Mareke Oley

Identifizierung von Zielproteasen für das multifunktionelle Serpin-Gen Spn4 (2006)

Oley, Mareke

Serpine sind metastabile Proteaseinhibitoren, die ihre Zielenzyme irreversibel hemmen. Sie besitzen eine exponierte Schleife (reactive centre loop, RCL), die der Protease als Substrat präsentiert...

A proprotein convertase-inhibiting serpin with an endoplasmic reticulum targeting signal from Branchiostoma lanceolatum, a close relative of vertebrates

Bentele, Caterina, Krüger, Olaf, Tödtmann, Ulf, Oley, Mareke, Ragg, Hermann

Lancelets are considered to take a key position in the evolution of lineages leading to vertebrates. Herein, a serpin from the lancelet Branchiostoma lanceolatum, Bl-Spn1, was identified that...

A proprotein convertase-inhibiting serpin with an endoplasmic reticulum targeting signal from Branchiostoma lanceolatum, a close relative of vertebrates

Bentele, Caterina, Krüger, Olaf, Tödtmann, Ulf, Oley, Mareke, Ragg, Hermann

Lancelets are considered to take a key position in the evolution of lineages leading to vertebrates. Herein, a serpin from the lancelet Branchiostoma lanceolatum, Bl-Spn1, was identified that...