K. Hoshino

Details der Publikationsliste

Zeitraum

1980 - 2009

Anzahl

145

Co-Autoren

Final tau-neutrino results from the DONuTexperiment (2008)

Kodama, K., Ushida, N., Andreopoulos, C., Saoulidou, N., Tzanakos, G., Yager, P., ...

The DONuT experiment collected data in 1997 and published first results in 2000 based on four observedν_τ charged-current (CC) interactions. The final analysis of the data collected in the...

Leading order analysis of neutrino induced dimuon events in the CHORUS experiment (2008)

Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Oldeman, R G C, Güler, M, ...

We present a leading order QCD analysis of a sample of neutrino induced charged-current events with two muons in the final state originating in the lead-scintillating fibre calorimeter of the CHORUS...

Associated Charm Production in Neutrino-Nucleus Interactions (2008)

Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Oldeman, R G C, Güler, M, ...

In this paper a search for associated charm production both in neutral and charged current $\nu$-nucleus interactions is presented. The improvement of automatic scanning systems in the \mbox{CHORUS}...

Final results on $\nu_{\mu} \to \nu_{\tau}$ oscillation from the CHORUS experiment (2007)

Eskut, E, Kayis-Topaksu, A, Onengüt, G, Van Beuzekom, M G, Van Dantzig, R, De Jong, M, ...

The final oscillation analysis of the complete set of data collected by CHORUS in the years 1994-1997 is presented. Reconstruction algorithms of data extracted by electronic detectors were improved...

Charged-Particle Multiplicities in Charged-Current Neutrino-and Anti-Neutrino-Nucleus Interactions (2007)

Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Oldeman, R G C, Güler, M, ...

The CHORUS experiment, designed to search for $\nu_{\mu}\->\nu_{\tau}$ oscillations, consists of a nuclear emulsion target and electronic detectors. In this paper, results on the production of...

Associated Charm Production in Neutrino-Nucleus Interactions (2007)

Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Oldeman, R G C, Güler, M, ...

In this paper a search for associated charm production both in neutral and charged current $\nu$-nucleus interactions is presented. The improvement of automatic scanning systems in the {CHORUS}...

Charged-Particle Multiplicities in Charged-Current Neutrino-and Anti-Neutrino-Nucleus Interactions (2007)

Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Oldeman, R G C, Güler, M, ...

The CHORUS experiment, designed to search for $\nu_{\mu}\to\nu_{\tau}$ oscillations, consists of a nuclear emulsion target and electronic detectors. In this paper, results on the production of...

Double-sided scanning micromirror array for autostereoscopic display (2007)

Nakai, A, Hoshino, K, Matsumoto, K, Shimoyama, I

This paper reports a double-sided scanning micromirror array for an autostereoscopic display. Double-sided micromirrors actuated by both external magnetic force and Lorentz force were designed and...

First events from the CNGS neutrino beam detected in the OPERA experiment (2007)

Acquafredda, R., Agafonova, N., Ambrosio, M., Anokhina, A., Aoki, S., Ariga, A., ...

The OPERA neutrino detector at the underground Gran Sasso Laboratory (LNGS) was designed to perform the first detection of neutrino oscillations in appearance mode, through the study of nu_mu to...

Selection of environmental temperature by the yellow scorpion Tityus serrulatus Lutz & Mello, 1922 (Scorpiones, Buthidae) (2006)

Hoshino,K., Moura,A. T. V.

The preferred temperature of the yellow scorpion Tityus serrulatus was investigated since its dispersion is a matter of concern. Adult T. serrulatus, weighing 1.24 + 0.20 g (mean + sd) and with a...

Measurement of Nucleon Structure Functions in Neutrino Scattering (2005)

Önengüt, G, Van Dantzig, R, De Jong, M, Oldeman, R G C, Güler, M, Kama, S, ...

After completion of the data taking for the $\nu_\mu\to\nu_\tau$ oscillation search, the CHORUS lead--scintillator calorimeter was used in the 1998 run as an active target. High-statistics samples of...

Measurement of topological muonic branching ratios of charmed hadrons produced in neutrino-induced charged-current interactions (2005)

Kayis-Topaksu, A, Önengüt, G, Van Dantzig, R, De Jong, M, Oldeman, R G C, Güler, M, ...

From 1994 to 1997, the emulsion target of the CHORUS detector was exposed to the wideband neutrino beam of the CERN SPS. In total about 100 000 charged-current neutrino interactions were located in...

Search for Superfragments and Measurement of the Production of Hyperfragments in Neutrino-Nucleus Interactions (2005)

Onengüt, G, Van Dantzig, R, De Jong, M, Oldeman, R G C, Güler, M, Köse, U, ...

A systematic search for superfragments (charmed nuclei) has been performed in 22 200 neutrinoâ€"emulsion interactions obtained with the CHORUS experiment making use of automatic off-line image...

Measurements of $D^0$ production and of decay branching fractions in neutrino nucleon scattering (2005)

Önengüt, G, Van Dantzig, R, De Jong, M, Oldeman, R G C, Güler, M, Köse, U, ...

During the years 1994-97, the emulsion target of the CHORUS detector was exposed to the wide-band neutrino beam of the CERN SPS of 27 GeV average neutrino energy. In total about 100 000...

Measurement of $D^{*+}$ production in charged-current neutrino interactions (2005)

Önengüt, G, Van Dantzig, R, De Jong, M, Oldeman, R G C, Güler, M, Köse, U, ...

During the years 1994-97, the emulsion target of the CHORUS detector was exposed to the wide-band neutrino beam of the CERN SPS of 27 GeV average neutrino energy. In total about 100 000...

Measurement of fragmentation properties of charmed particle production in charged-current neutrino interactions (2005)

Onengüt, G, Van Dantzig, R, De Jong, M, Konijn, J, Melzer, O, Oldeman, R G C, ...

During the years 1994-97, the emulsion target of the CHORUS detector was exposed to the wideband neutrino beam of the CERN SPS. In total about 100 000 charged-current neutrino interactions were...

Measurement of charm production in antineutrino charged-current interactions (2005)

Onengüt, G, Van Dantzig, R, De Jong, M, Konijn, J, Melzer, O, Oldeman, R G C, ...

During the years 1994-97, the emulsion target of the CHORUS detector was exposed to the wideband neutrino beam of the CERN SPS collecting about 10^6 neutrino interactions. A measurement of...

Optical diffraction spectroscopy of excitons in uniaxially-strained GaN films (2004)

Toda, Y., Adachi, S., Abe, Y., Hoshino, K., Arakawa, Y.

The degenerate four-wave mixing spectroscopy of uniaxially strained GaN layers is demonstrated using colinearly polarized laser pulses. The nonlinear response of FWM signal on exciton oscillator...

Experimental Study of Trimuon Events in Neutrino Charged-Current Interactions (2004)

Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Konijn, J, Melzer, O, ...

This paper reports on a study of trimuon events induced by neutrino interactions in the CHORUS calorimeter exposed to the CERN SPS wide-band nu_mu beam. Among the multimuon events produced in the...

Experimental Study of Trimuon Events in Neutrino Charged-Current Interactions (2004)

Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Konijn, J, Melzer, O, ...

This paper reports on a study of trimuon events induced by neutrino interactions in the CHORUS calorimeter exposed to the CERN SPS wide-band nu_mu beam. Among the multimuon events produced in the...

The compulsive-like aspect of the head dipping emission in rats with chronic electrolytic lesion in the area of the median raphe nucleus (2004)

Hoshino,K., Uga,D.A.

Head dipping (HD) is a behavioral pattern considered to have a risk assessment or an exploratory role and is used as a complementary parameter to evaluate anxiety in experimental animals. Since rats...

Cross-section measurement for quasi-elastic production of charmed baryons in $\nu N$ interactions (2003)

Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Melzer, O, Oldeman, R G C, ...

A study of quasi-elastic production of charmed baryons in charged-current interactions of neutrinos with the nuclear emulsion target of CHORUS is presented. In a sample of about 46000 interactions...

Measurement of the $Z/A$ dependence of neutrino charged-current total cross-sections (2003)

Kayis-Topaksu, A, Onengüt,G, Van Dantzig, R, De Jong, M, Konijn, J, Melzer, O, ...

A relative measurement of total cross-sections is reported for polyethylene, marble, iron, and lead targets for the inclusive charged-current reaction nu_mu + N -> mu^- + X. The targets, passive...

Measurement of the $Z/A$ dependence of neutrino charged-current total cross-sections (2003)

Kayis-Topaksu, A, Onengüt,G, Van Dantzig, R, De Jong, M, Konijn, J, Melzer, O, ...

A relative measurement of total cross-sections is reported for polyethylene, marble, iron, and lead targets for the inclusive charged-current reaction nu_mu + N -> mu^- + X. The targets, passive...

Measurement of $\Lambda^{+}_{c}$ production in neutrino charged-current interactions (2003)

Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Melzer, O, Oldeman, R G C, ...

A measurement of $\Lambda_c^+$ production in neutrino nucleon charged-current interactions is presented. In a sub-sample of about 50 000 interactions located in the emulsion target of the CHORUS...

High mach flow associated with plasma detachment in JT-60U (2003)

Hatayama,A., Hoshino,K., Miyamoto,K., Komatsu,N., Itami,K., Sakurai,S., ...

Recent new results of the high Mach flows associated with plasma detachment are presented on the basis of numerical simulations and their comparisons with experiments in JT-60U divertor plasma. The...

High mach flow associated with plasma detachment in JT-60U (2003)

Hatayama, A., Hoshino, K., Miyamoto, K., Komatsu, N., Itami, K., Sakurai, S., ...

Recent new results of the high Mach flows associated with plasma detachment are presented on the basis of numerical simulations and their comparisons with experiments in JT-60U divertor plasma. The...

Determination of the semi-leptonic branching fraction of charm hadrons produced in neutrino charged-current interactions (2002)

Kayis-Topaksu, A, Onengüt, G, De Jong, M, Melzer, O, Oldeman, R G C, Pesen, E, ...

During the years 1994--1997, the emulsion target of the CHORUS detector was exposed to the CERN-SPS Wide Band Neutrino Beam. The improvements of the past few years in the automatic emulsion scanning...

Observation of one event with the characteristics of associated charm production in neutrino charged-current interactions (2002)

Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Konijn, J, Melzer, O, ...

We report on a search for associated charm production in neutrino charged-current interactions in the CHORUS experiment, based on the visual observation of charmed-particle decays. The search differs...

Measurement of $D^0$ production in neutrino charged-current interactions (2002)

Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Melzer, O, Oldeman, R G C, ...

During the years 1994--1997, the emulsion target of the CHORUS detector was exposed to the Wide Band Neutrino Beam from the CERN-SPS. About 170,000 neutrino interactions were successfully located in...

Fighting by sleep-deprived rats as a possible manifestation of panic: effects of sodium lactate (2001)

Furlan,F.A., Hoshino,K.

Increased fighting is an effect of desynchronized sleep deprivation (DSD) in rats, and recently this behavior has been suggested to be spontaneous panic and equivalent to panic disorder. In the...

Observation of weak neutral current neutrino production of $J/\psi$ (2001)

Eskut, E, Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Konijn, J, ...

Observation of \jpsi production by neutrinos in the calorimeter of the CHORUS detector exposed to the CERN SPS wide-band \numu beam is reported. A spectrum-averaged cross-section...

Observation of weak neutral current neutrino production of $J/\psi$ (2001)

Eskut, E., Kayis-Topaksu, A., Onenguet, G., Van Dantzig, R., De Jong, M., Konijn, J., ...

Observation of \jpsi production by neutrinos in the calorimeter of the CHORUS detector exposed to the CERN SPS wide-band \numu beam is reported. A spectrum-averaged cross-section...

New results from a search for $\nu_{\mu} \to \nu_{\tau}$ and $\nu_{e} \to \nu_{\tau}$ oscillation (2001)

Eskut, E., Kayis-Topaksu, A., Onenguet, G., Van Dantzig, R., De Jong, M., Konijn, J., ...

A first analysis of the complete set of data collected by CHORUS in the years 1994-1997 is presented. The search for $\nut$ charged current events has been performed for both leptonic and hadronic...

Observation of weak neutral current neutrino production of $J/\psi$ (2001)

Eskut, E., Kayis-Topaksu, A., Onenguet, G., Van Dantzig, R., De Jong, M., Konijn, J., ...

Observation of \jpsi production by neutrinos in the calorimeter of the CHORUS detector exposed to the CERN SPS wide-band \numu beam is reported. A spectrum-averaged cross-section...

New results from a search for $\nu_{\mu} \to \nu_{\tau}$ and $\nu_{e} \to \nu_{\tau}$ oscillation (2001)

Eskut, E., Kayis-Topaksu, A., Onenguet, G., Van Dantzig, R., De Jong, M., Konijn, J., ...

A first analysis of the complete set of data collected by CHORUS in the years 1994-1997 is presented. The search for $\nut$ charged current events has been performed for both leptonic and hadronic...

Observation of weak neutral current neutrino production of $J/\psi$ (2001)

Eskut, E., Kayis-Topaksu, A., Onenguet, G., Van Dantzig, R., De Jong, M., Konijn, J., ...

Observation of \jpsi production by neutrinos in the calorimeter of the CHORUS detector exposed to the CERN SPS wide-band \numu beam is reported. A spectrum-averaged cross-section...

New results from a search for $\nu_{\mu} \to \nu_{\tau}$ and $\nu_{e} \to \nu_{\tau}$ oscillation (2001)

Eskut, E., Kayis-Topaksu, A., Onenguet, G., Van Dantzig, R., De Jong, M., Konijn, J., ...

A first analysis of the complete set of data collected by CHORUS in the years 1994-1997 is presented. The search for $\nut$ charged current events has been performed for both leptonic and hadronic...

Observation of weak neutral current neutrino production of $J/\psi$ (2001)

Eskut, E., Kayis-Topaksu, A., Onenguet, G., Van Dantzig, R., De Jong, M., Konijn, J., ...

Observation of \jpsi production by neutrinos in the calorimeter of the CHORUS detector exposed to the CERN SPS wide-band \numu beam is reported. A spectrum-averaged cross-section...

New results from a search for $\nu_{\mu} \to \nu_{\tau}$ and $\nu_{e} \to \nu_{\tau}$ oscillation (2001)

Eskut, E., Kayis-Topaksu, A., Onenguet, G., Van Dantzig, R., De Jong, M., Konijn, J., ...

A first analysis of the complete set of data collected by CHORUS in the years 1994-1997 is presented. The search for $\nut$ charged current events has been performed for both leptonic and hadronic...

Observation of weak neutral current neutrino production of $J/\psi$ (2001)

Eskut, E., Kayis-Topaksu, A., Onenguet, G., Van Dantzig, R., De Jong, M., Konijn, J., ...

Observation of \jpsi production by neutrinos in the calorimeter of the CHORUS detector exposed to the CERN SPS wide-band \numu beam is reported. A spectrum-averaged cross-section...

New results from a search for $\nu_{\mu} \to \nu_{\tau}$ and $\nu_{e} \to \nu_{\tau}$ oscillation (2001)

Eskut, E., Kayis-Topaksu, A., Onenguet, G., Van Dantzig, R., De Jong, M., Konijn, J., ...

A first analysis of the complete set of data collected by CHORUS in the years 1994-1997 is presented. The search for $\nut$ charged current events has been performed for both leptonic and hadronic...

New results from a search for $\nu_{\mu} \to \nu_{\tau}$ and $\nu_{e} \to \nu_{\tau}$ oscillation (2000)

Eskut, E, Kayis-Topaksu, A, Onengüt, G, Van Dantzig, R, De Jong, M, Konijn, J, ...

A first analysis of the complete set of data collected by CHORUS in the years 1994-1997 is presented. The search for $\nut$ charged current events has been performed for both leptonic and hadronic...

Electrolocation-communication discharges of the fish Gymnotus carapo L. (Gymnotidae: Gymnotiformes) during behavioral sleep (1999)

Stopa,R.M., Hoshino,K.

Technical problems have hampered the study of sleep in teleosts. The electrical discharges of Gymnotus carapo L. (Gymnotidae: Gymnotiformes) were monitored to evaluate their ease and reliability as...

Observation of neutrino induced diffractive $D_s^{*+}$ production and subsequent decay $D_s^{*+} \to D_s^+ \to \tau^+ \to \mu^+$ (1998)

Annis, P, Aoki, S, Artamonov, S A, Barbuto, E, Di Bartolomeo, A, Bonekämper, D, ...

We report on the first direct observation of a neutrino induced charged-current interaction with two subsequent decays of short-lived particles close to the interaction vertex. This rare double- kink...

Search for $\nu_\mu \to \nu_\tau$ oscillation using the $\tau$ decay modes into a single charged particle (1998)

Eskut, E, Kayis, A, Onengüt, G, Van Dantzig, R, De Jong, M, Konijn, J, ...

Part of the neutrino events collected in 1994-1995 by the CHORUS experiment has been analysed. A search was performed for $\nu_{\tau}$ charged current interactions followed by the $\tau$ lepton deca...

Neuroethologic differences in sleep deprivation induced by the single- and multiple-platform methods (1998)

Medeiros,R., Lenneberg-Hoshino,C., Hoshino,K., Tufik,S.

It has been proposed that the multiple-platform method (MP) for desynchronized sleep (DS) deprivation eliminates the stress induced by social isolation and by the restriction of locomotion in the...

A Search for $\nu_\mu \to \nu_\tau$ Oscillation (1998)

Eskut, E, Kayis, A, Onengüt, G, Van Dantzig, R, De Jong, M, Konijn, J, ...

CHORUS is an experiment searching for $\numtonut$ oscillation in the CERN wide band neutrino beam with a {\sl hybrid} setup consisting of a nuclear emulsion target followed by electronic detectors....

The CHORUS experiment to search for $\nu_{\mu} \rightarrow \nu_{\tau}$ oscillation (1997)

Eskut, E, Kayis, A, Onengüt, G, Van Dantzig, R, Konijn, J, Oldeman, R G C, ...

A new experimental apparatus, designed principally for a high sensitivity search for $\nu_{\mu}~\rightarrow~\nu_{\tau}$ oscillation, has been successfully constructed and made operational by the...

The CHORUS neutrino oscillation search experiment (1997)

Eskut, E, Kayis, A, Onengüt, G, Van Dantzig, R, Konijn, J, Oldeman, R G C, ...

The CHORUS experiment has successfully finished run I (320~000 recorded \numu\ CC in 94/95) and performed half of run II (225~000 \numu\ CC in 96). The analysis chain was exercised on a small data...

Measurement of B(D_s+ -> mu+ nu_mu)/B(D_s+ -> phi mu+ nu_mu) and Determination of the Decay Constant f_{D_s} (1996)

Kodama, K., Torikai, S., Ushida, N., Mokhtarani, A., Paolone, V. S., Volk, J. T., ...

We have observed $23.2 \pm 6.0_{-0.9}^{+1.0}$ purely-leptonic decays of $D_s^+ -> \mu^+ \nu_\mu$ from a sample of muonic one prong decay events detected in the emulsion target of Fermilab experiment...

Damping Capacity of Hypo-Eutectic Zn-Al Alloys (1996)

Kurosawa, T., Otani, T., Hoshino, K.

Damping capacity of hypo-eutectic Zn-Al alloys as a function of rolling ratio is investigated. Effect of heat treatment after cold rolling on the damping capacity is discussed. Damping tests were...

Damping Capacity of Hypo-Eutectic Zn-Al Alloys (1996)

Kurosawa, T., Otani, T., Hoshino, K.

Damping capacity of hypo-eutectic Zn-Al alloys as a function of rolling ratio is investigated. Effect of heat treatment after cold rolling on the damping capacity is discussed. Damping tests were...

Damping Capacity of Hypo-Eutectic Zn-Al Alloys (1996)

Kurosawa, T., Otani, T., Hoshino, K.

Damping capacity of hypo-eutectic Zn-Al alloys as a function of rolling ratio is investigated. Effect of heat treatment after cold rolling on the damping capacity is discussed. Damping tests were...

DAMPING CAPACITY OF Zn-Al ALLOY CASTINGS (1985)

Otani, T., Sakai, T., Hoshino, K., Kurosawa, T.

This paper describes the damping capacity of Zn-15 ~ 27%Al and Zn-15 ~ 27%Al-0.02%Mg alloys casting. Such alloys are desirable to provide high damping of vibration. Cooling rates of solidification...

DAMPING CAPACITY OF Zn-Al ALLOY CASTINGS (1985)

Otani, T., Sakai, T., Hoshino, K., Kurosawa, T.

This paper describes the damping capacity of Zn-15 ~ 27%Al and Zn-15 ~ 27%Al-0.02%Mg alloys casting. Such alloys are desirable to provide high damping of vibration. Cooling rates of solidification...

DAMPING CAPACITY OF Zn-Al ALLOY CASTINGS (1985)

Otani, T., Sakai, T., Hoshino, K., Kurosawa, T.

This paper describes the damping capacity of Zn-15 ~ 27%Al and Zn-15 ~ 27%Al-0.02%Mg alloys casting. Such alloys are desirable to provide high damping of vibration. Cooling rates of solidification...

DAMPING CAPACITY AND MECHANICAL PROPERTIES OF Zn-Al ALLOY CASTINGS (1981)

Otani, T., Hoshino, K., Kurosawa, T.

This paper describes damping capacity and mechanical properties of Zn-8~20%Al and Zn-8~20%Al-0.02~0.04%Mg alloy castings. Zn-8~20%Al alloy castings show high damping when quenched from 573K. Small...

DAMPING CAPACITY AND MECHANICAL PROPERTIES OF Zn-Al ALLOY CASTINGS (1981)

Otani, T., Hoshino, K., Kurosawa, T.

This paper describes damping capacity and mechanical properties of Zn-8~20%Al and Zn-8~20%Al-0.02~0.04%Mg alloy castings. Zn-8~20%Al alloy castings show high damping when quenched from 573K. Small...

DAMPING CAPACITY AND MECHANICAL PROPERTIES OF Zn-Al ALLOY CASTINGS (1981)

Otani, T., Hoshino, K., Kurosawa, T.

This paper describes damping capacity and mechanical properties of Zn-8~20%Al and Zn-8~20%Al-0.02~0.04%Mg alloy castings. Zn-8~20%Al alloy castings show high damping when quenched from 573K. Small...

ENTROPY OF LIQUID PSEUDOBINARY ALLOYS (1980)

Hoshino, K., Young, W.

A theory is proposed for the entropy of mixing of compound forming liquid binary alloys on the basis of the hard sphere model, in which formation of "molecules" or "chemical complexes" is assumed. In...

ENTROPY OF LIQUID PSEUDOBINARY ALLOYS (1980)

Hoshino, K., Young, W.

A theory is proposed for the entropy of mixing of compound forming liquid binary alloys on the basis of the hard sphere model, in which formation of "molecules" or "chemical complexes" is assumed. In...

ENTROPY OF LIQUID PSEUDOBINARY ALLOYS (1980)

Hoshino, K., Young, W.

A theory is proposed for the entropy of mixing of compound forming liquid binary alloys on the basis of the hard sphere model, in which formation of "molecules" or "chemical complexes" is assumed. In...

Contribution of the C-8 substituent of DU-6859a, a new potent fluoroquinolone, to its activity against DNA gyrase mutants of Pseudomonas aeruginosa.

Kitamura, A, Hoshino, K, Kimura, Y, Hayakawa, I, Sato, K

Inhibitory effects of five quinolones against DNA gyrases purified from four quinolone-resistant clinical isolates of Pseudomonas aeruginosa and the quinolone-susceptible strain PAO1 were examined....

Quinolone-resistant mutants of escherichia coli DNA topoisomerase IV parC gene.

Kumagai, Y, Kato, J I, Hoshino, K, Akasaka, T, Sato, K, Ikeda, H

Escherichia coli quinolone-resistant strains with mutations of the parC gene, which codes for a subunit of topoisomerase IV, were isolated from a quinolone-resistant gyrA mutant of DNA gyrase....

Mechanism of differential activities of ofloxacin enantiomers.

Morrissey, I, Hoshino, K, Sato, K, Yoshida, A, Hayakawa, I, Bures, M G, ...

Ofloxacin, a potent quinolone antibacterial agent, has a tricyclic ring structure with a methyl group attached to the asymmetric carbon at the C-3 position on the oxazine ring. The S isomer (DR-3355)...

Inhibitory effects of quinolones on DNA gyrase of Escherichia coli and topoisomerase II of fetal calf thymus.

Hoshino, K, Sato, K, Une, T, Osada, Y

The in vitro inhibitory effects of quinolones on the bacterial DNA gyrase of Escherichia coli KL-16 and topoisomerase II of fetal calf thymus were compared. All the quinolones tested required higher...

Comparison of inhibition of Escherichia coli topoisomerase IV by quinolones with DNA gyrase inhibition.

Hoshino, K, Kitamura, A, Morrissey, I, Sato, K, Kato, J, Ikeda, H

In order to examine the inhibitory activities of quinolones against topoisomerase IV, both subunits of this enzyme, ParC and ParE, were purified from Escherichia coli. The specific activity of...

Antimicrobial activity of DU-6859, a new potent fluoroquinolone, against clinical isolates.

Sato, K, Hoshino, K, Tanaka, M, Hayakawa, I, Osada, Y

DU-6859, (-)-7-[(7S)-amino-5-azaspiro(2,4)heptan-5-yl]-8-chloro-6- fluoro-1-[(1R,2R)-cis-2-fluoro-1-cyclopropyl]-1,4-dihydro-4-oxoquinol one-3- carboxylic acid, is a new fluoroquinolone with...

Antimicrobial activity of DV-7751a, a new fluoroquinolone.

Tanaka, M, Hoshino, K, Ishida, H, Sato, K, Hayakawa, I, Osada, Y

We compared the in vitro antibacterial activity of DV-7751a against gram-positive and -negative bacteria with those of quinolones currently available. MICs for 90% of the strains tested (MIC90s)...

Rapid induction of alpha-amylase by nongrowing mycelia of Aspergillus oryzae.

Yabuki, M, Ono, N, Hoshino, K, Fukui, S

A rapid induction system for synthesis of alpha-amylase by the funga Aspergillus oryzae M-13 was established. The mycelia were prepared from 20-h cultures grown on a peptone-glycerol medium and...

Significance of the methyl group on the oxazine ring of ofloxacin derivatives in the inhibition of bacterial and mammalian type II topoisomerases.

Hoshino, K, Sato, K, Akahane, K, Yoshida, A, Hayakawa, I, Sato, M, ...

A study was made of the correlation between the in vitro inhibitory effects of several quinolones, including four ofloxacin derivatives, on bacterial DNA gyrase from Escherichia coli KL-16 and on...

Multiple regulation of ornithine decarboxylase in enzyme-overproducing cells.

Kameji, T, Hayashi, S, Hoshino, K, Kakinuma, Y, Igarashi, K

We have isolated from mouse FM3A cells a variant cell line, termed EXOD-1, that overproduces ornithine decarboxylase (ODC). The cells were resistant to alpha-difluoromethylornithine, an irreversible...

Contribution of the C-8 substituent of DU-6859a, a new potent fluoroquinolone, to its activity against DNA gyrase mutants of Pseudomonas aeruginosa.

Kitamura, A, Hoshino, K, Kimura, Y, Hayakawa, I, Sato, K

Inhibitory effects of five quinolones against DNA gyrases purified from four quinolone-resistant clinical isolates of Pseudomonas aeruginosa and the quinolone-susceptible strain PAO1 were examined....

Quinolone-resistant mutants of escherichia coli DNA topoisomerase IV parC gene.

Kumagai, Y, Kato, J I, Hoshino, K, Akasaka, T, Sato, K, Ikeda, H

Escherichia coli quinolone-resistant strains with mutations of the parC gene, which codes for a subunit of topoisomerase IV, were isolated from a quinolone-resistant gyrA mutant of DNA gyrase....

Mechanism of differential activities of ofloxacin enantiomers.

Morrissey, I, Hoshino, K, Sato, K, Yoshida, A, Hayakawa, I, Bures, M G, ...

Ofloxacin, a potent quinolone antibacterial agent, has a tricyclic ring structure with a methyl group attached to the asymmetric carbon at the C-3 position on the oxazine ring. The S isomer (DR-3355)...

Inhibitory effects of quinolones on DNA gyrase of Escherichia coli and topoisomerase II of fetal calf thymus.

Hoshino, K, Sato, K, Une, T, Osada, Y

The in vitro inhibitory effects of quinolones on the bacterial DNA gyrase of Escherichia coli KL-16 and topoisomerase II of fetal calf thymus were compared. All the quinolones tested required higher...

Comparison of inhibition of Escherichia coli topoisomerase IV by quinolones with DNA gyrase inhibition.

Hoshino, K, Kitamura, A, Morrissey, I, Sato, K, Kato, J, Ikeda, H

In order to examine the inhibitory activities of quinolones against topoisomerase IV, both subunits of this enzyme, ParC and ParE, were purified from Escherichia coli. The specific activity of...

Antimicrobial activity of DU-6859, a new potent fluoroquinolone, against clinical isolates.

Sato, K, Hoshino, K, Tanaka, M, Hayakawa, I, Osada, Y

DU-6859, (-)-7-[(7S)-amino-5-azaspiro(2,4)heptan-5-yl]-8-chloro-6- fluoro-1-[(1R,2R)-cis-2-fluoro-1-cyclopropyl]-1,4-dihydro-4-oxoquinol one-3- carboxylic acid, is a new fluoroquinolone with...

Antimicrobial activity of DV-7751a, a new fluoroquinolone.

Tanaka, M, Hoshino, K, Ishida, H, Sato, K, Hayakawa, I, Osada, Y

We compared the in vitro antibacterial activity of DV-7751a against gram-positive and -negative bacteria with those of quinolones currently available. MICs for 90% of the strains tested (MIC90s)...

Rapid induction of alpha-amylase by nongrowing mycelia of Aspergillus oryzae.

Yabuki, M, Ono, N, Hoshino, K, Fukui, S

A rapid induction system for synthesis of alpha-amylase by the funga Aspergillus oryzae M-13 was established. The mycelia were prepared from 20-h cultures grown on a peptone-glycerol medium and...

Significance of the methyl group on the oxazine ring of ofloxacin derivatives in the inhibition of bacterial and mammalian type II topoisomerases.

Hoshino, K, Sato, K, Akahane, K, Yoshida, A, Hayakawa, I, Sato, M, ...

A study was made of the correlation between the in vitro inhibitory effects of several quinolones, including four ofloxacin derivatives, on bacterial DNA gyrase from Escherichia coli KL-16 and on...

Multiple regulation of ornithine decarboxylase in enzyme-overproducing cells.

Kameji, T, Hayashi, S, Hoshino, K, Kakinuma, Y, Igarashi, K

We have isolated from mouse FM3A cells a variant cell line, termed EXOD-1, that overproduces ornithine decarboxylase (ODC). The cells were resistant to alpha-difluoromethylornithine, an irreversible...

Rigid spine syndrome with respiratory failure.

Morita, H, Kondo, K, Hoshino, K, Maruyama, K, Yanagisawa, N

The pathogenesis and therapy of respiratory failure in the rigid spine syndrome are discussed in two cases who improved with respiratory assistance. In both cases, the partial pressures of oxygen and...