Unraveling the complex trait of seed quality in tomato by genetical genomics (2009)
Ligterink, W., Kazmi, R.H., Kahn, N., Willems, L., Hilhorst, H.W.M.
Unraveling the complex trait of seed quality in tomato (2009)
Ligterink, W., Kazmi, R.H., Kahn, N., Willems, L., Hilhorst, H.W.M.
Genes for seed quality: a physiological genetical genomics approach (2009)
Ligterink, W., Joosen, R.V.L., Kazmi, R.H., Kahn, N., Willems, L., Hilhorst, H.W.M.
Joosen, R.V.L., Kodde, J., Willems, L., Ligterink, W., Plas, L.H.W., Van Der, Hilhorst, H.W.M.
Over the past few decades seed physiology research has contributed to many important scientific discoveries and has provided valuable tools for the production of high quality seeds. An important...
Earlier onset of delta-retrovirus-induced leukemia after splenectomy (2009)
Florins, Arnaud-Francois, Reichert, M, Asquith, B, Bouzar, Amel, Jean, G, Francois, C, ...
Molecular dissection of seed priming treatments (2008)
Ligterink, W., Kodde, J., Lammers, M., Willems, L., Maagd, R.A., De, Hilhorst, H.W.M.
Cré, J., Magez, Walter; U0007538 ;, Willems, L., Olieslagers, K., Van Den Bosch, R., Cocquet, E., ...
Search for gravitational-wave bursts in LIGO data from the fourth science run (2007)
Abbott, B., Abbott, R., Adhikari, R., Agresti, Juri, Ajith, P., Allen, Bruce, ...
The fourth science run of the LIGO and GEO 600 gravitational-wave detectors, carried out in early 2005, collected data with significantly lower noise than previous science runs. We report on a search...
Abbott, B., Abbott, R., Adhikari, R., Agresti, Juri, Ajith, P., Allen, Bruce, ...
The Laser Interferometer Gravitational‐Wave Observatory (LIGO) has performed the fourth science run, S4, with significantly improved interferometer sensitivities with respect to previous runs....
L-Arginine transporters in cardiovascular disease: a novel theraputic target (2007)
Chin-Dusting, J.P.F, Willems, L., Kaye, D.M.
The amino acid L-arginine participates in a variety of key biochemical and physiological activities, including its well-recognized role as the key substrate for nitric oxide (NO) biosynthesis. The...
L-Arginine transporters in cardiovascular disease: a novel theraputic target (2007)
Chin-Dusting, J.P.F, Willems, L., Kaye, D.M.
The amino acid L-arginine participates in a variety of key biochemical and physiological activities, including its well-recognized role as the key substrate for nitric oxide (NO) biosynthesis. The...
Wyers, L. ; JFA; CORA, Willems, L., Schuermans, Annette; U0010090 ;
Evaluation of natural ventilation systems in a landscaped office. (2004)
Breesch, H, Descheemaeker, K, Janssens, A, Willems, L
The Renson office building (Waregem, Belgium) relies on natural ventilation for both indoor air quality and temperature control. Indoor air quality control is provided by a system consisting of...
Lefebvre, L ; JFA; CORA, Vanderplasschen, A, Ciminale, V, Heremans, Hubertine; U0010398 ;, Dangoisse, O, Jauniaux, JC, ...
G4 and p13(II) are accessory proteins encoded by the X region of bovine leukemia virus and human T-cell leukemia virus type 1 (HTLV-1), respectively. Disruption of the G4 and p13(II) open reading...
WILLEMS, L., POUCLET, A., VICAT, J.-P
WILLEMS, L., POUCLET, A., VICAT, J.-P
Weyten, H, Luyten, J, Keizer, K, Willems, L, Leysen, R
In a high-temperature membrane reactor, one of the reaction products is selectively removed from the reaction mixture, thus preventing the mixture from reaching equilibrium. In a previous study [I],...
In vitro and in vivo oncogenic potential of bovine leukemia virus G4 protein (1998)
Kerkhofs, P ; JFA; CORA, Heremans, Hubertine; U0010398 ;, Burny, A, Kettmann, R, Willems, L
In addition to the genes involved in the structure of the viral particle, the bovine leukemia virus (BLV) genome contains a region called X which contains at least four genes, Among them, the tox and...
Bovine herpesvirus 1-induced apoptosis occurs at the G0/G1 phase of the cell cycle (1997)
Hanon, E, Hoornaert, S, Dequiedt, F, Vanderplasschen, Alain, Lyaku, J, Willems, L, ...
We have previously shown that bovine herpesvirus 1 (BHV-1), even when inactivated, induces apoptotic cell death in mitogen-stimulated bovine peripheral blood mononuclear cells (PBMCs) (Hanonet...
Expression of the blv-x open-reading frames as beta-galactosidase fusion proteins (1987)
Gao, Changshui; U0051302 JFA; CORA, Willems, L, Burny, A, Kettmann, R
Attenuation of bovine leukemia virus by deletion of R3 and G4 open reading frames.
Willems, L, Kerkhofs, P, Dequiedt, F, Portetelle, D, Mammerickx, M, Burny, A, ...
Complex oncoviruses contain, in addition to the classical retroviral genes (gag, pol, and env), a region (X) located between the envelope sequences and the 3' long terminal repeat. The X region...
Merezak, C., Pierreux, C., Adam, E., Lemaigre, F., Rousseau, G. G., Calomme, C., ...
Repression of viral expression is a major strategy developed by retroviruses to escape from the host immune response. The absence of viral proteins (or derived peptides) at the surface of an infected...
Reichert, M., Winnicka, A., Willems, L., Kettmann, R., Cantor, G. H.
The cytoplasmic tail of bovine leukemia virus (BLV) transmembrane protein gp30 has multiple amino acid motifs that mimic those present in signaling proteins associated with B-cell and T-cell...
Inhibition of Histone Deacetylases Induces Bovine Leukemia Virus Expression In Vitro and In Vivo
Merezak, C., Reichert, M., Van Lint, C., Kerkhofs, P., Portetelle, D., Willems, L., ...
Packaging into nucleosomes results in a global transcriptional repression as a consequence of exclusion of sequence-specific factors. This inhibition can be relieved by using inhibitors of histone...
Willems, L, Gatot, J S, Mammerickx, M, Portetelle, D, Burny, A, Kerkhofs, P, ...
The bovine leukemia virus (BLV) transmembrane protein (gp30) contains three YXXL motifs at its carboxyterminal end. Two of these motifs have been implicated in vitro in signal transduction pathways...
Adam, E, Kerkhofs, P, Mammerickx, M, Burny, A, Kettman, R, Willems, L
Efficient transcription and replication of the bovine leukemia virus (BLV) genome require both the viral long terminal repeat (LTR) and the virus-coded transcriptional activator Tax, which functions...
Cellular pathways involved in the ex vivo expression of bovine leukemia virus.
Kerkhofs, P, Adam, E, Droogmans, L, Portetelle, D, Mammerickx, M, Burny, A, ...
Bovine leukemia virus (BLV) is the etiologic agent of enzootic bovine leukosis. The virus adopts a strategy based on the lack of viral expression in vivo; only very rare BLV-infected B lymphocytes...
Dequiedt, F, Hanon, E, Kerkhofs, P, Pastoret, P P, Portetelle, D, Burny, A, ...
Bovine leukemia virus (BLV) and the human T-cell leukemia viruses belong to the same subfamily of oncoviruses. Although much attention has focused on the mechanisms of cell proliferation and...
Adam, E, Kerkhofs, P, Mammerickx, M, Kettmann, R, Burny, A, Droogmans, L, ...
The TAR element (Tax-responsive element; also called TxRE) is a major determinant of the regulation of bovine leukemia virus (BLV) expression. In order to gain insight into the mechanisms of viral...
Bovine leukemia virus, an animal model for the study of intrastrain variability.
Willems, L, Thienpont, E, Kerkhofs, P, Burny, A, Mammerickx, M, Kettmann, R
Intradermal injection of a cloned bovine leukemia virus (BLV) provirus (pV344) into sheep allowed direct evaluation of intrastrain variability. A sheep was injected with pV344 DNA mixed with...
In vivo infection of sheep by bovine leukemia virus mutants.
Willems, L, Kettmann, R, Dequiedt, F, Portetelle, D, Vonèche, V, Cornil, I, ...
Direct inoculation of a cloned bovine leukemia virus (BLV) provirus into sheep has allowed study of the viral infectivity of genetic mutants in vivo. Three BLV variants cloned from BLV-induced tumors...
Willems, L, Kettmann, R, Chen, G, Portetelle, D, Burny, A, Derse, D
To gain insight into the cellular regulation of bovine leukemia virus (BLV) trans activation, a lambda-gt11 cDNA library was constructed with mRNA isolated from a BLV-induced tumor and the...
Gillet, L., Minner, F., Detry, B., Farnir, F., Willems, L., Lambot, M., ...
Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus that has a worldwide distribution in the population of cattle. Many factors make human contamination by BoHV-4 likely to occur. In this study, we...
Vonèche, V, Portetelle, D, Kettmann, R, Willems, L, Limbach, K, Paoletti, E, ...
Modified bovine leukemia virus (BLV) glycoproteins were expressed by using vaccinia virus recombinants, and their fusogenic capacities were examined by a syncytia-formation assay. This analysis...
Willems, L, Grimonpont, C, Heremans, H, Rebeyrotte, N, Chen, G, Portetelle, D, ...
The bovine leukemia virus Tax protein transactivates gene expression directed by the viral long terminal repeat (LTR) and contributes to immortalization of primary cells. Theoretical analysis of the...
The bovine leukemia virus p34 is a transactivator protein.
Willems, L, Gegonne, A, Chen, G, Burny, A, Kettmann, R, Ghysdael, J
Recombinant Moloney murine retroviruses containing the BLV post-envelope long open reading frame were constructed and transfected into the psi 2 packaging cell line. They were shown to encode and to...
The 3' region of bovine leukemia virus genome encodes a trans-activator protein.
Rosen, C A, Sodroski, J G, Willems, L, Kettmann, R, Campbell, K, Zaya, R, ...
The genome of bovine leukemia virus (BLV) contains several overlapping, long open reading frames 3' to the envelope gene. Experiments presented here show that the cDNA encompassing the X region open...
Willems, L, Heremans, H, Chen, G, Portetelle, D, Billiau, A, Burny, A, ...
Human T-lymphotropic viruses (HTLV-I and -II) and bovine leukaemia virus (BLV) express transactivator proteins able to increase long terminal repeat (LTR) directed viral expression. These transacting...
Attenuation of bovine leukemia virus by deletion of R3 and G4 open reading frames.
Willems, L, Kerkhofs, P, Dequiedt, F, Portetelle, D, Mammerickx, M, Burny, A, ...
Complex oncoviruses contain, in addition to the classical retroviral genes (gag, pol, and env), a region (X) located between the envelope sequences and the 3' long terminal repeat. The X region...
Merezak, C., Pierreux, C., Adam, E., Lemaigre, F., Rousseau, G. G., Calomme, C., ...
Repression of viral expression is a major strategy developed by retroviruses to escape from the host immune response. The absence of viral proteins (or derived peptides) at the surface of an infected...
Reichert, M., Winnicka, A., Willems, L., Kettmann, R., Cantor, G. H.
The cytoplasmic tail of bovine leukemia virus (BLV) transmembrane protein gp30 has multiple amino acid motifs that mimic those present in signaling proteins associated with B-cell and T-cell...
Inhibition of Histone Deacetylases Induces Bovine Leukemia Virus Expression In Vitro and In Vivo
Merezak, C., Reichert, M., Van Lint, C., Kerkhofs, P., Portetelle, D., Willems, L., ...
Packaging into nucleosomes results in a global transcriptional repression as a consequence of exclusion of sequence-specific factors. This inhibition can be relieved by using inhibitors of histone...
Willems, L, Gatot, J S, Mammerickx, M, Portetelle, D, Burny, A, Kerkhofs, P, ...
The bovine leukemia virus (BLV) transmembrane protein (gp30) contains three YXXL motifs at its carboxyterminal end. Two of these motifs have been implicated in vitro in signal transduction pathways...
Adam, E, Kerkhofs, P, Mammerickx, M, Burny, A, Kettman, R, Willems, L
Efficient transcription and replication of the bovine leukemia virus (BLV) genome require both the viral long terminal repeat (LTR) and the virus-coded transcriptional activator Tax, which functions...
Cellular pathways involved in the ex vivo expression of bovine leukemia virus.
Kerkhofs, P, Adam, E, Droogmans, L, Portetelle, D, Mammerickx, M, Burny, A, ...
Bovine leukemia virus (BLV) is the etiologic agent of enzootic bovine leukosis. The virus adopts a strategy based on the lack of viral expression in vivo; only very rare BLV-infected B lymphocytes...
Dequiedt, F, Hanon, E, Kerkhofs, P, Pastoret, P P, Portetelle, D, Burny, A, ...
Bovine leukemia virus (BLV) and the human T-cell leukemia viruses belong to the same subfamily of oncoviruses. Although much attention has focused on the mechanisms of cell proliferation and...
Adam, E, Kerkhofs, P, Mammerickx, M, Kettmann, R, Burny, A, Droogmans, L, ...
The TAR element (Tax-responsive element; also called TxRE) is a major determinant of the regulation of bovine leukemia virus (BLV) expression. In order to gain insight into the mechanisms of viral...
Bovine leukemia virus, an animal model for the study of intrastrain variability.
Willems, L, Thienpont, E, Kerkhofs, P, Burny, A, Mammerickx, M, Kettmann, R
Intradermal injection of a cloned bovine leukemia virus (BLV) provirus (pV344) into sheep allowed direct evaluation of intrastrain variability. A sheep was injected with pV344 DNA mixed with...
In vivo infection of sheep by bovine leukemia virus mutants.
Willems, L, Kettmann, R, Dequiedt, F, Portetelle, D, Vonèche, V, Cornil, I, ...
Direct inoculation of a cloned bovine leukemia virus (BLV) provirus into sheep has allowed study of the viral infectivity of genetic mutants in vivo. Three BLV variants cloned from BLV-induced tumors...
Willems, L, Kettmann, R, Chen, G, Portetelle, D, Burny, A, Derse, D
To gain insight into the cellular regulation of bovine leukemia virus (BLV) trans activation, a lambda-gt11 cDNA library was constructed with mRNA isolated from a BLV-induced tumor and the...
Gillet, L., Minner, F., Detry, B., Farnir, F., Willems, L., Lambot, M., ...
Bovine herpesvirus 4 (BoHV-4) is a gammaherpesvirus that has a worldwide distribution in the population of cattle. Many factors make human contamination by BoHV-4 likely to occur. In this study, we...
Vonèche, V, Portetelle, D, Kettmann, R, Willems, L, Limbach, K, Paoletti, E, ...
Modified bovine leukemia virus (BLV) glycoproteins were expressed by using vaccinia virus recombinants, and their fusogenic capacities were examined by a syncytia-formation assay. This analysis...
Willems, L, Grimonpont, C, Heremans, H, Rebeyrotte, N, Chen, G, Portetelle, D, ...
The bovine leukemia virus Tax protein transactivates gene expression directed by the viral long terminal repeat (LTR) and contributes to immortalization of primary cells. Theoretical analysis of the...
Willems, L, Heremans, H, Chen, G, Portetelle, D, Billiau, A, Burny, A, ...
Human T-lymphotropic viruses (HTLV-I and -II) and bovine leukaemia virus (BLV) express transactivator proteins able to increase long terminal repeat (LTR) directed viral expression. These transacting...
The bovine leukemia virus p34 is a transactivator protein.
Willems, L, Gegonne, A, Chen, G, Burny, A, Kettmann, R, Ghysdael, J
Recombinant Moloney murine retroviruses containing the BLV post-envelope long open reading frame were constructed and transfected into the psi 2 packaging cell line. They were shown to encode and to...
The 3' region of bovine leukemia virus genome encodes a trans-activator protein.
Rosen, C A, Sodroski, J G, Willems, L, Kettmann, R, Campbell, K, Zaya, R, ...
The genome of bovine leukemia virus (BLV) contains several overlapping, long open reading frames 3' to the envelope gene. Experiments presented here show that the cDNA encompassing the X region open...