M. D. Perng

The Alexander disease-causing Glial Fibrillary Acidic Protein mutant, R416W, accumulates into Rosenthal fibers by a pathway that involves filament aggregation and the association of alphaB-crystallin and HSP27. (2006)

Perng, M. D., Su, M., Wen, S. F., Li, R., Gibbon, T., Prescott, A. R., ...

Here, we describe the early events in the disease pathogenesis of Alexander disease. This is a rare and usually fatal neurodegenerative disorder whose pathological hallmark is the abundance of...

R120G alphaB-crystallin promotes the unfolding of reduced alpha-lactalbumin and is inherently unstable (2005)

Treweek, T. M., Rekas, A., Lindner, R. A., Walker, M. J., Aquilina, J. A., Robinson, C. V., ...

The definitive version is available at www.blackwell-synergy.com

R120G alphaB-crystallin promotes the unfolding of reduced alpha-lactalbumin and is inherently unstable (2005)

Treweek, T. M., Rekas, A., Lindner, R. A., Walker, M. J., Aquilina, J. A., Robinson, C. V., ...

The definitive version is available at www.blackwell-synergy.com

R120G alphaB-crystallin promotes the unfolding of reduced alpha-lactalbumin and is inherently unstable (2005)

Treweek, T. M., Rekas, Agata, Lindner, Robyn A., Walker, M. J., Aquilina, J. Andrew, Robinson, Carol V., ...

The definitive version is available at www.blackwell-synergy.com

Desmin aggregate formation by R120G alpha B-crystallin is caused byaltered filament interactions and is dependent upon network status in cells. (2004)

Perng, M. D., Wen, S. F., Van Den Ijssel, P., Prescott, A. R., Quinlan, R. A.

The R120G mutation in alphaB-crystallin causes desmin-related myopathy. There have been a number of mechanisms proposed to explain the disease process, from altered protein processing to loss of...

The intermediate filament systems in the eye lens. (2004)

Perng,M.D., Sandilands,A., Kuszak,J., Dahm,Ralf, Wegener,A., Prescott,A.R., ...

The intermediate filament systems in the eye lens. (2004)

Perng, M.D., Sandilands, A., Kuszak, J., Dahm, Ralf, Wegener, A., Prescott, A.R., ...