Rearrangement and expression of rabbit immunoglobulin kappa light chain gene in transgenic mice.
Goodhardt, M, Cavelier, P, Akimenko, M A, Lutfalla, G, Babinet, C, Rougeon, F
To determine whether a foreign unrearranged immunoglobulin gene can be functionally rearranged and expressed in vivo, a rabbit b9 kappa light chain gene construct containing a single germ-line kappa...
Mariame, B, Akimenko, M A, Rougeon, F
Contrary to the situation in humans or mice, where the constant region (C) of the Immunoglobulin (Ig) kappa (kappa) light chain is encoded by a single gene, the rabbit possesses two C kappa genes: C...
Akimenko, M A, Ekker, M, Doyen, N, Biben, C, Rougeon, F
Enhancer activity of the rabbit immunoglobulin kappa light chain gene intron conserved region (KICR) was examined in mouse myeloma cells using transient expression experiments. Compared to the...
Complex allotypes of the rabbit immunoglobulin kappa light chains are encoded by structural alleles.
Akimenko, M A, Heidmann, O, Rougeon, F
We have isolated the rabbit immunoglobulin b9 Ck light chain gene and compared its nucleotide sequence with the b4, b4var , b5 and bas Ck sequences. In spite of the high number of substitutions found...
Akimenko, M A, Mariamé, B, Rougeon, F
The rabbit kappa light chain gene family is characterized by the presence of two constant region (C kappa) genes; the C kappa 1 gene encodes the constant region of the principal rabbit immunoglobulin...
Rearrangement and expression of rabbit immunoglobulin kappa light chain gene in transgenic mice.
Goodhardt, M, Cavelier, P, Akimenko, M A, Lutfalla, G, Babinet, C, Rougeon, F
To determine whether a foreign unrearranged immunoglobulin gene can be functionally rearranged and expressed in vivo, a rabbit b9 kappa light chain gene construct containing a single germ-line kappa...
Mariame, B, Akimenko, M A, Rougeon, F
Contrary to the situation in humans or mice, where the constant region (C) of the Immunoglobulin (Ig) kappa (kappa) light chain is encoded by a single gene, the rabbit possesses two C kappa genes: C...
Akimenko, M A, Ekker, M, Doyen, N, Biben, C, Rougeon, F
Enhancer activity of the rabbit immunoglobulin kappa light chain gene intron conserved region (KICR) was examined in mouse myeloma cells using transient expression experiments. Compared to the...
Complex allotypes of the rabbit immunoglobulin kappa light chains are encoded by structural alleles.
Akimenko, M A, Heidmann, O, Rougeon, F
We have isolated the rabbit immunoglobulin b9 Ck light chain gene and compared its nucleotide sequence with the b4, b4var , b5 and bas Ck sequences. In spite of the high number of substitutions found...
Akimenko, M A, Mariamé, B, Rougeon, F
The rabbit kappa light chain gene family is characterized by the presence of two constant region (C kappa) genes; the C kappa 1 gene encodes the constant region of the principal rabbit immunoglobulin...