M. J. Jager

Details der Publikationsliste

Zeitraum

1988 - 2007

Anzahl

27

Co-Autoren

Vascular endothelial growth factor A in eyes with uveal melanoma (2006)

Missotten, G.S.O., Notting, I.C., Schlingemann, R.O., Zijlmans, H.J., Lau, C., Eilers, P.H.C., ...

Objectives: To determine the presence of vascular endothelial growth factor A (VEGF-A) in the aqueous humor of eyes with uveal melanoma and to identify its source. Methods: The VEGF-A concentrations...

Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS (2005)

Zuidervaart, W., Van Nieuwpoort, F., Stark, M., Dijkman, R., Packer, L., ...

In contrast to cutaneous melanoma, there is no evidence that BRAF mutations are involved in the activation of the mitogen-activated protein kinase (MAPK) pathway in uveal melanoma, although there is...

Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS (2005)

Zuidervaart, W., Van Nieuwpoort, F., Stark, M., Dijkman, R., Packer, L., ...

In contrast to cutaneous melanoma, there is no evidence that BRAF mutations are involved in the activation of the mitogen-activated protein kinase (MAPK) pathway in uveal melanoma, although there is...

In vitro effect of (3-amino-1-hydroxypropylidene)-1,1-bisphosphonic acid (APD) on the function of mononuclear phagocytes in lymphocyte proliferation.

De Vries, E, Van Der Weij, J P, Van Der Veen, C J, Van Paassen, H C, Jager, M J, Sleeboom, H P, ...

The effect of (3-amino-1-hydroxypropylidene)-1,1-bisphosphonic acid (APD) on pokeweed mitogen-stimulated and non-stimulated cultures of peripheral blood mononuclear cells was studied in vitro. It is...

Possibilities and limitations of radioimmunoscintigraphy and conventional diagnostic modalities in choroidal melanoma.

Schaling, D F, Oosterhuis, J A, Jager, M J, Kakebeeke-Kemme, H, Pauwels, E K

A prospective clinical study to assess the value of immunoscintigraphy with a monoclonal antibody (MoAb) against high molecular weight melanoma associated antigen (225.28S) was performed in 43...

Genetic and clinical determinants for the T cell mediated immune response against the cornea specific protein BCP 54.

Jager, M J, Völker-Dieben, H J, De Waal, L, Kok, F G, Broersma, L

T cell mediated immune responses against the cornea specific protein BCP 54 have been observed in patients with uveitis, Fuchs' heterochromic cyclitis, and corneal disease. The pathophysiological...

Effects of interferon alfa and gamma on human uveal melanoma cells in vitro.

Creyghton, W M, Kool, J, Jager, M J

BACKGROUND--Uveal melanoma is a tumour with a high incidence of metastasis and a high mortality rate. Additional therapies to obtain a better local control or an effective treatment of metastases are...

Radioimmunoscintigraphy and immunohistochemistry with melanoma-associated monoclonal antibodies in choroidal melanoma: a comparison of the clinical and immunohistochemical results.

Schaling, D F, Van Der Pol, J P, Jager, M J, Van Kroonenburgh, M J, Oosterhuis, J A, Ruiter, D J

Radioimmunoscintigraphy with monoclonal antibodies (MoAbs) to melanoma associated antigens is a new technique that can be used as an additional test to detect ocular melanomas in clinically difficult...

The efficacy and safety of topical polymyxin B, neomycin and gramicidin for treatment of presumed bacterial corneal ulceration

Bosscha, M I, Van Dissel, J T, Kuijper, E J, Swart, W, Jager, M J

Aim: To evaluate the clinical efficacy and safety of topical polymyxin B, neomycin, and gramicidin for the treatment of suspected bacterial corneal ulceration at the Leiden University Medical Center.

Mechanisms of local immunosuppression in cutaneous melanoma

Polak, M E, Borthwick, N J, Gabriel, F G, Johnson, P, Higgins, B, Hurren, J, ...

Cutaneous melanoma is highly immunogenic, yet primary melanomas and metastases develop successfully in otherwise immunocompetent patients. To investigate the local immunosuppressive microenvironment,...

Activation of the MAPK pathway is a common event in uveal melanomas although it rarely occurs through mutation of BRAF or RAS

Zuidervaart, W, Van Nieuwpoort, F, Stark, M, Dijkman, R, Packer, L, Borgstein, A-M, ...

In contrast to cutaneous melanoma, there is no evidence that BRAF mutations are involved in the activation of the mitogen-activated protein kinase (MAPK) pathway in uveal melanoma, although there is...