M. Kondo

Details der Publikationsliste

Zeitraum

1978 - 2010

Anzahl

164

Co-Autoren

Design integration of the LHD-Type energy reactor FFHR2. (2009)

Sagara, A., Imagawa, S., Kozaki, Y., Mitarai, O., Tanaka, T., Watanabe, T., ...

Development of Physics and Technology of Stellarators/Heliotrons en route to DEMO : Proc.of the 18th Internat.Toki, Conf., Toki City, J, December 9-12, 2008

Nature of doped a-Si:H / c-Si interface recombination (2009)

De Wolf, S, Kondo, M

Doped hydrogenated amorphous silicon a-Si:H films of only a few nanometer thin find application in a-Si:H/crystalline silicon heterojunction solar cells. Although such films may yield a field effect...

On the Transfer Principle in Fuzzy Theory (2008)

M. Kondo, W. A. Dudek

We show in this paper that almost all results proved in many papers about fuzzy algebras can be proved uniformly and immediately by using so-called “Transfer Principle”. 1

Understanding of passivation mechanism in heterojunction c-Si solar cells (2008)

Kondo, M, De-Wolf, S, Fujiwara, H

Intrinsic hydrogenated amorphous silicon (a-Si:H) films can yield in outstanding electronic surface passivation of crystalline silicon (c-Si) wafers as utilized in the HIT (heterojunction with...

Identification of a novel autoantibody reactive with 155 and 140 kDa nuclear proteins in patients with dermatomyositis: an association with malignancy (2007)

Kaji, K., Fujimoto, M., Hasegawa, M., Kondo, M., Saito, Y., Komura, K., ...

Objective. Myositis-specific autoantibodies (MSAs) are a useful tool in diagnosis, defining clinical subsets and predicting prognosis of dermatomyositis (DM) and polymyositis (PM). In this study, we...

Negative electroretinograms in pericentral pigmentary retinal degeneration (2006)

Hotta, K ; JFA; CORA, Kondo, M, Nakamura, M, Hotta, Junichi; U0049263 ;, Terasaki, H, Miyake, Y, ...

The clinical presentation and electrophysiological findings are described of three consecutive cases with pericentral pigmentary retinal degeneration. The responses to bright flashes after dark...

Identification of a novel autoantibody reactive with 155 and 140 kDa nuclear proteins in patients with dermatomyositis: an association with malignancy (2006)

Kaji, K., Fujimoto, M., Hasegawa, M., Kondo, M., Saito, Y., Komura, K., ...

Objective. Myositis-specific autoantibodies (MSAs) are a useful tool in diagnosis, defining clinical subsets and predicting prognosis of dermatomyositis (DM) and polymyositis (PM). In this study, we...

Floral Scent Diversity is Differently Expressed in Emitted and Endogenous Components in Petunia axillaris Lines (2006)

KONDO, M., OYAMA-OKUBO, N., ANDO, T., MARCHESI, E., NAKAYAMA, M.

• Background and Aims Among the subspecies of Petunia axillaris are various lines emitting sensorially different scents. Analysis of variations in floral scent among genetically close individuals...

Floral Scent Diversity is Differently Expressed in Emitted and Endogenous Components in Petunia axillaris Lines (2006)

KONDO, M., OYAMA-OKUBO, N., ANDO, T., MARCHESI, E., NAKAYAMA, M.

• Background and Aims Among the subspecies of Petunia axillaris are various lines emitting sensorially different scents. Analysis of variations in floral scent among genetically close individuals...

Identification of a novel autoantibody reactive with 155 and 140 kDa nuclear proteins in patients with dermatomyositis: an association with malignancy (2006)

Kaji, K., Fujimoto, M., Hasegawa, M., Kondo, M., Saito, Y., Komura, K., ...

Objective. Myositis-specific autoantibodies (MSAs) are a useful tool in diagnosis, defining clinical subsets and predicting prognosis of dermatomyositis (DM) and polymyositis (PM). In this study, we...

Floral Scent Diversity is Differently Expressed in Emitted and Endogenous Components in Petunia axillaris Lines (2006)

KONDO, M., OYAMA-OKUBO, N., ANDO, T., MARCHESI, E., NAKAYAMA, M.

• Background and Aims Among the subspecies of Petunia axillaris are various lines emitting sensorially different scents. Analysis of variations in floral scent among genetically close individuals...

Serum laminin, type IV collagen and hyaluronan as fibrosis markers in non-alcoholic fatty liver disease (2005)

Santos,V.N. Dos, Leite-Mór,M.M.B., Kondo,M., Martins,J.R., Nader,H., Lanzoni,V.P., ...

Hepatic fibrosis in patients with non-alcoholic fatty liver disease is associated with progression of the disease. In the present study, we analyzed the discriminative ability of serum laminin, type...

On the transfer principle in fuzzy theory (2005)

Kondo, M., Dudek, W. A.

We show in this paper that almost all results proved in many papers about fuzzy algebras can be proved uniformly and immediately by using so-called Transfer Principle.

Disruption of the BLM gene in ATM-null DT40 cells does not exacerbate either phenotype (2004)

Fukao, T, Chen, P, Ren, J, Kaneko, H, Zhang, GX, Kondo, M, ...

Bloom syndrome and ataxia-telangiectasia are autosomal recessive human disorders characterized by immunodeficiency, genome instability and predisposition to develop cancer. Recent data reveal that...

Disruption of the BLM gene in ATM-null DT40 cells does not exacerbate either phenotype (2004)

Fukao, T, Chen, P, Ren, J, Kaneko, H, Zhang, GX, Kondo, M, ...

Bloom syndrome and ataxia-telangiectasia are autosomal recessive human disorders characterized by immunodeficiency, genome instability and predisposition to develop cancer. Recent data reveal that...

Genomic Organization and Expression of the Doublesex-Related Gene Cluster in Vertebrates and Detection of Putative Regulatory Regions for DMRT1 (2001)

Brunner, B., Hornung, U., Shan, Z., Nanda, I., Kondo, M., Tsend-Ayush, Enkhjargal, ...

Genes related to the Drosophila melanogaster doublesex and Caenorhabditis elegans mab-3 genes are conserved in human. They are identified by a DNA-binding homology motif, the DM domain, and...

Genomic Organization and Expression of the Doublesex-Related Gene Cluster in Vertebrates and Detection of Putative Regulatory Regions for DMRT1 (2001)

Brunner, B., Hornung, U., Shan, Z., Nanda, I., Kondo, M., Tsend-Ayush, Enkhjargal, ...

Genes related to the Drosophila melanogaster doublesex and Caenorhabditis elegans mab-3 genes are conserved in human. They are identified by a DNA-binding homology motif, the DM domain, and...

Genomic Organization and Expression of the Doublesex-Related Gene Cluster in Vertebrates and Detection of Putative Regulatory Regions for DMRT1 (2001)

Brunner, B., Hornung, U., Shan, Z., Nanda, I., Kondo, M., Tsend-Ayush, Enkhjargal, ...

Genes related to the Drosophila melanogaster doublesex and Caenorhabditis elegans mab-3 genes are conserved in human. They are identified by a DNA-binding homology motif, the DM domain, and...

Analysis of p53 tumour suppressor gene somatic mutations in rheumatoid arthritis synovium (2000)

Inazuka, M., Tahira, T., Horiuchi, T., Harashima, S., Sawabe, T., Kondo, M., ...

Objective. In order to study the role of the p53 tumour suppressor gene in the proliferation of rheumatoid arthritis (RA) synovium, we analysed the mutation of p53 in the synovial...

Development of High-Strength, Low-Alloy Titanium. (1998)

Shindo, T., Watanabe, T., Kondo, M.

Nippon Steel has developed a new high-strength titanium material designated TIX-80 consisting of low-alloy Ti-O-N-Fe system; the material shows outstanding strength-ductility balance: tensile...

Development of High-Strength Low-Alloy Titanium (TIX-80). (1998)

Shindo, T., Kondo, M., Watanabe, T.

A low-alloy Ti-O-N-Fe composition was the basis for the development of a general purpose high-strength titanium (tix-80) with a good strength-ductility balance (tensile strength of 80 kgf/sq. mm and...

High-Speed Wavelength Switching Experiment for Wavelength-Division and Time-Division Hybrid Switching Networks Using LiNbO3 Fabry-Perot Tunable Wavelength Filters, (1992)

Nishio, M., Urino, Y., Kouta, H., Kondo, M., Suzuki, S.

Fast wavelength switching of less than 0.4 ns has been realized when using a LiNbO3 tunable filter. This permits wavelength-division and time-division hybrid switching networks to adopt a 2-Gbps...

CONSTRUCTION OF POLARIZED HEAVY ION SOURCE AT RCNP (1990)

Tanaka, M., Ohshima, T., Abe, K., Katori, K., Fujiwara, M., Itahashi, T., ...

A recent progress in the construction of a polarized heavy ion source at RCNP, Osaka University is presented. A basic principle of the polarization is a spin and charge exchange collision between a...

CONSTRUCTION OF POLARIZED HEAVY ION SOURCE AT RCNP (1990)

Tanaka, M., Ohshima, T., Abe, K., Katori, K., Fujiwara, M., Itahashi, T., ...

A recent progress in the construction of a polarized heavy ion source at RCNP, Osaka University is presented. A basic principle of the polarization is a spin and charge exchange collision between a...

CONSTRUCTION OF POLARIZED HEAVY ION SOURCE AT RCNP (1990)

Tanaka, M., Ohshima, T., Abe, K., Katori, K., Fujiwara, M., Itahashi, T., ...

A recent progress in the construction of a polarized heavy ion source at RCNP, Osaka University is presented. A basic principle of the polarization is a spin and charge exchange collision between a...

CONSTRUCTION OF POLARIZED HEAVY ION SOURCE AT RCNP (1990)

Tanaka, M., Ohshima, T., Abe, K., Katori, K., Fujiwara, M., Itahashi, T., ...

A recent progress in the construction of a polarized heavy ion source at RCNP, Osaka University is presented. A basic principle of the polarization is a spin and charge exchange collision between a...

CONSTRUCTION OF POLARIZED HEAVY ION SOURCE AT RCNP (1990)

Tanaka, M., Ohshima, T., Abe, K., Katori, K., Fujiwara, M., Itahashi, T., ...

A recent progress in the construction of a polarized heavy ion source at RCNP, Osaka University is presented. A basic principle of the polarization is a spin and charge exchange collision between a...

VALENCY ELECTRON CONTROL IN A GLOW DISCHARGE PRODUCED a-SiC : H AND ITS APPLICATION TO a-Si SOLAR CELL (1981)

Tawada, Y., Kondo, M., Okamoto, H., Hamakawa, Y.

A clear valency electron controlability has been found in hydrogenated amorphous silicon carbide produced by the plasma deposition of [SiH4 (1-x) + CH4 (x)] gas mixture. A series of experimental...

VALENCY ELECTRON CONTROL IN A GLOW DISCHARGE PRODUCED a-SiC : H AND ITS APPLICATION TO a-Si SOLAR CELL (1981)

Tawada, Y., Kondo, M., Okamoto, H., Hamakawa, Y.

A clear valency electron controlability has been found in hydrogenated amorphous silicon carbide produced by the plasma deposition of [SiH4 (1-x) + CH4 (x)] gas mixture. A series of experimental...

VALENCY ELECTRON CONTROL IN A GLOW DISCHARGE PRODUCED a-SiC : H AND ITS APPLICATION TO a-Si SOLAR CELL (1981)

Tawada, Y., Kondo, M., Okamoto, H., Hamakawa, Y.

A clear valency electron controlability has been found in hydrogenated amorphous silicon carbide produced by the plasma deposition of [SiH4 (1-x) + CH4 (x)] gas mixture. A series of experimental...

VALENCY ELECTRON CONTROL IN A GLOW DISCHARGE PRODUCED a-SiC : H AND ITS APPLICATION TO a-Si SOLAR CELL (1981)

Tawada, Y., Kondo, M., Okamoto, H., Hamakawa, Y.

A clear valency electron controlability has been found in hydrogenated amorphous silicon carbide produced by the plasma deposition of [SiH4 (1-x) + CH4 (x)] gas mixture. A series of experimental...

VALENCY ELECTRON CONTROL IN A GLOW DISCHARGE PRODUCED a-SiC : H AND ITS APPLICATION TO a-Si SOLAR CELL (1981)

Tawada, Y., Kondo, M., Okamoto, H., Hamakawa, Y.

A clear valency electron controlability has been found in hydrogenated amorphous silicon carbide produced by the plasma deposition of [SiH4 (1-x) + CH4 (x)] gas mixture. A series of experimental...

Solid-liquid phase boundaries of lens protein solutions.

Berland, C R, Thurston, G M, Kondo, M, Broide, M L, Pande, J, Ogun, O, ...

We report measurement of the solid-liquid phase boundary, or liquidus line, for aqueous solutions of three pure calf gamma-crystallin proteins: gamma II, gamma IIIa, and gamma IIIb. We also studied...

2,4-Dichlorophenoxybutyric acid-resistant mutants of Arabidopsis have defects in glyoxysomal fatty acid beta-oxidation.

Hayashi, M, Toriyama, K, Kondo, M, Nishimura, M

It has been demonstrated previously that 2,4-dichlorophenoxybutyric acid (2,4-DB) is metabolized to produce a herbicide, 2,4-D, by the action of peroxisomal fatty acid beta-oxidation in higher...

Expression of a vacuolar protein (VP24) in anthocyanin-producing cells of sweet potato in suspension culture.

Nozue, M, Yamada, K, Nakamura, T, Kubo, H, Kondo, M, Nishimura, M

VP24, an abundant protein of 24 kD, was found to accumulate in the anthocyanin-containing vacuoles of cells of sweet potato (Ipomoea batatas) in suspension culture. Light-induced expression of VP24...

Targeting and processing of a chimeric protein with the N-terminal presequence of the precursor to glyoxysomal citrate synthase.

Kato, A, Hayashi, M, Kondo, M, Nishimura, M

Glyoxysomal citrate synthase in pumpkin is synthesized as a precursor that has a cleavable presequence at its N-terminal end. To investigate the role of the presequence in the transport of the...

In vitro and in vivo antibacterial activities of carumonam (AMA-1080), a new N-sulfonated monocyclic beta-lactam antibiotic.

Imada, A, Kondo, M, Okonogi, K, Yukishige, K, Kuno, M

The in vitro and in vivo antibacterial activities of carumonam (AMA-1080), a synthetic sulfazecin derivative, were compared with those of aztreonam, cefoperazone, ceftazidime, and cefsulodin....

Novel morphological changes in gram-negative bacteria caused by combination of bulgecin and cefmenoxime.

Nakao, M, Yukishige, K, Kondo, M, Imada, A

The mode of action of bulgecin was investigated by examining its bactericidal and bacteriolytic activities, its effect on bacterial morphology, and its interaction with penicillin-binding proteins...

Cefmenoxime (SCE-1365), a novel broad-spectrum cephalosporin: in vitro and in vivo antibacterial activities.

Tsuchiya, K, Kondo, M, Kida, M, Nakao, M, Iwahi, T, Nishi, T, ...

The activity of cefmenoxime (SCE-1365), 7 beta-[2-(2-aminothiazol-4-yl)-(Z)-2-methoxyiminoacetamido]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid, was compared with that of...

In vitro and in vivo activities of SCE-2787, a new parenteral cephalosporin with a broad antibacterial spectrum.

Iwahi, T, Okonogi, K, Yamazaki, T, Shiki, S, Kondo, M, Miyake, A, ...

SCE-2787, a new cephalosporin having a condensed azolium moiety in the 3 position and an aminothiadiazolyl group in the 7 beta side chain, was evaluated for its in vitro and in vivo activities in...

Occurrence in Bacillus megaterium of uridine 5'-diphospho-N-acetylgalactosamine and uridine 5'-diphosphogalactosamine, intermediates in the biosynthesis of galactosamine-6-phosphate polymer.

Nishikawa, J, Tada, M, Takubo, Y, Nishihara, T, Kondo, M

We isolated two galactosamine derivatives from Bacillus megaterium sporulating cells by lectin affinity chromatography followed by DEAE-Sephadex A-25 chromatography. From chemical analyses and...

Effect of alanine-containing dipeptides on germination of Bacillus thiaminolyticus spores.

Watabe, K, Sano, K, Otani, M, Okada, Y, Kakiuchi, Y, Kondo, M

Stereoisomeric alanylalanine (Ala-Ala) derivatives were examined for their effects on germination of Bacillus thiaminolyticus spores. L-Ala-L-Ala and L-Ala-glycine were effective in inducing...

Differentiation of human immunodeficiency virus type 1 (HIV-1) infections with HIV-2-cross-reacting antibody from mixed infections with HIV-1 and HIV-2 by serological absorption test.

Imai, M, Hayashi, T, Kondo, M, Saito, T, Ito, A, Hayami, M, ...

The interpretation of dual seroreactivity with human immunodeficiency virus type 1 (HIV-1) and HIV-2 in blood samples is a serious problem facing AIDS researchers worldwide. Some samples of sera from...

Prior enrichment of human immunodeficiency virus DNA with probe DNA particles for efficient PCR diagnosis.

Tano, H, Fan, K, Kitajima, M A, Kasai, K, Tamatsukuri, S, Furuichi, Y, ...

We report here a novel method by which one can recover human immunodeficiency virus (HIV) DNA in a small volume (approximately 50 microliters) of solution from 8 ml of crude cell lysate which...

Effect of recombinant human interleukin-2 on the course of experimental chronic respiratory tract infection caused by Klebsiella pneumoniae in mice.

Iizawa, Y, Nishi, T, Kondo, M, Tsuchiya, K, Imada, A

The effect of recombinant human interleukin-2 (rIL-2) on the course of experimental chronic respiratory tract infection caused by Klebsiella pneumoniae in mice was examined. rIL-2 was administered...

Complete nucleotide sequence of the E. coli glutathione synthetase gsh-II.

Gushima, H, Yasuda, S, Soeda, E, Yokota, M, Kondo, M, Kimura, A

The nucleotide sequence of the cloned DNA, 1,478 bp in length coding for glutathione synthetase (GSH-II) of E. coli B has been determined. Amino acid and nucleotide sequence analyses have assigned...

Non-polyadenylated 22 s ribonucleoprotein particle is insensitive to translational inhibitor RNA of cryptobiotic gastrulae of Artemia salina.

De Herdt, E, Slegers, H, Piot, E, Kondo, M

A free cytoplasmic 22 S ribonucleoprotein particle exhibiting a major template activity in rabbit reticulocyte system has been identified in the cryptobiotic gastrulae of Artemia salina. This...

Messenger ribonucleoprotein complexes of cryptobiotic embryos of Artemia salina.

Slegers, H, Kondo, M

Poly(A)-containing ribonucleoprotein (poly(A)+-RNP) particles in the post-mitochondrial supernatant of cryptobiotic embryos of Artemia salina were characterized by hybridization to [3H]-poly(U). By...

Comparative in vitro activities of SCE-129, sulbenicillin, gentamicin, and dibekacin against Pseudomonas.

Tsuchiya, K, Kondo, M

Against sulbenicillin- and gentamicin-susceptible strains of Pseudomonas aeruginosa, SCE-129 was about 10 times more active than sulbenicillin and had a similar activity to gentamicin and dibekacin....

Diabetes due to secretion of a structurally abnormal insulin (insulin Wakayama). Clinical and functional characteristics of [LeuA3] insulin.

Nanjo, K, Sanke, T, Miyano, M, Okai, K, Sowa, R, Kondo, M, ...

We have identified a non-insulin-dependent diabetic patient with fasting hyperinsulinemia (90 microU/ml), an elevated insulin:C-peptide molar ratio (1.68; normal, 0.05-0.20), normal insulin...

Prevention of adoptively transferred diabetes in nonobese diabetic mice with IL-10-transduced islet-specific Th1 lymphocytes. A gene therapy model for autoimmune diabetes.

Moritani, M, Yoshimoto, K, Ii, S, Kondo, M, Iwahana, H, Yamaoka, T, ...

Four pancreatic islet-specific CD4+ helper T (Th) 1 (Th1) clones and two Th1 clones transduced with an SRalpha promoter-linked murine IL-10 (mIL-10) cDNA of 2.0-6.0 x 10(6) cells were adoptively...

Characterization of metallothionein cDNAs induced by cadmium in the nematode Caenorhabditis elegans.

Imagawa, M, Onozawa, T, Okumura, K, Osada, S, Nishihara, T, Kondo, M

cDNAs of metallothioneins (MTs) in the nematode Caenorhabditis elegans were characterized. The MT-II clone encodes 62 amino acid residues and the predicted Mr is 6462. The MT-I clone contains an...

Identification of the mRNA and polypeptide subunit for prostaglandin endoperoxide synthase from mouse mastocytoma P-815 cells.

Kondo, M, Koshihara, Y, Kawamura, M, Murota, S

Cloned mouse mastocytoma P-815.2-E-6 cells are barely able to synthesize prostaglandins because of a lack of prostaglandin endoperoxide synthase activity. However, the addition of sodium n-butyrate...

Biophysical characterization of Artemia salina (L.) extracellular haemoglobins.

Wood, E J, Barker, C, Moens, L, Jacob, W, Heip, J, Kondo, M

Sedimentation coefficients (s0 20,w) of 11.57 +/- 0.10 S and 11.52 +/- 0.09 S were assigned for Artemia salina (L.) extracellular haemoglobins II and III respectively. These values are not...

A cryptobiosis-specific 19S protein complex of Artemia salina gastrulae.

De Herdt, E, De Voeght, F, Clauwaert, J, Kondo, M, Slegers, H

The postribosomal supernatant of Artemia salina cryptobiotic embryos contains a large quantity of a 19S protein complex. An amount of 3.6 mg/g of cysts is measured by immunoprecipitation with...

Selective resistance to desiccation of nuclear ribonucleic acid synthesis in isolated nuclei of Artemia salina embryos during pre-emergence development.

Chaffoy, D D, Kondo, M

The developing gastrula embryos of Artemia salina are resistant to a complete redesiccation during a period of pre-emergence development. Isolated nuclei from these dehydrated embryos could retain a...

Characterization of the extracellular haemoglobins of Artemia salina.

Moens, L, Kondo, M

The following factors were measured for extracellular haemoglobins of Artemia salina: a minimal molecular weight of globin chain per haem group (based on the iron and haem contents), the absorption...

Preferential inhibition by poly(adenylic acid) of minus-strand synthesis by bacteriophage Qbeta ribonucleic acid replicase.

Kondo, M

Among the homopolymers examined, poly(A) was found to inhibit preferentially the synthesis of the minus strand by bacteriophage Qbeta RNA replicase in the presence of host factor. A specific...

Biosynthesis of Poly(3-Hydroxyalkanoic Acid) Copolymer from CO(inf2) in Pseudomonas acidophila through Introduction of the DNA Fragment Responsible for Chemolithoautotrophic Growth of Alcaligenes hydrogenophilus

Yagi, K., Miyawaki, I., Kayashita, A., Kondo, M., Kitano, Y., Murakami, Y., ...

Pseudomonas acidophila is a bacterial strain producing a poly(3-hydroxyalkanoic acid) (PHA) copolymer from low-molecular-weight organic compounds such as formate and acetate. The genes responsible...

Role of nitric oxide in tachykinin-induced increase in potential difference of rabbit tracheal mucosa.

Tamaoki, J, Sakai, A, Kondo, M, Takemura, H, Konno, K

1. The effect of tachykinins on transepithelial potential difference (PD) of rabbit trachea and possible involvement of nitric oxide (NO) generation in vivo were investigated. 2. Perfusion of...

A detailed linkage map of medaka, Oryzias latipes: comparative genomics and genome evolution.

Naruse, K, Fukamachi, S, Mitani, H, Kondo, M, Matsuoka, T, Kondo, S, ...

We mapped 633 markers (488 AFLPs, 28 RAPDs, 34 IRSs, 75 ESTs, 4 STSs, and 4 phenotypic markers) for the Medaka Oryzias latipes, a teleost fish of the order Beloniformes. Linkage was determined using...

Solid-liquid phase boundaries of lens protein solutions.

Berland, C R, Thurston, G M, Kondo, M, Broide, M L, Pande, J, Ogun, O, ...

We report measurement of the solid-liquid phase boundary, or liquidus line, for aqueous solutions of three pure calf gamma-crystallin proteins: gamma II, gamma IIIa, and gamma IIIb. We also studied...

2,4-Dichlorophenoxybutyric acid-resistant mutants of Arabidopsis have defects in glyoxysomal fatty acid beta-oxidation.

Hayashi, M, Toriyama, K, Kondo, M, Nishimura, M

It has been demonstrated previously that 2,4-dichlorophenoxybutyric acid (2,4-DB) is metabolized to produce a herbicide, 2,4-D, by the action of peroxisomal fatty acid beta-oxidation in higher...

Expression of a vacuolar protein (VP24) in anthocyanin-producing cells of sweet potato in suspension culture.

Nozue, M, Yamada, K, Nakamura, T, Kubo, H, Kondo, M, Nishimura, M

VP24, an abundant protein of 24 kD, was found to accumulate in the anthocyanin-containing vacuoles of cells of sweet potato (Ipomoea batatas) in suspension culture. Light-induced expression of VP24...

Targeting and processing of a chimeric protein with the N-terminal presequence of the precursor to glyoxysomal citrate synthase.

Kato, A, Hayashi, M, Kondo, M, Nishimura, M

Glyoxysomal citrate synthase in pumpkin is synthesized as a precursor that has a cleavable presequence at its N-terminal end. To investigate the role of the presequence in the transport of the...

In vitro and in vivo antibacterial activities of carumonam (AMA-1080), a new N-sulfonated monocyclic beta-lactam antibiotic.

Imada, A, Kondo, M, Okonogi, K, Yukishige, K, Kuno, M

The in vitro and in vivo antibacterial activities of carumonam (AMA-1080), a synthetic sulfazecin derivative, were compared with those of aztreonam, cefoperazone, ceftazidime, and cefsulodin....

Novel morphological changes in gram-negative bacteria caused by combination of bulgecin and cefmenoxime.

Nakao, M, Yukishige, K, Kondo, M, Imada, A

The mode of action of bulgecin was investigated by examining its bactericidal and bacteriolytic activities, its effect on bacterial morphology, and its interaction with penicillin-binding proteins...

Cefmenoxime (SCE-1365), a novel broad-spectrum cephalosporin: in vitro and in vivo antibacterial activities.

Tsuchiya, K, Kondo, M, Kida, M, Nakao, M, Iwahi, T, Nishi, T, ...

The activity of cefmenoxime (SCE-1365), 7 beta-[2-(2-aminothiazol-4-yl)-(Z)-2-methoxyiminoacetamido]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid, was compared with that of...

In vitro and in vivo activities of SCE-2787, a new parenteral cephalosporin with a broad antibacterial spectrum.

Iwahi, T, Okonogi, K, Yamazaki, T, Shiki, S, Kondo, M, Miyake, A, ...

SCE-2787, a new cephalosporin having a condensed azolium moiety in the 3 position and an aminothiadiazolyl group in the 7 beta side chain, was evaluated for its in vitro and in vivo activities in...

Occurrence in Bacillus megaterium of uridine 5'-diphospho-N-acetylgalactosamine and uridine 5'-diphosphogalactosamine, intermediates in the biosynthesis of galactosamine-6-phosphate polymer.

Nishikawa, J, Tada, M, Takubo, Y, Nishihara, T, Kondo, M

We isolated two galactosamine derivatives from Bacillus megaterium sporulating cells by lectin affinity chromatography followed by DEAE-Sephadex A-25 chromatography. From chemical analyses and...

Effect of alanine-containing dipeptides on germination of Bacillus thiaminolyticus spores.

Watabe, K, Sano, K, Otani, M, Okada, Y, Kakiuchi, Y, Kondo, M

Stereoisomeric alanylalanine (Ala-Ala) derivatives were examined for their effects on germination of Bacillus thiaminolyticus spores. L-Ala-L-Ala and L-Ala-glycine were effective in inducing...

Differentiation of human immunodeficiency virus type 1 (HIV-1) infections with HIV-2-cross-reacting antibody from mixed infections with HIV-1 and HIV-2 by serological absorption test.

Imai, M, Hayashi, T, Kondo, M, Saito, T, Ito, A, Hayami, M, ...

The interpretation of dual seroreactivity with human immunodeficiency virus type 1 (HIV-1) and HIV-2 in blood samples is a serious problem facing AIDS researchers worldwide. Some samples of sera from...

Prior enrichment of human immunodeficiency virus DNA with probe DNA particles for efficient PCR diagnosis.

Tano, H, Fan, K, Kitajima, M A, Kasai, K, Tamatsukuri, S, Furuichi, Y, ...

We report here a novel method by which one can recover human immunodeficiency virus (HIV) DNA in a small volume (approximately 50 microliters) of solution from 8 ml of crude cell lysate which...

Effect of recombinant human interleukin-2 on the course of experimental chronic respiratory tract infection caused by Klebsiella pneumoniae in mice.

Iizawa, Y, Nishi, T, Kondo, M, Tsuchiya, K, Imada, A

The effect of recombinant human interleukin-2 (rIL-2) on the course of experimental chronic respiratory tract infection caused by Klebsiella pneumoniae in mice was examined. rIL-2 was administered...

Complete nucleotide sequence of the E. coli glutathione synthetase gsh-II.

Gushima, H, Yasuda, S, Soeda, E, Yokota, M, Kondo, M, Kimura, A

The nucleotide sequence of the cloned DNA, 1,478 bp in length coding for glutathione synthetase (GSH-II) of E. coli B has been determined. Amino acid and nucleotide sequence analyses have assigned...

Non-polyadenylated 22 s ribonucleoprotein particle is insensitive to translational inhibitor RNA of cryptobiotic gastrulae of Artemia salina.

De Herdt, E, Slegers, H, Piot, E, Kondo, M

A free cytoplasmic 22 S ribonucleoprotein particle exhibiting a major template activity in rabbit reticulocyte system has been identified in the cryptobiotic gastrulae of Artemia salina. This...

Messenger ribonucleoprotein complexes of cryptobiotic embryos of Artemia salina.

Slegers, H, Kondo, M

Poly(A)-containing ribonucleoprotein (poly(A)+-RNP) particles in the post-mitochondrial supernatant of cryptobiotic embryos of Artemia salina were characterized by hybridization to [3H]-poly(U). By...

Comparative in vitro activities of SCE-129, sulbenicillin, gentamicin, and dibekacin against Pseudomonas.

Tsuchiya, K, Kondo, M

Against sulbenicillin- and gentamicin-susceptible strains of Pseudomonas aeruginosa, SCE-129 was about 10 times more active than sulbenicillin and had a similar activity to gentamicin and dibekacin....

Diabetes due to secretion of a structurally abnormal insulin (insulin Wakayama). Clinical and functional characteristics of [LeuA3] insulin.

Nanjo, K, Sanke, T, Miyano, M, Okai, K, Sowa, R, Kondo, M, ...

We have identified a non-insulin-dependent diabetic patient with fasting hyperinsulinemia (90 microU/ml), an elevated insulin:C-peptide molar ratio (1.68; normal, 0.05-0.20), normal insulin...

Prevention of adoptively transferred diabetes in nonobese diabetic mice with IL-10-transduced islet-specific Th1 lymphocytes. A gene therapy model for autoimmune diabetes.

Moritani, M, Yoshimoto, K, Ii, S, Kondo, M, Iwahana, H, Yamaoka, T, ...

Four pancreatic islet-specific CD4+ helper T (Th) 1 (Th1) clones and two Th1 clones transduced with an SRalpha promoter-linked murine IL-10 (mIL-10) cDNA of 2.0-6.0 x 10(6) cells were adoptively...

Characterization of metallothionein cDNAs induced by cadmium in the nematode Caenorhabditis elegans.

Imagawa, M, Onozawa, T, Okumura, K, Osada, S, Nishihara, T, Kondo, M

cDNAs of metallothioneins (MTs) in the nematode Caenorhabditis elegans were characterized. The MT-II clone encodes 62 amino acid residues and the predicted Mr is 6462. The MT-I clone contains an...

Identification of the mRNA and polypeptide subunit for prostaglandin endoperoxide synthase from mouse mastocytoma P-815 cells.

Kondo, M, Koshihara, Y, Kawamura, M, Murota, S

Cloned mouse mastocytoma P-815.2-E-6 cells are barely able to synthesize prostaglandins because of a lack of prostaglandin endoperoxide synthase activity. However, the addition of sodium n-butyrate...

Role of nitric oxide in tachykinin-induced increase in potential difference of rabbit tracheal mucosa.

Tamaoki, J, Sakai, A, Kondo, M, Takemura, H, Konno, K

1. The effect of tachykinins on transepithelial potential difference (PD) of rabbit trachea and possible involvement of nitric oxide (NO) generation in vivo were investigated. 2. Perfusion of...

Biophysical characterization of Artemia salina (L.) extracellular haemoglobins.

Wood, E J, Barker, C, Moens, L, Jacob, W, Heip, J, Kondo, M

Sedimentation coefficients (s0 20,w) of 11.57 +/- 0.10 S and 11.52 +/- 0.09 S were assigned for Artemia salina (L.) extracellular haemoglobins II and III respectively. These values are not...

A cryptobiosis-specific 19S protein complex of Artemia salina gastrulae.

De Herdt, E, De Voeght, F, Clauwaert, J, Kondo, M, Slegers, H

The postribosomal supernatant of Artemia salina cryptobiotic embryos contains a large quantity of a 19S protein complex. An amount of 3.6 mg/g of cysts is measured by immunoprecipitation with...

Selective resistance to desiccation of nuclear ribonucleic acid synthesis in isolated nuclei of Artemia salina embryos during pre-emergence development.

Chaffoy, D D, Kondo, M

The developing gastrula embryos of Artemia salina are resistant to a complete redesiccation during a period of pre-emergence development. Isolated nuclei from these dehydrated embryos could retain a...

Characterization of the extracellular haemoglobins of Artemia salina.

Moens, L, Kondo, M

The following factors were measured for extracellular haemoglobins of Artemia salina: a minimal molecular weight of globin chain per haem group (based on the iron and haem contents), the absorption...

Preferential inhibition by poly(adenylic acid) of minus-strand synthesis by bacteriophage Qbeta ribonucleic acid replicase.

Kondo, M

Among the homopolymers examined, poly(A) was found to inhibit preferentially the synthesis of the minus strand by bacteriophage Qbeta RNA replicase in the presence of host factor. A specific...

Biosynthesis of Poly(3-Hydroxyalkanoic Acid) Copolymer from CO(inf2) in Pseudomonas acidophila through Introduction of the DNA Fragment Responsible for Chemolithoautotrophic Growth of Alcaligenes hydrogenophilus

Yagi, K., Miyawaki, I., Kayashita, A., Kondo, M., Kitano, Y., Murakami, Y., ...

Pseudomonas acidophila is a bacterial strain producing a poly(3-hydroxyalkanoic acid) (PHA) copolymer from low-molecular-weight organic compounds such as formate and acetate. The genes responsible...

A detailed linkage map of medaka, Oryzias latipes: comparative genomics and genome evolution.

Naruse, K, Fukamachi, S, Mitani, H, Kondo, M, Matsuoka, T, Kondo, S, ...

We mapped 633 markers (488 AFLPs, 28 RAPDs, 34 IRSs, 75 ESTs, 4 STSs, and 4 phenotypic markers) for the Medaka Oryzias latipes, a teleost fish of the order Beloniformes. Linkage was determined using...

Fluid phase destruction of C2hu by C[unk]1hu: III. Changes in activity for synthetic substrates upon cell binding, heat inactivation and interaction with C[unk]1INH

Kondo, M., Gigli, Irma, Austen, K. F.

The enzymatic efficiency of C[unk]1* for its natural substrates C4 and C2 or the synthetic substrates N-α-acetylglycyl-L-lysine methylester acetate (AGLMe), N-acetyl-L-arginine methylester (AAMe),...

Effect of S5P α-helix charge mutants on inactivation of hERG K+ channels

Clarke, C E, Hill, A P, Zhao, J, Kondo, M, Subbiah, R N, Campbell, T J, ...

The ether-à-go-go (EAG) family of voltage-gated K+ channels contains three subfamilies, EAG, ether-à-go-go related (ERG) and ether-à-go-go like (ELK). The human ether-à-go-go related gene (hERG)...

Role of active oxygen, lipid peroxidation, and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats.

Yoshikawa, T, Naito, Y, Kishi, A, Tomii, T, Kaneko, T, Iinuma, S, ...

The roles of active oxygen, lipid peroxidation, and the antioxidative defence mechanism in gastric mucosal injury induced by treatment with indomethacin in rats were investigated. The total area of...

Corticotropin releasing hormone in colonic mucosa in patients with ulcerative colitis.

Kawahito, Y, Sano, H, Mukai, S, Asai, K, Kimura, S, Yamamura, Y, ...

Corticotropin releasing hormone (CRH) is a key hormone in integrated response to stress, acting as the major regulator of the hypothalamic-pituitary-adrenal axis. Recently, local production of CRH...

Enzyme immunoassay of pancreatic oncofetal antigen (POA) as a marker of pancreatic cancer.

Nishida, K, Sugiura, M, Yoshikawa, T, Kondo, M

For the quantitative measurement of pancreatic oncofetal antigen (POA), an enzyme immunoassay for POA has been developed, and is based on the sandwich method using antibody-coupled glass beads and...

Possible paracrine growth of adenocarcinoma of the stomach induced by granulocyte colony stimulating factor produced by squamous cell carcinoma of the oesophagus

Ichiishi, E, Yoshikawa, T, Kogawa, T, Yoshida, N, Kondo, M

Synchronous cancers of the oesophagus and stomach diagnosed in a patient showing pronounced leucocytosis were examined for production of granulocyte colony stimulating factor (G-CSF) and expression...

Microsatellite instability in patients with multiple primary cancers of the gastrointestinal tract

Yamashita, K, Arimura, Y, Kurokawa, S, Itoh, F, Endo, T, Hirata, K, ...

BACKGROUND—Little is known about the genetic alterations in multiple primary cancers of the gastrointestinal tract. Microsatellite instability (MSI) is frequently observed in hereditary...

Postoperative thallium-201 myocardial images. Evidence of regression of right ventricular hypertrophy in man.

Yamazaki, H, Tsugu, T, Handa, S, Takagi, Y, Ohsuzu, F, Kondo, M, ...

Thallium-201 myocardial scintigraphic studies were performed on 24 patients with chronic right ventricular overload before and after surgical correction of haemodynamic overload. The ages of the...

High positive frequency of antibodies to metallothionein and heat shock protein 70 in sera of patients with metal allergy

JIN, G-B, NAKAYAMA, H, SHMYHLO, M, INOUE, S, KONDO, M, IKEZAWA, Z, ...

Two principal types of stress protein, heat shock proteins (hsps) and metallothionein (MT), are induced in cells responding to a variety of stresses. They play an important role in protecting cells...

Leaky phenotype of X-linked agammaglobulinaemia in a Japanese family

Kaneko, H, Kawamoto, N, Asano, T, Mabuchi, Y, Horikoshi, H, Teramoto, T, ...

X-linked agammaglobulinaemia (XLA) is an inherited immunodeficiency that is caused by a block in early B-cell differentiation. Whereas early B precursors in the bone marrow are present in substantial...

Effect of shear stress and a stable prostaglandin I2 analogue on adhesive interactions of colon cancer cells and endothelial cells

Yoshida, N, Yoshikawa, T, Nakagawa, S, Sakamoto, K, Nakamura, Y, Naito, Y, ...

In the process of cancer metastasis, adhesion between cancer cells and endothelial cells is an important early step. In the present study, the effects of shear stress and the adhesion molecules...

Role of Ca2+-activated K+ channel in epithelium-dependent relaxation of human bronchial smooth muscle

Tamaoki, J, Tagaya, E, Isono, K, Kondo, M, Konno, K

To elucidate whether K+ channels play a role in the action of epithelium-dependent bronchodilatation, we studied responses in human bronchial strips in the presence of indomethacin and...

Stimulation by menthol of Cl secretion via a Ca(2+)-dependent mechanism in canine airway epithelium.

Chiyotani, A., Tamaoki, J., Takeuchi, S., Kondo, M., Isono, K., Konno, K.

1. To investigate the effect of menthol on airway epithelial ion transport function, we studied the bioelectrical properties of canine cultured tracheal epithelium by Ussing's short-circuit technique...

Involvement of macrophage migration inhibitory factor (MIF) in the mechanism of tumor cell growth.

Takahashi, N., Nishihira, J., Sato, Y., Kondo, M., Ogawa, H., Ohshima, T., ...

BACKGROUND: Macrophage migration inhibitory factor (MIF) was recently rediscovered as a cytokine, pituitary hormone, and glucocorticoid-induced immunomodulator. MIF is constitutively expressed in...

Time of closure of ductus venosus in term and preterm neonates

Kondo, M, Itoh, S, Kunikata, T, Kusaka, T, Ozaki, T, Isobe, K, ...

AIM—To investigate the relation between gestational age, birth weight, and antenatal corticosteroid administration and the time of ductus venosus closure.
METHODS—Ninety eight neonates of 30-41...

p53 mutations in non-small-cell lung cancers occurring in individuals without a past history of active smoking.

Takagi, Y., Osada, H., Kuroishi, T., Mitsudomi, T., Kondo, M., Niimi, T., ...

Accumulating evidence suggests that the p53 gene is a good target for molecular epidemiological studies. We previously reported an association between the presence of p53 mutations and lifetime...

Treatment of hepatocellular carcinoma with major portal vein thrombosis by combined therapy with subcutaneous interferon-α and intra-arterial 5-fluorouracil; role of type 1 interferon receptor expression

Ota, H, Nagano, H, Sakon, M, Eguchi, H, Kondo, M, Yamamoto, T, ...

We previously reported the beneficial effects of combination therapy of interferon (IFN)-α/5-fluorouracil (FU) for advanced hepatocellular carcinoma (HCC) with tumour thrombi in the major portal...

Economic evaluation of chemoprevention of breast cancer with tamoxifen and raloxifene among high-risk women in Japan

Kondo, M, Hoshi, S-L, Toi, M

Raloxifene was approved for chemoprevention against breast cancer among high-risk women in addition to tamoxifen by the US Food and Drug Administration. This study aims to evaluate cost-effectiveness...