Florian Markowetz, Lutz Edler, Martin Vingron
Abstract: Knowledge of the three-dimensional structure of a protein is essential for describing and understanding its function. Today, a large number of known protein sequences faces a small number...
Schwake, Lukas, Streit, Judith, Edler, Lutz, Encke, Jens, Stremmel, Wolfgang, Junghanss, Thomas
Abstract Introduction Imported falciparum malaria is characterized by a broad spectrum of potentially life-threatening complications that may arise even after initiation of appropriate antimalarial...
Combs, Stephanie E, Heeger, Steffen, Haselmann, Renate, Edler, Lutz, Debus, Jürgen, Schulz-Ertner, Daniela
Abstract Background The implementation of combined radiochemotherapy (RCHT) with temozolomide (TMZ) has lead to a significant increase in overall survival times in patients with Glioblastoma...
Zhang, Chengwen, Kolb, Armin, Büchler, Peter, Cato, Andrew CB, Mattern, Jürgen, Rittgen, Werner, ...
Abstract Background Chemotherapy for pancreatic carcinoma often has severe side effects that limit its efficacy. The glucocorticoid (GC) dexamethasone (DEX) is frequently used as co-treatment to...
Computational statistics and biometry: which discipline drives which? (2005)
A biometrician's work is defined through the biological or medical problem and the mathematical and statistical methods needed for its solution. This requires in most instances statistical data...
Popanda, Odilia, Schattenberg, Torsten, Phong, Chi Tai, Butkiewicz, Dorota, Risch, Angela, Edler, Lutz, ...
Several polymorphisms in DNA repair genes have been reported to be associated with lung cancer risk including XPA (-4G/A), XPD (Lys751Gln and Asp312Asn), XRCC1 (Arg399Gln), APE1 (Asp148Glu), and...
Popanda, Odilia, Schattenberg, Torsten, Phong, Chi Tai, Butkiewicz, Dorota, Risch, Angela, Edler, Lutz, ...
Several polymorphisms in DNA repair genes have been reported to be associated with lung cancer risk including XPA (−4G/A), XPD (Lys751Gln and Asp312Asn), XRCC1 (Arg399Gln), APE1 (Asp148Glu) and...
Support vector machines for protein fold class prediction (2003)
Markowetz,Florian, Edler,Lutz, Vingron,Martin
Knowledge of the three-dimensional structure of a protein is essential for describing and understanding its function. Today, a large number of known protein sequences faces a small number of...
Support vector machines for protein fold class prediction (2003)
Markowetz, Florian, Edler, Lutz, Vingron, Martin
Knowledge of the three-dimensional structure of a protein is essential for describing and understanding its function. Today, a large number of known protein sequences faces a small number of...
Normalisation of gene-expression data 13 (2001)
Biometric Society, Anne Whitehead, Lutz Edler, Hans-peter Piepho, Astrid Dempfle, Sabine Loesgen, ...
Some approaches for mapping quqantitative trait loci (QTL) in plant breeding populations 12
DNA of adeno-associated virus (AAV) in testicular tissue and in abnormal semen samples (2001)
Erles, Kerstin, Rohde, Volker, Thaele, Michael, Roth, Susanne, Edler, Lutz, Schlehofer, Jörg R.
BACKGROUND: Human genital tissues, including spermatozoa, have been found to be frequently infected with the helper-virus dependent parvovirus, adeno-associated virus (AAV). METHODS: To assess the...
Frei, Eva, Gilberg, Frank, Schröder, Manuela, Breuer, Andrea, Edler, Lutz, Wiessler, Manfred
N-nitro-dimethylamine (NTDMA) is carcinogenic to rats: it induces nasal cavity tumours. It can be demethylated to N-nitromethylamine and formaldehyde and reduced to N-nitroso-dimethylamine (NDMA): a...
Two-Stage Models of Carcinogenesis, Classification of Agents, and Design of Experiments (1990)
PORTIER, CHRISTOPHER J., EDLER, LUTZ
Two-Stage Models of Carcinogenesis, Gassification of Agents, and Design of Experiments. PORTIER, C. J., AND EDLER, L. (1990). Fundam. Appl. Toxicol, 14, 444–460. The implications of a clonal...
Schweizer, Jürgen, Loehrke, Heinz, Edler, Lutz, Goerttler, Klaus
A two-stage carcinogenesis experiment was performed in Syrian golden hamsters using a single intragastric initiation with 10 mg/kg body weight of 7,12-dimethylbenz[a]anthracene (DMBA) and repetitive...
Zhang, Chengwen, Kolb, Armin, Büchler, Peter, Cato, Andrew CB, Mattern, Jürgen, Rittgen, Werner, ...
Combs, Stephanie E, Heeger, Steffen, Haselmann, Renate, Edler, Lutz, Debus, Jürgen, Schulz-Ertner, Daniela
Zhang, Chengwen, Kolb, Armin, Büchler, Peter, Cato, Andrew CB, Mattern, Jürgen, Rittgen, Werner, ...
Combs, Stephanie E, Heeger, Steffen, Haselmann, Renate, Edler, Lutz, Debus, Jürgen, Schulz-Ertner, Daniela
Laack, Eckart, Nikbakht, Haleh, Peters, Anja, Kugler, Christian, Jasiewicz, Yvonne, Edler, Lutz, ...
The worldwide incidence of adenocarcinoma of the lung is rising. Unfortunately, no significant prognostic marker beyond the classical TNM staging exists to stratify these patients for appropriate...
Schwake, Lukas, Streit, Judith Pamela, Edler, Lutz, Encke, Jens, Stremmel, Wolfgang, Junghanss, Thomas
Computational statistics within clinical research
Edler, Lutz, Lee, Jae Won, Mittlböck, Martina, Niland, Joyce, Victor, Norbert
Fluctuation behavior of Poisson triangular arrays
The fluctuation behavior of the row sums in a triangular array of Poisson distributed random variables is described by the law of the iterated logarithm under two different assumptions of...
Hoensch, Harald, Groh, Bertram, Edler, Lutz, Kirch, Wilhelm
AIM: To investigate biological prevention with flavonoids the recurrence risk of neoplasia was studied in patients with resected colorectal cancer and after adenoma polypectomy.