K. Eguchi

Trans-pacific dust transport: integrated analysis of NASA/CALIPSO and a global aerosol transport model (2009)

K. Eguchi, I. Uno, K. Yumimoto, T. Takemura, A. Shimizu, N. Sugimoto, ...

Detailed 3-D structures of Trans-Pacific Asian dust transport occurring during 5–15 May 2007 were investigated using the NASA/CALIOP vertical-resolved measurements and a three-dimensional aerosol...

Trans-Pacific dust transport: integrated analysis of NASA/CALIPSO and a global aerosol transport model (2009)

K. Eguchi, I. Uno, K. Yumimoto, T. Takemura, A. Shimizu, N. Sugimoto, ...

Detailed 3-D structures of Trans-Pacific Asian dust transport occurring during 5–15 May 2007 were investigated using the NASA/CALIOP vertical-resolved measurements and a three-dimensional aerosol...

Elevated large-scale dust veil originated in the Taklimakan Desert: intercontinental transport and 3-dimensional structure captured by CALIPSO and regional and global models (2009)

K. Yumimoto, K. Eguchi, I. Uno, T. Takemura, Z. Liu, A. Shimizu, ...

An intense dust storm occurred during 19–20 May 2007 over the Taklimakan Desert in northwestern China. In the following days, the space-borne lidar CALIOP tracked an optically thin, highly...

Quality of life and disease-related symptoms in previously treated Japanese patients with non-small-cell lung cancer: results of a randomized phase III study (V-15-32) of gefitinib versus docetaxel (2009)

Sekine, I., Ichinose, Y., Nishiwaki, Y., Yamamoto, N., Tsuboi, M., Nakagawa, K., ...

Background: This report describes quality of life (QoL) findings of a randomized study comparing gefitinib with docetaxel in patients with advanced/metastatic pretreated non-small-cell lung cancer....

Transmission electron microscopic observation on reduction process of copper-iron spinel catalyst for steam reforming of dimethyl ether (2008)

Eguchi, K, Shimoda, N, Faungnawakij, K, Matsui, T, Kikuchi, R, Kawashima, S

Internal reforming of SOFCs - Carbon deposition on fuel electrode and subsequent deterioration of cell (2007)

Iida, T, Kawano, M, Matsui, T, Kikuchi, R, Eguchi, K

Thermodynamic analysis of carbon formation boundary and reforming performance for steam reforming of dimethyl ether (2007)

Faungnawakij, K, Kikuchi, R, Eguchi, K

Intermediate-temperature fuel cell employing CsH2PO4/SiP2O7-based composite electrolytes (2006)

Matsui, T, Kukino, T, Kikuchi, R, Eguchi, K

Chemical interaction between Pt and SnO2 and influence on adsorptive properties of carbon monoxide (2006)

Okanishi, T, Matsui, T, Takeguchi, T, Kikuchi, R, Eguchi, K

Impedance analysis for dye-sensitized solar cells with a reference electrode (2006)

Hoshikawa, T, Kikuchi, R, Eguchi, K

Novel anode materials for multi-fuel applicable solid oxide fuel cells (2006)

Kikuchi, R, Koashi, N, Matsui, T, Eguchi, K, Norby, T

Development of NO sorbents tolerant to sulfur oxides (2006)

Yamamoto, K, Kikuchi, R, Takeguchi, T, Eguchi, K

Electrochemical oxidation of CO over tin oxide supported platinum catalysts (2006)

Matsui, T, Fujiwara, K, Okanishi, T, Kikuchi, R, Takeguchi, T, Eguchi, K

Composite effect on the structure and proton conductivity for CsHSO4 electrolytes at intermediate temperatures (2006)

Muroyama, H, Matsui, T, Kikuchi, R, Eguchi, K

Composite effects of silicon pyrophosphate as a supporting matrix for CsH5(PO4)(2) electrolytes at intermediate temperatures (2006)

Matsui, T, Kukino, T, Kikuchi, R, Eguchi, K

Influence of solid-acid catalysts on steam reforming and hydrolysis of dimethyl ether for hydrogen production (2006)

Faungnawakij, K, Tanaka, Y, Shimoda, N, Fukunaga, T, Kawashima, S, Kikuchi, R, ...

Effects of electrolyte in dye-sensitized solar cells and evaluation by impedance spectroscopy (2006)

Hoshikawa, T, Ikebe, T, Kikuchi, R, Eguchi, K

Thermodynamic evaluation of methanol steam reforming for hydrogen production (2006)

Faungnawakij, K, Kikuchi, R, Eguchi, K

Effect of reduction-oxidation treatment on the catalytic activity over tin oxide supported platinum catalysts (2006)

Matsui, T, Okanishi, T, Fujiwara, K, Tsutsui, K, Kikuchi, R, Takeguchi, T, ...

Preparation of silica-modified TiO2 and application to dye-sensitized solar cells (2006)

Hoshikawa, T, Ikebe, T, Yamada, M, Kikuchi, R, Eguchi, K

Successful treatment using tacrolimus (FK506) in a patient with TNF receptor-associated periodic syndrome (TRAPS) complicated by monocytic fasciitis (2006)

Ida, H., Aramaki, T., Arima, K., Origuchi, T., Kawakami, A., Eguchi, K.

Successful treatment using tacrolimus (FK506) in a patient with TNF receptor-associated periodic syndrome (TRAPS) complicated by monocytic fasciitis (2006)

Ida, H., Aramaki, T., Arima, K., Origuchi, T., Kawakami, A., Eguchi, K.

Successful treatment using tacrolimus (FK506) in a patient with TNF receptor-associated periodic syndrome (TRAPS) complicated by monocytic fasciitis (2006)

Ida, H., Aramaki, T., Arima, K., Origuchi, T., Kawakami, A., Eguchi, K.

Measurement of Neutrino Oscillation with KamLAND: Evidence of Spectral Distortion (2005)

Araki, T., Eguchi, K., Enomoto, S., Furuno, K., Ichimura, K., Ikeda, H., ...

We present results of a study of neutrino oscillation based on a 766 ton/year exposure of KamLAND to reactor antineutrinos. We observe 258 [overline nu ]e candidate events with energies above 3.4 MeV...

Measurement of Neutrino Oscillation with KamLAND: Evidence of Spectral Distortion (2005)

Araki, T., Eguchi, K., Enomoto, S., Furuno, K., Ichimura, K., Ikeda, H., ...

We present results of a study of neutrino oscillation based on a 766 ton/year exposure of KamLAND to reactor antineutrinos. We observe 258 [overline nu ]e candidate events with energies above 3.4 MeV...

Proton conductivity and stability of Cs2HPW12O40 electrolyte at intermediate temperatures (2005)

Kukino, T, Kikuchi, R, Takeguchi, T, Matsui, T, Eguchi, K

Influence of preparation method and additive for Cu-Mn spinel oxide catalyst on water gas shift reaction of reformed fuels (2005)

Tanaka, Y, Takeguchi, T, Kikuchi, R, Eguchi, K

Steam reforming of dimethyl ether over composite catalysts of gamma-Al2O3 and Cu-based spinel (2005)

Tanaka, Y, Kikuchi, R, Takeguchi, T, Eguchi, K

Determination of dispersion of precious metals on CeO2-containing supports (2005)

Takeguchi, T, Manabe, S, Kikuchi, R, Eguchi, K, Kanazawa, T, Matsumoto, S, ...

An intermediate temperature proton-conducting electrolyte based on a CsH2PO4/SiP2O7 composite (2005)

Matsui, T, Kukino, T, Kikuchi, R, Eguchi, K

Impedance analysis for dye-sensitized solar cells with a three-electrode system (2005)

Hoshikawa, T, Yamada, M, Kikuchi, R, Eguchi, K

Impedance analysis of internal resistance affecting the photoelectrochemical performance of dye-sensitized solar cells (2005)

Hoshikawa, T, Yamada, M, Kikuchi, R, Eguchi, K

Partial oxidation of CH4 and C3H8 over hexaaluminate-type oxides (2005)

Kikuchi, R, Iwasa, Y, Takeguchi, T, Eguchi, K

Hydrogen production with integrated microchannel fuel processor using methanol for portable fuel cell systems (2005)

Park, GG, Yim, SD, Yoon, YG, Kirn, CS, Seo, DJ, Eguchi, K

Electrochemical properties and chemical stabilities of (NH4)(2)SO4/TiO2 composites at intermediate temperatures (2005)

Muroyama, H, Matsui, T, Kikuchi, R, Eguchi, K

Hydrogen production with integrated microchannel fuel processor for portable fuel cell systems (2005)

Park, GG, Yim, SD, Youn, YG, Lee, WY, Kim, CS, Seo, DJ, ...

An active metabolite of leflunomide, A77 1726, inhibits the production of serum amyloid A protein in human hepatocytes (2005)

Migita, K., Miyashita, T., Maeda, Y., Nakamura, M., Yatsuhashi, H., Ishibashi, H., ...

Objective. Cytokine-induced hepatic serum amyloid A (SAA) synthesis is the critical step in the pathogenesis of AA amyloidosis secondary to rheumatoid arthritis (RA). This study was conducted to...

An active metabolite of leflunomide, A77 1726, inhibits the production of serum amyloid A protein in human hepatocytes (2005)

Migita, K., Miyashita, T., Maeda, Y., Nakamura, M., Yatsuhashi, H., Ishibashi, H., ...

Objective. Cytokine-induced hepatic serum amyloid A (SAA) synthesis is the critical step in the pathogenesis of AA amyloidosis secondary to rheumatoid arthritis (RA). This study was conducted to...

Measurement of neutrino oscillation with Kamland: Evidence of spectral distortion (2004)

Araki, T., Eguchi, K., Enomoto, S., Furuno, K., Ichimura, K., Ikeda, H., ...

SOx sorption-desorption characteristics by ZrO2-based mixed oxides (2004)

Kikuyama, S, Miura, A, Kikuchi, R, Takeguchi, T, Eguchi, K

Effect of preparation conditions on platinum metal dispersion and turnover frequency of several reactions over platinum-supported on alumina catalysts (2004)

Matsuhashi, H, Nishiyama, S, Miura, H, Eguchi, K, Hasegawa, K, Iizuka, Y, ...

Characteristics of anodic polarization of solid oxide fuel cells under pressurized conditions (2004)

Kikuchi, R, Yano, T, Takeguchi, T, Eguchi, K

Solid oxide fuel cell as a multi-fuel applicable power generation device (2004)

Kikuchi, R, Eguchi, K

Cytokines regulate fibroblast-like synovial cell differentiation to adipocyte-like cells (2004)

Yamasaki, S., Nakashima, T., Kawakami, A., Miyashita, T., Tanaka, F., Ida, H., ...

Objectives. Our recent work showed that fibroblast-like synovial cells (FLS) could differentiate into adipocyte-like cells in vitro in response to stimulation with peroxisome proliferator-activated...

A novel mutation (T61I) in the gene encoding tumour necrosis factor receptor superfamily 1A (TNFRSF1A) in a Japanese patient with tumour necrosis factor receptor-associated periodic syndrome (TRAPS) associated with systemic lupus erythematosus (2004)

Ida, H., Kawasaki, E., Miyashita, T., Tanaka, F., Kamachi, M., Izumi, Y., ...

Objective. To identify potential mutations in the tumour necrosis factor receptor superfamily 1A gene (TNFRSF1A) in a Japanese female patient with recurrent fever complicated by systemic lupus...

Cytokines regulate fibroblast-like synovial cell differentiation to adipocyte-like cells (2004)

Yamasaki, S., Nakashima, T., Kawakami, A., Miyashita, T., Tanaka, F., Ida, H., ...

Objectives. Our recent work showed that fibroblast-like synovial cells (FLS) could differentiate into adipocyte-like cells in vitro in response to stimulation with peroxisome proliferator-activated...

A novel mutation (T61I) in the gene encoding tumour necrosis factor receptor superfamily 1A (TNFRSF1A) in a Japanese patient with tumour necrosis factor receptor-associated periodic syndrome (TRAPS) associated with systemic lupus erythematosus (2004)

Ida, H., Kawasaki, E., Miyashita, T., Tanaka, F., Kamachi, M., Izumi, Y., ...

Objective. To identify potential mutations in the tumour necrosis factor receptor superfamily 1A gene (TNFRSF1A) in a Japanese female patient with recurrent fever complicated by systemic lupus...

Cytokines regulate fibroblast-like synovial cell differentiation to adipocyte-like cells (2004)

Yamasaki, S., Nakashima, T., Kawakami, A., Miyashita, T., Tanaka, F., Ida, H., ...

Objectives. Our recent work showed that fibroblast-like synovial cells (FLS) could differentiate into adipocyte-like cells in vitro in response to stimulation with peroxisome proliferator-activated...

A novel mutation (T61I) in the gene encoding tumour necrosis factor receptor superfamily 1A (TNFRSF1A) in a Japanese patient with tumour necrosis factor receptor-associated periodic syndrome (TRAPS) associated with systemic lupus erythematosus (2004)

Ida, H., Kawasaki, E., Miyashita, T., Tanaka, F., Kamachi, M., Izumi, Y., ...

Objective. To identify potential mutations in the tumour necrosis factor receptor superfamily 1A gene (TNFRSF1A) in a Japanese female patient with recurrent fever complicated by systemic lupus...

Catalytic activity of oxide-supported Pd catalysts on a honeycomb for low-temperature methane oxidation (2003)

Kikuchi, R, Maeda, S, Sasaki, K, Wennerstrom, S, Ozawa, Y, Eguchi, K

Effect of precious metal addition to Ni-YSZ cermet on reforming of CH4 and electrochemical activity as SOFC anode (2003)

Takeguchi, T, Kikuchi, R, Yano, T, Eguchi, K, Murata, K

Protonic conduction of CsH2PO4 and its composite with silica in dry and humid atmospheres (2003)

Otomo, J, Minagawa, N, Wen, CJ, Eguchi, K, Takahashi, H

Autothermal reforming of methane over Ni catalysts supported over CaO-CeO2-ZrO2 solid solution (2003)

Takeguchi, T, Furukawa, SN, Inoue, M, Eguchi, K

High temperature catalytic combustion of methane and propane over hexaaluminate catalysts: NOx emission characteristics (2003)

Kikuchi, R, Tanaka, Y, Sasaki, K, Eguchi, K

Catalytic combustion of volatile organic compounds on supported precious metal catalysts (2003)

Takeguchi, T, Aoyama, S, Ueda, J, Kikuchi, R, Eguchi, K

Investigation of the interaction between NiO and yttria-stabilized zirconia (YSZ) in the NiO/YSZ composite by temperature-programmed reduction technique (2003)

Mori, H, Wen, CJ, Otomo, J, Eguchi, K, Takahashi, H

Water gas shift reaction of reformed fuel over supported Ru catalysts (2003)

Utaka, T, Okanishi, T, Takeguchi, T, Kikuchi, R, Eguchi, K

Partial oxidation of methane over Ni catalysts based on hexaaliminate- or perovskite-type oxides (2003)

Utaka, T, Al-Drees, SA, Ueda, J, Iwasa, Y, Takeguchi, T, Kikuchi, R, ...

Analysis of the anodic reaction mechanism for solid oxide fuel cell using BaCeO3 electrolyte (2003)

Koyama, M, Wen, CJ, Otomo, J, Taniguchi, N, Yamada, K, Eguchi, K, ...

Strong chemical interaction between PdO and SnO2 and the influence on catalytic combustion of methane (2003)

Takeguchi, T, Takeoh, O, Aoyama, S, Ueda, J, Kikuchi, R, Eguchi, K

Water gas shift reaction for the reformed fuels over Cu/MnO catalysts prepared via spinel-type oxide (2003)

Tanaka, Y, Utaka, T, Kikuchi, R, Takeguchi, T, Sasaki, K, Eguchi, K

CO removal from reformed fuel over Cu/ZnO/Al2O3 catalysts prepared by impregnation and coprecipitation methods (2003)

Tanaka, Y, Utaka, T, Kikuchi, R, Sasaki, K, Eguchi, K

NOx sorption-desorption mechanism of ZrO2-based oxide (2003)

Kikuyama, S, Matsukuma, I, Takeguchi, T, Kikuchi, R, Eguchi, K, Sasaki, K

Catalytic autothermal reforming of methane and propane over supported metal catalysts (2003)

Ayabe, S, Omoto, H, Utaka, T, Kikuchi, R, Sasaki, K, Teraoka, Y, ...

Water gas shift reaction over Cu-based mixed oxides for CO removal from the reformed fuels (2003)

Tanaka, Y, Utaka, T, Kikuchi, R, Sasaki, K, Eguchi, K

CO removal from reformed fuels over Cu and precious metal catalysts (2003)

Utaka, T, Takeguchi, T, Kikuchi, R, Eguchi, K

Fuel flexibility in power generation by solid oxide fuel cells (2002)

Eguchi, K, Kojo, H, Takeguchi, T, Kikuchi, R, Sasaki, K

Steam reforming of methanol on copper catalysts supported on large-surface-area ZnAl2O3 (2002)

Takeguchi, T, Kani, Y, Inoue, M, Eguchi, K

Study on steam reforming of CH4 and C-2 hydrocarbons and carbon deposition on Ni-YSZ cermets (2002)

Takeguchi, T, Kani, Y, Yano, T, Kikuchi, R, Eguchi, K, Tsujimoto, K, ...

Low-temperature methane oxidation over oxide-supported Pd catalysts: inhibitory effect of water vapor (2002)

Kikuchi, R, Maeda, S, Sasaki, K, Wennerstrom, S, Eguchi, K

Current-voltage characteristics and impedance analysis of solid oxide fuel cells for mixed H-2 and CO gases (2002)

Sasaki, K, Hori, Y, Kikuchi, R, Eguchi, K, Ueno, A, Takeuchi, H, ...

A role of components in Pt-ZrO2/Al2O3 as a sorbent for removal of NO and NO2 (2002)

Kikuyama, S, Matsukuma, I, Kikuchi, R, Sasaki, K, Eguchi, K

Catalytically promoted NOx sorption by ZrO2-based oxides (2002)

Eguchi, K, Kikuyama, S

Impedance analysis of electronic transport in dye-sensitized solar cells (2002)

Hoshikawa, T, Kikuchi, R, Sasaki, K, Eguchi, K

Direct-alcohol/hydrocarbon SOFCs: Comparison of power generation characteristics for various fuels (2002)

Sasaki, K, Kojo, H, Hori, Y, Kikuchi, R, Eguchi, K

Development of zirconia-based oxide sorbents for removal of NO and NO2 (2002)

Matsukuma, I, Kikuyama, S, Kikuchi, R, Sasaki, K, Eguchi, K

Thick-film coating of hexaaluminate catalyst on ceramic substrates and its catalytic activity for high-temperature methane combustion (2001)

Kikuchi, R, Takeda, K, Sekizawa, K, Sasaki, K, Eguchi, K

Low temperature oxidation of methane over Pd-based catalysts - effect of support oxide on the combustion activity (2001)

Eguchi, K, Arai, H

Effect of preparation methods on NOx removal ability by sorption in Pt-ZrO2-Al2O3 (2001)

Kikuyama, S, Matsukuma, I, Kikuchi, R, Sasaki, K, Eguchi, K

Elevated serum cytokine levels in a rheumatoid arthritis patient with large granular lymphocyte syndrome (2001)

Ozaki, M., Kawabe, Y., Nakamura, H., Migita, K., Kawakami, A., Tsukazaki, K., ...

Long-standing and intractable ascites involved in renal vein thrombosis of a patient with systemic lupus erythematosus (2000)

YAMASAKI, S., KAWABE, Y., NAKAMURA, H., ISHIKAWA, H., KAWAKAMI, A., MIGITA, K., ...

Evaluation of filtration leucocytapheresis for use in the treatment of patients with rheumatoid arthritis (2000)

Ueki, Y., Yamasaki, S., Kanamoto, Y., Kawazu, T., Yano, M., Matsumoto, K., ...

Objectives. To evaluate the efficacy of filtration leucocytapheresis (LCP) for rheumatoid arthritis (RA). Methods. LCP was carried out three times, with 1 week separating each...

Sjogren's syndrome complicated by MPO-ANCA positive crescentic glomerulonephritis (1999)

Kamachi, M, Migita, K, Tominaga, M, Ichinose, Y, Nakamura, H, Origuchi, T, ...

Preparation of Ultrafine Silicon Nitride, and Silicon Nitride and Silicon Carbide Mixed Powders in a Hybrid Plasma. (1998)

Lee, H. J., Eguchi, K., Yoshida, T.

Ultrafine Si3N4 and Si3N4 + SiC mixed powders were synthesized through thermal plasma chemical vapor deposition (CVD) using a hybrid plasma which was characterized by the superposition of a...

Research is long, life is short (1998)

Eguchi, K

Guidelines for telling the truth to cancer patients. Japanese National Cancer Center (1998)

Okamura, H, Uchitomi, Y, Sasako, M, Eguchi, K, Kakizoe, T

Retrospective analysis of the treatment of patients with small cell lung cancer showing poor performance status (1996)

Sakuragi, T, Oshita, F, Nagashima, S, Kasai, T, Kurata, T, Fukuda, M, ...

Intensive chemotherapy with cisplatin, doxorubicin, cyclophosphamide, etoposide and granulocyte colony-stimulating factor for advanced thymoma or thymic cancer: preliminary results (1995)

Oshita, F, Kasai, T, Kurata, T, Fukuda, M, Yamamoto, N, Ohe, Y, ...

Preliminary evaluation of the new tumor marker, CYFRA 21-1, in lung cancer patients (1994)

Koga, H, Eguchi, K, Shinkai, T, Tamura, T, Ohe, Y, Oshita, F, ...

Chemotherapy-induced anemia in patients with primary lung cancer (1992)

Okamoto, H., Saijo, N., Shinkai, T., Eguchi, K., Sasaki, Y., Tamura, T., ...

To elucidate the factors which influence the value of hemoglobin, the nadir value of hemoglobin, frequency of blood transfusion and prognostic value of blood transfusion in patients with primary lung...

FK506 augments activation-induced programmed cell death of T lymphocytes in vivo.

Migita, K, Eguchi, K, Kawabe, Y, Tsukada, T, Mizokami, A, Nagataki, S

FK506 is an immunosuppressive drug that inhibits T cell receptor-mediated signal transduction. This drug can induce immunological tolerance in allograft recipients. In this study, we investigated the...

Infection of human synovial cells by human T cell lymphotropic virus type I. Proliferation and granulocyte/macrophage colony-stimulating factor production by synovial cells.

Sakai, M, Eguchi, K, Terada, K, Nakashima, M, Yamashita, I, Ida, H, ...

The present study was performed to clarify the relationship between human T cell lymphotropic virus type I (HTLV-I) infection and chronic inflammatory arthropathy. To determine the ability of HTLV-I...

Granulocyte colony-stimulating factor does not enhance phagocytosis or microbicidal activity of human mature polymorphonuclear neutrophils in vitro.

Shimono, N, Okada, K, Takeda, D, Eguchi, K, Misumi, H, Sawae, Y, ...

The direct effects of human granulocyte colony-stimulating factor (hG-CSF) on mature polymorphonuclear neutrophils (PMNs) in vitro were studied with regard to chemotaxis, superoxide production, and...

FK506 augments activation-induced programmed cell death of T lymphocytes in vivo.

Migita, K, Eguchi, K, Kawabe, Y, Tsukada, T, Mizokami, A, Nagataki, S

FK506 is an immunosuppressive drug that inhibits T cell receptor-mediated signal transduction. This drug can induce immunological tolerance in allograft recipients. In this study, we investigated the...

Infection of human synovial cells by human T cell lymphotropic virus type I. Proliferation and granulocyte/macrophage colony-stimulating factor production by synovial cells.

Sakai, M, Eguchi, K, Terada, K, Nakashima, M, Yamashita, I, Ida, H, ...

The present study was performed to clarify the relationship between human T cell lymphotropic virus type I (HTLV-I) infection and chronic inflammatory arthropathy. To determine the ability of HTLV-I...

Granulocyte colony-stimulating factor does not enhance phagocytosis or microbicidal activity of human mature polymorphonuclear neutrophils in vitro.

Shimono, N, Okada, K, Takeda, D, Eguchi, K, Misumi, H, Sawae, Y, ...

The direct effects of human granulocyte colony-stimulating factor (hG-CSF) on mature polymorphonuclear neutrophils (PMNs) in vitro were studied with regard to chemotaxis, superoxide production, and...

Inhibitory effects of interleukin-10 on synovial cells of rheumatoid arthritis.

Kawakami, A, Eguchi, K, Matsuoka, N, Tsuboi, M, Urayama, S, Kawabe, Y, ...

This paper describes the immunoregulatory effects of interleukin-10 (IL-10) on synovial cells in vitro. Synovial cells were cultured with IL-10 in the presence or absence of various cytokines....

CD4+ T-cell-mediated cytotoxicity against staphylococcal enterotoxin B-pulsed synovial cells.

Kawakami, A, Matsuoka, N, Tsuboi, M, Urayama, S, Nakashima, T, Kawabe, Y, ...

Apoptosis of synovial cells in rheumatoid arthritis (RA) synovium determined in vivo is suggested to counteract the overgrowth of synovium. Immunohistological examination has revealed the...

Tyrosine phosphorylation participates in peripheral T-cell activation and programmed cell death in vivo.

Migita, K, Eguchi, K, Kawabe, Y, Nagataki, S

T-cell antigen receptor (TCR), which is not itself a protein tyrosine kinase (PTK), is thought to be associated with at least two SRC-like PTKs, P59fyn and ZAP-70. Activation of these PTKs is...

Detection of Leu-19 (CD56) antigen on human thyroid epithelial cells by an immunohistochemical method.

Migita, K, Eguchi, K, Kawakami, A, Ida, H, Fukuda, T, Kurata, A, ...

The Leu-19 (CD56) antigen, which is recognized by anti-Leu-19 and NKH-1 monoclonal antibody, is a 200,000-220,000 molecular weight (MW) glycoprotein that is expressed predominantly on human natural...

Hereditary deficiency of OKT4-positive cells: studies for mode of inheritance and lymphocyte functions.

Fukuda, T, Matsunaga, M, Kurata, A, Mine, M, Ikari, N, Katamine, S, ...

Two Graves' patients were found to have no OKT4+ cells in their peripheral blood lymphocytes (PBL). However, the reactivity of their lymphocytes with T4(T4A) and anti Leu-3a was normal and no...

Staphylococcal enterotoxin B-specific adhesion of murine splenic T cells to a human endothelial cell line.

Kita, M, Eguchi, K, Kawabe, Y, Tsukada, T, Migita, K, Kawakami, A, ...

The presence of a putative autoantigen of autoimmune disorder in a target organ may cause accumulation of specific T cells in the inflammatory region. One of the mechanisms of such accumulation...

TNF-alpha-mediated expression of membrane-type matrix metalloproteinase in rheumatoid synovial fibroblasts.

Migita, K, Eguchi, K, Kawabe, Y, Ichinose, Y, Tsukada, T, Aoyagi, T, ...

Degradation of the extracellular matrix plays an important role in rheumatoid articular destruction. Rheumatoid synovial fibroblasts secrete a large amount of matrix-degrading metalloproteinases...

Primary Sjögren's syndrome with antibodies to HTLV-I: clinical and laboratory features.

Eguchi, K, Matsuoka, N, Ida, H, Nakashima, M, Sakai, M, Sakito, S, ...

The prevalence of antibodies to human T lymphotropic virus type I (HTLV-I) was studied in patients with primary Sjögren's syndrome. Thirteen of 36 serum samples were positive by enzyme linked...

Expression of basic fibroblast growth factor in synovial tissues from patients with rheumatoid arthritis: detection by immunohistological staining and in situ hybridisation.

Nakashima, M, Eguchi, K, Aoyagi, T, Yamashita, I, Ida, H, Sakai, M, ...

OBJECTIVE--The distribution and production of basic fibroblast growth factor (bFGF) was examined on the synovium from patients with rheumatoid arthritis (RA) and osteoarthritis (OA). METHODS--The...

Treatment of patients with polyarthritis and anti-HTLV-I antibodies with interferon-alpha.

Aoyagi, T, Maeda, K, Furuichi, I, Eguchi, K, Sakai, M, Nagataki, S, ...

Interleukin 4 increases human synovial cell expression of VCAM-1 and T cell binding.

Shimada, H, Eguchi, K, Ueki, Y, Nakashima, M, Yamashita, I, Kawabe, Y, ...

OBJECTIVE--The effects were studied of interleukin 4 (IL-4) on T cell-synovial cell adhesion and on the expression of adhesion molecules on the surface of synovial fibroblast-like cells. METHODS--The...

Increment of CD8S6F1 cells in synovial fluid from patients with rheumatoid arthritis.

Ueki, Y, Eguchi, K, Miyake, S, Nagataki, S, Tominaga, Y

OBJECTIVE--To investigate the role of CD8 cell subsets in the pathogenesis of rheumatoid arthritis (RA) and the phenotypes of T cells adherent or non-adherent to the target cells (endothelial cells...

HTLV-I associated arthritis: characteristics of an HTLV-I virus infected T cell line from synovial fluid.

Eguchi, K, Nakamura, T, Mine, M, Ida, H, Kawakami, A, Migita, K, ...

A T cell line from mononuclear cells in the synovial fluid of a patient with polyarthritis was established. The T cell line reacted with serum samples positive for antibodies to human T cell...

Increased levels of serum IgM antibody to staphylococcal enterotoxin B in patients with rheumatoid arthritis.

Origuchi, T, Eguchi, K, Kawabe, Y, Yamashita, I, Mizokami, A, Ida, H, ...

OBJECTIVE--To investigate the role of superantigen in rheumatoid arthritis (RA) by assaying the serum levels of staphylococcal enterotoxin B (SEB) antibodies. METHODS--Serum IgG and IgM SEB...

Cytokine production by endothelial cells infected with human T cell lymphotropic virus type I.

Takashima, H, Eguchi, K, Kawakami, A, Kawabe, Y, Migita, K, Sakai, M, ...

OBJECTIVE: To investigate the ability of human T cell lymphotropic virus type I (HTLV-I) to infect endothelial cells and induce cytokine production by these cells. METHODS: Human umbilical vein...

High prevalence of Sjögren's syndrome in patients with HTLV-I associated myelopathy

Nakamura, H., Eguchi, K., Nakamura, T., Mizokami, A., Shirabe, S., Kawakami, A., ...

OBJECTIVE—A high seroprevalence of HTLV-I in female Sjögren's syndrome (SS) patients has been reported in Nagasaki, Japan, an area that is heavily endemic for HTLV-I infection. Salivary IgA class...

Corticosteroid irrigation of parotid gland for treatment of xerostomia in patients with Sjögren's syndrome

Izumi, M., Eguchi, K., Nakamura, H., Takagi, Y., Kawabe, Y., Nakamura, T.

OBJECTIVE—To determine the efficacy of corticosteroid irrigation of the parotid gland in relieving salivary flow deficiency in patients with Sjögren's syndrome.
METHODS—The parotid glands of...

HTLV-I associated Sjögren's syndrome is aetiologically distinct from anti-centromere antibodies positive Sjögren's syndrome

Hida, A., Kawabe, Y., Kawakami, A., Migita, K., Tominaga, M., Nakamura, H., ...

OBJECTIVE—To investigate whether Sjögren's syndrome (SS) with anti-HTLV-I antibodies is aetiopathologically distinguishable from SS without these antibodies, the study compared prevalence of...

Expression of mitogen activated protein kinases in labial salivary glands of patients with Sjögren's syndrome

Nakamura, H., Kawakami, A., Yamasaki, S., Kawabe, Y., Nakamura, T., Eguchi, K.

OBJECTIVE—The expression of CD40 and CD40 ligand (CD40L) in mononuclear cells (MNCs) infiltrating the salivary glands of patients with Sjögren's syndrome (SS) has recently been reported. This...

Polyarteritis nodosa complicated by thrombotic thrombocytopenic purpura

YAMASAKI, S, TOMINAGA, M, KAWAKAMI, A, MIGITA, K, KAWABE, Y, IZUMINO, K, ...

Importance of NF-κB in rheumatoid synovial tissues: in situ NF-κB expression and in vitro study using cultured synovial cells

Yamasaki, S, Kawakami, A, Nakashima, T, Nakamura, H, Kamachi, M, Honda, S, ...

OBJECTIVES—To examine whether inhibition of NF-κB induces apoptosis of human synovial cells stimulated by tumour necrosis factor α (TNFα), interleukin 1β (IL1β), and anti-Fas monoclonal...

Sonography as a replacement for sialography for the diagnosis of salivary glands affected by Sjögren's syndrome

Yonetsu, K, Takagi, Y, Sumi, M, Nakamura, T, Eguchi, K

Correlation between interleukin 10 gene promoter region polymorphisms and clinical manifestations in Japanese patients with Sjögren's syndrome

Origuchi, T, Kawasaki, E, Ide, A, Kamachi, M, Tanaka, F, Ida, H, ...

Anti-apoptogenic function of TGFß1 for human synovial cells: TGFß1 protects cultured synovial cells from mitochondrial perturbation induced by several apoptogenic stimuli

Kawakami, A, Urayama, S, Yamasaki, S, Hida, A, Miyashita, T, Kamachi, M, ...

Methods: Isolated synovial cells, treated or not with TGFß1, were cultured in the presence or absence of anti-Fas IgM, proteasome inhibitor Z-Leu-Leu-Leu-aldehyde (LLL-CHO), etoposide, or...

Non-alcoholic steatohepatitis and hepatic steatosis in patients with adult onset growth hormone deficiency

Ichikawa, T, Hamasaki, K, Ishikawa, H, Ejima, E, Eguchi, K, Nakao, K

Bone marrow engraftment in a rodent model of chemical carcinogenesis but no role in the histogenesis of hepatocellular carcinoma

Ishikawa, H, Nakao, K, Matsumoto, K, Nishimura, D, Ichikawa, T, Hamasaki, K, ...

Background and aim: Recent studies indicated that hepatic stem cells in the bone marrow could differentiate into mature hepatocytes, suggesting that bone marrow cells could be used for replacement of...

Immunofluorescent studies on S-protein in glomeruli from patients with IgA nephropathy.

Tomino, Y., Yagame, M., Eguchi, K., Nomoto, Y., Sakai, H.

Detection of S-protein, which is a regulatory component of the membrane attack complex (MAC), and of C9 in glomeruli by immunofluorescence in 11 of 15 patients with IgA nephropathy is described. The...

Comparative study of intraoperative mitomycin C and β irradiation in pterygium surgery

Amano, S., Motoyama, Y., Oshika, T., Eguchi, S., Eguchi, K.

AIMS—To compare the rate of recurrence and complication after surgery for primary pterygium performed by one surgeon using either intraoperative mitomycin C or β irradiation.
METHODS—A...

Synovial cells are potent antigen-presenting cells for superantigen, staphylococcal enterotoxin B (SEB).

Origuchi, T, Eguchi, K, Kawabe, Y, Mizokami, A, Ida, H, Nagataki, S

There is ample evidence suggesting that superantigens may act as a triggering factor in the pathogenesis of rheumatoid arthritis (RA). We investigated whether superantigen could activate T cells in...

Expression of adhesion molecules on infiltrating T cells in thyroid glands from patients with Graves' disease.

Ishikawa, N, Eguchi, K, Ueki, Y, Nakashima, M, Shimada, H, Ito, K, ...

The present study was performed to elucidate the role of adhesion molecules in the pathogenesis of Graves' disease. Peripheral blood and intrathyroidal mononuclear cells were obtained from 14...

Rheumatoid factor and glomerulonephritis

Miyazaki, M., Endoh, M., Suga, T., Yano, N., Kuramoto, T., Matsumoto, Y., ...

It is presently unknown whether rheumatoid factors have a pathogenic role in the development of various types of glomerulonephritis with immune deposits. Three isotypes of rheumatoid factors (RFs),...

Cytokine regulation of HLA on thyroid epithelial cells

Migita, K., Eguchi, K., Otsubo, T., Kawakami, A., Nakao, H., Ueki, Y., ...

The regulation of class I and class II HLA expression in human thyroid follicular cells was studied in vitro. Tumour necrosis factor-alpha (TNF-α) enhanced the expression of class I antigen on...

Synergy in antigen presentation by thyroid epithelial cells and monocytes from patients with graves' disease

Eguchi, K., Otsubo, T., Kawabe, Y., Shimomura, Chikako, Ueki, Y., Nakao, H., ...

The present study was undertaken to examine the ability of thyrocytes from Graves' patients to present purified protein derivative (PPD) to autologous peripheral blood T cells. Normal human...

Cytotoxic activity of interleukin-2 (IL-2) activated killer cells toward thyroid epithelial cells

Migita, K., Eguchi, K., Tezuka, H., Otsubo, T., Kawakami, A., Nakao, H., ...

We investigated the sensitivity of thyroid epithelial cells (thyrocytes) to IL-2 activated killer cells. The thyrocytes were lysed by autologous and allogeneic IL-2-activated killer cells; there were...

The remarkable proliferation of helper T cell subset in response to autologous thyrocytes and intrathyroidal T cells from patients with graves' disease

Eguchi, K., Otsubo, T., Kawabe, Y., Ueki, Y., Fukuda, T., Matsunaga, Mayumi, ...

We have studied cellular interactions among thyrocytes, intrathyroidal T cells and peripheral blood T cells from Graves' patients. In the autologous mixed lymphocyte reaction of Graves' patients,...

Interferon-alpha and dexamethasone inhibit adhesion of T cells to endothelial cells and synovial cells

Eguchi, K., Kawakami, A., Nakashima, M., Ida, H., Sakito, S., Matsuoka, N., ...

We investigated whether interferon-gamma (IFN-γ), interferon-alpha (IFN-α) and glucocorticoids affected the adhesion of T cells to human umbilical endothelial cells or human synovial cells. About...

Production of a monoclonal antibody to a membrane antigen of human T-cell leukaemia virus (HTLV1/ATLV)-infected cell lines from a systemic lupus erythematosus (SLE) patient: serological analyses for HTLV1 infections in SLE patients.

Kurata, A, Katamine, S, Fukuda, T, Mine, M, Ikari, N, Kanazawa, H, ...

Human T-cell leukaemia virus (HTLV1/ATLV), which causes adult T cell leukaemia (ATL), is an infectious, lymphotrophic retrovirus unique for humans. The present study was undertaken to determine...

Th1 and Th1-inducing cytokines in Salmonella infection

MIZUNO, Y, TAKADA, H, NOMURA, A, JIN, C-H, HATTORI, H, IHARA, K, ...

Thl and Thl-inducing cytokines and T cell responses were investigated in human salmonellosis. Serum IFN-γ, IL-12 and IL-18 levels were increased significantly in patients with salmonellosis. The...

Dendritic cells infected with adenovirus expressing the thyrotrophin receptor induce Graves’ hyperthyroidism in BALB/c mice

KITA-FURUYAMA, M, NAGAYAMA, Y, PICHURIN, P, MCLACHLAN, S M, RAPOPORT, B, EGUCHI, K

Dendritic cells (DCs) are the most potent antigen-presenting cells and a prerequisite for the initiation of primary immune response. This study was performed to investigate the contribution of DCs to...

Osteoprotegerin (OPG) acts as an endogenous decoy receptor in tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis of fibroblast-like synovial cells

Miyashita, T, Kawakami, A, Nakashima, T, Yamasaki, S, Tamai, M, Tanaka, F, ...

We examined the role of osteoprotegerin (OPG) on tumour necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in rheumatoid fibroblast-like synovial cells (FLS). OPG protein...

Suppressive effect of leflunomide metabolite (A77 1726) on metalloproteinase production in IL-1β stimulated rheumatoid synovial fibroblasts

MIGITA, K, MIYASHITA, T, ISHIBASHI, H, MAEDA, Y, NAKAMURA, M, YATSUHASHI, H, ...

Leflunomide, an isoxazol derivative structurally unrelated to other immunomodulatory drugs, has proven to be efficacious in the treatment of rheumatoid arthritis (RA). This study was conducted to...

Reduced blood BDCA-2+ (lymphoid) and CD11c+ (myeloid) dendritic cells in systemic lupus erythematosus

Migita, K, Miyashita, T, Maeda, Y, Kimura, H, Nakamura, M, Yatsuhashi, H, ...

Type 1 IFN is thought to be implicated in the autoimmune process of SLE. Plasmacytoid dendric cells (DC), which are natural IFN-α producing cells, play a pivotal epipathogenic role in SLE. The...

Detection of apoptosis-specific autoantibodies directed against granzyme B-induced cleavage fragments of the SS-B (La) autoantigen in sera from patients with primary Sjögren's syndrome

Huang, M, Ida, H, Kamachi, M, Iwanaga, N, Izumi, Y, Tanaka, F, ...

The objective of this study was to detect autoantibodies against granzyme B cleavage products in sera from patients with primary Sjögren's syndrome (SS). Cell lysates derived from human salivary...

Effects of rapamycin on apoptosis of rheumatoid synovial cells

MIGITA, K, EGUCHI, K, ICHINOSE, Y, KAWABE, Y, TSUKADA, T, AOYAGI, T, ...

In the present study, we investigated the effects of an immunosuppressant, rapamycin, on bcl-2 expression and the susceptibility of human rheumatoid synovial fibroblasts to Fas-mediated apoptosis....

Modulation of Fas-mediated apoptosis of human thyroid epithelial cells by IgG from patients with Graves' disease (GD) and idiopathic myxoedema

KAWAKAMI, A, EGUCHI, K, MATSUOKA, N, TSUBOI, M, URAYAMA, S, KAWABE, Y, ...

The expression of two autoimmune thyroid diseases, GD and idiopathic myxoedema, is associated with antibodies to the thyroid-stimulating hormone (TSH) receptor. Thyroid stimulating antibodies (TSAb)...

Apoptosis in labial salivary glands from Sjögren's syndrome (SS) patients: comparison with human T lymphotropic virus-I (HTLV-I)-seronegative and -seropositive SS patients

Nakamura, H, Koji, T, Tominaga, M, Kawakami, A, Migita, K, Kawabe, Y, ...

Apoptosis is a type of cell death that occurs during morphogenesis and development of the immune system. One of the mechanisms is mediated through the Fas and Fas ligand (FasL) pathway. To determine...

Expression of cyclooxygenase-1 (COX-1) in labial salivary glands of Sjögren's syndrome

Tominaga, M, Migita, K, Sano, H, Fukui, W, Kohno, M, Tsubouchi, Y, ...

COX plays an important role in inflammatory diseases such as rheumatoid arthritis. To determine the role of COX in Sjögren's syndrome (SS), we examined COX expression in the salivary glands of SS...

Impaired degradation of serum amyloid A (SAA) protein by cytokine-stimulated monocytes

Migita, K, Yamasaki, S, Shibatomi, K, Ida, H, Kita, M, Kawakami, A, ...

Secondary amyloidosis (AA amyloidosis) is a systemic disease characterized by the extracellular tissue deposition of insoluble amyloid A (AA) protein. Aberrant metabolism of serum amyloid A (SAA) by...

Fas/FasL mediated apoptosis of thyrocytes in Graves' disease

Sera, N, Kawakami, A, Nakashima, T, Nakamura, H, Imaizumi, M, Koji, T, ...

We examined in the present study the possible involvement of Fas and its ligand (FasL) in the process of Graves' disease. Immunohistochemical analysis showed that few normal thyrocytes expressed Fas...

Novel immunosuppressive effect of FK506 by augmentation of T cell apoptosis

Hashimoto, Y, Matsuoka, N, Kawakami, A, Tsuboi, M, Nakashima, T, Eguchi, K, ...

We have recently reported the accumulation of oligoclonal activated T cells in the spontaneously developed autoimmune pancreatitis in aly/aly mouse. In this study, we examined the effects of FK506 in...

Expression of membrane-type 1 matrix metalloproteinase in rheumatoid synovial cells

Honda, S, Migita, K, Hirai, Y, Origuchi, T, Yamasaki, S, Kamachi, M, ...

Membrane-type 1 matrix metalloproteinase (MT1-MMP) is thought to be a putative regulator of pro-gelatinase A (MMP-2) in the rheumatoid synovium. In this study, we examined the effects of IL-1β, one...

Regulation of rheumatoid synoviocyte proliferation by endogenous p53 induction

Migita, K, Tanaka, F, Yamasaki, S, Shibatomi, K, Ida, H, Kawakami, A, ...

The p53 tumour suppressor protein protects cells from tumorigenic alterations by inducing either cell growth arrest or apoptosis. In the present study, we investigated the role of endogenous p53...

Functional changes in rheumatoid fibroblast-like synovial cells through activation of peroxisome proliferator-activated receptor γ-mediated signalling pathway

YAMASAKI, S, NAKASHIMA, T, KAWAKAMI, A, MIYASHITA, T, IDA, H, MIGITA, K, ...

Peroxisome proliferator-activated receptor γ (PPARγ) is a ligand dependent transcriptional factor known to be a regulator of adipogenesis. Recent studies have also shown that stimulation of PPARγ...

The effects of the immunosuppressant rapamycin on the growth of rheumatoid arthritis (RA) synovial fibroblast

MIGITA, K, EGUCHI, K, AOYAGI, T, TSUKADA, T, TSUBOI, M, KAWABE, Y, ...

RA is a chronic inflammatory disease characterized by mononuclear cell infiltration and the overgrowth of synovial fibroblast. This invasive growth of synovial tissues corresponds with the...

Inhibitory effect of clarithromycin on costimulatory molecule expression and cytokine production by synovial fibroblast-like cells

MATSUOKA, N, EGUCHI, K, KAWAKAMI, A, TSUBOI, M, KAWABE, Y, AOYAGI, T, ...

This study was undertaken to investigate the immunomodulatory effect of clarithromycin against synovial fibroblast-like cells (synoviocytes). Synovial tissue obtained from rheumatoid arthritis (RA)...

Nuclear factor‐κB and caspases co‐operatively regulate the activation and apoptosis of human macrophages

Hida, A, Kawakami, A, Nakashima, T, Yamasaki, S, Sakai, H, Urayama, S, ...

Accumulating evidence suggests that macrophages function as major effector cells in the pathological process of various human diseases. We examined here the role of nuclear factor‐κB (NF‐κB)...

RS3PE syndrome presenting as vascular endothelial growth factor associated disorder

Arima, K, Origuchi, T, Tamai, M, Iwanaga, N, Izumi, Y, Huang, M, ...

Methods: Vascular endothelial growth factor165 (VEGF165), tumour necrosis factor α (TNFα), and interleukin 1ß (IL1ß) were measured by enzyme linked immunosorbent assay (ELISA) in serum samples...

The presence of anti‐cyclic citrullinated peptide antibody is associated with magnetic resonance imaging detection of bone marrow oedema in early stage rheumatoid arthritis

Tamai, M, Kawakami, A, Uetani, M, Takao, S, Tanaka, F, Nakamura, H, ...

Early prediction of rheumatoid arthritis by serological variables and magnetic resonance imaging of the wrists and finger joints: results from prospective clinical examination

Tamai*, M, Kawakami*, A, Uetani, M, Takao, S, Rashid, H, Tanaka, F, ...

Effect of chemotherapy on natural-killer activity and antibody-dependent cell-mediated cytotoxicity in carcinoma of the lung.

Saijo, N., Shimizu, E., Shibuya, M., Irimajiri, N., Takizawa, T., Eguchi, K., ...

The effect of chemotherapy on natural killer (NK) activity and antibody-dependent cell-mediated cytotoxicity (ADCC) in 15 advanced carcinomas of the lung was examined with regard to the drug, dose,...

Measurement and evaluation of serum anti-p53 antibody levels in patients with lung cancer at its initial presentation: a prospective study.

Segawa, Y., Kageyama, M., Suzuki, S., Jinno, K., Takigawa, N., Fujimoto, N., ...

Anti-p53 antibodies in sera are known to be products of the host immune response to mutated p53 protein, and are present in some patients with various types of cancer. In this study, we measured...

Granulocyte colony-stimulating factor receptor expression on human transitional cell carcinoma of the bladder.

Tachibana, M., Miyakawa, A., Uchida, A., Murai, M., Eguchi, K., Nakamura, K., ...

Receptors for granulocyte colony-stimulating factor (G-CSFRs) have been confirmed on the cell surfaces of several non-haematopoietic cell types, including bladder cancer cells. This observation has...

Phase I study of sequentially administered topoisomerase I inhibitor (irinotecan) and topoisomerase II inhibitor (etoposide) for metastatic non-small-cell lung cancer.

Ando, M., Eguchi, K., Shinkai, T., Tamura, T., Ohe, Y., Yamamoto, N., ...

We conducted a phase I study of irinotecan (CPT-11) and etoposide (VP-16) given sequentially to untreated patients with metastatic non-small-cell lung cancer. Arm A: CPT-11 was given over 90 min on...

A phase II study of cisplatin and 5-fluorouracil with concurrent hyperfractionated thoracic radiation for locally advanced non-small-cell lung cancer: a preliminary report from the Okayama Lung Cancer Study Group

Segawa, Y, Ueoka, H, Kiura, K, Kamei, H, Tabata, M, Sakae, K, ...

A recent meta-analysis and randomized studies have demonstrated that combined chemoradiotherapy is associated with a survival advantage for selected patients with locally advanced unresectable...

Fractionated administration of irinotecan and cisplatin for treatment of non-small-cell lung cancer: a phase II study of Okayama Lung Cancer Study Group

Ueoka, H, Tanimoto, M, Kiura, K, Tabata, M, Takigawa, N, Segawa, Y, ...

A phase II study of fractionated administration of irinotecan (CPT-11) and cisplatin (CDDP) in patients with non-small-cell lung cancer (NSCLC) was conducted. Between January 1996 and January 1998,...

Phase I/II trial of weekly cisplatin, etoposide, and irinotecan chemotherapy for metastatic lung cancer: JCOG 9507

Sekine, I, Nishiwaki, Y, Kakinuma, R, Kubota, K, Hojo, F, Matsumoto, T, ...

Phase I/II study of docetaxel and cisplatin with concurrent thoracic radiation therapy for locally advanced non-small-cell lung cancer

Kiura, K, Ueoka, H, Segawa, Y, Tabata, M, Kamei, H, Takigawa, N, ...