Alternative promoter usage of the membrane glycoprotein CD36 (2006)
Andersen Malin, Lenhard Boris, Whatling Carl, Eriksson Per, Odeberg Jacob
Abstract Background CD36 is a membrane glycoprotein involved in a variety of cellular processes such as lipid transport, immune regulation, hemostasis, adhesion, angiogenesis and atherosclerosis. It...
Transcript annotation in FANTOM3: mouse gene catalog based on physical cDNAs. (2006)
Maeda Norihiro, Kasukawa Takeya, Oyama Rieko, Gough Julian, Frith Martin, Engström Pär G, ...
The international FANTOM consortium aims to produce a comprehensive picture of the mammalian transcriptome, based upon an extensive cDNA collection and functional annotation of full-length enriched...
Complex Loci in human and mouse genomes. (2006)
Engström Pär G, Suzuki Harukazu, Ninomiya Noriko, Akalin Altuna, Sessa Luca, Lavorgna Giovanni, ...
Mammalian genomes harbor a larger than expected number of complex loci, in which multiple genes are coupled by shared transcribed regions in antisense orientation and/or by bidirectional core...
Identification of functional SNPs in the 5-prime flanking sequences of human genes (2005)
Mottagui-Tabar Salim, Faghihi Mohammad, Mizuno Yosuke, Engström Pär, Lenhard Boris, Wasserman Wyeth, ...
Abstract Background Over 4 million single nucleotide polymorphisms (SNPs) are currently reported to exist within the human genome. Only a small fraction of these SNPs alter gene function or...
Exploring hepatic hormone actions using a compilation of gene expression profiles (2005)
Ståhlberg Nina, Merino Roxana, Hernández Luis, Fernández-Pérez Leandro, Sandelin Albin, Engström Pär, ...
Abstract Background Microarray analysis is attractive within the field of endocrine research because regulation of gene expression is a key mechanism whereby hormones exert their actions. Knowledge...
Sandelin Albin, Bailey Peter, Bruce Sara, Engström Pär, Klos Joanna, Wasserman Wyeth, ...
Abstract Background Evolutionarily conserved sequences within or adjoining orthologous genes often serve as critical cis-regulatory regions. Recent studies have identified long, non-coding genomic...
Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004)
Imanishi Tadashi, Itoh Takeshi, Suzuki Yutaka, O'Donovan Claire, Fukuchi Satoshi, Koyanagi Kanako O, ...
The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...
Identification of conserved regulatory elements by comparative genome analysis (2003)
Lenhard Boris, Sandelin Albin, Mendoza Luis, Engström Pär, Jareborg Niclas, Wasserman Wyeth
Abstract Background For genes that have been successfully delineated within the human genome sequence, most regulatory sequences remain to be elucidated. The annotation and interpretation process...