Kai Ewert

Transitions between distinct compaction regimes in complexes of multivalent cationic lipids and DNA (2008)

Farago, Oded, Ewert, Kai, Ahmad, Ayesha, Evans, Heather M., Gr\onbech-Jensen, Niels, Safinya, Cyrus R.

We use X-ray scattering and molecular simulations to investigate the structural properties of complexes of multivalent cationic lipids and DNA molecules. At low mole fraction of neutral lipids (NLs),...

Synthese und Charakterisierung photorefraktiver Polymere und Modellverbindungen / (1998)

Ewert, Kai.

Thesis (doctoral)--Universität Stuttgart, 1998.

Surface Functionalized Cationic Lipid-DNA Complexes for Gene Delivery: PEGylated Lamellar Complexes Exhibit Distinct DNA-DNA Interaction Regimes

Martin-Herranz, Ana, Ahmad, Ayesha, Evans, Heather M., Ewert, Kai, Schulze, Uwe, Safinya, Cyrus R.

Cationic lipid-DNA (CL-DNA) complexes are abundantly used in nonviral gene therapy clinical applications. Surface functionality is the next step in developing these complexes as competent,...

Radial Compression of Microtubules and the Mechanism of Action of Taxol and Associated Proteins

Needleman, Daniel J., Ojeda-Lopez, Miguel A., Raviv, Uri, Ewert, Kai, Miller, Herbert P., Wilson, Leslie, ...

Microtubules (MTs) are hollow cylindrical polymers composed of αβ-tubulin heterodimers that align head-to-tail in the MT wall, forming linear protofilaments that interact laterally. We introduce a...

Surface Functionalized Cationic Lipid-DNA Complexes for Gene Delivery: PEGylated Lamellar Complexes Exhibit Distinct DNA-DNA Interaction Regimes

Martin-Herranz, Ana, Ahmad, Ayesha, Evans, Heather M., Ewert, Kai, Schulze, Uwe, Safinya, Cyrus R.

Cationic lipid-DNA (CL-DNA) complexes are abundantly used in nonviral gene therapy clinical applications. Surface functionality is the next step in developing these complexes as competent,...

Radial Compression of Microtubules and the Mechanism of Action of Taxol and Associated Proteins

Needleman, Daniel J., Ojeda-Lopez, Miguel A., Raviv, Uri, Ewert, Kai, Miller, Herbert P., Wilson, Leslie, ...

Microtubules (MTs) are hollow cylindrical polymers composed of αβ-tubulin heterodimers that align head-to-tail in the MT wall, forming linear protofilaments that interact laterally. We introduce a...

Transitions between Distinct Compaction Regimes in Complexes of Multivalent Cationic Lipids and DNA

Farago, Oded, Ewert, Kai, Ahmad, Ayesha, Evans, Heather M., Grønbech-Jensen, Niels, Safinya, Cyrus R.

Cationic lipids (CLs) have found widespread use as nonviral gene carriers (vectors), including applications in clinical trials of gene therapy. However, their observed transfection efficiencies (TEs)...