L. C. Bollheimer

Behandlungspfade – praktikable Hilfe für den behandelnden Arzt? (2006)

Audebert, F. X., Büttner, R., Hartmann, P., Schölmerich, J., Bollheimer, L. C.

Zusammenfassung Leitlinien, Behandlungspfade und klinische Algorithmen sind heutzutage beliebte Instrumente zur Qualitätssicherung und Ökonomisierung von ärztlicher Arbeit. Diese Begriffe werden...

Defining high-fat-diet rat models: metabolic and molecular effects of different fat types (2006)

Buettner, R., Parhofer, K. G., Woenckhaus, M., Wrede, C. E., Kunz-Schughart, L. A., Schölmerich, J., ...

High-fat (HF)-diet rodent models have contributed significantly to the analysis of the pathophysiology of the insulin resistance syndrome, but their phenotype varies distinctly between different...

Association between serum ferritin and the insulin resistance syndrome in a representative population (2006)

Wrede, C. E., Buettner, R., Bollheimer, L. C., Schölmerich, J., Hellerbrand, C.

OBJECTIVE: Unexplained hepatic iron overload with increased serum ferritin (SF) values has been associated with the insulin resistance syndrome (IRS), defined by the presence of one or more of the...

Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation.

Bollheimer, L C, Skelly, R H, Chester, M W, McGarry, J D, Rhodes, C J

The pancreatic beta cell normally maintains a stable balance among insulin secretion, insulin production, and insulin degradation to keep optimal intracellular stores of the hormone. Elevated levels...

A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties.

Skelly, R H, Bollheimer, L C, Wicksteed, B L, Corkey, B E, Rhodes, C J

The regulation of proinsulin biosynthesis in pancreatic beta-cells is vital for maintaining optimal insulin stores for glucose-induced insulin release. The majority of nutrient fuels that induce...

Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation.

Bollheimer, L C, Skelly, R H, Chester, M W, McGarry, J D, Rhodes, C J

The pancreatic beta cell normally maintains a stable balance among insulin secretion, insulin production, and insulin degradation to keep optimal intracellular stores of the hormone. Elevated levels...

A distinct difference in the metabolic stimulus-response coupling pathways for regulating proinsulin biosynthesis and insulin secretion that lies at the level of a requirement for fatty acyl moieties.

Skelly, R H, Bollheimer, L C, Wicksteed, B L, Corkey, B E, Rhodes, C J

The regulation of proinsulin biosynthesis in pancreatic beta-cells is vital for maintaining optimal insulin stores for glucose-induced insulin release. The majority of nutrient fuels that induce...