Nygaard, Sanne, Jacobsen, Anders, Lindow, Morten, Eriksen, Jens, Balslev, Eva, Flyger, Henrik, ...
Abstract Background MiRNAs play important roles in cellular control and in various disease states such as cancers, where they may serve as markers or possibly even therapeutics. Identifying the whole...
Principles and Limitations of Computational MicroRNA Gene (2008)
Target Finding, Morten Lindow, Jan Gorodkin
In 2001 there were four PubMed entries matching the word ‘‘microRNA’ ’ (miRNA). Interestingly, this number has now far exceeded 1300 and is still rapidly increasing. This more than anything...
Experimental identification of microRNA-140 targets by silencing and overexpressing miR-140 (2008)
Nicolas, Francisco Esteban, Pais, Helio, Schwach, Frank, Lindow, Morten, Kauppinen, Sakari, Moulton, Vincent, ...
MicroRNAs (miRNAs) are short noncoding RNA molecules regulating the expression of mRNAs. Target identification of miRNAs is computationally difficult due to the relatively low homology between miRNAs...
Elmén, Joacim, Lindow, Morten, Silahtaroglu, Asli, Bak, Mads, Christensen, Mette, Lind-Thomsen, Allan, ...
MicroRNA-122 (miR-122) is an abundant liver-specific miRNA, implicated in fatty acid and cholesterol metabolism as well as hepatitis C viral replication. Here, we report that a systemically...
Intragenomic Matching Reveals a Huge Potential for miRNA-Mediated Regulation in Plants (2007)
Morten Lindow, Anders Jacobsen, Sanne Nygaard, Yuan Mang, Anders Krogh
microRNAs (miRNAs) are important post-transcriptional regulators, but the extent of this regulation is uncertain, both with regard to the number of miRNA genes and their targets. Using an algorithm...
Computational evidence for hundreds of non-conserved plant microRNAs (2005)
Abstract Background MicroRNAs (miRNA) are small (20–25 nt) non-coding RNA molecules that regulate gene expression through interaction with mRNA in plants and metazoans. A few hundred miRNAs are...
The Virus-Encoded Chemokine vMIP-II Inhibits Virus-Induced Tc1-Driven Inflammation
Lindow, Morten, Nansen, Anneline, Bartholdy, Christina, Stryhn, Annette, Hansen, Nils J. V., Boesen, Thomas P., ...
The human herpesvirus 8-encoded protein vMIP-II is a potent in vitro antagonist of many chemokine receptors believed to be associated with attraction of T cells with a type 1 cytokine profile. For...
The Virus-Encoded Chemokine vMIP-II Inhibits Virus-Induced Tc1-Driven Inflammation
Lindow, Morten, Nansen, Anneline, Bartholdy, Christina, Stryhn, Annette, Hansen, Nils J. V., Boesen, Thomas P., ...
The human herpesvirus 8-encoded protein vMIP-II is a potent in vitro antagonist of many chemokine receptors believed to be associated with attraction of T cells with a type 1 cytokine profile. For...
Brain Expressed microRNAs Implicated in Schizophrenia Etiology
Hansen, Thomas, Olsen, Line, Lindow, Morten, Jakobsen, Klaus D., Ullum, Henrik, Jonsson, Erik, ...
Intragenomic Matching Reveals a Huge Potential for miRNA-Mediated Regulation in Plants
Lindow, Morten, Jacobsen, Anders, Nygaard, Sanne, Mang, Yuan, Krogh, Anders
microRNAs (miRNAs) are important post-transcriptional regulators, but the extent of this regulation is uncertain, both with regard to the number of miRNA genes and their targets. Using an algorithm...
Elmén, Joacim, Lindow, Morten, Silahtaroglu, Asli, Bak, Mads, Christensen, Mette, Lind-Thomsen, Allan, ...
MicroRNA-122 (miR-122) is an abundant liver-specific miRNA, implicated in fatty acid and cholesterol metabolism as well as hepatitis C viral replication. Here, we report that a systemically...
Experimental identification of microRNA-140 targets by silencing and overexpressing miR-140
Nicolas, Francisco Esteban, Pais, Helio, Schwach, Frank, Lindow, Morten, Kauppinen, Sakari, Moulton, Vincent, ...
MicroRNAs (miRNAs) are short noncoding RNA molecules regulating the expression of mRNAs. Target identification of miRNAs is computationally difficult due to the relatively low homology between miRNAs...