P. Rümmele

Quantitative gene expression analysis of fractalkine using laser microdissection in biopsies from kidney allografts with acute rejection (2004)

Pietrzyk, M. C., Banas, B., Wolf, K., Rümmele, P., Woenckhaus, M., Hoffmann, U., ...

Percutaneous biopsy of the kidney remains the gold standard to establish a diagnosis in renal diseases. Only semiquantitative assessments of gene expression on biopsies have been possible so far. We...

Alterations in p53 predict response to preoperative high dose chemotherapy in patients with gastric cancer

Bataille, F, Rümmele, P, Dietmaier, W, Gaag, D, Klebl, F, Reichle, A, ...

Aims: To evaluate the usefulness of molecular markers in predicting histopathological and clinical response to preoperative high dose chemotherapy (HDCT) and survival of patients with advanced...

Alterations in p53 predict response to preoperative high dose chemotherapy in patients with gastric cancer

Bataille, F, Rümmele, P, Dietmaier, W, Gaag, D, Klebl, F, Reichle, A, ...

Aims: To evaluate the usefulness of molecular markers in predicting histopathological and clinical response to preoperative high dose chemotherapy (HDCT) and survival of patients with advanced...

Fluorescence endoscopy for the detection of low and high grade dysplasia in ulcerative colitis using systemic or local 5-aminolaevulinic acid sensitisation

Messmann, H, Endlicher, E, Freunek, G, Rümmele, P, Schölmerich, J, Knüchel, R

Background and aims: Longstanding ulcerative colitis (UC), especially in the presence of epithelial dysplasia, is associated with an increased risk of developing cancer. As dysplasia is not visible...

Analysis of intestinal haem-oxygenase-1 (HO-1) in clinical and experimental colitis

Paul, G, Bataille, F, Obermeier, F, Bock, J, Klebl, F, Strauch, U, ...

Haem-oxygenase-1 (HO-1) has been shown to exert anti-inflammatory, anti-apoptotic and anti-proliferative effects. We investigated HO-1 expression in patients with inflammatory bowel disease (IBD) and...

Morphological characterisation of Crohn’s disease fistulae

Bataille, F, Klebl, F, Rümmele, P, Schroeder, J, Farkas, S, Wild, P-J, ...

Background: Fistulae are a common complication in up to 35% of all patients with Crohn’s disease. Their therapy is difficult and frequently unsatisfactory. To date, no histological comparison of...

Protoporphyrin IX distribution following local application of 5-aminolevulinic acid and its esterified derivatives in the tissue layers of the normal rat colon

Endlicher, E, Rümmele, P, Hausmann, F, Krieg, R, Knüchel, R, Rath, H C, ...

Photodynamic diagnosis and especially therapy after sensitization with 5-aminolevulinic acid (ALA) is hampered by limitations of uptake and distribution of ALA due to its hydrophilic nature. Chemical...