Nelly Camargo

Plasmodium liver stage developmental arrest by depletion of a protein at the parasite–host interface

Mueller, Ann-Kristin, Camargo, Nelly, Kaiser, Karine, Andorfer, Cathy, Frevert, Ute, Matuschewski, Kai, ...

Plasmodium parasites of mammals, including the species that cause malaria in humans, infect the liver first and develop there into clinically silent liver stages. Liver stages grow and ultimately...

Transformation of Sporozoites into Early Exoerythrocytic Malaria Parasites Does Not Require Host Cells

Kaiser, Karine, Camargo, Nelly, Kappe, Stefan H.I.

Malaria parasite species that infect mammals, including humans, must first take up residence in hepatic host cells as exoerythrocytic forms (EEF) before initiating infection of red blood cells that...

A combined transcriptome and proteome survey of malaria parasite liver stages

Tarun, Alice S., Peng, Xinxia, Dumpit, Ronald F., Ogata, Yuko, Silva-Rivera, Hilda, Camargo, Nelly, ...

For 50 years since their discovery, the malaria parasite liver stages (LS) have been difficult to analyze, impeding their utilization as a critical target for antiinfection vaccines and drugs. We...

Targeted deletion of SAP1 abolishes the expression of infectivity factors necessary for successful malaria parasite liver infection

Aly, Ahmed S I, Mikolajczak, Sebastian A, Rivera, Hilda Silva, Camargo, Nelly, Jacobs-Lorena, Vanessa, Labaied, Mehdi, ...

Malaria parasite sporozoites prepare for transmission to a mammalian host by upregulation of UIS (Upregulated in Infectious Sporozoites) genes. A number of UIS gene products are essential for the...

Distinct Malaria Parasite Sporozoites Reveal Transcriptional Changes That Cause Differential Tissue Infection Competence in the Mosquito Vector and Mammalian Host▿

Mikolajczak, Sebastian A., Silva-Rivera, Hilda, Peng, Xinxia, Tarun, Alice S., Camargo, Nelly, Jacobs-Lorena, Vanessa, ...

The malaria parasite sporozoite transmission stage develops and differentiates within parasite oocysts on the Anopheles mosquito midgut. Successful inoculation of the parasite into a mammalian host...

Type II fatty acid synthesis is essential only for malaria parasite late liver stage development

Vaughan, Ashley M, O'Neill, Matthew T, Tarun, Alice S, Camargo, Nelly, Phuong, Thuan M, Aly, Ahmed S I, ...

Intracellular malaria parasites require lipids for growth and replication. They possess a prokaryotic type II fatty acid synthesis (FAS II) pathway that localizes to the apicoplast plastid organelle...