Philippi, Nicole, Walter, Dorothee, Schlatter, Rebekka, Ferreira, Karine, Ederer, Michael, Sawodny, Oliver, ...
Abstract Background The decision pro- or contra apoptosis is complex, involves a number of different inputs, and is central for the homeostasis of an individual cell as well as for the maintenance...
Michael Ederer, Thomas Sauter, Eric Bullinger, Ernst-dieter Gilles, Frank Allgöwer, Michael Ederer, ...
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Reduced modeling of signal transduction – a modular approach (2007)
Koschorreck, Markus, Conzelmann, Holger, Ebert, Sybille, Ederer, Michael, Gilles, Ernst
Abstract Background Combinatorial complexity is a challenging problem in detailed and mechanistic mathematical modeling of signal transduction. This subject has been discussed intensively and a lot...
Reduced modeling of signal transduction – a modular approach (2007)
Bmc Bioinformatics, Markus Koschorreck, Holger Conzelmann, Sybille Ebert, Michael Ederer, Ernst Dieter Gilles
This is an Open Access article distributed under the terms of the Creative Commons Attribution License
An approach for dividing models of biological reaction networks into functional units (2003)
Ederer, Michael, Sauter, Thomas, Bullinger, Eric, Gilles, E. D., Allgöwer, Frank
Biological reaction networks consist of many substances and reactions between them. Like many other biological systems, they have a modular structure. Therefore, a division of a biological reaction...
Reduced modeling of signal transduction – a modular approach
Koschorreck, Markus, Conzelmann, Holger, Ebert, Sybille, Ederer, Michael, Gilles, Ernst Dieter
Thermodynamically Feasible Kinetic Models of Reaction Networks
Ederer, Michael, Gilles, Ernst Dieter
The dynamics of biological reaction networks are strongly constrained by thermodynamics. An holistic understanding of their behavior and regulation requires mathematical models that observe these...