Artemisinin-Resistant Mutants of Toxoplasma gondii Have Altered Calcium Homeostasis � (2007)
Kisaburo Nagamune, L. David Sibley
Artemisinin is a plant sesquiterpene lactone that has become an important drug for combating malaria, especially in regions where resistance to other drugs is widespread. While the mechanism of...
Nagamune, Kisaburo, Sibley, L. David
The phylum Apicomplexa comprises a large group of early branching eukaryotes that includes a number of human and animal parasites. Calcium controls a number of vital processes in apicomplexans...
Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei
Nagamune, Kisaburo, Nozaki, Tomoyoshi, Maeda, Yusuke, Ohishi, Kazuhito, Fukuma, Toshihide, Hara, Tatsuru, ...
Trypanosoma brucei, the protozoan parasite responsible for sleeping sickness, evades the immune response of mammalian hosts and digestion in the gut of the insect vector by means of its coat proteins...
Nagamune, Kisaburo, Ohishi, Kazuhito, Ashida, Hisashi, Hong, Yeonchul, Hino, Jun, Kangawa, Kenji, ...
Glycosylphosphatidylinositol (GPI) anchor is a membrane attachment mechanism for cell surface proteins widely used in eukaryotes. GPIs are added to proteins posttranslationally by a complex enzyme,...
Chini, Eduardo N., Nagamune, Kisaburo, Wetzel, Dawn M., Sibley, L. David
The protozoan parasite Toxoplasma gondii relies on calcium-mediated exocytosis to secrete adhesins on to its surface where they can engage host cell receptors. Increases in intracellular calcium...
Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei
Nagamune, Kisaburo, Nozaki, Tomoyoshi, Maeda, Yusuke, Ohishi, Kazuhito, Fukuma, Toshihide, Hara, Tatsuru, ...
Trypanosoma brucei, the protozoan parasite responsible for sleeping sickness, evades the immune response of mammalian hosts and digestion in the gut of the insect vector by means of its coat proteins...
Nagamune, Kisaburo, Ohishi, Kazuhito, Ashida, Hisashi, Hong, Yeonchul, Hino, Jun, Kangawa, Kenji, ...
Glycosylphosphatidylinositol (GPI) anchor is a membrane attachment mechanism for cell surface proteins widely used in eukaryotes. GPIs are added to proteins posttranslationally by a complex enzyme,...
Chini, Eduardo N., Nagamune, Kisaburo, Wetzel, Dawn M., Sibley, L. David
The protozoan parasite Toxoplasma gondii relies on calcium-mediated exocytosis to secrete adhesins on to its surface where they can engage host cell receptors. Increases in intracellular calcium...
Artemisinin-Resistant Mutants of Toxoplasma gondii Have Altered Calcium Homeostasis▿
Nagamune, Kisaburo, Moreno, Silvia N. J., Sibley, L. David
Artemisinin is a plant sesquiterpene lactone that has become an important drug for combating malaria, especially in regions where resistance to other drugs is widespread. While the mechanism of...
Nagamune, Kisaburo, Beatty, Wandy L., Sibley, L. David
Intracellular calcium controls several crucial cellular events in apicomplexan parasites, including protein secretion, motility, and invasion into and egress from host cells. The plant compound...
Surface Sialic Acids Taken from the Host Allow Trypanosome Survival in Tsetse Fly Vectors
Nagamune, Kisaburo, Acosta-Serrano, Alvaro, Uemura, Haruki, Brun, Reto, Kunz-Renggli, Christina, Maeda, Yusuke, ...
The African trypanosome Trypanosoma brucei, which causes sleeping sickness in humans and Nagana disease in livestock, is spread via blood-sucking Tsetse flies. In the fly's intestine, the...
Plants, endosymbionts and parasites: Abscisic acid and calcium signaling
Nagamune, Kisaburo, Xiong, Liming, Chini, Eduardo, Sibley, L David
It was recently discovered that the protozoan parasite, Toxoplasma gondii produces and uses the plant hormone, abscisic acid (ABA), for communication. Following intracellular replication, ABA...