Bmc Genomics, Jack Y Yang, Andrzej Niemierko, Mary Qu Yang, Youping Deng
Analyzing adjuvant radiotherapy suggests a non monotonic radio-sensitivity over tumor volumes
Guo-zheng Li, Hao-hua Meng, Mary Qu Yang, Youping Deng, Jack Y. Yang, Jack Y. Yang
Background: Since the high dimensionality of gene expression microarray data set hurts generalization performance of classifiers, feature selection has been widely used in the bioinformatics field,...
Guo-zheng Li, Hao-hua Meng, Wen-cong Lu, Jack Y. Yang, Mary Qu Yang, Mary Qu Yang
bagging and feature selection for activities prediction
Mary Qu Yang, Laura L. Elnitski
The last 50 years have marked a rapid expansion in our knowledge of the genetic material known as DNA. In 1953 Jim Watson and Francis Crick published a series of papers proposing the structure and...
Supervised learning-based tagSNP selection for genome-wide disease classifications (2008)
Liu, Qingzhong, Yang, Jack, Chen, Zhongxue, Yang, Mary Qu, Sung, Andrew H, Huang, Xudong
Abstract Background Comprehensive evaluation of common genetic variations through association of single nucleotide polymorphisms (SNPs) with complex human diseases on the genome-wide scale is an...
Yang, Jack Y, Yang, Mary Qu, Luo, Zuojie, Ma, Yan, Li, Jianling, Deng, Youping, ...
Abstract Background The prognosis for many cancers could be improved dramatically if they could be detected while still at the microscopic disease stage. It follows from a comprehensive statistical...
Prediction-based approaches to characterize bidirectional promoters in the mammalian genome (2008)
Yang, Mary Qu, Elnitski, Laura L
Abstract Background Machine learning approaches are emerging as a way to discriminate various classes of functional elements. Previous attempts to create Regulatory Potential (RP) scores to...
Habib, Tanwir, Zhang, Chaoyang, Yang, Jack Y, Yang, Mary Qu, Deng, Youping
Abstract Background Occurrence of protein in the cell is an important step in understanding its function. It is highly desirable to predict a protein's subcellular locations automatically from its...
A comparative study of different machine learning methods on microarray gene expression data (2008)
Pirooznia, Mehdi, Yang, Jack Y, Yang, Mary Qu, Deng, Youping
Abstract Background Several classification and feature selection methods have been studied for the identification of differentially expressed genes in microarray data. Classification methods such as...
Oldfield, Christopher J, Meng, Jingwei, Yang, Jack Y, Yang, Mary Qu, Uversky, Vladimir N, Dunker, A Keith
Abstract Background Proteins are involved in many interactions with other proteins leading to networks that regulate and control a wide variety of physiological processes. Some of these proteins,...
Promoting synergistic research and education in genomics and bioinformatics (2008)
Yang, Jack Y, Yang, Mary Qu, Zhu, Mengxia (Michelle), Arabnia, Hamid R, Deng, Youping
Abstract Bioinformatics and Genomics are closely related disciplines that hold great promises for the advancement of research and development in complex biomedical systems, as well as public health,...
Yang, Jack Y., Yang, Mary Qu, Arabnia, Hamid R., Deng, Youping
Supported by National Science Foundation (NSF), International Society of Intelligent Biological Medicine (ISIBM), International Journal of Computational Biology and Drug Design and International...
Research Predicting protein disorder by analyzing amino acid sequence (2008)
Bmc Genomics, Jack Y Yang, Mary Qu Yang
This is an open access article distributed under the terms of the Creative Commons Attribution License
Mary Qu Yang, Laura M Koehly, Laura L Elnitski
A "bidirectional gene pair" comprises two adjacent genes whose transcription start sites are neighboring, but oriented away from each other. The intervening regulatory region is called a...
Flexible nets: disorder and induced fit in the associations of p53 and 14-3-3 with their partners
Oldfield, Christopher J, Meng, Jingwei, Yang, Jack Y, Yang, Mary Qu, Uversky, Vladimir N, Dunker, A Keith
A comparative study of different machine learning methods on microarray gene expression data
Pirooznia, Mehdi, Yang, Jack Y, Yang, Mary Qu, Deng, Youping
Supervised learning-based tagSNP selection for genome-wide disease classifications
Liu, Qingzhong, Yang, Jack, Chen, Zhongxue, Yang, Mary Qu, Sung, Andrew H, Huang, Xudong
Investigation of transmembrane proteins using a computational approach
Yang, Jack Y, Yang, Mary Qu, Dunker, A Keith, Deng, Youping, Huang, Xudong
Dimension reduction with redundant gene elimination for tumor classification
Zeng, Xue-Qiang, Li, Guo-Zheng, Yang, Jack Y, Yang, Mary Qu, Wu, Geng-Feng
Asymmetric bagging and feature selection for activities prediction of drug molecules
Li, Guo-Zheng, Meng, Hao-Hua, Lu, Wen-Cong, Yang, Jack Y, Yang, Mary Qu
ILOOP – a web application for two-channel microarray interwoven loop design
Pirooznia, Mehdi, Gong, Ping, Yang, Jack Y, Yang, Mary Qu, Perkins, Edward J, Deng, Youping
Microarray technology is widely applied to address complex scientific questions. However, there remain fundamental issues on how to design experiments to ensure that the resulting data enables robust...
Selecting subsets of newly extracted features from PCA and PLS in microarray data analysis
Li, Guo-Zheng, Bu, Hua-Long, Yang, Mary Qu, Zeng, Xue-Qiang, Yang, Jack Y
Analyzing adjuvant radiotherapy suggests a non monotonic radio-sensitivity over tumor volumes
Yang, Jack Y, Niemierko, Andrzej, Yang, Mary Qu, Deng, Youping
Yang, Mary Qu, Athey, Brian D, Arabnia, Hamid R, Sung, Andrew H, Liu, Qingzhong, Yang, Jack Y, ...
The advent of high-throughput next generation sequencing technologies have fostered enormous potential applications of supercomputing techniques in genome sequencing, epi-genetics, metagenomics,...