M. Rubinstein

Details der Publikationsliste

Zeitraum

1958 - 2009

Anzahl

182

Co-Autoren

Submitted to IEEE Trans. EMC A Parallel Implementation of NEC for the Analysis of Large Structures (2008)

A. Rubinstein, F. Rachidi, M. Rubinstein, B. Reusser

parallelization is based on a bi-dimensional block-cyclic distribution of matrices on a rectangular processor grid, assuring a theoretically-optimal load balance among the processors. The code is...

Determination of lightning currents from far electromagnetic fields: Effect of a strike object (2007)

Bermudez, J. L., Rachidi, F., Janischewskyj, W., Shostak, V., Rubinstein, M., Pavanello, D., ...

We discuss in this paper the influence of the presence of an elevated strike object on the peak of the lightning return stroke current determined from remote field measurements. We develop analytical...

On the use of the equal area rule for the wire-grid representation of metallic surfaces (2006)

Rubinstein, A., Rostamzadeh, C., Rubinstein, M., Rachidi, F.

This paper presents a brief theoretical discussion on the issue of the wire-grid representation of surfaces using the Numerical Electromagnetics Code (NEC). Different approaches for the determination...

A physical interpretation of the equal area rule (2006)

Rubinstein, A., Rubinstein, M., Rachidi, F.

This paper presents a derivation and a physical interpretation of the equal area rule (EAR) for wire-grid simulation of surfaces. We propose a new procedure that leads to a formulation for obtaining...

On the evaluation of antenna-mode currents along transmission lines (2006)

Vukicevic, A., Rachidi, F., Rubinstein, M., Tkachenko, S. V.

In this paper, we derive an integral equation describing the antenna-mode currents along a two-wire transmission line (TL). We show that when the cross-sectional dimensions of the line are...

On the mechanisms of differential-mode to common-mode conversion in the broadband over power line (BPL) frequency band (2006)

Vukicevic, A., Rubinstein, M., Rachidi, F., Bermudez, J. L.

The conversion between the common and the differential modes is of great importance in the transmission of data over poorly balanced cables such as electrical wiring. In this paper, we have studied...

Review of the electromagnetic compatibility PLC work at the Swiss Federal Institute of Technology (Lausanne) and the University of Applied Sciences of Western Switzerland (Yverdon) (2006)

Vukicevic, A., Rubinstein, M., Rachidi, F., Bermudez, J. L., Schneider, M., Favre, P.

In this paper, we give an overview of the experimental and theoretical PLC- related research work carried out in close cooperation by the Swiss Federal Institute of Technology and the University Of...

Far-field-current relationship based on the TL model for lightning return strokes to elevated strike objects (2005)

Bermudez, J. L., Rachidi, F., Rubinstein, M., Janischewskyj, W., Shostak, V. O., Pavanello, D., ...

New general expressions relating lightning return stroke currents and far radiated electric and magnetic fields are proposed, taking into account the effect of an elevated strike object, whose...

Lightning strikes to elevated structures: influence grounding conditions on currents and electromagnetic fields (2005)

Petrache, E., Rachidi, F., Pavanello, D., Janischewskyj, W., Hussein, A. M., Rubinstein, M., ...

This paper presents an analysis of lightning return strokes to tall structures. The interaction of lightning with a tall structure is modeled using the antenna theory. The finite ground conductivity...

On wire-grid representation of solid metallic surfaces (2005)

Rubinstein, A., Rachidi, F., Rubinstein, M.

This paper deals with the wire-grid representation of metallic surfaces in numerical electromagnetic modeling. We discuss in particular the adequacy of the well known and widely used equal area rule...

Discussion on the assessment and mitigation of radiation from PLC networks (2005)

Rubinstein, M., Rachidi, F., Bermudez, J. L., Schneider, M., Vukicevic, A., Marthe, E.

Definitions are introduced to classify the regions of interest around PLC networks. An improvement to an existing technique for the reduction of emissions from PLC networks is proposed. Using...

Electromagnetic field radiated by lightning to tall towers: treatment of the discontinuity at the return stroke wave front (2004)

Pavanello, D., Rachidi, F., Rubinstein, M., Bermudez, J. L., Nucci, C. A.

Recently, engineering return stroke models were extended to take into account the presence of an elevated strike object, which was modeled as an ideal uniform transmission line. We show in this paper...

On the estimation of lightning peak currents from measured fields using lightning location systems (2004)

Rachidi, F., Bermudez, J. L., Rubinstein, M., Rakov, V. A.

Although, due to the high variability of key parameters such as the return-stroke speed, it is impossible to determine the lightning current accurately from the remotely measured electric or magnetic...

Influence of the height of an elevated strike object on the enhancement of lightning radiated fields (2003)

Bermudez, J. L., Rachidi, F., Janischewskyj, W., Hussein, A. M., Rubinstein, M., Pavanello, D., ...

We discuss in this paper the influence of the height of an elevated strike object on the magnitude of lightning radiated electric and magnetic fields. For the analysis, the transmission line (TL)...

On the use of transmission line theory to represent a nonuniform vertically-extended object struck by lightning (2003)

Hussein, A. M., Shostak, V., Chang, J. S., Bermudez, J. L., Rachidi, F., Chisholm, W. A., ...

In this study, we present an experimental validation of the transmission line representation of an elevated object struck by lightning. The experimental results are obtained using a reduced-scale...

A parallel implementation of NEC for the analysis of large structures (2003)

Rubinstein, A., Rachidi, F., Rubinstein, M., Reusser, B.

We present a new, parallel version of the numerical electromagnetics code (NEC). The parallelization is based on a bidimensional block-cyclic distribution of matrices on a rectangular processor grid,...

Increased splenocyte proliferative response and cytokine production in beta-endorphin-deficient mice (2002)

Refojo, D, Kovalovsky, D, Young, JI, Rubinstein, M, Holsboer, F, Reul, JMHM, ...

We used beta-endorphin-deficient mice as a novel approach to confirm the physiological role that opioid peptides play in the development or regulation of the immune system. We found that mice lacking...

On the enhancement of radiated electric and magnetic fields associated with lightning return strokes to tall structures (2001)

Bermudez, J. L., Rachidi, F., Janischewskyj, W., Hussein, A. M., Rubinstein, M., Nucci, C. A., ...

We propose in this paper new expressions relating lightning return stroke currents and far radiated electric and magnetic fields, taking into account the presence of an elevated strike object. The...

Enzymatic Conversion of Red Cells for Transfusion. (1998)

Goldstein,J., Grant,A., Orlando,J., Rubinstein,M.

Studies are reported on (1) Human in vivo Studies with Alapha-Galactosidase Converted Erythrocytes and (2) Alpha-N-Acetylgalactosaminidase and Conversion of Group A Cells.

Coexistence of localized and itinerant carriers near Tc in calcium-doped manganites (1998)

Jaime, M., Lin, P., Chun, S. H., Salamon, M. B., Dorsey, P., Rubinstein, M.

We explore the possibility that polaronic distortions in the paramagnetic phase of La$_{0.67}$Ca$_{0.33}$MnO$_3$ manganites persist in the ferromagnetic phase by considering the observed electrical...

On the influence of elevated strike objects on directly measured and indirectly estimated lightning currents (1998)

Guerrieri, S., Nucci, C. A., Rachidi, F., Rubinstein, M.

The knowledge of lightning current parameters comes essentially from direct measurements obtained using instrumented towers or triggered lightning, and from measurements of lightning electromagnetic...

Voltages induced on overhead lines by dart leaders and subsequent return strokes in natural and rocket-triggered lightning (1997)

Rachidi, F., Rubinstein, M., Guerrieri, S., Nucci, C. A.

The voltages induced by nearby lightning strikes are a major cause of outages in power distribution systems. We compute such voltages taking into account the effects of the dart leaders that precede...

High Temperature Thermopower in La_{2/3}Ca_{1/3}MnO_3 Films: Evidence for Polaronic Transport (1996)

Jaime, M., Salamon, M. B., Rubinstein, M., Treece, R. E., Horwitz, J. S., Chrisey, D. B.

Thermoelectric power, electrical resistivity and magnetization experiments, performed in the paramagnetic phase of La_{2/3}Ca_{1/3}MnO_3, provide evidence for polaron-dominated conduction in CMR...

Hall-Effect Sign Anomaly and Small-Polaronic Conduction in (La_{1-x}Gd_x)_{0.67}Ca_{0.33}MnO_3 (1996)

Jaime, M., Hardner, H. T., Salamon, M. B., Rubinstein, M., Dorsey, P., Emin, D.

The Hall coefficient of Gd-doped La_{2/3}Ca_{1/3}MnO_3 exhibits Arrhenius behavior over a temperature range from 2T_c to 4T_c, with an activation energy very close to 2/3 that of the electrical...

Overvoltages induced by lightning on overhead power and distribution lines with sag (1996)

Bermudez, J. L., Rubinstein, M., Rachidi, F., Ianoz, M.

Researchers working on the problem of the coupling of lightning electromagnetic fields to overhead lines have suggested that, if the formulation of the coupling problem given by Agrawal et al. is...

Extension of two return stroke models to consider the influence of elevated strike objects on the lightning return stroke current and the radiated electromagnetic field: comparison with experimental results (1996)

Guerrieri, S., Heidler, F., Nucci, C. A., Rachidi, F., Rubinstein, M.

The presence of an elevated strike object markedly affects both the measured lightning return stroke current and the radiated electromagnetic fields. The MTL and the TCS lightning return stroke...

On the influence of elevated strike objects on the lightning return stroke current and the distant electric field (1994)

Guerrieri, S., Nucci, C. A., Rachidi, F., Rubinstein, M.

Measurements of return stroke currents on instrumented towers reveal the existence of reflections at the tower bottom and top. In the paper, the effects of the reflections on both measured currents...

Modelling of lightning-induced voltages on overhead lines: recent developments (1994)

Nucci, C. A., Ianoz, M., Rachidi, F., Rubinstein, M., Tesche, F. M., Uman, M. A., ...

Return-stroke lightning models and coupling models permit a fairly good estimation of overvoltages induced by indirect lightning strokes. However, some discrepancies that still exist between measured...

Dynamics of telechelic ionomers. Can polymers diffuse large distances without relaxing stress ? (1993)

Leibler, L., Rubinstein, M., Colby, R.

We consider dynamics of entangled telechelic ionomers in the limit of strong association, where there are no free chain ends. Stress relaxation occurs in such a system by an exchange between pairs of...

Reinforcement of rubber by fractal aggregates (1993)

Witten, T., Rubinstein, M., Colby, R.

Rubber is commonly reinforced with colloidal aggregates of carbon or silica, whose structure has the scale invariance of a fractal object. Reinforced rubbers support large stresses, which often grow...

Scaling of megabase DNA undergoing gel electrophoresis (1993)

Obukhov, S., Rubinstein, M.

We present a simple description of configuration and dynamical properties of megabase DNA undergoing gel electrophoresis. The molecule moves in the field in the shape of a self-similar tree-like...

Dynamics of telechelic ionomers. Can polymers diffuse large distances without relaxing stress ? (1993)

Leibler, L., Rubinstein, M., Colby, R.

We consider dynamics of entangled telechelic ionomers in the limit of strong association, where there are no free chain ends. Stress relaxation occurs in such a system by an exchange between pairs of...

Reinforcement of rubber by fractal aggregates (1993)

Witten, T., Rubinstein, M., Colby, R.

Rubber is commonly reinforced with colloidal aggregates of carbon or silica, whose structure has the scale invariance of a fractal object. Reinforced rubbers support large stresses, which often grow...

Scaling of megabase DNA undergoing gel electrophoresis (1993)

Obukhov, S., Rubinstein, M.

We present a simple description of configuration and dynamical properties of megabase DNA undergoing gel electrophoresis. The molecule moves in the field in the shape of a self-similar tree-like...

Dynamics of telechelic ionomers. Can polymers diffuse large distances without relaxing stress ? (1993)

Leibler, L., Rubinstein, M., Colby, R.

We consider dynamics of entangled telechelic ionomers in the limit of strong association, where there are no free chain ends. Stress relaxation occurs in such a system by an exchange between pairs of...

Reinforcement of rubber by fractal aggregates (1993)

Witten, T., Rubinstein, M., Colby, R.

Rubber is commonly reinforced with colloidal aggregates of carbon or silica, whose structure has the scale invariance of a fractal object. Reinforced rubbers support large stresses, which often grow...

Scaling of megabase DNA undergoing gel electrophoresis (1993)

Obukhov, S., Rubinstein, M.

We present a simple description of configuration and dynamical properties of megabase DNA undergoing gel electrophoresis. The molecule moves in the field in the shape of a self-similar tree-like...

Relaxation of entangled polymers at the classical gel point (1990)

Rubinstein, M., Zurek, S., Mcleish, T.C.B., Ball, R.C.

We examine the relaxation behaviour of an entangled cross-linked polymer gel as it approaches the gel point in mean field (Flory-Stockmayer) percolation. The calculation is based on a tube model for...

Relaxation of entangled polymers at the classical gel point (1990)

Rubinstein, M., Zurek, S., Mcleish, T.C.B., Ball, R.C.

We examine the relaxation behaviour of an entangled cross-linked polymer gel as it approaches the gel point in mean field (Flory-Stockmayer) percolation. The calculation is based on a tube model for...

Relaxation of entangled polymers at the classical gel point (1990)

Rubinstein, M., Zurek, S., Mcleish, T.C.B., Ball, R.C.

We examine the relaxation behaviour of an entangled cross-linked polymer gel as it approaches the gel point in mean field (Flory-Stockmayer) percolation. The calculation is based on a tube model for...

MÖSSBAUER HYPERFINE FIELDS IN RBa2 (Cu0.97Fe0.03)3O7-x [R = Y, Pr, Er] (1988)

Rubinstein, M., Harford, M., Swartzendruber, L., Bennett, L.

Room temperature 57Fe Mössbauer spectra of RBa2 (Cu0.97Fe0.03)3O7-x [R = Y, Pr, Er] were obtained from samples with varying x. A magnetically-split hyperfine field spectrum was observed for the most...

MÖSSBAUER HYPERFINE FIELDS IN RBa2 (Cu0.97Fe0.03)3O7-x [R = Y, Pr, Er] (1988)

Rubinstein, M., Harford, M., Swartzendruber, L., Bennett, L.

Room temperature 57Fe Mössbauer spectra of RBa2 (Cu0.97Fe0.03)3O7-x [R = Y, Pr, Er] were obtained from samples with varying x. A magnetically-split hyperfine field spectrum was observed for the most...

MÖSSBAUER HYPERFINE FIELDS IN RBa2 (Cu0.97Fe0.03)3O7-x [R = Y, Pr, Er] (1988)

Rubinstein, M., Harford, M., Swartzendruber, L., Bennett, L.

Room temperature 57Fe Mössbauer spectra of RBa2 (Cu0.97Fe0.03)3O7-x [R = Y, Pr, Er] were obtained from samples with varying x. A magnetically-split hyperfine field spectrum was observed for the most...

Absence of opioid stress-induced analgesia in mice lacking beta-endorphin by site-directed mutagenesis.

Rubinstein, M, Mogil, J S, Japón, M, Chan, E C, Allen, R G, Low, M J

A physiological role for beta-endorphin in endogenous pain inhibition was investigated by targeted mutagenesis of the proopiomelanocortin gene in mouse embryonic stem cells. The tyrosine codon at...

Two antiviral proteins from tobacco: purification and characterization by monoclonal antibodies to human beta-interferon.

Edelbaum, O, Ilan, N, Grafi, G, Sher, N, Stram, Y, Novick, D, ...

Polyclonal antibodies to human beta-interferon reacted specifically with two plant proteins (gp22 and gp35) by Western blot analysis of crude protein extracts from tobacco leaves infected with...

Ligand-induced association of the type I interferon receptor components.

Cohen, B, Novick, D, Barak, S, Rubinstein, M

Two transmembrane polypeptides, IFNAR and IFN-alpha/Beta R, were previously identified as essential components of the type I interferon (IFN) receptor, but their interrelationship and role in ligand...

Introduction of a point mutation into the mouse genome by homologous recombination in embryonic stem cells using a replacement type vector with a selectable marker.

Rubinstein, M, Japón, M A, Low, M J

The introduction of small mutations instead of null alleles into the mouse genome has broad applications to the study of protein structure-function relationships and the creation of animal models of...

Production of hybridomas secreting monoclonal antibodies to the human leukocyte interferons.

Staehelin, T, Durrer, B, Schmidt, J, Takacs, B, Stocker, J, Miggiano, V, ...

Thirteen monoclonal antibodies to human leukocyte interferon have been obtained. They exhibit different patterns of binding to purified leukocyte interferon species that are consistent with the...

Human interferons protect plants from virus infection.

Orchansky, P, Rubinstein, M, Sela, I

Unfractionated human leukocyte interferon, as well as highly purified subspecies of this interferon, and a purified recombinant of human leukocyte interferon produced in bacteria are active in...

Interferon-dependent induction of mRNA for the major histocompatibility antigens in human fibroblasts and lymphoblastoid cells.

Fellous, M, Nir, U, Wallach, D, Merlin, G, Rubinstein, M, Revel, M

In human cells treated with interferons, there is an increase in the amount of HLA-A,B,C and beta 2-microglobulin exposed on the cell surface. We have used a cloned HLA-A,B,C cDNA probe to...

Amino acid sequence of a human leukocyte interferon.

Levy, W P, Rubinstein, M, Shively, J, Del Valle, U, Lai, C Y, Moschera, J, ...

The primary structures of three major species of human leukocyte interferon differ from the structure predicted from the DNA sequence of recombinants containing leukocyte interferon-coding regions....

Amino-terminal amino acid sequence of human leukocyte interferon.

Levy, W P, Shively, J, Rubinstein, M, Del Valle, U, Pestka, S

We report the amino-terminal sequence of the first 22 amino acids of human leukocyte interferon. These and other results indicate that human leukocyte interferon consists of many individual species....

Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary glands of transgenic mice.

Liu, B, Hammer, G D, Rubinstein, M, Mortrud, M, Low, M J

The proopiomelanocortin (POMC) gene is highly expressed in adult mouse pituitary anterior lobe corticotrophs and intermediate lobe melanotrophs. To identify the DNA elements important for this...

A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1.

Mohammadi, M, Honegger, A M, Rotin, D, Fischer, R, Bellot, F, Li, W, ...

Phospholipase C-gamma (PLC-gamma) is a substrate of the fibroblast growth factor receptor (FGFR; encoded by the flg gene) and other receptors with tyrosine kinase activity. It has been demonstrated...

Human leukocyte interferon: production, purification to homogeneity, and initial characterization.

Rubinstein, M, Rubinstein, S, Familletti, P C, Miller, R S, Waldman, A A, Pestka, S

A method of fractionating proteins by high-performance liquid partition chromatography has been developed and used for isolation and purification to homogeneity of one of the species of human...

Purification to homogeneity of camel pituitary pro-opiocortin, the common precursor of opioid peptides and corticotropin.

Kimura, S, Lewis, R V, Gerber, L D, Brink, L, Rubinstein, M, Stein, S, ...

Pro-opiocortin was purified from camel pituitaries by procedures including high-performance liquid chromatography. The precursor relationship of the pure protein to the opioid peptides and to...

High molecular weight opioid-containing proteins in striatum.

Lewis, R V, Stein, S, Gerber, L D, Rubinstein, M, Udenfriend, S

Striatal extracts of guinea pigs, rats, and cattle were found to contain two large proteins (greater than 40,000 and greater than 100,000 daltons) that on treatment with trypsin yield opioid peptides...

Characterization of pro-opiocortin, a precursor to opioid peptides and corticotropin.

Rubinstein, M, Stein, S, Udenfriend, S

The high molecular weight (approximately 30,000) precursor to opioid activity (pro-opiocortin) previously detected in extracts of rat pituitary was digested with trypsin and the resulting peptide...

Isolation and characterization of the opioid peptides from rat pituitary: beta-lipotropin.

Rubinstein, M, Stein, S, Gerber, L D, Udenfriend, S

Rat beta-lipotropin was isolated from 40 anterior pituitaries using high efficiency chromatography columns and sensitive fluorometric methods. The beta-lipotropin was characterized as to molecular...

Isolation and characterization of the opioid peptides from rat pituitary: beta-endorphin.

Rubinstein, M, Stein, S, Udenfriend, S

beta-Endorphin was isolated from 200 rat pituitaries by means of high-performance column chromatography, using sensitive fluorometric methods and a radioreceptor assay for opioid activity. The...

Monoclonal antibodies to human interferon-gamma: production, affinity purification and radioimmunoassay.

Novick, D, Eshhar, Z, Fischer, D G, Friedlander, J, Rubinstein, M

Human interferon-gamma (IFN-gamma) purified to electrophoretic homogeneity by a cation exchange h.p.l.c., was used for the development of monoclonal antibodies. Following immunization, spleen...

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT.

Zelzer, E, Levy, Y, Kahana, C, Shilo, B Z, Rubinstein, M, Cohen, B

Hypoxic stress induces the expression of genes associated with increased energy flux, including the glucose transporters Glut1 and Glut3, several glycolytic enzymes, nitric oxide synthase, tyrosine...

Absence of opioid stress-induced analgesia in mice lacking beta-endorphin by site-directed mutagenesis.

Rubinstein, M, Mogil, J S, Japón, M, Chan, E C, Allen, R G, Low, M J

A physiological role for beta-endorphin in endogenous pain inhibition was investigated by targeted mutagenesis of the proopiomelanocortin gene in mouse embryonic stem cells. The tyrosine codon at...

Two antiviral proteins from tobacco: purification and characterization by monoclonal antibodies to human beta-interferon.

Edelbaum, O, Ilan, N, Grafi, G, Sher, N, Stram, Y, Novick, D, ...

Polyclonal antibodies to human beta-interferon reacted specifically with two plant proteins (gp22 and gp35) by Western blot analysis of crude protein extracts from tobacco leaves infected with...

Ligand-induced association of the type I interferon receptor components.

Cohen, B, Novick, D, Barak, S, Rubinstein, M

Two transmembrane polypeptides, IFNAR and IFN-alpha/Beta R, were previously identified as essential components of the type I interferon (IFN) receptor, but their interrelationship and role in ligand...

Introduction of a point mutation into the mouse genome by homologous recombination in embryonic stem cells using a replacement type vector with a selectable marker.

Rubinstein, M, Japón, M A, Low, M J

The introduction of small mutations instead of null alleles into the mouse genome has broad applications to the study of protein structure-function relationships and the creation of animal models of...

Production of hybridomas secreting monoclonal antibodies to the human leukocyte interferons.

Staehelin, T, Durrer, B, Schmidt, J, Takacs, B, Stocker, J, Miggiano, V, ...

Thirteen monoclonal antibodies to human leukocyte interferon have been obtained. They exhibit different patterns of binding to purified leukocyte interferon species that are consistent with the...

Human interferons protect plants from virus infection.

Orchansky, P, Rubinstein, M, Sela, I

Unfractionated human leukocyte interferon, as well as highly purified subspecies of this interferon, and a purified recombinant of human leukocyte interferon produced in bacteria are active in...

Interferon-dependent induction of mRNA for the major histocompatibility antigens in human fibroblasts and lymphoblastoid cells.

Fellous, M, Nir, U, Wallach, D, Merlin, G, Rubinstein, M, Revel, M

In human cells treated with interferons, there is an increase in the amount of HLA-A,B,C and beta 2-microglobulin exposed on the cell surface. We have used a cloned HLA-A,B,C cDNA probe to...

Amino acid sequence of a human leukocyte interferon.

Levy, W P, Rubinstein, M, Shively, J, Del Valle, U, Lai, C Y, Moschera, J, ...

The primary structures of three major species of human leukocyte interferon differ from the structure predicted from the DNA sequence of recombinants containing leukocyte interferon-coding regions....

Amino-terminal amino acid sequence of human leukocyte interferon.

Levy, W P, Shively, J, Rubinstein, M, Del Valle, U, Pestka, S

We report the amino-terminal sequence of the first 22 amino acids of human leukocyte interferon. These and other results indicate that human leukocyte interferon consists of many individual species....

Identification of DNA elements cooperatively activating proopiomelanocortin gene expression in the pituitary glands of transgenic mice.

Liu, B, Hammer, G D, Rubinstein, M, Mortrud, M, Low, M J

The proopiomelanocortin (POMC) gene is highly expressed in adult mouse pituitary anterior lobe corticotrophs and intermediate lobe melanotrophs. To identify the DNA elements important for this...

A tyrosine-phosphorylated carboxy-terminal peptide of the fibroblast growth factor receptor (Flg) is a binding site for the SH2 domain of phospholipase C-gamma 1.

Mohammadi, M, Honegger, A M, Rotin, D, Fischer, R, Bellot, F, Li, W, ...

Phospholipase C-gamma (PLC-gamma) is a substrate of the fibroblast growth factor receptor (FGFR; encoded by the flg gene) and other receptors with tyrosine kinase activity. It has been demonstrated...

Human leukocyte interferon: production, purification to homogeneity, and initial characterization.

Rubinstein, M, Rubinstein, S, Familletti, P C, Miller, R S, Waldman, A A, Pestka, S

A method of fractionating proteins by high-performance liquid partition chromatography has been developed and used for isolation and purification to homogeneity of one of the species of human...

Purification to homogeneity of camel pituitary pro-opiocortin, the common precursor of opioid peptides and corticotropin.

Kimura, S, Lewis, R V, Gerber, L D, Brink, L, Rubinstein, M, Stein, S, ...

Pro-opiocortin was purified from camel pituitaries by procedures including high-performance liquid chromatography. The precursor relationship of the pure protein to the opioid peptides and to...

High molecular weight opioid-containing proteins in striatum.

Lewis, R V, Stein, S, Gerber, L D, Rubinstein, M, Udenfriend, S

Striatal extracts of guinea pigs, rats, and cattle were found to contain two large proteins (greater than 40,000 and greater than 100,000 daltons) that on treatment with trypsin yield opioid peptides...

Characterization of pro-opiocortin, a precursor to opioid peptides and corticotropin.

Rubinstein, M, Stein, S, Udenfriend, S

The high molecular weight (approximately 30,000) precursor to opioid activity (pro-opiocortin) previously detected in extracts of rat pituitary was digested with trypsin and the resulting peptide...

Isolation and characterization of the opioid peptides from rat pituitary: beta-lipotropin.

Rubinstein, M, Stein, S, Gerber, L D, Udenfriend, S

Rat beta-lipotropin was isolated from 40 anterior pituitaries using high efficiency chromatography columns and sensitive fluorometric methods. The beta-lipotropin was characterized as to molecular...

Isolation and characterization of the opioid peptides from rat pituitary: beta-endorphin.

Rubinstein, M, Stein, S, Udenfriend, S

beta-Endorphin was isolated from 200 rat pituitaries by means of high-performance column chromatography, using sensitive fluorometric methods and a radioreceptor assay for opioid activity. The...

Monoclonal antibodies to human interferon-gamma: production, affinity purification and radioimmunoassay.

Novick, D, Eshhar, Z, Fischer, D G, Friedlander, J, Rubinstein, M

Human interferon-gamma (IFN-gamma) purified to electrophoretic homogeneity by a cation exchange h.p.l.c., was used for the development of monoclonal antibodies. Following immunization, spleen...

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT.

Zelzer, E, Levy, Y, Kahana, C, Shilo, B Z, Rubinstein, M, Cohen, B

Hypoxic stress induces the expression of genes associated with increased energy flux, including the glucose transporters Glut1 and Glut3, several glycolytic enzymes, nitric oxide synthase, tyrosine...

Interferon-α induces interleukin-18 binding protein in chronic hepatitis C patients

KASER, A, NOVICK, D, RUBINSTEIN, M, SIEGMUND, B, ENRICH, B, KOCH, R O, ...

Interleukin-18 (IL-18), derived from macrophages and Kupffer cells, is the central pro-inflammatory cytokine leading to experimental liver failure. IL-18 binding protein (IL-18BP) is a circulating...

Single photon emission computed tomography in seizure disorders.

Denays, R, Rubinstein, M, Ham, H, Piepsz, A, Noël, P

Fourteen children with various seizure disorders were studied using a cerebral blood flow tracer, 123I iodoamphetamine (0.05 mCi/kg), and single photon emission computed tomography (SPECT). In the...