, Balthazart, Jacques, Baum, MJ, Bakker, Julie
We previously found that both male and female aromatase knockout (ArKO) mice, which cannot synthesize estrogens due to a targeted mutation of the aromatase gene, showed less investigation of volatile...
Keller, Matthieu, Douhard, Quentin, Baum, Michael J., Bakker, Julie
We studied the contribution of the main olfactory system to mate recognition and sexual behavior in female mice. Female mice received an intranasal irrigation of either a zinc sulfate (ZnSO4)...
Keller, Matthieu, Douhard, Quentin, Baum, Michael J., Bakker, Julie
Recent studies point to an important role for the main olfactory epithelium (MOE) in regulating sexual behavior in male mice. We asked whether sexual experience could compensate for the disruptive...
Keller, Matthieu, Douhard, Quentin, Baum, Michael J., Bakker, Julie
Recent studies point to an important role for the main olfactory epithelium (MOE) in regulating sexual behavior in male mice. We asked whether sexual experience could compensate for the disruptive...
Keller, Matthieu, Douhard, Quentin, Baum, Michael J., Bakker, Julie
We studied the contribution of the main olfactory system to mate recognition and sexual behavior in female mice. Female mice received an intranasal irrigation of either a zinc sulfate (ZnSO4)...
Keller, Matthieu, Douhard, Quentin, Baum, Michael J., Bakker, Julie
Recent studies point to an important role for the main olfactory epithelium (MOE) in regulating sexual behavior in male mice. We asked whether sexual experience could compensate for the disruptive...
Dalla, C, Antoniou, K, Papadopoulou-Daifoti, Z, Balthazart, Jacques, Bakker, Julie
It is well known that estradiol derived from neural aromatization of testosterone plays a crucial role in the development of the male brain and the display of sexual behaviors in adulthood. It was...
Lebuffe, Gilles, Vallet, Benoît, Takala, Jukka, Hartstein, Gary, Lamy, Maurice, Bakker, Julie, ...
Automated online tonometry displays a rapid, semicontinuous measurement of gastric-to-end tidal carbon dioxide (Pr-etCO(2)) as an index of gastrointestinal perfusion during surgery. Its use to...
Dalla, C, Antoniou, K, Papadopoulou-Daifoti, Z, Balthazart, Jacques, Bakker, Julie
We recently found that female aromatase knockout (ArKO) mice that are deficient in oestradiol due to a targeted mutation in the aromatase gene show deficits in sexual behaviour that cannot be...
Assessment of olfactory function in male and female aromatase knockout (ArKO) mice (2004)
Pierman, S, Douhard, Quentin, Balthazart, Jacques, Baum, MJ, Bakker, Julie
Bakker, Julie, Honda, S, Harada, N, Balthazart, Jacques
We previously found that male aromatase knockout (ArKO) mice that carry a targeted mutation in exons 1 and 2 of the CYP 19 gene and as a result cannot aromatize androgen to estrogen show impaired...
Bakker, Julie, Baillien, M, Honda, S, Harada, N, Balthazart, Jacques
The present study was carried out to determine whether aromatase knockout (ArKO) mice are completely devoid of aromatase activity in their brain and gonads and to compare aromatase activity in...
Bakker, Julie, Honda, S, Harada, N, Balthazart, Jacques
The classic view of sexual differentiation is that the male brain develops under the influence of testicular secretions, whereas the female brain develops in the absence of any hormonal stimulation....
Bakker, Julie, Honda, SI, Harada, N, Balthazart, Jacques
We used estrogen-deficient aromatase knock-out (ArKO) mice to determine whether estrogens contribute to the development of the brain and behavior in females. Female mice of three different genotypes...
Sexual partner preference requires a functional aromatase (Cyp19) gene in male mice (2002)
Bakker, Julie, Honda, S, Harada, N, Balthazart, Jacques
Sexual motivation, sexual partner preference, and sexual performance represent three different aspects of sexual behavior that are critical in determining the reproductive success of a species....
González-Martínez, David, De Mees, Christelle, Douhard, Quentin, Szpirer, Claude, Bakker, Julie
Sex differences in gonadal function are driven by either cyclical (females) or tonic (males) hypothalamic GnRH1 release and, subsequently, gonadotrophin (LH and FSH) secretion from the pituitary....
Alpha-Fetoprotein: From a Diagnostic Biomarker to a Key Role in Female Fertility
De Mees, Christelle, Bakker, Julie, Szpirer, Josiane, Szpirer, Claude
Alpha-fetoprotein (AFP) is a well-known diagnostic biomarker used in medicine to detect fetal developmental anomalies such as neural tube defects or Down’s syndrome, or to follow up the development...