Keith D. Garlid

cGMP signalling in pre- and post-conditioning: the role of mitochondria (2008)

Costa, Alexandre D.T., Pierre, Sandrine V., Cohen, Michael V., Downey, James M., Garlid, Keith D.

Much of cell death from ischaemia/reperfusion in heart and other tissues is generally thought to arise from mitochondrial permeability transition (MPT) in the first minutes of reperfusion. In...

Ouabain triggers preconditioning through activation of the Na+,K+-ATPase signaling cascade in rat hearts (2007)

Pierre, Sandrine V., Yang, Changjun, Yuan, Zhaokan, Seminerio, Jennifer, Mouas, Christian, Garlid, Keith D., ...

Objective: Because ouabain activates several pathways that are critical to cardioprotective mechanisms such as ischemic preconditioning, we tested if this digitalis compound could protect the heart...

cGMP Signaling in Pre- and Postconditioning: The Role of Mitochondria (2007)

Costa, Alexandre D. T., Pierre, Sandrine V., Cohen, Michael V., Downey, James M., Garlid, Keith D.

Much of cell death from ischemia/reperfusion in heart and other tissues is generally thought to arise from mitochondrial permeability transition (MPT) in the first minutes of reperfusion. In ischemic...

cGMP signalling in pre- and post-conditioning: the role of mitochondria (2007)

Costa, Alexandre D.T., Pierre, Sandrine V., Cohen, Michael V., Downey, James M., Garlid, Keith D.

Much of cell death from ischemia/reperfusion in heart and other tissues is generally thought to arise from mitochondrial permeability transition (MPT) in the first minutes of reperfusion. In ischemic...

The K+/H+ antiporter of mitochondria and its role in volume homeostasis /--Keith D. Garlid. (1987)

Garlid, Keith D.

Author's thesis comprises thirteen published papers, and one submitted for publication, from 1977 to 1985.

The K+/H+ antiporter of mitochondria and its role in volume homeostasis /--Keith D. Garlid. (1987)

Garlid, Keith D.

Author's thesis comprises thirteen published papers, and one submitted for publication, from 1977 to 1985.

Intramitochondrial signaling: interactions among mitoKATP, PKCɛ, ROS, and MPT

Costa, Alexandre D. T., Garlid, Keith D.

Activation of protein kinase Cɛ (PKCɛ), opening of mitochondrial ATP-sensitive K+ channels (mitoKATP), and increased mitochondrial reactive oxygen species (ROS) are key events in the signaling that...

Conditioning the heart induces formation of signalosomes that interact with mitochondria to open mitoKATP channels

Quinlan, Casey L., Costa, Alexandre D. T., Costa, Cinthia L., Pierre, Sandrine V., Dos Santos, Pierre, Garlid, Keith D.

Perfusion of the heart with bradykinin triggers cellular signaling events that ultimately cause opening of mitochondrial ATP-sensitive K+ (mitoKATP) channels, increased H2O2 production, inhibition of...