M. Sugiyama

Details der Publikationsliste

Zeitraum

1965 - 2008

Anzahl

119

Co-Autoren

Non-Gaussian Component Analysis: a Semi-parametric Framework for Linear Dimension Reduction (2008)

G. Blanchard, M. Sugiyama, M. Kawanabe, V. Spokoiny

We propose a new linear method for dimension reduction to identify non-Gaussian components in high dimensional data. Our method, NGCA (non-Gaussian component analysis), uses a very general...

Approximating the best linear unbiased estimator of non-Gaussian signals with Gaussian noise (2008)

Sugiyama, M., Kawanabe, M., Blanchard, G.

Obtaining the best linear unbiased estimator (BLUE) of noisy signals is a traditional but powerful approach to noise reduction. Explicitly computing the BLUE usually requires the prior knowledge of...

Direct importance estimation for covariate shift adaptation (2008)

Sugiyama, M., Suzuki, T., Nakajima, S., Kashima, H., Bunau, P. Von, Kawanabe, M.

A situation where training and test samples follow different input distributions is called covariate shift. Under covariate shift, standard learning methods such as maximum likelihood estimation are...

Adaptive Importance Sampling with Automatic Model Selection in Value Function Approximation (2008)

Hachiya, H., Akiyama, T., Sugiyama, M., Peters, J., Fox, D., Gomes, C. P.

Off-policy reinforcement learning is aimed at efficiently reusing data samples gathered in the past, which is an essential problem for physically grounded AI as experiments are usually prohibitively...

A new algorithm of non-Gaussian component analysis with radial kernel functions (2007)

Kawanabe, M., Sugiyama, M., Blanchard, G.

We consider high-dimensional data which contains a linear low-dimensional non-Gaussian structure contaminated with Gaussian noise, and discuss a method to identify this non-Gaussian subspace. For...

In search of non-Gaussian components of a high-dimensional distribution (2006)

Blanchard, G., Kawanabe, M., Sugiyama, M., Spokoiny, V.

Finding non-Gaussian components of high-dimensional data is an important preprocessing step for efficient information processing. This article proposes a new linear method to identify the...

REORIENTATION OF SOLVENT MOLECULES IN THE INTRAMOLECULAR CHARGE-TRANSFER REACTION OF SOLVATED CYANOPHENYLDISILANE CLUSTERS (2006)

Ishikawa, H., Sugiyama, M., Setaka, W., Kira, M., Mikami, N.

Author Institution: Department of Molecular Science and Material Engineering, Graduate School of Science and Technology, Kobe University, Kobe 657-8501, Japan; Department of Chemistry, Graduate...

Magnetic and junction properties of half-metallic double-perovskite thin films (2005)

Asano, H., Koduka, N., Imaeda, K., Sugiyama, M., Matsui, M.

This paper reports the magnetic, electrical, and microstructural properties of epitaxial thin films with an ordered double-perovskite structure. Sr2 FeMoO6 (SFMO) and Sr2 CrReO6 (SCRO) films have...

Resolving and modeling the effects of Fe and Mn redox cycling on trace metal behaviour in a seasonally anoxic lake. (2005)

Hamilton-Taylor, J., Smith, E.J., Davison, W., Sugiyama, M.

Vertical profiles of the dissolved and particulate (>0.45 μm) concentrations of Fe, Mn, Co, Ni, Cu, Pb, Al and Ba were determined on two occasions (14 and 22 August 1996) during summer...

Model selection under covariate shift (2005)

Sugiyama, M.

A common assumption in supervised learning is that the training and test input points follow the same probability distribution. However, this assumption is not fulfilled, e.g., in interpolation,...

Trading variance reduction with unbiasedness. The regularized subspace information criterion for robust model selection in kernel regression (2004)

Sugiyama, M., Kawanabe, M., Müller, K.R.

A well-known result by Stein (1956) shows that in particular situations, biased estimators can yield better parameter estimates than their generally preferred unbiased counterparts. This letter...

The subspace information criterion for infinite dimensional hypothesis spaces (2003)

Sugiyama, M.

A central problem in learning is selection of an appropriate model. This is typically done by estimating the unknown generalization errors of a set of models to be selected from and then choosing the...

Subspace information criterion for nonquadratic regularizers - model selection for sparse regressors (2002)

Tsuda, K., Sugiyama, M.

Nonquadratic regularizers, in particular the l/sub 1/ norm regularizer can yield sparse solutions that generalize well. In this work we propose the generalized subspace information criterion (GSIC)...

Selecting ridge parameters in infinite dimensional hypothesis spaces (2002)

Sugiyama, M.

Previously, an unbiased estimator of the generalization error called the subspace information criterion (SIC) was proposed for a finite dimensional reproducing kernel Hilbert space (RKHS). In this...

Subspace information criterion for non-quadratic regularizers: Model selection for sparse regressors (2000)

Tsuda, K., Sugiyama, M.

Non-quadratic regularizers, in particular the l1 norm regularizer can yield sparse solutions that generalize well. In this work we propose the Generalized Subspace Information Criterion (GSIC) that...

Subspace information criterion for non-quadratic regularizers: Model selection for sparse regressors (2000)

Tsuda, K., Sugiyama, M.

Non-quadratic regularizers, in particular the l1 norm regularizer can yield sparse solutions that generalize well. In this work we propose the Generalized Subspace Information Criterion (GSIC) that...

Simultaneous Optimization of Sample Points and Models (2000)

M. Sugiyama, Masashi Sugiyama, Hidemitsu Ogawa

this paper, we show that such an optimal set of sample points actually exists, and give a procedure for active learning with model selection. Supervised learning, generalization capability, active...

Properties of incremental projection learning (1999)

M. Sugiyama, H. Ogawa

We proposed a method of incremental projection learning which provides exactly the same generalization capability as that obtained by batch projection learning in the previous paper. However,...

Omicron'-Beta' Sialon Ceramics. (1998)

Asada, S., Ueki, M., Sugiyama, M.

Powders of Si3N4, Al2O3 and SiO2 were mixed with Y2O3 as sintering aid and hot-pressed to form o(prime)-beta(prime) sialon. During sintering, the o-prime phase preferentially precipitated in the...

MARTENSITE TRANSFORMATIONS IN Fe-Pd ALLOYS (1982)

Oshima, R., Sugiyama, M.

Martensite transformations in Fe-Pd alloys have been extensively studied by means of X-ray diffractometry, optical and electron microscopy and Mössbauer effect. Successive martensite transformations...

MARTENSITE TRANSFORMATIONS IN Fe-Pd ALLOYS (1982)

Oshima, R., Sugiyama, M.

Martensite transformations in Fe-Pd alloys have been extensively studied by means of X-ray diffractometry, optical and electron microscopy and Mössbauer effect. Successive martensite transformations...

MARTENSITE TRANSFORMATIONS IN Fe-Pd ALLOYS (1982)

Oshima, R., Sugiyama, M.

Martensite transformations in Fe-Pd alloys have been extensively studied by means of X-ray diffractometry, optical and electron microscopy and Mössbauer effect. Successive martensite transformations...

理解過程の分析(I教科共同研究) (1965)

杉山, 光男, Sugiyama, M.

国立情報学研究所で電子化したコンテンツを使用している。

Application of a Reverse Transcription-PCR for Identification and Differentiation of Aichi Virus, a New Member of the Picornavirus Family Associated with Gastroenteritis in Humans

Yamashita, T., Sugiyama, M., Tsuzuki, H., Sakae, K., Suzuki, Y., Miyazaki, Y.

Aichi viruses isolated in Vero cells from seven patients in five gastroenteritis outbreaks in Japan, five Japanese returning from Southeast Asian countries, and five local children in Pakistan with...

Cloning and characterization of a gene (UVR3) required for photorepair of 6-4 photoproducts in Arabidopsis thaliana.

Nakajima, S, Sugiyama, M, Iwai, S, Hitomi, K, Otoshi, E, Kim, S T, ...

UV radiation induces two major classes of pyrimidine dimers: the pyrimidine [6-4] pyrimidone photoproduct (6-4 product) and the cyclobutane pyrimidine dimer (CPD). Many organisms produce enzymes,...

Cloning and characterization of polyphenol oxidase cDNAs of Phytolacca americana.

Joy, R W, Sugiyama, M, Fukuda, H, Komamine, A

Two cDNA clones encoding polyphenol oxidases were isolated from a cDNA library constructed from a log-phase suspension culture of Phytolacca americana (pokeweed) producing betalains. The clones...

Changes in the activity and mRNA of cinnamyl alcohol dehydrogenase during tracheary element differentiation in zinnia.

Sato, Y, Watanabe, T, Komamine, A, Hibino, T, Shibata, D, Sugiyama, M, ...

Changes in the enzymatic activity of cinnamyl alcohol dehydrogenase (CAD) and in the expression of a gene for CAD during tracheary element (TE) differentiation were investigated in cultures of single...

Isolation of Temperature-Sensitive Mutants of Arabidopsis thaliana That Are Defective in the Redifferentiation of Shoots.

Yasutani, I., Ozawa, S., Nishida, T., Sugiyama, M., Komamine, A.

Three temperature-sensitive mutants of Arabidopsis thaliana that were defective in the redifferentiation of shoots were isolated as tools for the study of organogenesis. M3 lines were constructed by...

Cloning and sequence analysis of genes encoding xylanases and acetyl xylan esterase from Streptomyces thermoviolaceus OPC-520.

Tsujibo, H, Ohtsuki, T, Iio, T, Yamazaki, I, Miyamoto, K, Sugiyama, M, ...

Three genes encoding two types of xylanases (STX-I and STX-II) and an acetyl xylan esterase (STX-III) from Streptomyces thermoviolaceus OPC-520 were cloned, and their DNA sequences were determined....

A new competitive enzyme-linked immunosorbent assay demonstrates adequate immune levels to rabies virus in compulsorily vaccinated Japanese domestic dogs.

Sugiyama, M, Yoshiki, R, Tatsuno, Y, Hiraga, S, Itoh, O, Gamoh, K, ...

A competitive enzyme-linked immunosorbent assay (c-ELISA) was developed as an alternative to the viral neutralization (VN) test for rapid and simple detection of antibodies to rabies virus. The...

A mutation at proline-115 in the A-factor receptor protein of Streptomyces griseus abolishes DNA-binding ability but not ligand-binding ability.

Onaka, H, Sugiyama, M, Horinouchi, S

A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) and its specific receptor protein (ArpA) are required for streptomycin production and aerial mycelium formation in Streptomyces griseus....

Fosfomycin kinetics after intravenous and oral administration to human volunteers.

Goto, M, Sugiyama, M, Nakajima, S, Yamashina, H

The pharmacokinetics of fosfomycin, administered intravenously and orally at two different doses (20 and 40 mg/kg of body weight), was studied in seven volunteers. The elimination profile of this...

Pharmacokinetic studies with dibekacin, a new aminoglycoside, after intravenous and intramuscular administration to human volunteers.

Goto, M, Sugiyama, M, Ishizaki, T

The pharmacokinetics of dibekacin, a new aminoglycoside antibiotic, was studied in volunteers given the same dose (100 mg) intramuscularly on two separate occasions and intravenously at two different...

Non-invasive detection of bladder cancer by identification of abnormal CD44 proteins in exfoliated cancer cells in urine

Sugiyama, M, Woodman, A, Sugino, T, Crowley, S, Ho, K, Smith, J, ...

Aims—To investigate the expression of CD44 proteins in exfoliated urothelial cells and in tumour tissues from bladder cancer patients. A further objective was to evaluate the diagnostic potential...

Isolation and characterisation of antibodies which specifically recognise the peptide encoded by exon 7 (v2) of the human CD44 gene

Borgya, A, Woodman, A, Sugiyama, M, Donié, F, Kopetzki, E, Matsumura, Y, ...

Aims—Exon 7 of the human CD44 gene is overexpressed in many commonly occurring carcinomas. The aim of the study was to explore the diagnostic and therapeutic potential of this frequent abnormality.

Intraductal papillary mucinous tumors of the pancreas: imaging studies and treatment strategies.

Sugiyama, M, Atomi, Y

OBJECTIVE: We analyzed clinicopathologic and imaging features and the prognosis of intraductal papillary mucinous tumor (IPMT) of the pancreas to identify imaging findings indicative of malignancy...

Differential diagnosis of small polypoid lesions of the gallbladder: the value of endoscopic ultrasonography.

Sugiyama, M, Xie, X Y, Atomi, Y, Saito, M

OBJECTIVE: To evaluate the accuracy of endoscopic ultrasonography (EUS) in making a differential diagnosis of small (< or =20 mm) polypoid lesions of the gallbladder. SUMMARY BACKGROUND DATA:...

Treatment of choledocholithiasis in patients with liver cirrhosis. Surgical treatment or endoscopic sphincterotomy?

Sugiyama, M, Atomi, Y, Kuroda, A, Muto, T

OBJECTIVE: The clinical features of choledocholithiasis were analyzed in cirrhotic patients. The outcomes of surgical treatment and endoscopic sphincterotomy (EST) in this situation were compared and...

Percutaneous transhepatic bile drainage.

Mori, K, Misumi, A, Sugiyama, M, Okabe, M, Matsuoka, T

Percutaneous transhepatic bile drainage was performed in 13 patients with obstructive jaundice, using a combination of the PTC technique and a Seldinger angiography catheter. In 11 cases, the outflow...

Effects of vitamins on chromium(VI)-induced damage.

Sugiyama, M

The effects of vitamin E and vitamin B2 on DNA damage and cellular reduction of chromium(VI) were investigated using Chinese hamster V-79 cells. Pretreatment with alpha-tocopherol succinate (vitamin...

DNA single-strand breaks and cytotoxicity induced by chromate(VI), cadmium(II), and mercury(II) in hydrogen peroxide-resistant cell lines.

Tsuzuki, K, Sugiyama, M, Haramaki, N

The induction of cytotoxicity and DNA single-strand breaks by chromium(VI), cadmium(II), and mercury(II) were compared in H2O2-resistant Chinese hamster ovary (CHO(R)) cells and parental (CHO(P))...

Role of paramagnetic chromium in chromium(VI)-induced damage in cultured mammalian cells.

Sugiyama, M

Chromium(VI) compounds are known to be potent toxic and carcinogenic agents. Because chromium(VI) is easily taken up by cells and is subsequently reduced to chromium(III), the formation of...

Application of a Reverse Transcription-PCR for Identification and Differentiation of Aichi Virus, a New Member of the Picornavirus Family Associated with Gastroenteritis in Humans

Yamashita, T., Sugiyama, M., Tsuzuki, H., Sakae, K., Suzuki, Y., Miyazaki, Y.

Aichi viruses isolated in Vero cells from seven patients in five gastroenteritis outbreaks in Japan, five Japanese returning from Southeast Asian countries, and five local children in Pakistan with...

Cloning and characterization of a gene (UVR3) required for photorepair of 6-4 photoproducts in Arabidopsis thaliana.

Nakajima, S, Sugiyama, M, Iwai, S, Hitomi, K, Otoshi, E, Kim, S T, ...

UV radiation induces two major classes of pyrimidine dimers: the pyrimidine [6-4] pyrimidone photoproduct (6-4 product) and the cyclobutane pyrimidine dimer (CPD). Many organisms produce enzymes,...

Cloning and characterization of polyphenol oxidase cDNAs of Phytolacca americana.

Joy, R W, Sugiyama, M, Fukuda, H, Komamine, A

Two cDNA clones encoding polyphenol oxidases were isolated from a cDNA library constructed from a log-phase suspension culture of Phytolacca americana (pokeweed) producing betalains. The clones...

Changes in the activity and mRNA of cinnamyl alcohol dehydrogenase during tracheary element differentiation in zinnia.

Sato, Y, Watanabe, T, Komamine, A, Hibino, T, Shibata, D, Sugiyama, M, ...

Changes in the enzymatic activity of cinnamyl alcohol dehydrogenase (CAD) and in the expression of a gene for CAD during tracheary element (TE) differentiation were investigated in cultures of single...

Isolation of Temperature-Sensitive Mutants of Arabidopsis thaliana That Are Defective in the Redifferentiation of Shoots.

Yasutani, I., Ozawa, S., Nishida, T., Sugiyama, M., Komamine, A.

Three temperature-sensitive mutants of Arabidopsis thaliana that were defective in the redifferentiation of shoots were isolated as tools for the study of organogenesis. M3 lines were constructed by...

Cloning and sequence analysis of genes encoding xylanases and acetyl xylan esterase from Streptomyces thermoviolaceus OPC-520.

Tsujibo, H, Ohtsuki, T, Iio, T, Yamazaki, I, Miyamoto, K, Sugiyama, M, ...

Three genes encoding two types of xylanases (STX-I and STX-II) and an acetyl xylan esterase (STX-III) from Streptomyces thermoviolaceus OPC-520 were cloned, and their DNA sequences were determined....

A new competitive enzyme-linked immunosorbent assay demonstrates adequate immune levels to rabies virus in compulsorily vaccinated Japanese domestic dogs.

Sugiyama, M, Yoshiki, R, Tatsuno, Y, Hiraga, S, Itoh, O, Gamoh, K, ...

A competitive enzyme-linked immunosorbent assay (c-ELISA) was developed as an alternative to the viral neutralization (VN) test for rapid and simple detection of antibodies to rabies virus. The...

A mutation at proline-115 in the A-factor receptor protein of Streptomyces griseus abolishes DNA-binding ability but not ligand-binding ability.

Onaka, H, Sugiyama, M, Horinouchi, S

A-factor (2-isocapryloyl-3R-hydroxymethyl-gamma-butyrolactone) and its specific receptor protein (ArpA) are required for streptomycin production and aerial mycelium formation in Streptomyces griseus....

Fosfomycin kinetics after intravenous and oral administration to human volunteers.

Goto, M, Sugiyama, M, Nakajima, S, Yamashina, H

The pharmacokinetics of fosfomycin, administered intravenously and orally at two different doses (20 and 40 mg/kg of body weight), was studied in seven volunteers. The elimination profile of this...

Pharmacokinetic studies with dibekacin, a new aminoglycoside, after intravenous and intramuscular administration to human volunteers.

Goto, M, Sugiyama, M, Ishizaki, T

The pharmacokinetics of dibekacin, a new aminoglycoside antibiotic, was studied in volunteers given the same dose (100 mg) intramuscularly on two separate occasions and intravenously at two different...

Non-invasive detection of bladder cancer by identification of abnormal CD44 proteins in exfoliated cancer cells in urine

Sugiyama, M, Woodman, A, Sugino, T, Crowley, S, Ho, K, Smith, J, ...

Aims—To investigate the expression of CD44 proteins in exfoliated urothelial cells and in tumour tissues from bladder cancer patients. A further objective was to evaluate the diagnostic potential...

Isolation and characterisation of antibodies which specifically recognise the peptide encoded by exon 7 (v2) of the human CD44 gene

Borgya, A, Woodman, A, Sugiyama, M, Donié, F, Kopetzki, E, Matsumura, Y, ...

Aims—Exon 7 of the human CD44 gene is overexpressed in many commonly occurring carcinomas. The aim of the study was to explore the diagnostic and therapeutic potential of this frequent abnormality.

Intraductal papillary mucinous tumors of the pancreas: imaging studies and treatment strategies.

Sugiyama, M, Atomi, Y

OBJECTIVE: We analyzed clinicopathologic and imaging features and the prognosis of intraductal papillary mucinous tumor (IPMT) of the pancreas to identify imaging findings indicative of malignancy...

Differential diagnosis of small polypoid lesions of the gallbladder: the value of endoscopic ultrasonography.

Sugiyama, M, Xie, X Y, Atomi, Y, Saito, M

OBJECTIVE: To evaluate the accuracy of endoscopic ultrasonography (EUS) in making a differential diagnosis of small (< or =20 mm) polypoid lesions of the gallbladder. SUMMARY BACKGROUND DATA:...

Treatment of choledocholithiasis in patients with liver cirrhosis. Surgical treatment or endoscopic sphincterotomy?

Sugiyama, M, Atomi, Y, Kuroda, A, Muto, T

OBJECTIVE: The clinical features of choledocholithiasis were analyzed in cirrhotic patients. The outcomes of surgical treatment and endoscopic sphincterotomy (EST) in this situation were compared and...

Percutaneous transhepatic bile drainage.

Mori, K, Misumi, A, Sugiyama, M, Okabe, M, Matsuoka, T

Percutaneous transhepatic bile drainage was performed in 13 patients with obstructive jaundice, using a combination of the PTC technique and a Seldinger angiography catheter. In 11 cases, the outflow...

Effects of vitamins on chromium(VI)-induced damage.

Sugiyama, M

The effects of vitamin E and vitamin B2 on DNA damage and cellular reduction of chromium(VI) were investigated using Chinese hamster V-79 cells. Pretreatment with alpha-tocopherol succinate (vitamin...

DNA single-strand breaks and cytotoxicity induced by chromate(VI), cadmium(II), and mercury(II) in hydrogen peroxide-resistant cell lines.

Tsuzuki, K, Sugiyama, M, Haramaki, N

The induction of cytotoxicity and DNA single-strand breaks by chromium(VI), cadmium(II), and mercury(II) were compared in H2O2-resistant Chinese hamster ovary (CHO(R)) cells and parental (CHO(P))...

Role of paramagnetic chromium in chromium(VI)-induced damage in cultured mammalian cells.

Sugiyama, M

Chromium(VI) compounds are known to be potent toxic and carcinogenic agents. Because chromium(VI) is easily taken up by cells and is subsequently reduced to chromium(III), the formation of...

Amidolytic and peptidolytic activities of immunoglobulin G present in sera from patients with rheumatoid arthritis, Sjogren's syndrome and systemic lupus erythematosus.

Matsuura, K, Ikoma, S, Sugiyama, M, Funauchi, M, Sinohara, H

Polyclonal immunoglobulin G (IgG) from healthy subjects was found to be capable of hydrolyzing carbobenzoxy-Val-Gly-Arg-p-nitroanilide (a synthetic chromogenic substrate for trypsin) and...

Localisation of apoptosis and expression of apoptosis related proteins in the synovium of patients with rheumatoid arthritis.

Sugiyama, M, Tsukazaki, T, Yonekura, A, Matsuzaki, S, Yamashita, S, Iwasaki, K

OBJECTIVES: To investigate whether apoptosis occurs in the synovium of rheumatoid arthritis (RA), and the intermediate molecules operating in this process. METHODS: DNA fragmentation was detected by...

Analysis of anomalous CD44 gene expression in human breast, bladder, and colon cancer and correlation of observed mRNA and protein isoforms.

Woodman, A. C., Sugiyama, M., Yoshida, K., Sugino, T., Borgya, A., Goodison, S., ...

Many studies have now demonstrated disorganized overexpression of the CD44 gene in various types of human malignant tumors, and this abnormality has emerged as an interesting candidate marker for...

Longterm effects of endoscopic sphincterotomy on gall bladder motility.

Sugiyama, M, Atomi, Y

BACKGROUND: Some of patients with an intact gall bladder develop acute cholecystitis or have gall bladder stone formation after endoscopic sphincterotomy. Endoscopic sphincterotomy may affect gall...

Endoscopic ultrasonography for differential diagnosis of polypoid gall bladder lesions: analysis in surgical and follow up series

Sugiyama, M, Atomi, Y, Yamato, T

BACKGROUND—Differential diagnosis is often difficult for small (⩽20 mm) polypoid lesions of the gall bladder.
AIM—To assess the diagnostic accuracy of endoscopic ultrasonography (EUS) for...

The beneficial effects of treatment with all-trans-retinoic acid plus corticosteroid on autoimmune nephritis in NZB/WF1 mice

Nozaki, Y, Yamagata, T, Yoo, B-S, Sugiyama, M, Ikoma, S, Kinoshita, K, ...

Corticosteroids are highly effective anti-inflammatory or immunosuppressive drugs used commonly to treat human systemic lupus erythematosus (SLE). All-trans-retinoic acid (ATRA), which belongs to a...

Endoscopic retreatment of recurrent choledocholithiasis after sphincterotomy

Sugiyama, M, Suzuki, Y, Abe, N, Masaki, T, Mori, T, Atomi, Y

Background: Endoscopic sphincterotomy (ES) carries a substantial risk of recurrent choledocholithiasis but retreatment with endoscopic retrograde cholangiopancreatography (ERCP) is safe and feasible....

Matrilysin (MMP-7) as a significant determinant of malignant potential of early invasive colorectal carcinomas

Masaki, T, Matsuoka, H, Sugiyama, M, Abe, N, Goto, A, Sakamoto, A, ...

Matrix metalloproteinases play a crucial role in tumour invasion and mestasis. Matrilysin (MMP-7) has been shown to correlate with nodal or distant metastasis in colorectal carcinomas; however, its...