Themenheft 45 "Ausgaben und Finanzierung des Gesundheitswesens" (2009)
In der Gesundheitsausgabenrechnung wird der gesamte volkswirtschaftliche Ressourcenverbrauch ermittelt, der jährlich für den Erhalt und die Wiederherstellung der Gesundheit aufgewendet wird....
OPINION Nutrigenomics: goals and strategies (2009)
Nutrigenomics is the application of highthroughput genomics tools in nutrition research. Applied wisely, it will promote an increased understanding of how nutrition influences metabolic pathways and...
Enhanced Hypoxia Susceptibility in Hippocampal Slices From a Mouse Model of Rett Syndrome (2009)
Reuter, Julia, Hildebrandt, Belinda, Haegele, Sonja, Katschinski, Doerthe, ...
Fischer M, Reuter J, Gerich FJ, Hildebrandt B, Hagele S, Katschinski D, Muller M. Enhanced hypoxia susceptibility in hippocampal slices from a mouse model of Rett syndrome. J Neurophysiol 101:...
Zum Isomorphieproblem von Darstellungsringen (2009)
Die Darstellungstheorie endlicher Gruppen beschäftigt sich mit der Klassifikation der Ähnlichkeitsklassen von Darstellungen einer endlichen Gruppe G über einem Körper K. Äquivalent hierzu ist...
Erythropoietin enhances hippocampal long-term potentiation and memory (2008)
Adamcio, Bartosz, Sargin, Derya, Stradomska, Alicja, Medrihan, Lucian, Gertler, Christoph, Theis, Fabian, ...
Abstract Background Erythropoietin (EPO) improves cognition of human subjects in the clinical setting by as yet unknown mechanisms. We developed a mouse model of robust cognitive improvement by EPO...
Transcriptional regulation of nutrient metabolism by PPARα, α, α, γ γ (2008)
David Patsouris, Promotor Prof, Dr. Michael Müller, Hoogleraar Voeding, Prof. Dr. Martien Groenen, ...
Dit onderzoek is uitgevoerd binnen de onderzoeksschool VLAG Transcriptional regulation of nutrient metabolism by PPARα, α, α, γ γ and LXRα
Müller, Michael, Morawietz, Lars, Hasart, Olaf, Strube, Patrick, Perka, Carsten, Tohtz, Stephan
Abstract Background The correct diagnosis of a prosthetic joint infection (PJI) is crucial for adequate surgical treatment. The detection may be a challenge since presentation and preoperative tests...
Bouwens, Mark, Afman, Lydia A, Müller, Michael
Abstract Background Peripheral blood mononuclear cells (PBMCs) are relatively easily obtainable cells in humans. Gene expression profiles of PBMCs have been shown to reflect the pathological and...
PPARalpha-mediated effects of dietary lipids on intestinal barrier gene expression (2008)
Bünger, Meike, De Groot, Philip J, Bosch-Vermeulen, Hanneke, Hooiveld, Guido JEJ, Müller, Michael
Abstract Background The selective absorption of nutrients and other food constituents in the small intestine is mediated by a group of transport proteins and metabolic enzymes, often collectively...
De Wit, Nicole JW, Bosch-Vermeulen, Hanneke, De Groot, Philip J, Hooiveld, Guido JEJ, Bromhaar, Mechteld, Jansen, Jenny, ...
Abstract Background Obesity and insulin resistance are two major risk factors underlying the metabolic syndrome. The development of these metabolic disorders is frequently studied, but mainly in...
Müller, Michael, Disch, Aleaxander C, Zabel, Nicole, Haas, Norbert P, Schaser, Klaus D
Abstract Background The severity of associated soft tissue trauma in complex injuries of the extremities guides fracture treatment and decisively determines patient's prognosis. Trauma-induced...
Funke, Frank, Müller, Michael, Dutschmann, Mathias
Recent studies showed that respiratory rhythm generation depends on oscillators located in the pre-Bötzinger complex (pre-BötC) and the parafacial respiratory group (pFRG). To study inhibitory...
Erythropoietin enhances hippocampal long-term potentiation and memory (2008)
Adamcio, Bartosz, Sargin, Derya, Stradomska, Alicja, Medrihan, Lucian, Gertler, Christoph, Theis, Fabian, ...
Herschel open time key programme: TNOs are cool: a survey of the transneptunian region (2008)
Müller, Thomas G., Lellouch, Emmanuel, Böhnhardt, Hermann, Stansberry, John, Barucci, Antonella, Crovisier, Jacques, ...
Michael Müller, Klaus Ballanyi, J Neurophysiol, T. Miki, ...
You might find this additional information useful... This article cites 50 articles, 14 of which you can access free at:
Retrieval and Analysis of Software Systems from SCM Repositories (2007)
One source of input data for software evolution research is data stored inside a software configuration management repository. The data includes different versions of a software system’s source...
Retrieval and Analysis of Software Systems from SCM Repositories (2007)
One source of input data for software evolution research is data stored inside a software configuration management repository. The data includes different versions of a software system’s source...
Van Den Bosch, Heleen M, Bünger, Meike, De Groot, Philip J, Van Der Meijde, Jolanda, Hooiveld, Guido JEJ, Müller, Michael
Abstract Background Fasting has dramatic effects on small intestinal transport function. However, little is known on expression of intestinal transport and phase I/II metabolism genes during fasting...
PPARs, Obesity, and Inflammation (2007)
Rinke Stienstra, Caroline Duval, Michael Müller, Sander Kersten
The worldwide prevalence of obesity and related metabolic disorders is rising rapidly, increasing the burden on our healthcare system. Obesity is often accompanied by excess fat storage in tissues...
Maryam Rakhshandehroo, Linda M. Sanderson, Merja Matilainen, Rinke Stienstra, Carsten Carlberg, ...
PPARα is a ligand-activated transcription factor involved in the regulation of nutrient metabolism and inflammation. Although much is already known about the function of PPARα in hepatic lipid...
Photometry of Karin Family Asteroids (2006)
Hahn, Gerhard, Mottola, Stefano, Sen, Asoke K., Harris, Alan W., Kührt, Ekkehard, Müller, Michael
We have performed photometric observations in the V-band of two asteroids belonging to the Karin asteroid family, (11728) Einer and (93690) 2000 VE21 , using the 2-m Himalayan Chandra Telescope,...
Neusch, Clemens, Papadopoulos, Nestoras, Müller, Michael, Maletzki, Iris, Winter, Stefan M., Hirrlinger, Johannes, ...
Thermodynamic characterization of an engineered tetracycline-binding riboswitch (2006)
Müller, Michael, Weigand, Julia E., Weichenrieder, Oliver, Suess, Beatrix
Riboswitches reflect a novel concept in gene regulation that is particularly suited for technological adaptation. Therefore, we characterized thermodynamically the ligand binding properties of a...
Erholung kognitiver und psychomotorischer Funktionen nach balancierter Anästhesie (2005)
In der vorliegenden offenen, randomisierten und prospektiven Studie wurde die Erholung der kognitiven und psycho- motorischen Leistungsfähigkeit nach einer balancierten Anästhesie mit Isofluran und...
Erholung kognitiver und psychomotorischer Funktionen nach balancierter Anästhesie (2005)
In der vorliegenden offenen, randomisierten und prospektiven Studie wurde die Erholung der kognitiven und psycho- motorischen Leistungsfähigkeit nach einer balancierten Anästhesie mit Isofluran und...
Wüstefeld, Torsten, Assmus, Ulrike, Rose-John, Stefan, Müller, Michael, ...
Increasing evidence demonstrates that IL-6 has a protective role during liver injury. IL-6 activates intracellular pathways via the gp130 receptor. In order to identify IL-6-gp130 pathways involved...
Die Diplomarbeit mit dem Thema die Entstehung, die Umsetzung und dieAuswirkungen der EG-Tabak-Produktrichtlinie ist in drei Teile gegliedert. In Teil Einsder Arbeit wird die Entstehung der...
Development and Design of a Centrifugal Compressor Volute (2005)
The volute is one of the key components of a centrifugal compressor. The design of the volute not only impacts the compressor efficiency but also influences the operating range. The detailed flow...
Schilling, Oliver, Langbein, Ines, Müller, Michael, Schmalisch, Matthias H., Stülke, Jörg
The Gram‐positive soil bacterium Bacillus subtilis transports glucose by the phosphotransferase system. The genes for this system are encoded in the ptsGHI operon. The expression of this operon...
...
Constraining cometary ejection models from meteor storm observations (2001)
Müller, Michael, Green, Simon F., McBride, Neil
Modelling and observations of the Leonids have shown that maxima in the meteor storm activity can be identified as due to particles released from the comet during certain perihelion passages. If the...
Interpretation. Franz Kafka: Die Verwandlung (2001)
Der AutorMichael Müller, geboren 1950. Studium der Anglistik und Germanistik in Köln. Dr. phil. Mitarbeiter der Kritischen Kafka-Ausgabe.Publikationen: Franz Kafka: Relazioni. 1988 - (Mithrsg.)...
Interpretation. Hermann Hesse: Unterm Rad (2001)
Der AutorMichael Müller, geboren 1950. Studium der Anglistik und Germanistik in Köln. Dr. phil. Mitarbeiter der Kritischen Kafka-Ausgabe.Publikationen: Franz Kafka: Relazioni. 1988 - (Mithrsg.)...
Intelligent Data Mining for Medical Quality Management (2000)
Wolf Stühlinger, Oliver Hogl, Herbert Stoyan, Michael Müller
. In the healthcare sector cost pressure is growing, quality demands are rising and the competitive situation amongst suppliers is mounting. These developments confront hospitals more than ever with...
...
Prediction of the In-Situ Dust Measurements of the Stardust Mission to Comet 81P/Wild 2 (1999)
Landgraf, Markus, Müller, Michael, Grün, Eberhard
We predict the amount of cometary, interplanetary, and interstellar cosmic dust that is to be measured by the Cometary and Interstellar Dust Analyzer (CIDA) and the aerogel collector on-board the...
Convex Hulls in Higher-dimensional Space (1998)
Michael Müller, Joachim Ziegler, Kurt Mehlhorn, Michael Seel
We define and implement the data type chull . It maintains convex hulls in arbitrary dimensions and supports insertions of points and membership queries. The interior of the hull and the boundary of...
Arithmetic of modular curves and applications (1998)
The aim of this article is to describe a computational approach to the study of the arithmetic of modular curves X 0 (N) and to give applications of these computations.
The Tate Pairing and the Discrete Logarithm Applied to Elliptic Curve Cryptosystems (1998)
Gerhard Frey, Michael Müller, Hans-Georg Rück
to the addition in J. 3. Given a cyclic subgroup Cm of order m in Jm (F q ) then the probability to find a point P 0 in J(F q ) with fOE m (P; P 0 ); P 2 Cm g = ¯m (F q ) is positive ( depending on...
A computational basis for higher-dimensional computational geometry and applications (1998)
Mehlhorn, Kurt, Müller, Michael, Näher, Stefan, Schirra, Stefan, Seel, Michael, Uhrig, Christian, ...
A Computational Basis for Higher-dimensional Computational Geometry and Applications (1997)
Mehlhorn, Kurt, Müller, Michael, Näher, Stefan, Schirra, Stefan, Seel, Michael, Uhrig, Christian, ...
Michael Müller, Joachim Ziegler, Kurt Mehlhorn
We define and implement the data type chull. It maintains convex hulls in arbitrary dimensions and supports insertions of points and membership queries. The interior of the hull and the boundary of...
Higher-dimensional Convex Hulls and Delaunay Triangulations Specification and Implementation (1996)
Kurt Mehlhorn, Michael Müller, Stefan Näher, Joachim Ziegler
Introduction We discuss the specification and implementation of the data types convex hull and Delaunay triangulation for higher-dimensional space. We aimed for ffl rich functionality and ease of use...
An Implementation of a Convex Hull Algorithm Version 1.0 (1994)
Michael Müller, Joachim Ziegler
We give an implementation of an incremental construction algorithm for convex hulls in IR d using Literate Programming and LEDA in C++. We treat convex hulls in arbitrary dimensions without any...
La villa como arquitectura del poder / Reinhard Bentmann y Michel Müller (1975)
Bentmann, Reinhard, Müller, Michael
Traducción de: Die villa als herrschaftsarchiektur
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Van Veen, Hendrik W., Margolles, Abelardo, Müller, Michael, Higgins, Christopher F., Konings, Wil N.
The bacterial LmrA protein and the mammalian multidrug resistance P-glycoprotein are closely related ATP-binding cassette (ABC) transporters that confer multidrug resistance on cells by mediating the...
Schilling, Oliver, Langbein, Ines, Müller, Michael, Schmalisch, Matthias H., Stülke, Jörg
The Gram-positive soil bacterium Bacillus subtilis transports glucose by the phosphotransferase system. The genes for this system are encoded in the ptsGHI operon. The expression of this operon is...
PPARα governs glycerol metabolism
Patsouris, David, Mandard, Stéphane, Voshol, Peter J., Escher, Pascal, Tan, Nguan Soon, Havekes, Louis M., ...
Glycerol, a product of adipose tissue lipolysis, is an important substrate for hepatic glucose synthesis. However, little is known about the regulation of hepatic glycerol metabolism. Here we show...
Klein, Christian, Wüstefeld, Torsten, Assmus, Ulrike, Roskams, Tania, Rose-John, Stefan, Müller, Michael, ...
Increasing evidence demonstrates that IL-6 has a protective role during liver injury. IL-6 activates intracellular pathways via the gp130 receptor. In order to identify IL-6–gp130 pathways involved...
The G0/G1 switch gene 2 is a novel PPAR target gene
Zandbergen, Fokko, Mandard, Stéphane, Escher, Pascal, Tan, Nguan Soon, Patsouris, David, Jatkoe, Tim, ...
PPARs (peroxisome-proliferator-activated receptors) α, β/δ and γ are a group of transcription factors that are involved in numerous processes, including lipid metabolism and adipogenesis. By...
The Notch Signaling Pathway Is Related to Neurovascular Progression of Pancreatic Cancer
Büchler, Peter, Gazdhar, Amiq, Schubert, Mario, Giese, Nathalia, Reber, Howard A., Hines, Oscar J., ...
The Notch signaling pathway is well known as a neuronal pathway. This study shows that the Notch pathway plays a pivotal role in angiogenesis in pancreatic cancer. Jagged-1, a Notch ligand, and...
Thermodynamic characterization of an engineered tetracycline-binding riboswitch
Müller, Michael, Weigand, Julia E., Weichenrieder, Oliver, Suess, Beatrix
Riboswitches reflect a novel concept in gene regulation that is particularly suited for technological adaptation. Therefore, we characterized thermodynamically the ligand binding properties of a...
Van Veen, Hendrik W., Margolles, Abelardo, Müller, Michael, Higgins, Christopher F., Konings, Wil N.
The bacterial LmrA protein and the mammalian multidrug resistance P-glycoprotein are closely related ATP-binding cassette (ABC) transporters that confer multidrug resistance on cells by mediating the...
Schilling, Oliver, Langbein, Ines, Müller, Michael, Schmalisch, Matthias H., Stülke, Jörg
The Gram-positive soil bacterium Bacillus subtilis transports glucose by the phosphotransferase system. The genes for this system are encoded in the ptsGHI operon. The expression of this operon is...
PPARα governs glycerol metabolism
Patsouris, David, Mandard, Stéphane, Voshol, Peter J., Escher, Pascal, Tan, Nguan Soon, Havekes, Louis M., ...
Glycerol, a product of adipose tissue lipolysis, is an important substrate for hepatic glucose synthesis. However, little is known about the regulation of hepatic glycerol metabolism. Here we show...
Klein, Christian, Wüstefeld, Torsten, Assmus, Ulrike, Roskams, Tania, Rose-John, Stefan, Müller, Michael, ...
Increasing evidence demonstrates that IL-6 has a protective role during liver injury. IL-6 activates intracellular pathways via the gp130 receptor. In order to identify IL-6–gp130 pathways involved...
The G0/G1 switch gene 2 is a novel PPAR target gene
Zandbergen, Fokko, Mandard, Stéphane, Escher, Pascal, Tan, Nguan Soon, Patsouris, David, Jatkoe, Tim, ...
PPARs (peroxisome-proliferator-activated receptors) α, β/δ and γ are a group of transcription factors that are involved in numerous processes, including lipid metabolism and adipogenesis. By...
The Notch Signaling Pathway Is Related to Neurovascular Progression of Pancreatic Cancer
Büchler, Peter, Gazdhar, Amiq, Schubert, Mario, Giese, Nathalia, Reber, Howard A., Hines, Oscar J., ...
The Notch signaling pathway is well known as a neuronal pathway. This study shows that the Notch pathway plays a pivotal role in angiogenesis in pancreatic cancer. Jagged-1, a Notch ligand, and...
Thermodynamic characterization of an engineered tetracycline-binding riboswitch
Müller, Michael, Weigand, Julia E., Weichenrieder, Oliver, Suess, Beatrix
Riboswitches reflect a novel concept in gene regulation that is particularly suited for technological adaptation. Therefore, we characterized thermodynamically the ligand binding properties of a...
PPARs, Obesity, and Inflammation
Stienstra, Rinke, Duval, Caroline, Müller, Michael, Kersten, Sander
The worldwide prevalence of obesity and related metabolic disorders is rising rapidly, increasing the burden on our healthcare system. Obesity is often accompanied by excess fat storage in tissues...
Identification of Novel Benzoylformate Decarboxylases by Growth Selection▿†
Henning, Helge, Leggewie, Christian, Pohl, Martina, Müller, Michael, Eggert, Thorsten, Jaeger, Karl-Erich
A growth selection system was established using Pseudomonas putida, which can grow on benzaldehyde as the sole carbon source. These bacteria presumably metabolize benzaldehyde via the β-ketoadipate...
Van Den Bosch, Heleen M, Bünger, Meike, De Groot, Philip J, Van Der Meijde, Jolanda, Hooiveld, Guido JEJ, Müller, Michael
Renes, Johan, Nienhuis, Edith F, Jansen, Peter L M, Müller, Michael
The present study was performed to investigate the ability of the multidrug resistance protein (MRP1) to transport different cationic substrates in comparison with MDR1-P-glycoprotein (MDR1)....
Vellenga, Edo, Tuyt, Leonore, Wierenga, Bart-Jan, Müller, Michael, Dokter, Wim
The intracellular transport of leukotriene C4 (LTC4) in hematopoietic cells such as human monocytes is controlled by an ATP dependent carrier encoded by the multidrug resistance protein1 (MRP1) gene...
Heegsma, Janette, Montfoort, Jessica E Van, Jansen, Peter L M, Meijer, Dirk K F, Müller, Michael
The present study was performed to evaluate and compare the ability of human MDR1-, and rat Mdr1b- and Mdr2-P-glycoproteins to transport hydrophilic monoquaternary drugs. Transport studies were...
Erb, Tobias J., Berg, Ivan A., Brecht, Volker, Müller, Michael, Fuchs, Georg, Alber, Birgit E.
Fifty years ago, Kornberg and Krebs established the glyoxylate cycle as the pathway for the synthesis of cell constituents from C2-units. However, since then, many bacteria have been described that...
Rakhshandehroo, Maryam, Sanderson, Linda M., Matilainen, Merja, Stienstra, Rinke, Carlberg, Carsten, De Groot, Philip J., ...
PPARα is a ligand-activated transcription factor involved in the regulation of nutrient metabolism and inflammation. Although much is already known about the function of PPARα in hepatic lipid...
Effect of Synthetic Dietary Triglycerides: A Novel Research Paradigm for Nutrigenomics
Sanderson, Linda M., De Groot, Philip J., Koppen, Arjen, Kalkhoven, Eric, Müller, Michael, ...
Molecular determinants of Ca2+-dependent K+ channel function in rat dorsal vagal neurones
Pedarzani, Paola, Kulik, Anna, Müller, Michael, Ballanyi, Klaus, Stocker, Martin
Using in situ hybridisation histochemistry in combination with patch-clamp recordings and specific pharmacological tools, the molecular nature of the channels underlying Ca2+-dependent K+ currents...
Die ökologische Situation in Kasachstan
Den Umweltproblemen der Staaten Ost- und Mitteleuropas sowie der Nachfolgestaaten der Sowjetunion muss innerhalb der Transformationsforschung angesichts des Ausmaßes der dortigen Umweltbelastung...
De Wit, Nicole JW, Bosch-Vermeulen, Hanneke, De Groot, Philip J, Hooiveld, Guido JEJ, Bromhaar, Mechteld M Grootte, Jansen, Jenny, ...
PPARalpha-mediated effects of dietary lipids on intestinal barrier gene expression
Bünger, Meike, De Groot, Philip J, Bosch-Vermeulen, Hanneke, Hooiveld, Guido JEJ, Müller, Michael
Mesaconyl-Coenzyme A Hydratase, a New Enzyme of Two Central Carbon Metabolic Pathways in Bacteria▿
Zarzycki, Jan, Schlichting, Ansgar, Strychalsky, Nina, Müller, Michael, Alber, Birgit E., Fuchs, Georg
The coenzyme A (CoA)-activated C5-dicarboxylic acids mesaconyl-CoA and β-methylmalyl-CoA play roles in two as yet not completely resolved central carbon metabolic pathways in bacteria. First, these...
The challenges for molecular nutrition research 2: quantification of the nutritional phenotype
Van Ommen, Ben, Keijer, Jaap, Kleemann, Robert, Elliott, Ruan, Drevon, Christian A., McArdle, Harry, ...
In quantifying the beneficial effect of dietary interventions in healthy subjects, nutrition research meets a number of new challenges. Inter individual variation in biomarker values often is larger...
Erythropoietin enhances hippocampal long-term potentiation and memory
Adamcio, Bartosz, Sargin, Derya, Stradomska, Alicja, Medrihan, Lucian, Gertler, Christoph, Theis, Fabian, ...
Baccini, Michela, Bachmaier, Eva-Maria, Biggeri, Annibale, Boekschoten, Mark V., Bouwman, Freek G., Brennan, Lorraine, ...
Murphy, Eileen F., Hooiveld, Guido J., Müller, Michael, Calogero, Raffaelle A., Cashman, Kevin D.
We conducted an in-depth investigation of the effects of conjugated linoleic acid (CLA) on the expression of key metabolic genes and genes of known importance in intestinal lipid metabolism using the...
H2O2-mediated modulation of cytosolic signaling and organelle function in rat hippocampus
Gerich, Florian J., Funke, Frank, Hildebrandt, Belinda, Faßhauer, Martin, Müller, Michael
Reactive oxygen species (ROS) released from (dys-)functioning mitochondria contribute to normal and pathophysiological cellular signaling by modulating cytosolic redox state and redox-sensitive...