N.R. Chu, H.B. Wu, T.-C. Wu, L.J. Boux, L.A. Mizzen, M.I. Siegel
Saltiel, A R, Siegel, M I, Jacobs, S, Cuatrecasas, P
Recent evidence suggests that certain actions of insulin may be mediated by the selective generation of chemically undefined intracellular substances. Incubation of rat liver particulate fraction...
Siegel, M I, McConnell, R T, Porter, N A, Cuatrecasas, P
The enzymes of arachidonate metabolism via the lipoxygenase pathway in human platelet cytosol have been characterized and partially purified. The lipoxygenase activity has a pH optimum of 7.3 and...
Siegel, M I, McConnell, R T, Cuatrecasas, P
Aspirin, indomethacin, and sodium salicylate are anti-inflammatory, analgesic, and antipyretic. Whereas aspirin and indomethacin inhibit prostaglandin synthetase (cyclo-oxygenase;...
Action of corticosteroids in regulation of prostaglandin biosynthesis in cultured fibroblasts.
Chandrabose, K A, Lapetina, E G, Schmitges, C J, Siegel, M I, Cuatrecasas, P
Various vasoactive agents (e.g., thrombin and bradykinin) and serum stimulate arachidonate production and thus prostaglandin biosynthesis in cultured fibroblasts. Treatment of 3T3 cells with the...
Anthes, J C, Zhan, Z, Gilchrest, H, Egan, R W, Siegel, M I, Billah, M M
The effects of interferon-alpha (IFN-alpha) on the interleukin-6 (IL-6) receptor in a multiple myeloma cell line, U266, have been examined. IFN-alpha inhibits [3H]thymidine incorporation in U266...
Antigen-stimulated metabolism of inositol phospholipids in the cloned murine mast-cell line MC9.
Cells of the murine mast-cell clone MC9 grown in suspension culture were sensitized with an anti-DNP (dinitrophenol) IgE and subsequently prelabelled by incubating with [32P]Pi. Stimulation of these...
Chu, N.R., Wu, H.B., Wu, T.-C., Boux, L.J., Mizzen, L.A., Siegel, M.I.
Human papillomavirus type 16 (HPV16) infection has been linked to the development of cervical and anal dysplasia and cancer. One hallmark of persistent infection is the synthesis of the viral E7...
Smith, T D, Siegel, M I, Bhatnagar, K P
Adult primates have at least five known phenotypes of vomeronasal organ (VNO), ranging from the typical morphology seen in most other mammals to complete absence. With such morphological disparity,...
Chu, N.R., Wu, H.B., Wu, T.-C., Boux, L.J., Mizzen, L.A., Siegel, M.I.
Human papillomavirus type 16 (HPV16) infection has been linked to the development of cervical and anal dysplasia and cancer. One hallmark of persistent infection is the synthesis of the viral E7...
Saltiel, A R, Siegel, M I, Jacobs, S, Cuatrecasas, P
Recent evidence suggests that certain actions of insulin may be mediated by the selective generation of chemically undefined intracellular substances. Incubation of rat liver particulate fraction...
Siegel, M I, McConnell, R T, Porter, N A, Cuatrecasas, P
The enzymes of arachidonate metabolism via the lipoxygenase pathway in human platelet cytosol have been characterized and partially purified. The lipoxygenase activity has a pH optimum of 7.3 and...
Siegel, M I, McConnell, R T, Cuatrecasas, P
Aspirin, indomethacin, and sodium salicylate are anti-inflammatory, analgesic, and antipyretic. Whereas aspirin and indomethacin inhibit prostaglandin synthetase (cyclo-oxygenase;...
Action of corticosteroids in regulation of prostaglandin biosynthesis in cultured fibroblasts.
Chandrabose, K A, Lapetina, E G, Schmitges, C J, Siegel, M I, Cuatrecasas, P
Various vasoactive agents (e.g., thrombin and bradykinin) and serum stimulate arachidonate production and thus prostaglandin biosynthesis in cultured fibroblasts. Treatment of 3T3 cells with the...
Anthes, J C, Zhan, Z, Gilchrest, H, Egan, R W, Siegel, M I, Billah, M M
The effects of interferon-alpha (IFN-alpha) on the interleukin-6 (IL-6) receptor in a multiple myeloma cell line, U266, have been examined. IFN-alpha inhibits [3H]thymidine incorporation in U266...
Antigen-stimulated metabolism of inositol phospholipids in the cloned murine mast-cell line MC9.
Cells of the murine mast-cell clone MC9 grown in suspension culture were sensitized with an anti-DNP (dinitrophenol) IgE and subsequently prelabelled by incubating with [32P]Pi. Stimulation of these...
Smith, T D, Siegel, M I, Bhatnagar, K P
Adult primates have at least five known phenotypes of vomeronasal organ (VNO), ranging from the typical morphology seen in most other mammals to complete absence. With such morphological disparity,...
Chu, N R, Wu, H B, Wu, T-C, Boux, L J, Siegel, M I, Mizzen, L A
Human papillomavirus type 16 (HPV16) infection has been linked to the development of cervical and anal dysplasia and cancer. One hallmark of persistent infection is the synthesis of the viral E7...
Antitussive effects of GABAB agonists in the cat and guinea-pig.
Bolser, D. C., Aziz, S. M., DeGennaro, F. C., Kreutner, W., Egan, R. W., Siegel, M. I., ...
1. GABAB agonists inhibit neuronal processes which are important in the pathogenesis of airway disease, such as bronchospasm. Cough is a prominent symptom of pulmonary disease, but the effects of...