Pavlopoulos, Georgios A., Pafilis, Evangelos, Kuhn, M., Hooper, Sean D., Schneider, Reinhard
OnTheFly is a web-based application that applies biological named entity recognition to enrich Microsoft Office, PDF and plain text documents. The input files are converted into the HTML format and...
J. Abermann, A. Lambrecht, A. Fischer, M. Kuhn
In this study we apply a simple and reliable method to derive recent changes in glacier area and volume by taking advantage of high resolution LIDAR (light detection and ranging) DEMs (digital...
Date of Delivery: <31.12.04> Contents (2008)
J. Lagrange, Knowledgelab Unilon, A. Mariotti, M. Kuhn, J. -f
Rationale of this Document...................................................................... 3 TELMA Teams........................................................................................ 4
Two-photon contributions to the Rosenbluth cross-section in the Skyrme model (2008)
We study two-photon contributions to the elastic electron nucleon scattering within the Skyrme model. In particular we focus on the role of the anomaly that enters via the Wess-Zumino term and...
1. Bündelung des Wissens in einem Softwaresystem, das es erlaubt, (2008)
Mit Beiträgen Von, F. Schmidt, R. Grob, Ike Uni Stuttgart, M. Kuhn, ...
mittelständische
Benchmarking for Boundary Element Methods (2007)
Many new algorithms for solving partial differential equations numerically have been proposed and implemented during the last years. This development causes the need for tools that allow an objective...
Parallel 3D Maxwell Solvers based on Domain Decomposition Data Distribution (2007)
Ddm Preprint, G. Haase, M. Kuhn, U. Langer
this paper, we propose a unified approach to the parallelization of multigrid methods and domain decomposition methods. In order to develop a basic parallel Maxwell solver that can be used for more...
Preprocessing in BE/FE Domain Decomposition Methods (2007)
M. Goppold, G. Haase, B. Heise, M. Kuhn
The Domain Decomposition Method (DD) is a powerful tool for constructing efficient parallel solvers for Partial Differential Equationd (PDEs) which are well suited to run on Multiple Instruction...
A. Anw, A. Anwander, M. Kuhn, M. Kuhn, S. Reitzinger, S. Reitzinger, ...
A parallel algebraic multigrid solver for finite element method based source localization in the human brain by
The Application of Coupled BE/FE Formulations in Technical Magnetic Field Computations (2007)
We present a coupled Finite Element (FE)-- Boundary Element (BE) formulation based on Domain Decomposition (DD) ideas leading to a discrete system which can be solved naturally in parallel on MIMD...
Symmetric FE and FE--BE Formulations of 3D Magnetic Field Problems (2007)
In this paper, we present several formulations of 3D magneto-static problems designed
Parallel Solvers for Large-Scale, Coupled Finite and Boundary Element Equations (2007)
U. Langer, M. Kuhn, Johannes Kepler
The Domain Decomposition (DD) approach offers many opportunities to marry the advantages of the Finite Element Method (FEM) to those of the Boundary Element Method (BEM) in many practical...
DDM.org 37. Parallel 3D Maxwell Solvers based on Domain Decomposition Data Distribution (2007)
Tony Chan, Takashi Kako, Hideo Kawarada, Olivier Pironneau, G. Haase, M. Kuhn, ...
The most e#cient solvers for finite element (fe) equations are certainly multigrid, or multilevel methods, and domain decomposition methods using local multigrid solvers. Typically, the multigrid...
String 7-recent developments in the integration and prediction of protein interactions (2007)
Mering, C. Von, Jensen, L.J., Kuhn, M., Chaffron, S., Doerks, T., Kruger, B., ...
Information on protein–protein interactions is still mostly limited to a small number of model organisms, and originates from a wide variety of experimental and computational techniques. The...
The Relation Between Rigorous and Helmert's Definitions of Orthometric Heights (2006)
Santos, M. C., Vaníček, P., Featherstone, W. E., Kingdon, R., Ellmann, A., ...
Following our earlier definition of the rigorous orthometric height [J Geod 79(1-3):82?92 (2005)] we present the derivation and calculation of the differences between this and the Helmert orthometric...
Baran, I., Kuhn, M., Claessens, S.J., Featherstone, W.E., Holmes, S.A., Vanicek, P.
A synthetic [simulated] Earth gravity model(SEGM) of the geoid, gravity and topography has been constructed over Australia specifically for validating regional gravimetric geoid determination...
Height systems and vertical datums: a review in the Australian context (2006)
This paper reviews (without equations) the various definitions of height systems and vertical geodetic datum surfaces, together with their practical realisation for users in Australia. Excluding...
Baran, I., Kuhn, M., Claessens, S.J., Featherstone, W.E., Holmes, S.A., Vanicek, P.
A synthetic [simulated] Earth gravity model(SEGM) of the geoid, gravity and topography has been constructed over Australia specifically for validating regional gravimetric geoid determination...
Height systems and vertical datums: a review in the Australian context (2006)
This paper reviews (without equations) the various definitions of height systems and vertical geodetic datum surfaces, together with their practical realisation for users in Australia. Excluding...
Regal sowie Be- und Entladevorrichtung fuer Lagerbehaelter in und aus einem Hochregallager (2006)
Schroer, W., Kuhn, M., Koenemann, M., Ten Hompel, M., Schmidt, T.
WO 2006122751 A1 UPAB: 20061208 NOVELTY - The rack has two horizontally oriented lower shelves, and a frame stand pivotably connected with the shelves in such a manner that the shelves are...
Baran, I., Kuhn, M., Claessens, S.J., Featherstone, W.E., Holmes, S.A., Vanicek, P.
A synthetic [simulated] Earth gravity model(SEGM) of the geoid, gravity and topography has been constructed over Australia specifically for validating regional gravimetric geoid determination...
Height systems and vertical datums: a review in the Australian context (2006)
This paper reviews (without equations) the various definitions of height systems and vertical geodetic datum surfaces, together with their practical realisation for users in Australia. Excluding...
Zhao, CB, Hobbs, BE, Ord, A, Kuhn, M, Muhlhaus, HB, Peng, SL
Numerical methods are used to simulate the double-diffusion driven convective pore-fluid flow and rock alteration in three-dimensional fluid-saturated geological fault zones. The double diffusion is...
The Relation Between Rigorous and Helmert's Definitions of Orthometric Heights (2006)
Santos, M. C., Vaníček, P., Featherstone, W. E., Kingdon, R., Ellmann, A., ...
Following our earlier definition of the rigorous orthometric height [J Geod 79(1-3):82?92 (2005)] we present the derivation and calculation of the differences between this and the Helmert orthometric...
Zhao, CB, Hobbs, BE, Ord, A, Kuhn, M, Muhlhaus, HB, Peng, SL
Numerical methods are used to simulate the double-diffusion driven convective pore-fluid flow and rock alteration in three-dimensional fluid-saturated geological fault zones. The double diffusion is...
Makarynskyy, O, Makarynska, D, Kuhn, M, Featherstone, W E
The knowledge of sea level variations is of great importance in geoenvironmental and ocean-engineering applications. Estimations of sea level change with different warning times are of vital...
Makarynskyy, O, Makarynska, D, Kuhn, M, Featherstone, W E
The knowledge of sea level variations is of great importance in geoenvironmental and ocean-engineering applications. Estimations of sea level change with different warning times are of vital...
The rigorous determination of orthometric heights (2005)
Tenzer, R., Vanicek, P., Santos, M., Featherstone, W.E., Kuhn, M.
The main problem of the rigorous definition of the orthometric height is the evaluation of the mean value of the Earth's gravity acceleration along the plumbline within the topography. To find the...
The rigorous determination of orthometric heights (2005)
Tenzer, R., Vanicek, P., Santos, M., Featherstone, W.E., Kuhn, M.
The main problem of the rigorous definition of the orthometric height is the evaluation of the mean value of the Earth's gravity acceleration along the plumbline within the topography. To find the...
AN ELECTRONIC SYSTEM FOR MEASURING THE ELECTRICAL CHARACTERISTICS OF NONLINEAR DEVICES, (2005)
An electronic system for obtaining the electrical characteristics of non-linear devices is described. Three modes of operation provide the I-V curve of the sample and either the differential...
SOME ELECTRICAL PROPERTIES OF Te FILMS AND Al-Al2O3-Te TUNNEL JUNCTIONS, (2005)
Tellurium evaporated onto pyrex substrates at room temperature is a polycrystalline p-type semiconductor with an energy gap equal to that for a single crystal Te. Its conduction properties are...
Verfahren zur Handhabung und Lagerung von Stueckguetern (2005)
DE 10349469 A UPAB: 20050712 NOVELTY - Each pallet module (1) is the same size. The modules are rectangular, with hooks (6) on their long sides (5) to hold them together. The ends (4) are without...
Makarynskyy, O, Makarynska, D, Kuhn, M, Featherstone, W E
The knowledge of sea level variations is of great importance in geoenvironmental and ocean-engineering applications. Estimations of sea level change with different warning times are of vital...
The rigorous determination of orthometric heights (2005)
Tenzer, R., Vanicek, P., Santos, M., Featherstone, W.E., Kuhn, M.
The main problem of the rigorous definition of the orthometric height is the evaluation of the mean value of the Earth's gravity acceleration along the plumbline within the topography. To find the...
The rigorous determination of orthometric heights (2005)
Tenzer, R., Vanicek, P., Santos, M., Featherstone, Will, Kuhn, M.
The main problem of the rigorous definition of the orthometric height is the evaluation of the mean value of the Earth's gravity acceleration along the plumbline within the topography. To find the...
The rigorous determination of orthometric heights (2005)
Tenzer, R., Vanicek, P., Santos, M., Featherstone, Will, Kuhn, M.
The main problem of the rigorous definition of the orthometric height is the evaluation of the mean value of the Earth's gravity acceleration along the plumbline within the topography. To find the...
Makarynskyy, O., Kuhn, M., Featherstone, W.E.
Recently, a lot of effort has been put into estimating possible near-future changes (say, 10-100 years) in the Earth's abiotic system, especially changes induced by human activities. One of the most...
Featherstone, W E, Holmes, S A, Kirby, J F, Kuhn, M
The commonly adopted remove-compute-restore (RCR) technique for regional gravimetric geoid determination uses the maximum degree of a combined global geopotential model and regional gravity data via...
Featherstone, W E, Holmes, S A, Kirby, J F, Kuhn, M
The commonly adopted remove-compute-restore (RCR) technique for regional gravimetric geoid determination uses the maximum degree of a combined global geopotential model and regional gravity data via...
Makarynskyy, O., Kuhn, M., Featherstone, W.E.
Recently, a lot of effort has been put into estimating possible near-future changes (say, 10-100 years) in the Earth's abiotic system, especially changes induced by human activities. One of the most...
Beitrag zur Gestaltung multifunktionaler Lagersysteme (2004)
Das Verkehrsaufkommen in den Städten und Ballungszentren verzeichnet einen stetigen Zuwachs, dessen Tendenzen sich in den Zulassungszahlen für Personen- und Lastkraftwagen widerspiegeln. Zum einen...
Makarynskyy, O., Kuhn, M., Featherstone, W.E.
Recently, a lot of effort has been put into estimating possible near-future changes (say, 10-100 years) in the Earth's abiotic system, especially changes induced by human activities. One of the most...
Featherstone, W E, Holmes, S A, Kirby, J F, Kuhn, M
The commonly adopted remove-compute-restore (RCR) technique for regional gravimetric geoid determination uses the maximum degree of a combined global geopotential model and regional gravity data via...
Malthan, D., Dobler, H., Gaugel, T., Gajovic-Eichelmann, N., Ehrentreich-Förster, E., Bier, F.F., ...
DNA and protein microarrays are commonly used research tools in the growing field of genomics and proteomics, e.g. expression analysis. Although there are several onchip synthesis techniques...
Wolters,C. H., Kuhn,M., Anwander,A., Reitzinger,S.
Time plays an important role in medical and neuropsychological diagnosis and research. In the field of Electro- and MagnetoEncephaloGraphy (EEG/MEG) source localization, a current distribution in the...
Fast anisotropic high resolution finite element head modeling in EEG/MEG-source localization (2002)
Wolters,C. H., Kuhn,M., Anwander,A., Reitzinger,S.
Accuracy and time play an important role in EEG/MEG-source localization. High resolution finite element head modeling allows the inclusion of tissue conductivity inhomogeneities and anisotropies. The...
Wolters,C. H., Kuhn,M., Anwander,A., Reitzinger,S.
Time plays an important role in medical and neuropsychological diagnosis and research. In the field of Electro- and MagnetoEncephaloGraphy (EEG/MEG) source localization, a current distribution in the...
Fast anisotropic high resolution finite element head modeling in EEG/MEG-source localization (2002)
Wolters,C. H., Kuhn,M., Anwander,A., Reitzinger,S.
Accuracy and time play an important role in EEG/MEG-source localization. High resolution finite element head modeling allows the inclusion of tissue conductivity inhomogeneities and anisotropies. The...
Wolters, C. H., Kuhn, M., Anwander, A., Reitzinger, S.
Time plays an important role in medical and neuropsychological diagnosis and research. In the field of Electro- and MagnetoEncephaloGraphy (EEG/MEG) source localization, a current distribution in the...
Fast anisotropic high resolution finite element head modeling in EEG/MEG-source localization (2002)
Wolters, C. H., Kuhn, M., Anwander, A., Reitzinger, S.
Accuracy and time play an important role in EEG/MEG-source localization. High resolution finite element head modeling allows the inclusion of tissue conductivity inhomogeneities and anisotropies. The...
Fast anisotropic high resolution finite element head modeling in EEG/MEG-source localization (2002)
Wolters, Carsten Hermann, Kuhn, M., Anwander, Alfred, Reitzinger, S.
Understanding 20th century sea-level rise and projections for the future (2001)
Church, J., Gregory, J., Huybrechts, P., Kuhn, M., Lambeck, K., Nhuan, M. T., ...
Accuracy of emergency department bedside ultrasonography (2001)
Rowland, J. L., Kuhn, M., Bonnin, R. L. L., Davey, M. J., Langlois, Suzanne
Accuracy of emergency department bedside ultrasonography (2001)
Rowland, J. L., Kuhn, M., Bonnin, R. L. L., Davey, M. J., Langlois, S.
Accuracy of emergency department bedside ultrasonography (2001)
Rowland, J. L., Kuhn, M., Bonnin, R. L. L., Davey, M. J., Langlois, Suzanne
HNO3 Partitioning in Cirrus Clouds (1999)
Meilinger, S.K., Tsias, A., Dreiling, V., Kuhn, M., Feigl, C., Ziereis, H., ...
Um die Ausgestaltung von Innovationsprozessen zu optimieren, sind Erfolgsfaktoren richtungsweisend. Die Innovationsforschung hat in Studien dementsprechende Faktoren identifiziert. Jedoch sind diese...
Glacio-meteorological investigations on Vatnajökull, Iceland, summer 1996: an overview (1999)
Oerlemans, J., Björnsson, H., Kuhn, M., Obleitner, F., Palsson, F., Smeets, P., ...
We give an overview of a glacio-meteorological experiment carried out in the summer (melt season) of 1996 on the largest European ice cap, Vatnajökull, Iceland (area 8000 km2; altitude range: from...
HNO3 Partitioning in Cirrus Clouds. (1999)
Meilinger, S. K., Tsias, A., Dreiling, V., Kuhn, M., Feigl, Ch., Ziereis, H., ...
Performance of chemical mechanisms for the degration of biogenic VOCs. (1999)
Borrell, P. M., Borrell, P., Kuhn, M., Lindfors, V., Pöschl, U., Kuhlmann, R. Von, ...
Intercomparison of the gas-phase chemistry in several chemistry and transport models (1998)
Kuhn, M., Builtjes, P.J.H., Poppe, D., Simpson, D., Stockwell, W.R., Andersson-Sköld, Y., ...
An analysis of quasi-lagrangian observations of particle groth during the POLSTAR-1 campaign (1998)
Meilinger, S.K., Tsias, A., Peter, T., Dreiling, V., Kuhn, M., Ziereis, H., ...
During the POLSTAR-1 winter campaign conducted from Kiruna (Sweden) in 1998 (20 January - 6 February), measurements were made of gas-phase and total water vapour, gas-phase nitric acid, reactive...
Preprocessing for 2D FE-BE Domain Decomposition Methods (1998)
The non-overlapping Domain Decomposition (DD) method is a powerful tool for the coupling of Finite Element (FE) and Boundary Element (BE) methods. Moreover it provides a natural basis for...
Scenarios for modeling of multi-phase tropospheric chemistry. (1998)
Poppe, D., Ackermann, I., Bunz, H., Geiger, H., Herrmann, H., Kuhn, M., ...
2nd CMD Workshop (Subproject Chemical Mechanisms Development of EUROTRAC 2), Karlsruhe, September 23-25, 1998
Intercomparison of the gas-phase chemistry in several chemistry and transport models. (1998)
Kuhn, M., Builtjes, P.J.H., Poppe, D., Simpson, D., Stockwell, W.R., Andersson-Sköld, Y., ...
Atmospheric Environment, 32(1998) S.693-709
M3,2 and L3,2 XAFS of Au and Pt Nanoparticles on Porous Silicon (1997)
Coulthard, I., Bzowski, A., Sham, T., Heald, S., Kuhn, M.
XAFS measurements at both the M3,2 and L3,2 edges of Pt and Au as well as scanning electron microscopy studies have been carried out for a series of porous silicon specimens onto which fine particles...
Near-Field Measurements on Contrail Properties from Fuels with Different Sulfur Content (1997)
Petzold, A., Busen, R., Schröder, F.P., Baumann, R., Kuhn, M., Ström, J., ...
Microphysical properties of jet exhaust aerosol and contrails were studied in the near field of the emitting aircraft for different fuel sulfur contents. Measurements were performed behind two...
Experiments on Control Formation from Fuels with Different Sulfur Content (1997)
Busen, R., Hagen, D., Kuhn, M., Petzold, A., Schröder, F., Schumann, U., ...
Results from the IPCC photochemical model intercomparison (PhotoComp) (1997)
Olson, J., Prather, M., Berntsen, T., Carmichael, G., Chatfield, R., Connell, P., ...
A new mechanism for regional atmospheric chemistry modeling (1997)
Stockwell, W.R., Kirchner, F., Kuhn, M., Seefeld, S.
A new gas-phase chemical mechanism for the modeling of regional atmospheric chemistry, the "Regional Atmospheric Chemistry Mechanism (RACM) is presented. The mechanism is intended to be valid for...
M3,2 and L3,2 XAFS of Au and Pt Nanoparticles on Porous Silicon (1997)
Coulthard, I., Bzowski, A., Sham, T., Heald, S., Kuhn, M.
XAFS measurements at both the M3,2 and L3,2 edges of Pt and Au as well as scanning electron microscopy studies have been carried out for a series of porous silicon specimens onto which fine particles...
M3,2 and L3,2 XAFS of Au and Pt Nanoparticles on Porous Silicon (1997)
Coulthard, I., Bzowski, A., Sham, T., Heald, S., Kuhn, M.
XAFS measurements at both the M3,2 and L3,2 edges of Pt and Au as well as scanning electron microscopy studies have been carried out for a series of porous silicon specimens onto which fine particles...
Gleitzeitmodelle ohne Kernzeit im Schichtbetrieb (1996)
Reißer, M., Schmelzer, S.F., Kuhn, M.
The flexitime model developed including minimum staffing, short- and long-time accounts, allows the organization to adapt very quickly to the existing requirements. Both overtime as a result of...
Preprocessing in BE/FE Domain Decomposition Methods (1996)
Goppold Haase, G. Haase, B. Heise, M. Kuhn
The Domain Decomposition Method (DD) is a powerful tool for constructing efficient parallel solvers for Partial Differential Equationd (PDEs) which are well suited to run on Multiple Instruction...
Low temperature PVD for hard coating of dielectric materials (1995)
Leonhardt, G., Falz, M., Kuhn, M., Lunow, T., Lopez, E., Wilberg, R., ...
Adaptive Domain Decomposition Methods for Finite and Boundary Element Equations (1995)
G. Haase, B. Heise, M. Kuhn, U. Langer
The use of the FEM and BEM in different subdomains of a non--overlapping Domain Decomposition (DD) and their coupling over the coupling boundaries (interfaces) brings about several advantages in many...
FEMooBEM 3.0 -- A parallel solver for linear and nonlinear coupled FE/BE-equations (1994)
G. Haase, B. Heise, M. Jung, M. Kuhn, O. Steinbach
This documentation gives an overview of the libraries belonging to FEM
The circulating bioactive form of human guanylin is a high molecular weight peptide (10.3 kD) (1993)
Kuhn, M. (1), Raida, M. (1), Adermann, K. (1), Schulz-Knappe, P. (1), Gerzer, R., ...
High Resolution Laser Spectroscopy of Small Molecules and Clusters (1991)
V. Beutel, W. Demtröder, J. Gress, M. Kuhn, ...
The combination of high resolution laser spectroscopy in collimated cold molecular beams with mass selective detection allows investigations of rotationally resolved molecular spectra of selected...
Analysis of the human guanylin gene and the processing and cellular localization of the peptide.
Hill, O, Kuhn, M, Zucht, H D, Cetin, Y, Kulaksiz, H, Adermann, K, ...
The complete cell biological analysis of human guanylin, a recently discovered regulatory peptide, is offered in this investigation: (i) the nucleotide sequence of the gene, (ii) the isolation and...
Cetin, Y, Kuhn, M, Kulaksiz, H, Adermann, K, Bargsten, G, Grube, D, ...
Guanylin, a bioactive peptide, has recently been isolated from the intestine; this peptide activates intestinal guanylate cyclase (i.e., guanylate cyclase C) and thus is potentially involved in the...
Salmonella strain secreting active listeriolysin changes its intracellular localization.
Gentschev, I, Sokolovic, Z, Mollenkopf, H J, Hess, J, Kaufmann, S H, Kuhn, M, ...
We describe the construction of an attenuated Salmonella dublin aroA strain which secretes via the Escherichia coli hemolysin secretion machinery an active hybrid cytolysin consisting of...
Demuth, A, Goebel, W, Beuscher, H U, Kuhn, M
Cytokine and cytokine receptor mRNA expression was analyzed by PCR-assisted amplification of RNA extracted from bone marrow-derived macrophages (BMM phi) at different time points after infection with...
The present paper analyzes the cytokine response of mouse macrophages during infection by Listeria monocytogenes. The use of different mutants of L. monocytogenes impaired in various steps of the...
Structural and functional properties of the p60 proteins from different Listeria species.
Bubert, A, Kuhn, M, Goebel, W, Köhler, S
The major extracellular protein p60 of Listeria monocytogenes seems to be required for this microorganism's adherence to and invasion of 3T6 mouse fibroblasts but not for adherence to human...
Cloning of the Alcaligenes eutrophus alcohol dehydrogenase gene.
Kuhn, M, Jendrossek, D, Fründ, C, Steinbüchel, A, Schlegel, H G
Mutants of Alcaligenes eutrophus which are altered with respect to the utilization of 2,3-butanediol and acetoin were isolated after transposon mutagenesis. The suicide vehicle pSUP5011 was used to...
Hydrogen evolution by strictly aerobic hydrogen bacteria under anaerobic conditions.
Kuhn, M, Steinbüchel, A, Schlegel, H G
When strains and mutants of the strictly aerobic hydrogen-oxidizing bacterium Alcaligenes eutrophus are grown heterotrophically on gluconate or fructose and are subsequently exposed to anaerobic...
Hemolysin supports survival but not entry of the intracellular bacterium Listeria monocytogenes.
Kuhn, M, Kathariou, S, Goebel, W
The gram-positive bacterium Listeria monocytogenes is a facultative intracellular pathogen. The only known property of L. monocytogenes which has been shown to be involved in virulence is a...
Hauf, N, Goebel, W, Serfling, E, Kuhn, M
In the present study, we investigated the effect of Listeria monocytogenes infection on the cellular level of the transcription factors NF-kappa B, AP-1, and NF-IL6 in the macrophage-like cell line...
Schwan, W R, Demuth, A, Kuhn, M, Goebel, W
Listeria monocytogenes is a facultative intracellular organism that is capable of replicating within macrophage and macrophage-like cells. The species secretes a phosphatidylinositol-specific...
Mutants of Listeria monocytogenes were recently isolated which are impaired in the synthesis of a major extracellular protein (p60). As shown in this investigation, the p60 mutants have lost the...
Kuhn, M, Prévost, M C, Mounier, J, Sansonetti, P J
Listeria monocytogenes has the capacity to penetrate and multiply within professional and nonprofessional phagocytic cells, such as the Caco-2 human enterocytelike cell line. It was shown recently...
Schulz, S, Lopez, M J, Kuhn, M, Garbers, D L
Heat-stable enterotoxins (STa), which cause an acute secretory diarrhea, have been suggested to mediate their actions through the guanylyl cyclase-C (GC-C) receptor. The GC-C gene was disrupted by...
Novel Approach for Assessing Performance of PCR Cyclers Used for Diagnostic Testing
Schoder, D., Schmalwieser, A., Schauberger, G., Hoorfar, J., Kuhn, M., Wagner, M.
As part of a large international project for validation and standardization of PCR, the influence of thermocyclers on PCR was tested. Six brand-new, Peltier technology-driven 96-well thermocyclers...
Kuhn, M, Adermann, K, Jähne, J, Forssmann, W G, Rechkemmer, G
1. Mucosally added synthetic guanylin and Escherichia coli heat-stable enterotoxin (STa) increased short-circuit current (ISC) across isolated muscle-stripped human intestine in vitro. 2. Serosal...
Kuhn, M, Fuchs, M, Beck, F X, Martin, S, Jähne, J, Klempnauer, J, ...
1. Serosally added synthetic endothelin-1 (ET-1) increased short-circuit current (Isc) across isolated muscle-stripped human colonic mucosa in vitro. Bumetanide inhibited Isc responses, indicating...
Analysis of the human guanylin gene and the processing and cellular localization of the peptide.
Hill, O, Kuhn, M, Zucht, H D, Cetin, Y, Kulaksiz, H, Adermann, K, ...
The complete cell biological analysis of human guanylin, a recently discovered regulatory peptide, is offered in this investigation: (i) the nucleotide sequence of the gene, (ii) the isolation and...
Cetin, Y, Kuhn, M, Kulaksiz, H, Adermann, K, Bargsten, G, Grube, D, ...
Guanylin, a bioactive peptide, has recently been isolated from the intestine; this peptide activates intestinal guanylate cyclase (i.e., guanylate cyclase C) and thus is potentially involved in the...
Salmonella strain secreting active listeriolysin changes its intracellular localization.
Gentschev, I, Sokolovic, Z, Mollenkopf, H J, Hess, J, Kaufmann, S H, Kuhn, M, ...
We describe the construction of an attenuated Salmonella dublin aroA strain which secretes via the Escherichia coli hemolysin secretion machinery an active hybrid cytolysin consisting of...
Demuth, A, Goebel, W, Beuscher, H U, Kuhn, M
Cytokine and cytokine receptor mRNA expression was analyzed by PCR-assisted amplification of RNA extracted from bone marrow-derived macrophages (BMM phi) at different time points after infection with...
The present paper analyzes the cytokine response of mouse macrophages during infection by Listeria monocytogenes. The use of different mutants of L. monocytogenes impaired in various steps of the...
Structural and functional properties of the p60 proteins from different Listeria species.
Bubert, A, Kuhn, M, Goebel, W, Köhler, S
The major extracellular protein p60 of Listeria monocytogenes seems to be required for this microorganism's adherence to and invasion of 3T6 mouse fibroblasts but not for adherence to human...
Cloning of the Alcaligenes eutrophus alcohol dehydrogenase gene.
Kuhn, M, Jendrossek, D, Fründ, C, Steinbüchel, A, Schlegel, H G
Mutants of Alcaligenes eutrophus which are altered with respect to the utilization of 2,3-butanediol and acetoin were isolated after transposon mutagenesis. The suicide vehicle pSUP5011 was used to...
Hydrogen evolution by strictly aerobic hydrogen bacteria under anaerobic conditions.
Kuhn, M, Steinbüchel, A, Schlegel, H G
When strains and mutants of the strictly aerobic hydrogen-oxidizing bacterium Alcaligenes eutrophus are grown heterotrophically on gluconate or fructose and are subsequently exposed to anaerobic...
Hemolysin supports survival but not entry of the intracellular bacterium Listeria monocytogenes.
Kuhn, M, Kathariou, S, Goebel, W
The gram-positive bacterium Listeria monocytogenes is a facultative intracellular pathogen. The only known property of L. monocytogenes which has been shown to be involved in virulence is a...
Hauf, N, Goebel, W, Serfling, E, Kuhn, M
In the present study, we investigated the effect of Listeria monocytogenes infection on the cellular level of the transcription factors NF-kappa B, AP-1, and NF-IL6 in the macrophage-like cell line...
Schwan, W R, Demuth, A, Kuhn, M, Goebel, W
Listeria monocytogenes is a facultative intracellular organism that is capable of replicating within macrophage and macrophage-like cells. The species secretes a phosphatidylinositol-specific...
Mutants of Listeria monocytogenes were recently isolated which are impaired in the synthesis of a major extracellular protein (p60). As shown in this investigation, the p60 mutants have lost the...
Kuhn, M, Prévost, M C, Mounier, J, Sansonetti, P J
Listeria monocytogenes has the capacity to penetrate and multiply within professional and nonprofessional phagocytic cells, such as the Caco-2 human enterocytelike cell line. It was shown recently...
Schulz, S, Lopez, M J, Kuhn, M, Garbers, D L
Heat-stable enterotoxins (STa), which cause an acute secretory diarrhea, have been suggested to mediate their actions through the guanylyl cyclase-C (GC-C) receptor. The GC-C gene was disrupted by...
Novel Approach for Assessing Performance of PCR Cyclers Used for Diagnostic Testing
Schoder, D., Schmalwieser, A., Schauberger, G., Hoorfar, J., Kuhn, M., Wagner, M.
As part of a large international project for validation and standardization of PCR, the influence of thermocyclers on PCR was tested. Six brand-new, Peltier technology-driven 96-well thermocyclers...
Kuhn, M, Adermann, K, Jähne, J, Forssmann, W G, Rechkemmer, G
1. Mucosally added synthetic guanylin and Escherichia coli heat-stable enterotoxin (STa) increased short-circuit current (ISC) across isolated muscle-stripped human intestine in vitro. 2. Serosal...
Kuhn, M, Fuchs, M, Beck, F X, Martin, S, Jähne, J, Klempnauer, J, ...
1. Serosally added synthetic endothelin-1 (ET-1) increased short-circuit current (Isc) across isolated muscle-stripped human colonic mucosa in vitro. Bumetanide inhibited Isc responses, indicating...
Zhao, CB, Hobbs, BE, Ord, A, Kuhn, M, Muhlhaus, HB, Peng, SL
Numerical methods are used to simulate the double-diffusion driven convective pore-fluid flow and rock alteration in three-dimensional fluid-saturated geological fault zones. The double diffusion is...
Kuhn, M, Holtwick, R, Baba, H A, Perriard, J C, Schmitz, W, Ehler, E
Objective: To investigate how permanent inhibition of guanylyl cyclase A receptor (GC-A) affects cardiac function.
OnTheFly: a tool for automated document-based text annotation, data linking and network generation
Pavlopoulos, Georgios A., Pafilis, Evangelos, Kuhn, M., Hooper, Sean D., Schneider, Reinhard
OnTheFly is a web-based application that applies biological named entity recognition to enrich Microsoft Office, PDF and plain text documents. The input files are converted into the HTML format and...