Bauer, Axel, Barthel, Petra, Schneider, Raphael, Ulm, Kurt, Müller, Alexander, Joeinig, Anke, ...
Aims To investigate the combination of heart rate turbulence (HRT) and deceleration capacity (DC) as risk predictors in post-infarction patients with left ventricular ejection fraction (LVEF) > 30%. ...
Schulz, Stefanie, Schuster, Tibor, Mehilli, Julinda, Byrne, Robert A., Ellert, Julia, Massberg, Steffen, ...
Aims To assess the incidence, timing, and relation of drug-eluting stent (DES) thrombosis to discontinuation of clopidogrel therapy. Methods and results This prospective observational cohort study...
Responder Identification in Clinical Trials with Censored Data 2 Summary (2008)
Victoria Kehl, Kurt Ulm, Kehl Ulm
We present a newly developed technique for identification of positive and negative responders to a new treatment which was compared to a classical treatment (or placebo) in a randomized clinical...
Risk stratification after acute myocardial infarction by heart rate turbulence (2008)
Petra Barthel, Raphael Schneider, Axel Bauer, Kurt Ulm, Claus Schmitt, Georg Schmidt, ...
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Implementation of complex interactions in a (2008)
Cox Regression Framework, Martina Müller, Kurt Ulm
The standard Cox proportional hazards model has been extended by functionally describable interaction terms. The first of which are related to neural networks by adopting the idea of transforming...
Responder Identification in Clinical Trials with Censored Data 2 Summary (2008)
Victoria Kehl, Kurt Ulm, Kehl Ulm
We present a newly developed technique for identification of positive and negative responders to a new treatment which was compared to a classical treatment (or placebo) in a randomized clinical...
Two Survival Tree Models for Myocardial Infarction Patients (2007)
This paper is a response to the discussion paper by Ulm et al (2000), which suggests a Cox model for calculating the risk stratification of the MPIP data set patients including the predictors...
On the use of Fractional Polynomials in Dynamic Cox Models (2007)
Ursula Berger, Pia Gerein, Kurt Ulm, Juliane Schäfer
Despite a sophisticated research on modelling of survival data in the last years, the most popular model used in practice is still the proportional hazards regression model proposed by Cox (1972)....
Kurt Ulm, Georg Schmidt, Petra Barthel, Raphael Schneider, Victoria Pashova, Linda Rolnitzky, ...
this paper is based on the proportional hazard model of Cox
Tests for Trends in Binary Response (2007)
Kurt Ulm, Felix Dannegger, Ursula Becker
this paper the CA--test will be compared with the isotonic regression. First a simulation study is performed where several conditions are investigated. Afterwards the para--aramid data are considered...
Bauer, Axel, Watanabe, Mari A., Barthel, Petra, Schneider, Raphael, Ulm, Kurt, Schmidt, Georg
Aims To assess the association of prolonged QRS duration and late mortality in unselected post-infarction patients of the revascularization era. Methods and results A total of 1455 survivors of acute...
A non-parametric framework for estimating threshold limit values (2005)
Abstract Background To estimate a threshold limit value for a compound known to have harmful health effects, an 'elbow' threshold model is usually applied. We are interested on non-parametric...
Bauer, Axel, Guzik, Przemyslaw, Barthel, Petra, Schneider, Raphael, Ulm, Kurt, Watanabe, Mari A., ...
Aims To test the prognostic value of ventricular late potentials (LPs) in a large cohort of post-infarction patients in the modern reperfusion era. Methods and results 1800 consecutive survivors of...
Bauer, Axel, Watanabe, Mari A., Barthel, Petra, Schneider, Raphael, Ulm, Kurt, Schmidt, Georg
Aims To assess the association of prolonged QRS duration and late mortality in unselected post-infarction patients of the revascularization era. Methods and results A total of 1455 survivors of acute...
Responder Identification in Clinical Trials with Censored Data (2003)
We present a newly developed technique for identification of positive and negative responders to a new treatment which was compared to a classical treatment (or placebo) in a randomized clinical...
Modelling time-varying effects in Cox model under order restrictions (2003)
The violation of the proportional hazards assumption in Cox model occurs quite often in studies concerning solid tumours or leukaemia. Then the time varying coefficients model is its most popular...
Implementation of complex interactions in a Cox regression framework (2003)
The standard Cox proportional hazards model has been extended by functionally describable interaction terms. The first of which are related to neural networks by adopting the idea of transforming...
Extension of CART using multiple splits under order restrictions (2003)
Strobl, R., Salanti, G., Ulm, Kurt
CART was introduced by Breiman et al. (1984) as a classification tool. It divides the whole sample recursively in two subpopulations by finding the best possible split with respect to a optimisation...
Ulm, Kurt, Barthel, Petra, Rolnitzky, Linda, Schneider, Raphael, Malik, M., Bigger Jr., J. Thomas, ...
Objectives: Development of risk stratification criteria for predicting mortality in post-infarction patients taking into account LVEF and heart-rate turbulence (HRT). Methods: Based on previous...
Identification of Responders to Amiodarone: Subgroup Analysis of the EMIAT Study (2003)
Kehl, V., Ulm, Kurt, Schmidt, G., Barthel, Petra, Malik, M.
Clinical trials often judge the efficacy of a new treatment by comparing the survival patterns of patients who are randomly assigned to undergo the new or a standard/placebo treatment. Usually, the...
Reck, Martin, Von Pawel, Joachim, Macha, Hans-Nicolas, Kaukel, Eckhard, Deppermann, Karl-Matthias, Bonnet, Reiner, ...
Background: Paclitaxel administered in combination with a topoisomerase-II inhibitor (such as etoposide) and carboplatin is an effective and safe first-line treatment for patients with small-cell...
Look, Maxime P., Duffy, Michael J., Harbeck, Nadia, Christensen, Ib Jarle, Thomssen, Christoph, ...
Background: Urokinase-type plasminogen activator (uPA) and its inhibitor (PAI-1) play essential roles in tumor invasion and metastasis. High levels of both uPA and PAI-1 are associated with poor...
Multidimensional isotonic regression and estimation of the threshold value (2001)
No abstract available!
Modelling Under Order Restrictions (2001)
Order restricted effects of predictors can be represented in models by the monotonic transformation fitted by the pooled adjacent violators algorithm as described by T. Robertson et al. In the...
Multidimensional isotonic regression and estimation of
Bone Metabolism During the Perimenopausal Transition: a Prospective Study (2000)
Seifert-Klauss, V., Mueller, J. E., Probst, R., Wilker, J., Höß, C., Treumann, T., ...
Objective: A study characterizing changes in biochemical markers of bone formation and resorption over the course of one year in premenopausal, perimenopausal and early postmenopausal women is...
Two Survival Tree Models for Myocardial Infarction Patients (2000)
In the search of a better prognostic survival model for post-acute myocardial infarction patients, the scientists at the Technical University of Munich's "Klinikum rechts der Isar" and the German...
Ulm, Kurt, Schmidt, Georg, Barthel, Petra, Schneider, Raphael, Pashova, Victoria, Rolnitzky, Linda, ...
The MPIP data set was used to obtain a model for mortality risk stratification of acute myocardial infarction patients. The predictors heart rate turbulence (HRT) and left-ventricular ejection...
On the use of Fractional Polynomials in Dynamic Cox Models (2000)
Berger, Ursula, Gerein, Pia, Ulm, Kurt, Schäfer, Juliane
Despite a sophisticated research on modelling of survival data in the last years, the most popular model used in practice is still the proportional hazards regression model proposed by Cox (1972)....
Tests for Trends in Binary Response (1998)
Ulm, Kurt, Dannegger, Felix, Becker, Ursula
Tests for trend in binary response are especially important when analyzing animal experiments where the response in various dose--groups is of interest. Among the nonparametric tests the approach of...
Statistische Analyse des Einflusses von Herzrhythmusstörungen auf das Mortalitätsrisiko (1997)
Pruscha, H., Ulm, Kurt, Schmidt, G.
Herzrhythmusstörungen stellen eine äußerst bedrohliche Krankheit dar und können zum plötzlichen Herztod führen. So sterben in der Bundesrepublik Deutschland pro Jahr etwa 100.000 Patienten an...
Bericht über die Auswertung der Daten der Studie "Chronische Bronchitis" (1996)
Ulm, Kurt, Dannegger, Felix, Spanier, M.
Anhand logistischer und additiver Modelle, sowie mittels der isotonen Regression werden Grenzwertvorschläge für die maximale Arbeitsplatzkonzentration (MAK) von Fein- und Gesamtstaubkonzentration...
Variability of ventricular premature complexes and mortality risk (1996)
Schmidt, Georg, Morfill, Gregor E., Barthel, Petra, Hadamitzky, Martin, Kreuzberg, Heinz, Demmel, Valentin, ...
Identification of Prognostic Factors with Censored Data (1995)
Dannegger, Felix, Klinger, Artur, Ulm, Kurt
A major issue in the analysis of diseases is the identification and assessment of prognostic factors relevant to the development of the illness. Statistical analyses within the proportional hazards...
Identification of Prognostic Factors with Censored Data (1995)
Felix Dannegger, Artur Klinger, Kurt Ulm
this paper we use tree based models and varying coefficient models to allow for detectability of prognostic factors with possibly nonadditive, nonlinear and time--varying impact on disease...
Statistisches Verfahren zur Feststellung von Schadstoff-Grenzkonzentrationen in der Medizin. (1985)
München, Techn. Univ., Habil.-Schr., 1985.
Weighardt, Heike, Heidecke, Claus-Dieter, Westerholt, Alexandra, Emmanuilidis, Klaus, Maier, Stefan, Veit, Martin, ...
Weighardt, Heike, Heidecke, Claus-Dieter, Westerholt, Alexandra, Emmanuilidis, Klaus, Maier, Stefan, Veit, Martin, ...
Feterowski, Carolin, Emmanuilidis, Klaus, Miethke, Thomas, Gerauer, Klaus, Rump, Martina, Ulm, Kurt, ...
Genetically determined responsiveness to microbial stimuli such as lipopolysaccharide (LPS) may affect the pathophysiology of human sepsis. The D299G mutation in human Toll-like receptor-4 (TLR4)...