Paul Van Cauwenberge

Enhanced release of IgE-dependent early phase mediators from nasal polyp tissue (2009)

Patou, Joke, Holtappels, Gabriele, Affleck, Karen, Gevaert, Philippe, Perez-Novo, Claudina, Van Cauwenberge, Paul, ...

Abstract Background The mast cell is a crucial effector cell in allergic rhinitis and other inflammatory diseases. During the acute allergic reaction preformed mediators such as histamine, but also...

Differential expression of the interleukin 5 receptor alpha isoforms in blood and tissue eosinophils of nasal polyp patients (2009)

Gevaert, Philippe, Hellman, C., Lundblad, L., Lundahl, J., Holtappels, Gabriële, Van Cauwenberge, Paul, ...

Given the key role of interleukin-5 (IL-5) in eosinophil function, we investigated the regulated expression of the membrane-anchored (TM-IL-5R alpha) isoform, or a secreted (SOL IL-5R alpha) isoform,...

Chronic rhinosinusitis with and without nasal polyps: what is the difference? (2009)

Huvenne, Wouter, Van Bruaene, Nicholas, Zhang, Nan, VAN ZELE, THIBAUT, Patou, Joke, Gevaert, Philippe, ...

Chronic rhinosinusitis is a heterogeneous group of chronic sinus diseases that may consist of clearly different disease entities. Further investigation of the pathomechanisms of chronic...

Perturbation Measures of Voice: A Comparative Study between Multi-Dimensional Voice Program and Praat (2009)

Maryn, Youri, Corthals, Paul, De Bodt, Marc, Van Cauwenberge, Paul, Deliyski, Dimitar

Background/Aims: Frequency and amplitude perturbations are inherent in voice acoustic signals. The assessment of voice perturbation is influenced by several factors, including the type of recording...

Acoustic measurement of overall voice quality: A meta-analysis (2009)

Maryn, Youri, Roy, Nelson, De Bodt, Marc, Van Cauwenberge, Paul, Corthals, Paul

Over the past several decades, many acoustic markers have been proposed to be sensitive to and measure overall voice quality. This meta-analysis presents a retrospective appraisal of scientific...

Toward Improved Ecological Validity in the Acoustic Measurement of Overall Voice Quality: Combining Continuous Speech and Sustained Vowels (2009)

Maryn, Youri, Corthals, Paul, Van Cauwenberge, Paul, Roy, Nelson, De Bodt, Marc

To improve ecological validity, perceptual and instrumental assessment of disordered voice, including overall voice quality, should ideally sample both sustained vowels and continuous speech. This...

Staphylococcus aureus enterotoxin B regulates prostaglandin E-2 synthesis, growth, and migration in nasal tissue fibroblasts (2008)

Perez Novo, Claudina, Waeytens, Anouk, Claeys, Cindy, Van Cauwenberge, Paul, Bachert, Claus

Background. Superantigens and eicosanoids are important amplifiers and regulators of inflammation in airway diseases. We therefore studied the possible influence of Staphylococcus aureus enterotoxin...

Speech Outcome regarding Overall Intelligibility, Articulation, Resonance and Voice in Flemish Children a Year after Pharyngeal Flap Surgery (2008)

Van Lierde, Kristiane, BONTE, KATRIEN, Baudonck, Nele, Van Cauwenberge, Paul, De Leenheer, Els

Objective: The main purpose of this study is to determine the treatment effectiveness of pharyngeal flap surgery by measuring speech outcome 1 year after surgery. The authors hypothesized that flap...

Staphylococcus aureus enterotoxin B, protein A, and lipoteichoic acid stimulations in nasal polyps (2008)

Patou, Joke, Gevaert, Philippe, VAN ZELE, THIBAUT, Holtappels, Gabriële, Van Cauwenberge, Paul, Bachert, Claus

Background: Increasing evidence points toward a modifying role of Staphylococcus aureus and its products in the pathogenesis of nasal polyposis. Objective: The aim of this study was to investigate...

Allergic rhinitis and its impact on asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen) (2008)

Bousquet, J., Khaltaev, N., Cruz, A. A., Denburg, J., Fokkens, W. J., Togias, A., ...

Allergic rhinitis is a symptomatic disorder of the nose induced after allergen exposure by an IgE-mediated inflammation of the membranes lining the nose. It is a global health problem that causes...

Rupatadine in allergic rhinitis and chronic urticaria (2008)

Mullo, J., Bousquet, J., Bachert, Claus, Canonica, W. G., Gimenez-Arnau, A., Kowalski, M. L., ...

Histamine is the primary mediator involved the pathophysiology of allergic rhinitis and chronic urticaria, and this explains the prominent role that histamine H-1-receptor antagonists have in the...

Does rhinitis lead to asthma? (2007)

Van Cauwenberge, Paul, Watelet, Jean-Baptiste, VAN ZELE, THIBAUT, Wang, De-Yun, Toskala, Elina, Durham, Stephen, ...

Rhinitis and asthma are commonly linked even if the precise pathological mechanisms explaining the relationship are not fully understood. Although there is increasing evidence that rhinitis may...

Herpes zoster laryngitis: case report and serological profile (2007)

Watelet, Jean-Baptiste, Evrard, Anne-Sophie, Lawson, Georges, Remacle, Marc, BONTE, KATRIEN, Van Cauwenberge, Paul, ...

Compared to herpes zoster oticus, varicella zoster virus (VZV) reactivations in immunocompetent patients are rare in laryngeal region. Usually, associated vocal cord paralyses are reported. Herein is...

Long-term treatment of persistent allergic rhinitis with levocetirizine (2007)

Klimek, Ludger, Bachert, Claus, Canonica, G. Walter, Durham, Stephen R., Mullol, Joaquim, Van Cauwenberge, Paul, ...

Background: The impact of treatment on specific aspects of health-related quality of life (HRQOL), including limitations in particular activities and quality of sleep, has not been clarified in...

Expression of eicosanoid receptors subtypes and eosinophilic inflammation: implication on chronic rhinosinusitis (2006)

Pérez-Novo, Claudina, Claeys, Cindy, Van Cauwenberge, Paul, Bachert, Claus

Abstract Background Eicosanoid receptors are G-protein-coupled receptors playing an important immunomodulatory role in airway diseases. However, there is little information on the expression of these...

Quantitative Real Time Polymerase Chain Reaction for measurement of human Interleukin – 5 receptor alpha spliced isoforms mRNA (2003)

Pérez, Claudina, Vandesompele, Jo, Vandenbroucke, Ina, Holtappels, Gabriele, Speleman, Frank, Gevaert, Philippe, ...

Abstract Background Expression of human Interleukin-5 receptor alpha (hIL-5Rα) is controlled by alternative splicing, which generates two different transcripts encoding a membrane-anchored and a...