Systems Biology Approaches to the Study of Apoptosis (2009)
Huber, Heinrich, Bullinger, Eric, Rehm, Markus
Today, we can avail of comprehensive information on the molecular mechanisms of apoptosis signaling that was gathered during decades of intense research. This chapter presents how mathematical...
Heinrich J. Huber, Markus Rehm, Martin Plchut, Heiko Düssmann, H. M. Prehn
to apoptosis
Antithrombin reduces shedding of the endothelial glycocalyx following ischaemia/reperfusion (2009)
Chappell, Daniel, Jacob, Matthias, Hofmann-Kiefer, Klaus, Rehm, Markus, Welsch, Ulrich, Conzen, Peter, ...
Aims Antithrombin is an important inhibitor of the coagulation system, additionally exerting specific anti-inflammatory effects on endothelial cells. Healthy vascular endothelium is coated by the...
Opioid-induced constipation in intensive care patients: relief in sight? (2008)
Chappell, Daniel, Rehm, Markus, Conzen, Peter
Abstract Constipation is the most common gastrointestinal complication associated with opioid therapy in chronic pain patients, and also frequently occurs in sedated intensive care unit patients....
Bruegger, Dirk, Rehm, Markus, Jacob, Matthias, Chappell, Daniel, Stoeckelhuber, Mechthild, Welsch, Ulrich, ...
Abstract Introduction Postischemic injury to the coronary vascular endothelium, in particular to the endothelial glycocalyx, may provoke fluid extravasation. Shedding of the glycocalyx is triggered...
BIOINFORMATICS APPLICATIONS NOTE doi:10.1093/bioinformatics/btl684 Systems biology (2008)
Heinrich J. Huber, Markus Rehm, Martin Plchut, Heiko Düssmann
APOPTO-CELL—a simulation tool and interactive database for analyzing cellular susceptibility to apoptosis
Jacob, Matthias, Chappell, Daniel, Conzen, Peter, Wilkes, Mahlon M, Becker, Bernhard F, Rehm, Markus
Abstract Background Small-volume resuscitation can rapidly correct hypovolemia. Hyperoncotic albumin solutions, long in clinical use, are suitable for small-volume resuscitation; however, their...
Causes of metabolic acidosis in canine hemorrhagic shock: role of unmeasured ions (2007)
Bruegger, Dirk, Kemming, Gregor I, Jacob, Matthias, Meisner, Franz G, Wojtczyk, Christoph J, Packert, Kristian B, ...
Abstract Introduction Metabolic acidosis during hemorrhagic shock is common and conventionally considered to be due to hyperlactatemia. There is increasing awareness, however, that other nonlactate,...
Huber, Heinrich J., Rehm, Markus, Plchut, Martin, Düssmann, Heiko, Prehn, Jochen H. M.
We have developed a web service that provides a comprehensive analysis of the susceptibility of cells to undergo apoptosis in response to an activation of the mitochondrial apoptotic pathway. Based...
Full Length Bid is sufficient to induce apoptosis of cultured rat hippocampal neurons (2007)
König, Hans-Georg, Rehm, Markus, Gudorf, Daniel, Krajewski, Stan, Gross, Atan, Ward, Manus W, ...
Abstract Background Bcl-2 homology domain (BH) 3-only proteins are pro-apoptotic proteins of the Bcl-2 family that couple stress signals to the mitochondrial cell death pathways. The BH3-only protein...
Jacob, Matthias, Bruegger, Dirk, Rehm, Markus, Stoeckelhuber, Mechthild, Welsch, Ulrich, Conzen, Peter, ...
Objective: To test the role of an oncotic pressure gradient across the endothelial glycocalyx with respect to extravasation of fluid and colloids and development of tissue edema in a whole organ...
Matthias Jacob, Peter Conzen, Udilo Finsterer, Er Krafft, Bernhard F, Markus Rehm, ...
doi:10.1152/japplphysiol.00740.2006 You might find this additional information useful... This article cites 47 articles, 15 of which you can access free at:
München, Univ., Diss., 1996.
Full Length Bid is sufficient to induce apoptosis of cultured rat hippocampal neurons
König, Hans-Georg, Rehm, Markus, Gudorf, Daniel, Krajewski, Stan, Gross, Atan, Ward, Manus W, ...
Rehm, Markus, Huber, Heinrich J, Dussmann, Heiko, Prehn, Jochen H M
Activation of effector caspases is a final step during apoptosis. Single-cell imaging studies have demonstrated that this process may occur as a rapid, all-or-none response, triggering a complete...
Causes of metabolic acidosis in canine hemorrhagic shock: role of unmeasured ions
Bruegger, Dirk, Kemming, Gregor I, Jacob, Matthias, Meisner, Franz G, Wojtczyk, Christoph J, Packert, Kristian B, ...
Real-time single cell analysis of Smac/DIABLO release during apoptosis
Rehm, Markus, Düßmann, Heiko, Prehn, Jochen H.M.
We examined the temporal and causal relationship between Smac/DIABLO release, cytochrome c (cyt-c) release, and caspase activation at the single cell level during apoptosis. Cells treated with the...
Jacob, Matthias, Chappell, Daniel, Conzen, Peter, Wilkes, Mahlon M, Becker, Bernhard F, Rehm, Markus
Bruegger, Dirk, Rehm, Markus, Jacob, Matthias, Chappell, Daniel, Stoeckelhuber, Mechthild, Welsch, Ulrich, ...
Köhler, Barbara, Anguissola, Sergio, Concannon, Caoimhin G., Rehm, Markus, Kögel, Donat, Prehn, Jochen H. M.
Opioid-induced constipation in intensive care patients: relief in sight?
Chappell, Daniel, Rehm, Markus, Conzen, Peter
Constipation is the most common gastrointestinal complication associated with opioid therapy in chronic pain patients, and also frequently occurs in sedated intensive care unit patients. Conventional...