Matthew J. Betzenhauser

ATP Modulation of Ca2+ Release by Type-2 and Type-3 Inositol (1, 4, 5)-Triphosphate Receptors: DIFFERING ATP SENSITIVITIES AND MOLECULAR DETERMINANTS OF ACTION*

Betzenhauser, Matthew J., Wagner, Larry E., Iwai, Miwako, Michikawa, Takayuki, Mikoshiba, Katsuhiko, Yule, David I.

ATP enhances Ca2+ release from inositol (1,4,5)-trisphosphate receptors (InsP3R). However, the three isoforms of InsP3R are reported to respond to ATP with differing sensitivities. Ca2+ release...

Visualizing form and function in organotypic slices of the adult mouse parotid gland

Warner, Jennifer D., Peters, Christian G., Saunders, Rudel, Won, Jong Hak, Betzenhauser, Matthew J., Gunning, William T., ...

An organotypic slice preparation of the adult mouse parotid salivary gland amenable to a variety of optical assessments of fluid and protein secretion dynamics is described. The semi-intact...

The Type 2 Inositol (1,4,5)-Trisphosphate (InsP3) Receptor Determines the Sensitivity of InsP3-induced Ca2+ Release to ATP in Pancreatic Acinar Cells*

Park, Hyung Seo, Betzenhauser, Matthew J., Won, Jong Hak, Chen, Ju, Yule, David I.

Calcium release through inositol (1,4,5)-trisphosphate receptors (InsP3R) is the primary signal driving digestive enzyme and fluid secretion from pancreatic acinar cells. The type 2 (InsP3R2) and...