Laurence Lecordier

Transmembrane Insertion of the Toxoplasma gondii GRA5 Protein Occurs after Soluble Secretion into the Host Cell

Lecordier, Laurence, Mercier, Corinne, Sibley, L. David, Cesbron-Delauw, Marie-France

The intracellular parasite Toxoplasma gondii resides within a specialized compartment, the parasitophorous vacuole (PV), that resists fusion with host cell endocytic and lysosomal compartments. The...

Enzyme-Linked Immunosorbent Assays Using the Recombinant Dense Granule Antigens GRA6 and GRA1 of Toxoplasma gondii for Detection of Immunoglobulin G Antibodies

Lecordier, Laurence, Fourmaux, Marie-Pierre, Mercier, Corinne, Dehecq, Eric, Masy, E., Cesbron-Delauw, Marie-France

The potential of the dense granule antigens GRA1 and GRA6 of Toxoplasma gondii to be used as diagnosis reagents in a recombinant form was evaluated. Both proteins were expressed in Escherichia coli...

Biogenesis of Nanotubular Network in Toxoplasma Parasitophorous Vacuole Induced by Parasite Proteins

Mercier, Corinne, Dubremetz, Jean-François, Rauscher, Béatrice, Lecordier, Laurence, Sibley, L. David, Cesbron-Delauw, Marie-France

The intracellular parasite Toxoplasma gondii develops within a nonfusogenic vacuole containing a network of elongated nanotubules that form connections with the vacuolar membrane. Parasite secretory...

Transmembrane Insertion of the Toxoplasma gondii GRA5 Protein Occurs after Soluble Secretion into the Host Cell

Lecordier, Laurence, Mercier, Corinne, Sibley, L. David, Cesbron-Delauw, Marie-France

The intracellular parasite Toxoplasma gondii resides within a specialized compartment, the parasitophorous vacuole (PV), that resists fusion with host cell endocytic and lysosomal compartments. The...

Enzyme-Linked Immunosorbent Assays Using the Recombinant Dense Granule Antigens GRA6 and GRA1 of Toxoplasma gondii for Detection of Immunoglobulin G Antibodies

Lecordier, Laurence, Fourmaux, Marie-Pierre, Mercier, Corinne, Dehecq, Eric, Masy, E., Cesbron-Delauw, Marie-France

The potential of the dense granule antigens GRA1 and GRA6 of Toxoplasma gondii to be used as diagnosis reagents in a recombinant form was evaluated. Both proteins were expressed in Escherichia coli...

Biogenesis of Nanotubular Network in Toxoplasma Parasitophorous Vacuole Induced by Parasite Proteins

Mercier, Corinne, Dubremetz, Jean-François, Rauscher, Béatrice, Lecordier, Laurence, Sibley, L. David, Cesbron-Delauw, Marie-France

The intracellular parasite Toxoplasma gondii develops within a nonfusogenic vacuole containing a network of elongated nanotubules that form connections with the vacuolar membrane. Parasite secretory...

Diversification of Function by Different Isoforms of Conventionally Shared RNA Polymerase Subunits

Devaux, Sara, Kelly, Steven, Lecordier, Laurence, Wickstead, Bill, Perez-Morga, David, Pays, Etienne, ...

Eukaryotic nuclei contain three classes of multisubunit DNA-directed RNA polymerase. At the core of each complex is a set of 12 highly conserved subunits of which five—RPB5, RPB6, RPB8, RPB10, and...