M. Akiyama

Details der Publikationsliste

Zeitraum

1992 - 9999

Anzahl

90

Co-Autoren

MOIRCS Deep Survey IV: Evolution of Galaxy Stellar Mass Function Back to z ~ 3 (2009)

Kajisawa, M., Ichikawa, T., Tanaka, I., Konishi, M., Yamada, T., Akiyama, M., ...

We use very deep near-infrared (NIR) imaging data obtained in MOIRCS Deep Survey (MODS) to investigate the evolution of the galaxy stellar mass function back to z~3. The MODS data reach J=24.2,...

MOIRCS Deep Survey III: Active Galactic Nuclei in Massive Galaxies at z=2-4 (2009)

Yamada, T., Kajisawa, M., Akiyama, M., Ichikawa, T., Konishi, M., Nishimura, T., ...

We investigate the X-ray properties of the K-band-selected galaxies at redshift 2 < z < 4 by using our deep near-infrared images obtained in the MOIRCS Deep Survey project and the published Chandra...

Discovery of a Giant Lyα Emitter Near the Reionization Epoch. (2009)

Ouchi, M., Ono, Y., Egami, E., Saito, T., Oguri, M., McCarthy, P.J., ...

Original article can be found at: http://www.iop.org/EJ/journal/ap Copyright American Astronomical Society. DOI: 10.1088/0004-637X/696/2/1164 [Full text of this article is not available in the UHRA]

Evidence of a link between the evolution of clusters and their AGN fraction. (2009)

Van Breukelen, C., Simpson, C., Rawlings, S., Akiyama, M., Bonfield, D., Clewley, L., ...

‘The definitive version is available at www3.interscience.wiley.com .' Copyright Blackwell Publishing / Royal Astronomical Society. DOI: 10.1111/j.1365-2966.2009.14513.x

An extreme EXO: a type 2 QSO at z=1.87 (2008)

Del Moro, A., Watson, M. G., Mateos, S., Akiyama, M., Hashimoto, Y., Tamura, N., ...

We aim to understand the multi-wavelength properties of 2XMM J123204+215255, the source with the most extreme X-ray-to-optical flux ratio amongst a sample of bright X-ray selected EXOs drawn from a...

Evolution of Star-forming Galaxies seen from Lyman Break Galaxies at $z\sim5$ (2008)

Ohta, K., Yabe, K., Iwata, I., Sawicki, M., Akiyama, M., Tamura, N., ...

Properties of Lyman Break Galaxies at $z\sim5$ are presented and are compared with those at $z\sim 2-3$ LBGs to see evolution of LBGs from $z\sim5$ to $z \sim3-2$. The LBGs at $z\sim5$ are tend to...

A Pilot Survey for KX QSOs in the UKIDSS Ultra Deep Survey Field (2008)

Smail, Ian, Sharp, Rob, Swinbank, A. M., Akiyama, M., Ueda, Y., Foucaud, S., ...

We have undertaken a pilot survey for faint QSOs in the UKIDSS Ultra Deep Survey Field using the KX selection technique. These observations exploit the very deep near-infrared and optical imaging of...

Detections of Lyman Continuum from Star-forming Galaxies at z~3 Through Subaru/Suprime-Cam Narrow-band Imaging (2008)

Iwata, I., Inoue, A. K., Matsuda, Y., Furusawa, H., Hayashino, T., Kousai, K., ...

Knowing the amount of ionizing photons from young star-forming galaxies is of particular importance to understanding the reionization process. Here we report initial results of Subaru/Suprime-Cam...

The Subaru/XMM-Newton Deep Survey (SXDS) - II. Optical Imaging and Photometric Catalogs (2008)

Furusawa, H., Kosugi, G., Akiyama, M., Takata, T., Sekiguchi, K., Tanaka, I., ...

We present multi-waveband optical imaging data obtained from observations of the Subaru/XMM-Newton Deep Survey (SXDS). The survey field, centered at R.A.=02:18:00, decl.=-05:00:00, has been the focus...

Lithium Ion capacitor characterization and modelling (2008)

Gualous, Hamid, Alcicek, G., Diab, Yasser, Hammar, A., Venet, Pascal, Adams, K., ...

To develop electrical busses for applications with a fast recharge system in stations, PVI has been testing some electrical energy components like supercapacitors and batteries with high power...

Lithium Ion capacitor characterization and modelling (2008)

Gualous, Hamid, Alcicek, G., Diab, Yasser, Hammar, A., Venet, Pascal, Adams, K., ...

To develop electrical busses for applications with a fast recharge system in stations, PVI has been testing some electrical energy components like supercapacitors and batteries with high power...

Adaptive Optics Imaging of Lyman Break Galaxies as Progenitors of Spheroids in the Local Universe (2007)

Akiyama, M., Minowa, Y., Kobayashi, N., Ohta, K., Iwata, I.

In order to reveal the stellar mass distribution of z~3 galaxies, we are conducting deep imaging observations of U-dropout Lyman Break Galaxies (LBGs) with Adaptive Optics (AO) systems in K-band,...

Adaptive Optics Rest-Frame V-band Imaging of Lyman Break Galaxies at z~3: High-surface Density Disk-like Galaxies ? (2007)

Akiyama, M., Minowa, Y., Kobayashi, N., Ohta, K., Ando, M., Iwata, I.

In order to reveal the rest-frame V-band morphology of galaxies at z~3, we conducted AO-assisted K-band imaging observations of z~3 LBGs with Mv*-0.5 to Mv*+3.0 mag. LBGs brighter than Mv* have...

Differential Evolution of the UV Luminosity Function of Lyman Break Galaxies from z~5 to 3 (2007)

Iwata, I., Ohta, K., Tamura, N., Akiyama, M., Aoki, K., Ando, M., ...

(abridged) We report the UV luminosity function (LF) of Lyman break galaxies at z~5 derived from a deep and wide survey using the Subaru/Suprime-Cam. Target fields consist of two blank regions of the...

N-Linked neutral oligosaccharides in the stratum corneum of normal and ichthyotic skin (2007)

Ito, H., Akiyama, M., Nakagawa, H., Uematsu, R., Deguchi, K., McMillan, J.R., ...

N-Glycan oligosaccharides are thought to play multiple, important roles in a variety of biological events. However, N-glycan proWles in the stratum corneum of human skin have not yet been studied in...

Plectin defects in epidermolysis bullosa simplex with muscular dystrophy (2007)

McMillan, J. R., Akiyama, M., Rouan, F., Mellerio, J. E., Lane, E. B., Leigh, I. M., ...

Epidermolysis bullosa simplex with muscular dystrophy (EBS-MD, MIM 226670) is caused by plectin defects. We performed mutational analysis and immunohistochemistry using EBS-MD (n 3 cases) and control...

A novel GJB2 mutation p.Asn54His in a patient with palmoplantar keratoderma, sensorineural hearing loss and knuckle pads (2007)

Akiyama, M., Sakai, K., Arita, K., Nomura, Y., Ito, K., Kodama, K., ...

Mutations in the GJB2 gene encoding connexin26 are the major cause of autosomal-recessive or -dominant nonsyndromic congenital sensorineural hearing loss (SNHL) (Kelsell et al., 1997; Kenneson et...

Balmer Absorption Lines in FeLoBALs (2006)

Aoki, K., Iwata, I., Ohta, K., Tamura, N., Ando, M., Akiyama, M., ...

We discovered non-stellar Balmer absorption lines in two many-narrow-trough FeLoBALs (mntBALs) by the near-infrared spectroscopy with Subaru/CISCO. Presence of the non-stellar Balmer absorption lines...

Luminosity Dependent Evolution of Lyman Break Galaxies from redshift 5 to 3 (2006)

Iwata, I., Ohta, K., Tamura, N., Akiyama, M., Aoki, K., Ando, M., ...

In this contribution we briefly describe our recent results on the properties of Lyman break galaxies at z~5 obtained from deep and wide blank field surveys using Subaru telescope, and through the...

Childhood epidermolysis bullosa acquisita with autoantibodies against the noncollagenous 1 and 2 domains of type VII collagen : case report and review of the literature (2006)

Mayuzumi, M., Akiyama, M., Nishie, W., Ukae, S., Abe, M., Sawamura, D., ...

Epidermolysis bullosa acquisita (EBA) is an acquired subepidermal bullous disease characterized by IgG autoantibodies to type VII collagen, a major component of anchoring fibrils. Most patients with...

PDGF isoforms induce and maintain anagen phase of murine hair follicles (2006)

Tomita, Y., Akiyama, M., Shimizu, H.

Background : It is known that platelet-derived growth factor (PDGF) receptors are expressed in hair follicle (HF) epithelium. Objectives : The aim of the present study was to clarify the effects of...

PDGF isoforms induce and maintain anagen phase of murine hair follicles. (2006)

Tomita, Y., Akiyama, M., Shimizu, H.

Background : It is known that platelet-derived growth factor (PDGF) receptors are expressed in hair follicle (HF) epithelium.

PDGF isoforms induce and maintain anagen phase of murine hair follicles. (2006)

Tomita, Y., Akiyama, M., Shimizu, H.

Background : It is known that platelet-derived growth factor (PDGF) receptors are expressed in hair follicle (HF) epithelium.

An X-ray bright ERO hosting a type 2 QSO (2006)

Severgnini, P., Caccianiga, A., Braito, V., Della Ceca, R., Maccacaro, T., Akiyama, M., ...

We present the XMM-Newton and the optical-VLT spectra along with the optical and the near-infrared photometric data of one of the brightest X-ray (F(2-10 keV)~1e-13 erg/s cm^2) extremely red objects...

A Novel ABCA12 Mutation 3270delT Causes Harlequin Ichthyosis (2006)

Akiyama, M., Sakai, K., Wolff, G., Hausser, J. R., McMillan, J. R., Sawamura, D., ...

The article presents a case of a baby girl who had been suffering from harlequin ichthyosis, a severe fatal congenital ichthyosis. Its clinical features include thick, plate-like scales with...

Evolution of Lyman Break Galaxies From z=5 to 3 (2005)

Iwata, I., Ohta, K., Ando, M., Kiuchi, G., Tamura, N., Akiyama, M., ...

We report the updated UV luminosity function (LF) of Lyman break galaxies (LBGs) at z~5. Combining with lower redshift data, we found that the evolution of UV LF is differential depending on the UV...

Deep Spectroscopic Survey of Lyman Break Galaxies at z~5 (2005)

Ando, M., Ohta, K., Iwata, I., Akiyama, M., Aoki, K., Tamura, N.

We report results of deep optical spectroscopy with Subaru/FOCAS for Lyman Break Galaxy (LBG) candidates at z~5. So far, we made spectroscopic observations for 24 LBG candidates among ~200 bright...

Definitive Identification of the Transition between Small- to Large-Scale Clustering for Lyman Break Galaxies (2005)

Ouchi, M, Hamana, T., Shimasaku, K., Yamada, T., Akiyama, M., Kashikawa, N., ...

We report angular correlation function (ACF) of Lyman Break Galaxies (LBGs) with unprecedented statistical quality on the basis of 16,920 LBGs at z=4 detected in the 1 deg^2 sky of the...

Discovery of multiple ultraluminous X-ray sources in the galaxy KUG 0214-057 (2005)

Watson, M. G., Roberts, T. P., Akiyama, M., Ueda, Y.

We report the serendipitous discovery of several unresolved X-ray sources lying in the prominent spiral arms of the galaxy KUG 0214-057 in XMM-Newton observations. The location of these X-ray sources...

SYSTEM STUDY FOR SUPER MOBILE COMMUNICATIONS SATELLITE GROUND STATION. (2005)

HABER,F., Akiyama,M., Feld,J., Harper,R., Moff,R.

The objective of the work described is to investigate the system requirements and to provide the design parameters for a highly transportable communications satellite ground station. The study takes...

SYSTEM STUDY FOR SUPER MOBILE COMMUNICATIONS SATELLITE GROUND STATION. (2005)

Haber,F., Akiyama,M., Ya'Coub,K., Feld,J., Moff,R.

The work included analyses of certain digital modulation systems which are potential competitors to the analog systems reviewed earlier, analysis of antenna noise, further develop ment of antenna...

Beta defensin-3 engineered epidermis shows highly protective effect for bacterial infection (2005)

Sawamura, D., Goto, M., Shibaki, A., Akiyama, M., Mcmillan, J. R., Abiko, Y., ...

Defensins are small cationic proteins that harbor broad-spectrum microbicidal activity against bacteria, fungi and viruses. This study examines the effects on pathogens of the epidermis engineered to...

The Discovery of Primeval Large-Scale Structures with Forming Clusters at Redshift 6 (2004)

Ouchi, M., Shimasaku, K., Akiyama, M., Sekiguchi, K., Furusawa, H., Okamura, S., ...

We report the discovery of primeval large-scale structures (LSSs) including two proto-clusters in a forming phase at z=5.7. We carried out extensive deep narrow-band imaging in the 1 deg^2 sky of the...

The Subaru Deep Field: The Optical Imaging Data (2004)

Kashikawa, N., Shimasaku, K., Yasuda, N., Ajiki, M., Akiyama, M., Ando, H., ...

The Subaru Deep Field (SDF) project is a program of Subaru Observatory to carry out a deep galaxy survey over a blank field as large as 34'x27'. The program consists of very deep multi-band optical...

A Strong Lyman-alpha Emitter at z=6.33 in the Subaru Deep Field Selected as an i' Dropout (2004)

Nagao, T., Taniguchi, Y., Kashikawa, N., Kodaira, K., Kaifu, N., Ando, H., ...

We report on the discovery of a star-forming galaxy at z=6.33 in the Subaru Deep Field. This object is selected as a candidate of an i'-dropout, high-redshift galaxy around z=6 because of its red...

Gap junction development in the human fetal hair follicle and bulge region (2004)

Arita, K., Akiyama, M., Tsuji, Y., Mcmillan, J. R., Eady, R. A. J., Shimizu, H.

Background Gap junctions, composed of connexin (Cx) subunits, are channels that allow intercellular communication between adjacent cells and are thought to play a key role in the regulation of cell...

XMM-Newton observations expose AGN in apparently normal galaxies (2003)

Severgnini, P., Caccianiga, A., Braito, V., Della Ceca, R., Maccacaro, T., Wolter, A., ...

We have performed a detailed analysis of 3 optically normal galaxies extracted from the XMM Bright Serendipitous Source Sample. Thanks to the good statistics of the XMM-Newton data, we have unveiled...

Lyman Break Galaxies at z~5: Luminosity Function (2003)

Iwata, I., Ohta, K., Tamura, N., Ando, M., Wada, S., Watanabe, C., ...

(abridged) We present results of a search for Lyman break galaxies (LBGs) at z ~ 5 in a 618 square-arcmin field including the HDF-N taken by Subaru Prime Focus Camera. Utilizing the published...

The Tungsten-Tungsten Triple Bond. 8.(1) Dinuclear Alkoxides of Tungsten (III) and Structural Characterization of Hexakis-(Isopropoxy)Dipyridinoditungsten. The First Compound with Four-Coordinated Tungsten Atoms United by a Triple Bond. (2002)

Akiyama,M., Chisholm,M. H., Cotton,F. A., Extine,M. W., Haitko,D. A.

The great majority of compounds containing metal-metal triple bonds of the x3mmx3 type where X is a monodentate ligand (including some where the ligand atmos are not all the same) have perfectly, or...

The Tetradecaisopropoxydihydridotetratungsten Story. (2002)

Akiyama,M., Chisholm,M. H., Cotton,F. A., Extine,M. W., Haitko,D. A.

Tetradecaisopropoxydihydridotetratungsten, W4(Mu-H)2 (OPr(i))14, has been isolated from the reaction between W2(NMe2)6 (M identical M) and excess isopropanol and has been characterized by ir, nmr,...

Deep-Imaging Observations of a Candidate of an Absorbed QSO at z=0.653, AX J131831+3341 (2000)

Akiyama, M., Ohta, K., Tamura, N., Doi, M., Kimura, M., Komiyama, Y., ...

The results of deep-imaging observations of a candidate of an absorbed QSO at z=0.653, AX J131831+3341, are presented. AX J131831+3341 was found during the course of optical follow-up observations of...

Optical Identification of the ASCA Large Sky Survey (2000)

Akiyama, M., Ohta, K., Yamada, T., Kashikawa, N., Yagi, M., Kawasaki, W., ...

We present results of optical identification of the X-ray sources detected in the ASCA Large Sky Survey. Optical spectroscopic observations were done for 34 X-ray sources which were detected with the...

Log N - Log S Relations and Spectral Properties of Sources from the ASCA Large Sky Survey --- their Implications for the Origin of the Cosmic X-ray Background (CXB) (1999)

Ueda, Y., Takahashi, T., Inoue, H., Tsuru, T., Sakano, M., Ishisaki, Y., ...

We carried out the first wide-area unbiased survey with the ASCA satellite in the 0.7-10 keV band around a north Galactic-pole region covering a continuous area of 7 square degrees (Large Sky Survey;...

Nature of Hard X-ray Source from Optical Identification of the ASCA Large Sky Survey (1998)

Akiyama, M., Ohta, K., Yamada, T., Ueda, Y., Takahashi, T., Sakano, M., ...

We present results of optical identification of the ASCA Large Sky Survey. X-ray sources which have hard X-ray spectra were identified with type-2 AGN at redshifts smaller than 0.5. It is supported...

Method for Preparing a SiC Whisker-Reinforced Composite Material (1998)

Akiyama,M., Yamada,J., Takahata,M.

The invention provides a method for preparing a SiC whisker-reinforced composite material. A matrix material such as metal, an alloy or a plastic is introduced into a fibrous base consisting of a SiC...

Optical Identification of the Hardest X-ray Source in the ASCA Large Sky Survey (1998)

Akiyama, M., Ohta, K., Yamada, T., Eracleous, M., Halpern, J. P., Kashikawa, N., ...

We report the optical identification of the hardest X-ray source (AX J131501+3141) detected in an unbiased wide-area survey in the 0.5--10 keV band, the ASCA Large Sky Survey. The X-ray spectrum of...

Prandtl number of lattice Bhatnagar-Gross-Krook fluid (1995)

Chen, Y., Ohashi, H., Akiyama, M.

The lattice Bhatnagar-Gross-Krook modeled fluid has an unchangeable unit Prandtl number. A simple method is introduced in this letter to formulate a flexible Prandtl number for the modeled fluid. The...

Prototype Light Angular Deflector and its Diffraction Characteristics (1995)

S. Suzaki, T. Sekiguchi, M. Akiyama, T. Aizawa

this report, we have fabricated prototype LAD and estimated the propagation and diffraction characteristics. 2. Function and Principle The LAD and the operation circuit for generating deflection...

Heat Transfer in Lattice BGK Modeled Fluid (1994)

Chen, Y., Ohashi, H., Akiyama, M.

The thermal lattice BGK model is a recently suggested numerical tool which aims to simulate thermohydrodynamic problems. We investigate the quality of the lattice BGK simulation by calculating the...

Study of Light Angular Deflector (1994)

S. Suzaki, T. Aizawa, M. Akiyama, T. Sekiguchi, K. G. Ravikumar

this report, we will propose the new type 1.3¯m region InGaAsP/InP light angular deflector (LAD). An LAD is one of the passive optical device and is applicable to spatial light signal switching...

Advective surface velocity in the north west Pacific derived from NOAA AVHRR images (1992)

Pankajakshan, T., Akiyama, M., Okada, Y., Sugimori, Y.

Using sequential AVHRR images in November 1983, nearsurface advective velocities are derived in the region Kuroshio south of Japan. For deriving the velocities two methods are used. One is the Method...

Mixed layer heat budget of Kuroshio-Tango Triangle using satellite and ship observations (1992)

Pankajakshan, T., Akiyama, M., Sugimori, Y., Wuwa, J., Okada, Y., Siripong, A.

Using a three dimensional heat flux model, variation of heat storage in the mixed layer of a triangular oceanic area, embedded in the Kuroshio has been studied for a period of a few days in the month...

Virulence of Yersinia pseudotuberculosis isolated from pork and from the throats of swine.

Shiozawa, K, Hayashi, M, Akiyama, M, Nishina, T, Nakatsugawa, S, Fukushima, H, ...

Yersinia pseudotuberculosis was isolated from retail pork and from healthy swine throats. These wild-type strains and their representative cured isogenic strains were tested for the presence of...

Q fever pneumonia in children in Japan.

To, H, Kako, N, Zhang, G Q, Otsuka, H, Ogawa, M, Ochiai, O, ...

The prevalence of Q fever pneumonia among children with atypical pneumonia from whom only an acute-phase serum sample was available was traced by using an indirect immunofluorescence (IF) test,...

Epidemiology of Tsutsugamushi disease in relation to the serotypes of Rickettsia tsutsugamushi isolated from patients, field mice, and unfed chiggers on the eastern slope of Mount Fuji, Shizuoka Prefecture, Japan.

Kawamori, F, Akiyama, M, Sugieda, M, Kanda, T, Akahane, S, Uchikawa, K, ...

A total of 59 strains of Rickettsia tsutsugamushi were isolated from patients (24 isolates), Apodemus speciosus mice (30 isolates), and unfed larvae of Leptotrombidium scutellare (2 isolates) and...

A specific role of MutT protein: to prevent dG.dA mispairing in DNA replication.

Akiyama, M, Maki, H, Sekiguchi, M, Horiuchi, T

Occurrence of the transversion mutation A.T to C.G is specifically enhanced in Escherichia coli mutT mutants. With the aid of the cloned mutT gene, the MutT protein, which has a molecular mass of 15...

Rapid change in mutation rate in a local population of Drosophila melanogaster.

Mukai, T, Baba, M, Akiyama, M, Uowaki, N, Kusakabe, S, Tajima, F

The lethal and detrimental loads per second chromosome rapidly increased from 1968 to 1970 in a local population of Drosophila melanogaster in Japan (lethal load, from about 0.16 to 0.38; detrimental...

Thermotropic phase properties of 1,2-di-O-tetradecyl-3-O-(3-O-methyl- beta-D-glucopyranosyl)-sn-glycerol.

Trouard, T P, Mannock, D A, Lindblom, G, Rilfors, L, Akiyama, M, McElhaney, R N

The hydration properties and the phase structure of 1,2-di-O-tetradecyl-3-O(3-O-methyl-beta-D-glucopyranosyl)-sn-glycerol (3-O-Me-beta-D-GlcDAIG) in water have been studied via differential scanning...

Effect of the chirality of the glycerol backbone on the bilayer and nonbilayer phase transitions in the diastereomers of di-dodecyl-beta-D-glucopyranosyl glycerol.

Mannock, D A, Lewis, R N, McElhaney, R N, Akiyama, M, Yamada, H, Turner, D C, ...

We have studied the physical properties of aqueous dispersions of 1,2-sn- and 2,3-sn-didodecyl-beta-D-glucopyranosyl glycerols, as well as their diastereomeric mixture, using differential scanning...

A novel blocker-PCR method for detection of rare mutant alleles in the presence of an excess amount of normal DNA.

Seyama, T, Ito, T, Hayashi, T, Mizuno, T, Nakamura, N, Akiyama, M

A novel polymerase chain reaction method was developed to preferentially amplify a segment of DNA containing a base substitution mutation. This technique uses a pair of dideoxynucleotide-labeled...

Monitoring exposure to atomic bomb radiation by somatic mutation.

Akiyama, M, Kyoizumi, S, Kusunoki, Y, Hirai, Y, Tanabe, K, Cologne, J B

Atomic bomb survivors are a population suitable for studying the relationship between somatic mutation and cancer risk because their exposure doses are relatively well known and their dose responses...

Talc and amosite/crocidolite preferentially deposited in the lungs of nonoccupational female lung cancer cases in urban areas of Japan.

Yamada, H, Hashimoto, H, Akiyama, M, Kawabata, Y, Iwai, K

To analyze the correlation between asbestos lung burden and lung cancer, lungs of 211 female cases with and without lung cancer were examined. Phase-contrast microscopic (PCM) counting of ferruginous...

Virulence of Yersinia pseudotuberculosis isolated from pork and from the throats of swine.

Shiozawa, K, Hayashi, M, Akiyama, M, Nishina, T, Nakatsugawa, S, Fukushima, H, ...

Yersinia pseudotuberculosis was isolated from retail pork and from healthy swine throats. These wild-type strains and their representative cured isogenic strains were tested for the presence of...

Q fever pneumonia in children in Japan.

To, H, Kako, N, Zhang, G Q, Otsuka, H, Ogawa, M, Ochiai, O, ...

The prevalence of Q fever pneumonia among children with atypical pneumonia from whom only an acute-phase serum sample was available was traced by using an indirect immunofluorescence (IF) test,...

Epidemiology of Tsutsugamushi disease in relation to the serotypes of Rickettsia tsutsugamushi isolated from patients, field mice, and unfed chiggers on the eastern slope of Mount Fuji, Shizuoka Prefecture, Japan.

Kawamori, F, Akiyama, M, Sugieda, M, Kanda, T, Akahane, S, Uchikawa, K, ...

A total of 59 strains of Rickettsia tsutsugamushi were isolated from patients (24 isolates), Apodemus speciosus mice (30 isolates), and unfed larvae of Leptotrombidium scutellare (2 isolates) and...

A specific role of MutT protein: to prevent dG.dA mispairing in DNA replication.

Akiyama, M, Maki, H, Sekiguchi, M, Horiuchi, T

Occurrence of the transversion mutation A.T to C.G is specifically enhanced in Escherichia coli mutT mutants. With the aid of the cloned mutT gene, the MutT protein, which has a molecular mass of 15...

A novel blocker-PCR method for detection of rare mutant alleles in the presence of an excess amount of normal DNA.

Seyama, T, Ito, T, Hayashi, T, Mizuno, T, Nakamura, N, Akiyama, M

A novel polymerase chain reaction method was developed to preferentially amplify a segment of DNA containing a base substitution mutation. This technique uses a pair of dideoxynucleotide-labeled...

Rapid change in mutation rate in a local population of Drosophila melanogaster.

Mukai, T, Baba, M, Akiyama, M, Uowaki, N, Kusakabe, S, Tajima, F

The lethal and detrimental loads per second chromosome rapidly increased from 1968 to 1970 in a local population of Drosophila melanogaster in Japan (lethal load, from about 0.16 to 0.38; detrimental...

Thermotropic phase properties of 1,2-di-O-tetradecyl-3-O-(3-O-methyl- beta-D-glucopyranosyl)-sn-glycerol.

Trouard, T P, Mannock, D A, Lindblom, G, Rilfors, L, Akiyama, M, McElhaney, R N

The hydration properties and the phase structure of 1,2-di-O-tetradecyl-3-O(3-O-methyl-beta-D-glucopyranosyl)-sn-glycerol (3-O-Me-beta-D-GlcDAIG) in water have been studied via differential scanning...

Effect of the chirality of the glycerol backbone on the bilayer and nonbilayer phase transitions in the diastereomers of di-dodecyl-beta-D-glucopyranosyl glycerol.

Mannock, D A, Lewis, R N, McElhaney, R N, Akiyama, M, Yamada, H, Turner, D C, ...

We have studied the physical properties of aqueous dispersions of 1,2-sn- and 2,3-sn-didodecyl-beta-D-glucopyranosyl glycerols, as well as their diastereomeric mixture, using differential scanning...

Monitoring exposure to atomic bomb radiation by somatic mutation.

Akiyama, M, Kyoizumi, S, Kusunoki, Y, Hirai, Y, Tanabe, K, Cologne, J B

Atomic bomb survivors are a population suitable for studying the relationship between somatic mutation and cancer risk because their exposure doses are relatively well known and their dose responses...

Talc and amosite/crocidolite preferentially deposited in the lungs of nonoccupational female lung cancer cases in urban areas of Japan.

Yamada, H, Hashimoto, H, Akiyama, M, Kawabata, Y, Iwai, K

To analyze the correlation between asbestos lung burden and lung cancer, lungs of 211 female cases with and without lung cancer were examined. Phase-contrast microscopic (PCM) counting of ferruginous...

Feasibility of using decades-old archival tissues in molecular oncology/epidemiology.

Iwamoto, K. S., Mizuno, T., Ito, T., Akiyama, M., Takeichi, N., Mabuchi, K., ...

Archival tissues are a bountiful resource for various studies. Polymerase chain reaction permits the use of such tissues for molecular biological analyses of disease causation. However, a...

Dexamethasone impairs pulmonary defence against Pseudomonas aeruginosa through suppressing iNOS gene expression and peroxynitrite production in mice

Satoh, S, Oishi, K, Iwagaki, A, Senba, M, Akaike, T, Akiyama, M, ...

To elucidate the in vivo mechanisms involved in the impairment in pulmonary defence as the result of treatment with glucocorticoids, we established fatal pneumonia with bacteraemia in dexamethasone...

Potentiating action of MKC-242, a selective 5-HT1A receptor agonist, on the photic entrainment of the circadian activity rhythm in hamsters

Moriya, T, Yoshinobu, Y, Ikeda, M, Yokota, S, Akiyama, M, Shibata, S

Serotonergic projections from the midbrain raphe nuclei to the suprachiasmatic nuclei (SCN) are known to regulate the photic entrainment of circadian clocks. However, it is not known which...

Restoration of p16INK4A protein induces myogenic differentiation in RD rhabdomyosarcoma cells

Urashima, M, Teoh, G, Akiyama, M, Yuza, Y, Anderson, K C, Maekawa, K

p16INK4A (p16) tumour suppressor induces growth arrest by inhibiting function of cyclin-dependent kinase (CDK)4 and CDK6. Homozygous p16 gene deletion is frequent in primary rhabdomyosarcoma (RMS)...