M. Keller

Details der Publikationsliste

Zeitraum

1966 - 2009

Anzahl

129

Co-Autoren

Reinraum- und Reinheitstauglichkeit von Materialien, Komponenten und Maschinen: Vortrag gehalten auf der Lounges 2009, 17. - 19. März 2009, Karlsruhe (2009)

Keller, M.

Methoden für die Untersuchung der Reinraumtauglichkeit müssen exakt standardisiert sein, damit eine Vergleichbarkeit gewährleistet ist. Das Equipment Design spielt schon in der frühen...

A novel simulation and verification approach in an ASIC design process (2008)

D. Husmann, M. Keller, K. Mahboubi, U. Pfeiffer, C. Schumacher

For the Pre-Processor System of the ATLAS Level-1 Calorimeter Trigger we have built a fast signal-processing and readout ASIC (PPrAsic). The novel ASIC design environment incorporates algorithm...

A Novel Simulation and Veri cation Approach in an ASIC Design Process (2008)

D. Husmann, M. Keller, K. Mahboubi, U. Pfei Er, C. Schumacher

Abstract|Wehave built a fast signal-processing and readout ASIC (PPrAsic) for the Pre-Processor system of the AT-LAS Level-1 Calorimeter Trigger. Our novel ASIC design environment incorporates...

The ATLAS Level-1 (2008)

P. Hanke, D. Husmann, M. Keller, E. E. Kluge, J. Krause, ...

At the input to the calorimeter part of the Level-1 Trigger a Pre-Processor system performs the preprocessing of about 7200 analogue trigger-tower signals. The preprocessing includes digitisation,...

Equipment design for clean room use (2008)

Gommel, U., Bürger, F., Kreck, G., Keller, M.

Most of the contamination found in clean manufacturing environments originates from production equipment. As a result, it is becoming more and more important that manufacturing equipment is specially...

Ein Unscented Kalman Filter zur Schätzung von Schaltungsnichtidealitäten eines zeitkontinuierlichen Sigma-Delta Wandlers mit impliziter Dezimation (2008)

A. Buhmann, M. Keller, M. Maurer, M. Ortmanns, Y. Manoli

Nichtidealitäten einer Schaltung, wie z.B. nicht ideale Charakteristik des Operationsverstärkers und Streuungen in den Filterkoeffizienten, sind dahingehend bekannt die Effizienz von...

Rapid discovery and optimization of therapeutic antibodies against emerging infectious diseases (2008)

Rogers, J., Schoepp, R.J., Schröder, O., Clements, T.L., Holland, T.F., Li, J.Q., ...

Using a comprehensive set of discovery and optimization tools, antibodies were produced with the ability to neutralize SARS coronavirus (SARS-CoV) infection in Vero E6 cells and in animal models....

Diffusion filtering for illumination invariant face recognition: Illumination approximation with diffusion filters within retinex context (2008)

Dunker, P., Keller, M.

Face recognition becomes a very important technology in recent years for a lot of various applications. One major problem of the most state-of-the-art algorithms are different lightning conditions...

Illumination normalization for face recognition: A comparative study of conventional vs. perception-inspired algorithms (2008)

Dunker, P., Keller, M.

Face recognition has been actively investigated by the scientific community and has already taken its place in modern consumer software. However, there are still major challenges remaining e.g....

Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen (2008)

Alimohammadi, M., Bjorklund, P., Hallgren, A., Pontynen, N., Szinnai, G., Shikama, N., ...

The New England Journal of Medicine is owned, published, and copyrighted © 2008 Massachusetts Medical Society. All rights reserved

Autoimmune polyendocrine syndrome type 1 and NALP5, a parathyroid autoantigen (2008)

Alimohammadi, M., Bjorklund, P., Hallgren, A., Pontynen, N., Szinnai, G., Shikama, N., ...

The New England Journal of Medicine is owned, published, and copyrighted © 2008 Massachusetts Medical Society. All rights reserved

CERN/DRDC 93--32 RD-27 Status Report 11 August 1993 FIRST-LEVEL TRIGGER SYSTEMS FOR LHC EXPERIMENTS (2007)

Brawn Carney Ermoline, I. Brawn, R. E. Carney, Y. Ermoline, J. Garvey, D. Grant, ...

this report we describe the work that we have done so far, and propose a continued programme of work for the coming year

CERN/DRDC 94--52 RD27 Status Report 9 January 1994 FIRST-LEVEL TRIGGER SYSTEMS FOR LHC EXPERIMENTS (2007)

Brawn Carney Ermoline, I. Brawn, R. E. Carney, Y. Ermoline, J. Garvey, D. Grant, ...

this document we report on the work that has been performed and propose a programme of R&D for the next 12 months. We discuss in turn the calorimeter, muon and central trigger processors, and...

Comparison of multiple ecogenomics methods for determining ecosystem function in uranium-contaminated environments (2007)

Hazen, T.C., Dehal, P., Arkin, A.P., Fields, M.W., Keller, M., Zhou, J., ...

Background: Bioremediation may offer the only feasible strategy for the nearly intractable problem of metal and radionuclide contamination of soil and groundwater. To understand bioremediation in...

Das Linet Nutzenmodell: Auf Heller und Pfennig gerechnet (2007)

Keller, M., Stommel, H.

Die Grundlage der Entwicklung eines Modells zur Nutzenevaluierung stellt die Fokussierung des Betrachtungsraumes dar. Hierzu ist es zu Beginn notwendig, sich mit der Bandbreite möglicher...

Timber production in selectively logged tropical forests in South America (2007)

Keller, M., Asner, G.P., Blate, G., McGlocklin, J., Merry, F., Peña-Claros, M., ...

Selective logging is an extensive land-use practice in South America. Governments in the region have enacted policies to promote the establishment and maintenance of economically productive and...

A cross-cultural validation of stage development: A Rasch re-analysis of longitudinal socio-moral reasoning data (2007)

Boom, J., Wouters, H., Keller, M.

Kohlberg’s characterization of moral development as displaying an invariant hierarchical order of structurally consistent stages is losing ground. However, by applying Rasch analysis, Dawson...

Modulare mikrofluidische Funktionsplattform (2007)

Schweizer, M., Keller, M.

DE 102007054043 A1 UPAB: 20090604 NOVELTY - A medical fluid analysis unit is assembled from a series of micro-modules, each module having a standard specific analytical function. Each module has a...

Bewertung und Verteilung von Kosten und Nutzen in Wertschöpfungsnetzwerken (2006)

Kuhn, A., Hellingrath, B., Keller, M., Riha, I.V.

In den letzten Jahren haben sich die Unternehmen auf ihre Kernkompetenzen konzentriert. Dies hat dazu geführt, dass die Wertschöpfung bei den Original Equiment Manufacturers (OEM) abgenommen hat....

High pigment tomato mutants - more than just lycopene (a review) (2006)

Levin, I., Tadmor, Y., Bovy, A.G., Lieberman, M., Oren-Shamir, M., ...

Fruit constitutes a major component of our diet, providing fiber, vitamins, minerals, and many phytonutrients that promote good health. Fleshy fruits such as tomatoes already contain high levels of...

Neel Temperature of Quasi-Low-Dimensional Heisenberg Antiferromagnets (2005)

Yasuda, C., Todo, S., Hukushima, K., Alet, F., Keller, M., Troyer, M., ...

The N\\\'eel temperature, $T_{\\rm N}$, of quasi-one- and quasi-two-dimensional antiferromagnetic Heisenberg models on a cubic lattice is calculated by Monte Carlo simulations as a function of...

CD25-expressing CD8+ T cells are potent memory cells in old age (2005)

Herndler-Brandstetter, D., Schwaiger, S., Veel, E., Fehrer, C., Cioca, D.P., Almanzar, G., ...

We have recently described an IL-2/IL-4-producing CD8+CD25+ nonregulatory memory T cell population that occurs in a subgroup of healthy elderly persons who characteristically still have a good...

Schmiermittelarme Leichtbauzahnradgetriebe durch Beschichtungen (2005)

Petrik, M., Brand, J., Keller, M., Slatter, R., Koenen, H., Crummenauer, J., ...

One of the central problems in manufacturing gears is to lengthen the life and increase the load capacity of transmissions and drive elements made from lightweight materials. Using lighter materials...

Schmiermittelarme Leichtbauzahnradgetriebe durch Beschichtungen (2005)

Petrik, M., Brand, J., Keller, M., Slatter, R., Koenen, H., Crummenauer, J., ...

Eines der zentralen Probleme der Getriebehersteller ist es, die Lebensdauer und die Belastung der Getriebe - auch mit leichteren Materialien - zu erhöhen. Im Rahmen dieses Projektes wurden Methoden...

Leicht und leistungsfähig: Schmiermittelarme Leichtbauzahnradgetriebe durch Beschichtungen (2005)

Petrik, M., Brand, J., Keller, M., Slatter, R., Koenen, H., Crummenauer, J., ...

Durch die Entwicklung leichter schmiermittelfreier Zahnradgetriebe kleiner und mittlerer Leistung unter Verwendung von Leichtmetallen und Beschichtungen sollen Abmessung, Gewicht und Kosten reduziert...

Nitrous oxide fluxes and nitrogen cycling along a pasture chronosequence in Central Amazonia, Brazil (2005)

Wick, B., Veldkamp, E., De Mello, W. Z., Keller, M., Crill, P.

We studied nitrous oxide (N2O) fluxes and soil nitrogen (N) cycling following forest conversion to pasture in the central Amazon near Santarém, Pará, Brazil. Two undisturbed forest sites and 27...

Nitrous oxide fluxes and nitrogen cycling along a pasture chronosequence in Central Amazonia, Brazil (2005)

Wick, B., Veldkamp, E., De Mello, W. Z., Keller, M., Crill, P.

We studied nitrous oxide (N2O) fluxes and soil nitrogen (N) cycling following forest conversion to pasture in the central Amazon near Santarém, Pará, Brazil. Two undisturbed forest sites and 27...

Nitrous oxide fluxes and nitrogen cycling along a pasture chronosequence in Central Amazonia, Brazil (2005)

Wick, B., Veldkamp, E., De Mello, W. Z., Keller, M., Crill, P.

We studied nitrous oxide (N2O) fluxes and soil nitrogen (N) cycling following forest conversion to pasture in the central Amazon near Santarém, Pará, Brazil. Two undisturbed forest sites and 27...

Nitrous oxide fluxes and nitrogen cycling along a pasture chronosequence in Central Amazonia, Brazil (2005)

Wick, B., Veldkamp, E., De Mello, W. Z., Keller, M., Crill, P.

We studied nitrous oxide (N2O) fluxes and soil nitrogen (N) cycling following forest conversion to pasture in the central Amazon near Santarém, Pará, Brazil. Two undisturbed forest sites and 27...

Nitrous oxide fluxes and nitrogen cycling along a pasture chronosequence in Central Amazonia, Brazil (2005)

B. Wick, E. Veldkamp, M. Keller, P. Crill

We studied nitrous oxide (N<sub>2</sub>O) fluxes and soil nitrogen (N) cycling following forest conversion to pasture in the central Amazon near Santarém, Pará, Brazil. Two...

Recognition of distress and psychiatric morbidity in cancer patients: a multi-method approach (2004)

Keller, M., Sommerfeldt, S., Fischer, C., Knight, L., Riesbeck, M., Löwe, B., ...

Background: This study aimed to determine the prevalence of psychiatric morbidity and distress among 189 consecutively recruited cancer patients upon admission to surgical oncology wards, and to...

Neel Temperature of Quasi-Low-Dimensional Heisenberg Antiferromagnets (2003)

Yasuda, C., Todo, S., Hukushima, K., Alet, F., Keller, M., Troyer, M., ...

The N\'eel temperature, $T_{\rm N}$, of quasi-one- and quasi-two-dimensional antiferromagnetic Heisenberg models on a cubic lattice is calculated by Monte Carlo simulations as a function of...

Synthesis and characterization of constrained cyclosporin A derivatives containing a pseudo-proline group (2003)

Patiny, L, Guichou, JF, Keller, M, Turpin, O, Ruckle, T, Lhote, P, ...

The chemical synthesis, conformational analysis and receptor binding studies of novel constrained cyclosporin A (CsA) analogues are described. The selective insertion of pseudo-proline (PsiPro)...

Biodiversity meet the atmosphere: a global view of forest canopies (2003)

Ozanne, C. M. P., Anhuf, D., Boulter, Sarah, Keller, M., Kitching, Roger, Korner, C., ...

The forest canopy is the functional interface between 90% of Earth's terrestrial biomass and the atmosphere. The authors offer a global view of forest canopies.

Biodiversity meet the atmosphere: a global view of forest canopies (2003)

Ozanne, C. M. P., Anhuf, D., Boulter, Sarah, Keller, M., Kitching, Roger, Korner, C., ...

The forest canopy is the functional interface between 90% of Earth's terrestrial biomass and the atmosphere. The authors offer a global view of forest canopies.

Biodiversity meet the atmosphere: a global view of forest canopies (2003)

Ozanne, C. M. P., Anhuf, D., Boulter, Sarah, Keller, M., Kitching, Roger, Korner, C., ...

The forest canopy is the functional interface between 90% of Earth's terrestrial biomass and the atmosphere. The authors offer a global view of forest canopies.

Developing a Web-based User Interface for Semantic Information Retrieval (2003)

M. Keller, Daniel C. Berrios, Daniel C. Berrios, Daniel C. Berrios, Richard M. Keller, Richard M. Keller

Abstract. While there are now a number of languages and frameworks that enable computer-based systems to search stored data semantically, the optimal design for effective user interfaces for such...

Biodiversity meet the atmosphere: a global view of forest canopies (2003)

Ozanne, C. M. P., Anhuf, D., Boulter, Sarah, Keller, M., Kitching, Roger, Korner, C., ...

The forest canopy is the functional interface between 90% of Earth's terrestrial biomass and the atmosphere. The authors offer a global view of forest canopies.

Materials and methods A. Site Description (2003)

S. R. Saleska, S. D. Miller, D. M. Matross, M. L. Goulden, S. C. Wofsy, ...

We made biometric observations and eddy covariance measurements at two sites in the

Mechanisms of Na +-Ca 2+ Exchange Inhibition by Amphiphiles in Cardiac Myocytes: Importance of Transbilayer Movement (2003)

M. Keller, C. Pignier, E. Niggli, M. Egger

Abstract. The membrane lipid environment and lipid signaling pathways are potentially involved in the modulation of the activity of the cardiac Na +-Ca 2+ exchanger (NCX). In the present study...

Defective associations between blood vessels and brain parenchyma lead to cerebral hemorrhage in mice lacking alpha v integrins (2002)

McCarty, J. H., Monahan-Earley, R. A., Brown, L. F., Keller, M., Gerhardt, H., Rubin, K., ...

Mouse embryos genetically null for the alphav integrin subunit develop intracerebral hemorrhages at midgestation and die shortly after birth. A key question is whether the hemorrhage arises from...

Diversity of Sinorhizobium meliloti from the Central Asian Alfalfa Gene Center (2002)

Roumiantseva, M.L., Andronov, E.E., Sharypova, L.A., Dammann-Kalinowski, T., Keller, M., Young, J.P.W., ...

Sinorhizobium meliloti was isolated from nodules and soil from western Tajikistan, a center of diversity of the host plants (Medicago, Melilotus, and Trigonella species). There was evidence of...

Dynamical mean-field theory for the normal phase of the attractive Hubbard model (2001)

Keller, M., Metzner, W., Schollwoeck, U.

We analyze the normal phase of the attractive Hubbard model within dynamical mean-field-theory. We present results for the pair-density, the spin-susceptibility, the specific heat, the momentum...

Dynamical mean-field theory for pairing and spin gap in the attractive Hubbard model (2001)

Keller, M., Metzner, W., Schollwoeck, U.

We solve the attractive Hubbard model for arbitrary interaction strengths within dynamical mean-field theory. We compute the transition temperature for superconductivity and analyze electron pairing...

Pseudoproline-containing analogues of morphiceptin and endomorphin-2: Evidence for a cis Tyr-Pro amide bond in the bioactive conformation (2001)

Keller, M, Boissard, C, Patiny, L, Chung, NN, Lemieux, C, Mutter, M, ...

Analogues of the opioid peptides [D-Phe(3)]morphiceptin (H-Tyr-Pro-D-Phe-Pro-NH2) and endomorphin-2 (H-Tyr-Pro-Phe-Phe-NH2) containing the pseudoproline (Psi Pro) (4R)-thiazolidine-4-carboxylic acid...

Pseudoprolines (Psi Pro) in drug design: Direct insertion of Psi Pro systems into cyclosporin C (2000)

Keller, M, Wohr, T, Dumy, P, Patiny, L, Mutter, M

The insertion of acetals that exhibit variable structural features into complex peptides such as cyclosporin C (CsC) results in oxazolidine derivatives (pseudoprolines, Psi Pro) of tailored...

Bohrgestaengemagazin (1999)

Bayer, H., Doerfler, G., Steck, A., Keller, M., Cottone, N., Braeuning, U.

NOVELTY - The drilling rod magazine (10) has a multiple of tool places (12) for the reception of the tools (8). The tool places are respectively formed by a follower (14), movable along a conveying...

Pseudo-prolines in cyclic peptides: Conformational stabilisation of cyclo[Pro-Thr(Psi(Me,Me)Pro)-Pro] (1999)

Ruckle, T, De Lavallaz, P, Keller, M, Dumy, P, Mutter, M

Linear peptide H-Pro-Thr(Psi(Me,Me)pro)-Pro-OH containing a preformed cis-Pro-Thr(Psi(Me,Me)pro) tertiary amide bond cyclises instantaneously and free of formation of oligomeric structures to the...

Pseudo-prolines: Induction of cis/trans-conformational interconversion by decreased transition state barriers (1999)

Mutter, M, Wohr, T, Gioria, S, Keller, M

Molecular events such as cis/trans isomerization of Xaa-Pro tertiary amide bonds in peptides and proteins are slow on the overall time scale of the formation of a final biostructure and are,...

Stereocontrol during the formation of 2-C mono-arylated pseudo-prolines by aromatic stacking interaction (1999)

Keller, M, Lehmann, C, Mutter, M

When treated with anisaldehyde dimethylacetal the O-benzyl ester protected dipeptide Fmoc-NMeIle-Thr-OBzl (2, cf. Scheme 3), cyclizes to the 2-C(S) epimer 3b assigned by NMR spectroscopy to chirality...

Configurational and conformational control on formation and oligomerization of 2-C mono-arylated pseudo-proline dipeptide building units by aromatic stacking interactions (1999)

Keller, M., Mutter, M., Lehmann, C.

Electrophilically induced cyclic acetal formation of the O-benzyl dipeptide esters Fmoc-NMeIle-Thr-OBn (1) and of Fmoc-Pro-Thr-OBn (6) has been observed to lead predominantly to the (R) diastereomers...

Enhancing the proline effect: Pseudo-prolines for tailoring cis/trans isomerization (1998)

Keller, M, Sager, C, Dumy, P, Schutkowski, M, Fischer, GS, Mutter, M

Cis-trans isomerization of proline-like oxazolidines and thiazolidines, denoted pseudo-prolines, is investigated spectrophotometrically with a chymotrypsin coupled assay and by H-1 NMR. A series of...

Pseudo-prolines as a molecular hinge: Reversible induction of cis amide bonds into peptide backbones (1997)

Dumy, P, Keller, M, Ryan, DE, Rohwedder, B, Wohr, T, Mutter, M

Serine, threonine-derived (4S)-oxazolidine-4-carboxylic acid, and cysteine-derived (4R)-thiazolidinecarboxylic acid, denoted pseudo-proline (Xaa[Psi(R1,R2)pro]), serve as structure disrupting,...

Anatomy of the Precordillera (Argentina) during cambro-ordovician times : implications for the Laurentia-Gondwana transfer of the Cuyania terrane (1996)

Keller, M.

Dans la Précordillère d'Argentine occidentale, la séquence carbonatée d'âge cambrien inférieur à ordovicien inférieur est typique d'une marge passive, alors que les sédiments...

First-Level Trigger Systems For Lhc Experiments (1994)

I. Brawn, R.E. Carney, Y. Ermoline, J. Garvey, D. Grant, R. Harris, ...

this document we report on the work that has been performed and propose a programme of R&D for the next 12 months. We discuss in turn the calorimeter, muon and central trigger processors, and...

Evidence of an upper ordovician thermo-metamorphic event in the SW-Corner of the Cantabrian Mountains (N-Spain) (1992)

Keller, M., Krumm, S.

According to Illite «crystallinity» (IC) data, the metamorphic evolution of the SW Cantabrian Mountains took place in several steps. After a Precambrian deformation with...

In Euglena, spliced-leader RNA (SL-RNA) and 5S rRNA genes are tandemly repeated (1992)

Keller, M., Tessier, L. H., Chan, R. L., Weil, J. H., Lmbault, P.

In Euglena gracilis, a 26 nucleotide leader sequence (spliced leader sequence = SL) Is transferred by trans-splicing to the 5' end of a vast majority of cytoplasmic mRNAs (8). The SL originates from...

An Energy-Independent Dose Rate Meter for Beta and Gamma Radiation (1986)

Heinzelmann, M., Keller, M.

An easy to handle dose rate meter has been developed at the J�lich Nuclear Research Centre with a small probe for the energy-independent determination of the dose rate in mixed radiation fields....

Dosemeter for Determining Skin Dose (1982)

Heinzelmann, M., Schüren, H., Keller, M.

The dosemeter described here consists of three standard commercial LiF thermoluminescent detectors mounted one behind the other. This dosemeter enables the skin dose to be determined independent of...

Reactions depending on iron sulfide and linking geochemistry with biochemistry.

Blöchl, E, Keller, M, Wachtershäuser, G, Stetter, K O

Iron sulfide gives rise to unusual reducing reactions: some dependent on FeS/H2S synergism [NO-3 --> NH3; HC(three bonds)CH--> H2C=CH2, H3C-CH3; -CH2-CO- --> -CH=CH-, -CH2-CH2-; HS-CH2-COOH -->...

A homeodomain protein binds to gamma-globin gene regulatory sequences.

Lavelle, D, Ducksworth, J, Eves, E, Gomes, G, Keller, M, Heller, P, ...

Developmental regulation of gamma-globin gene expression probably occurs through developmental-stage-specific trans-acting factors able to promote the interaction of enhancer elements located in the...

Characterization of multiple alternative RNAs resulting from antisense transcription of the PR264/SC35 splicing factor gene.

Sureau, A, Soret, J, Guyon, C, Gaillard, C, Dumon, S, Keller, M, ...

The PR264/SC35 splicing factor belongs to the family of SR proteins which function as essential and alternative splicing factors. Here, we report that the human PR264/SC35 locus is bidirectionally...

Synergistic activity of a Bacillus thuringiensis delta-endotoxin and a bacterial endochitinase against Spodoptera littoralis larvae.

Regev, A, Keller, M, Strizhov, N, Sneh, B, Prudovsky, E, Chet, I, ...

In an attempt to increase the insecticidal effect of the delta-endotoxin crystal protein CryIC on the relatively Cry-insensitive larvae of Spodoptera littoralis, a combination of CryIC and...

The 32-kilobase exp gene cluster of Rhizobium meliloti directing the biosynthesis of galactoglucan: genetic organization and properties of the encoded gene products.

Becker, A, Rüberg, S, Küster, H, Roxlau, A A, Keller, M, Ivashina, T, ...

Proteins directing the biosynthesis of galactoglucan (exopolysaccharide II) in Rhizobium meliloti Rm2011 are encoded by the exp genes. Sequence analysis of a 32-kb DNA fragment of megaplasmid 2...

Correlation between antibiotic resistance, phage-like particle presence, and virulence in Rhodococcus equi human isolates.

Nordmann, P, Keller, M, Espinasse, F, Ronco, E

Rhodococcus equi is a gram-positive coccobacillus that appears to be emerging as a pulmonary pathogen in AIDS patients. In four human clinical isolates, two antibiotic resistance phenotypes were...

In Euglena, spliced-leader RNA (SL-RNA) and 5S rRNA genes are tandemly repeated.

Keller, M, Tessier, L H, Chan, R L, Weil, J H, Imbault, P

In Euglena gracilis, a 26 nucleotide leader sequence (spliced leader sequence = SL) is transferred by trans-splicing to the 5' end of a vast majority of cytoplasmic mRNAs (8). The SL originates from...

Short leader sequences may be transferred from small RNAs to pre-mature mRNAs by trans-splicing in Euglena.

Tessier, L H, Keller, M, Chan, R L, Fournier, R, Weil, J H, Imbault, P

Very closely related short sequences are present at the 5' end of cytoplasmic mRNAs in Euglena as evidenced by comparison of cDNA sequences and hybrid-arrested translation experiments. By cloning...

Eight small subunits of Euglena ribulose 1-5 bisphosphate carboxylase/oxygenase are translated from a large mRNA as a polyprotein.

Chan, R L, Keller, M, Canaday, J, Weil, J H, Imbault, P

The small subunit (SSU) of ribulose 1-5 bisphosphate carboxylase/oxygenase is a 15 kd protein in Euglena gracilis. The protein is synthesized as a 130 kd precursor as shown by immunoprecipitation of...

Aphid transmission of cauliflower mosaic virus requires the viral PIII protein.

Leh, V, Jacquot, E, Geldreich, A, Hermann, T, Leclerc, D, Cerutti, M, ...

The open reading frame (ORF) III product (PIII) of cauliflower mosaic virus is necessary for the infection cycle but its role is poorly understood. We have used in vitro protein binding ('far...

OA1 mutations and deletions in X-linked ocular albinism.

Schnur, R E, Gao, M, Wick, P A, Keller, M, Benke, P J, Edwards, M J, ...

X-linked ocular albinism (OA1), Nettleship-Falls type, is characterized by decreased ocular pigmentation, foveal hypoplasia, nystagmus, photodysphoria, and reduced visual acuity. Affected males...

Sequence Analysis of the 144-Kilobase Accessory Plasmid pSmeSM11a, Isolated from a Dominant Sinorhizobium meliloti Strain Identified during a Long-Term Field Release Experiment†

Stiens, M., Schneiker, S., Keller, M., Kuhn, S., Pühler, A., Schlüter, A.

The genome of Sinorhizobium meliloti type strain Rm1021 consists of three replicons: the chromosome and two megaplasmids, pSymA and pSymB. Additionally, many indigenous S. meliloti strains possess...

Evaluation of specific value of endoscopic biopsies and brush cytology for malignancies of the oesophagus and stomach.

Witzel, L, Halter, F, Grétillat, P A, Scheurer, U, Keller, M

The value of multiple biopsies and brush cytology at oesophago-gastroscopy was assessed in relation to macroscopy and localization on 100 verified tumours in a prospective study. The cumulative...

Treatment of hypertrophic obstructive cardiomyopathy with verapamil.

Kaltenbach, M, Hopf, R, Kober, G, Bussmann, W D, Keller, M, Petersen, Y

Twenty-two patients with hypertrophic obstructive cardiomyopathy were treated with the calcium inhibitor, verapamil, which was administered in a mean oral dose of 480 mg per day. After an average of...

Reversible neuropsychological deficits after mild traumatic brain injury

Keller, M, Hiltbrunner, B, Dill, C, Kesselring, J

OBJECTIVES—To determine the influence of motivation on performance in a divided attention test of patients after mild traumatic brain injury (MBI).
METHODS—Comparison of the performance of 12...

Rapid discovery and optimization of therapeutic antibodies against emerging infectious diseases

Rogers, J., Schoepp, R.J., Schröder, O., Clements, T.L., Holland, T.F., Li, J.Q., ...

Using a comprehensive set of discovery and optimization tools, antibodies were produced with the ability to neutralize SARS coronavirus (SARS-CoV) infection in Vero E6 cells and in animal models....

Psychological distress in cancer patients assessed with an expert rating scale

Herschbach, P, Book, K, Brandl, T, Keller, M, Lindena, G, Neuwöhner, K, ...

The purpose of this study was to investigate psychosocial stress in a large sample of cancer patients using an expert rating scale. Specific aims were to analyse the relevance of setting variables...