Bezemer, D., Wolf, F. De, Boerlijst, M.C., Sighem, A. Van, Hollingsworth, T.D., Prins, M., ...
Objective: Reducing viral load, highly active antiretroviral therapy has the potential to limit onwards transmission of HIV-1 and thus help contain epidemic spread. However, increases in risk...
A hidden HIV epidemic among women in Vietnam (2008)
Nguyen, T.A., Oosterhoff, P., Hardon, A., Tran, H.N., Coutinho, R.A., Wright, P.
Background: The HIV epidemic in Vietnam is still concentrated among high risk populations, including IDU and FSW. The response of the government has focused on the recognized high risk populations,...
Tattooing, permanent makeup and piercing in Amsterdam; guidelines, legislation and monitoring (2006)
Bij, A. Van Der, Spaargaren, J., Morre, S.A., Fennema, H.S.A., Mindel, A., Coutinho, R.A., ...
Background. Recently, outbreaks of anorectal lymphogranuloma venereum (LGV) have occurred among men who have sex with men (MSM). This study identifies risk factors and clinical predictors of LGV to...
Bij, A. Van Der, Coutinho, R.A.
To evaluate the effectiveness of blood donor selection, this study reports risk profiles of donors with transfusion-transmissible infections as obtained by ongoing surveillance, 1995 through 2003, in...
Bij, A. Van Der, Zaaijer, H.L., Cuijpers, H.T.M., ...
To improve transfusion policy and to increase understanding of the spread of hepatitis C virus (HCV) in the general population, HCV infections among voluntary Dutch blood donors were examined with...
High and persistent excretion of hepatitis A virus in immunocompetent patients (2006)
Tjon, G., Coutinho, R.A., Esman, S., Wijkmans, C.J., ...
The duration and level of virus excretion in blood and faeces of patients with. hepatitis A virus (HAV) infection were studied in relation to levels of alanine aminotransferase (ALT), disease...
Stolte, I.G., Kolader, M., Fennema, H., Coutinho, R.A.
Objective: The objective of this study was to investigate whether and what sexual risk behavior is a mediator of associations between rectal gonorrhea (RG) and highly active antiretroviral...
Sonder, G.J.B., Baayen, T.D., Coutinho, R.A.
Objective: To evaluate the impact and effectiveness of risk-group vaccination against hepatitis A targeted at migrant children living in a country with low endemicity of hepatitis A. Methods:...
Lindenburg, C.E.A., Krol, A., Smit, C., Buster, M.C.A., Coutinho, R.A., Prins, M.
Objective: To study temporal changes in HIV incidence, HIV transmission routes, and both injecting and sexual risk behaviour in the open Amsterdam Cohort Study (ACS) among drug users. Initiated in...
Kolader, M.E., Bij, A. Van Der, Dierdorp, M., Fennema, J.S.A., Coutinho, R.A., ...
Molecular typing, added to epidemiological data, can better identify transmission patterns of gonorrhea in Western countries, where the incidence has recently been rising. From September 2002 to...
Molecular epidemiology of hepatitis A in Noord-Brabant, the Netherlands (2005)
Tjon, G., Wijkmans, C.J., Coutinho, R.A., Koek, A.G., Leenders, A.G.E., ...
Occupational exposure to bloodborne viruses in the Amsterdam police force, 2000-2003 (2005)
Sonder, G.J.B., Bovée, L., Coutinho, R.A., Baayen, D., Spaargaren, J.
New lymphogranuloma venereum Chlamydia trachomatis variant, Amsterdam (2005)
Spaargaren, J., Fennema, J.S.A., Morré, S.A., Coutinho, R.A.
GB virus C coinfection and HIV-1 disease progression: The Amsterdam Cohort Study (2005)
Bij, A. Van Der, Kloosterboer, N., Prins, M., Boeser-Nunnink, B., Geskus, R.B., ...
Do HIV disease progression and HAART response vary among injecting drug users in Europe? (2005)
Zangerle, R., Hernandez Aguado, I., Boufassa, F., Broers, B., Brettle, R.P., ...
Madec, Y., Boufassa, F., Porter, K., Meyer, L., ...
Vogelgriep H5N1 in Europa: vooralsnog gering gezondheidsrisico voor Nederland (2005)
Timen, A., Vliet, J.A. Van, Koopmans, M.G.M., Steenbergen, J.E. Van, Coutinho, R.A.
An outbreak of hepatitis A among homeless drug users in Rotterdam, The Netherlands (2005)
Tjon, G., Götz, H.M., Koek, A., Zwart, O. De, Coutinho, R.A., ...
Slow epidemic of lymphogranuloma venereum L2b strain (2005)
Spaargaren, J., Schachter, J., Moncada, J., Fennema, J.S.A., Pena, A.S., ...
New lymphogranuloma venereum Chlamydia trachomatis variant, Amsterdam (2005)
Spaargaren, J., Fennema, J.S.A., Morré, S.A., Coutinho, R.A.
Real-time polymerase chain reaction to diagnose lymphogranuloma venereum [letter] (2005)
Morré, S.A., Spaargaren, J., Fennema, J.S.A., Coutinho, R.A., Pena, A.S.
Slow epidemic of lymphogranuloma venereum L2b strain (2005)
Spaargaren, J., Schachter, J., Moncada, J., Fennema, J.S.A., Pena, A.S., ...
GB virus C coinfection and HIV-1 disease progression: The Amsterdam Cohort Study (2005)
Bij, A. Van Der, Kloosterboer, N., Prins, M., Boeser-Nunnink, B., Geskus, R.B., Lange, J.M.A., ...
High plasma HIV load in the CRF01-AE outbreak among injecting drug users in Finland (2005)
Kivela, P.S., Krol, A., Salminen, M.O., Geskus, R.B., Suni, J.I., Anttilla, V.J., ...
Declining trend in transmission of drug-resistant HIV-1 in Amsterdam (2004)
Bezemer, D., Jurriaans, S., Prins, M., Hoek, L. Van Der, Prins, J.M., Wolf, F. De, ...
Analysis of Chlamydia trachomatis serovar distribution changes in the Netherlands (1986-2002) (2004)
Spaargaren, J., Verhaest, I., Mooij, J.M., Smit, C., Fennema, J.S.A., Coutinho, R.A., ...
Transmission of herpes simplex virus type 2 among factory workers in Ethiopia (2004)
Kebede, Y., Dorigo-Zetsma, J.W., Mengistu, Y., Mekonnen, Y., Schaap, A., Wolday, D., ...
Performance of routine syphilis serology in the Ethiopian cohort on HIV/AIDS (2004)
Dorigo-Zetsma, J.W., Belewu, D., Meless, H., Sanders, E., Coutinho, R.A., Schaap, A., ...
Declining trend in transmission of drug-resistant HIV-1 in Amsterdam (2004)
Bezemer, D., Jurriaans, S., Prins, M., Hoek, L. Van Der, Prins, J.M., Wolf, F. De, ...
Prediction of residual time to AIDS and death based on markers and cofactors (2003)
Geskus, R.B., Miedema, F., Goudsmit, J., Reiss, P., Schuitemaker, H., Coutinho, R.A.
Persistent immune activation in HIV-1 infection is associated with progression to AIDS (2003)
Hazenberg, M.D., Otto, S.A., Roos, M.T.L., Coutinho, R.A., Lange, J.M.A., ...
Evidence of changes in sexual behaviours among male factory workers in Ethiopia (2003)
Mekonnen, Y., Aklilu, M., Tsegaye, A., Wolday, D., Geskus, R.B., ...
Mulherin, S.A., O'Brien, Th.R., Ioannidis, J.P.A., Goedert, J.J., Buchbinder, S.P., Coutinho, R.A., ...
Simple markers for initiating antiretroviral therapy among HIV-infected Ethiopians (2003)
Mekonnen, Y., Sanders, E.J., Dorigo, W., Wolday, D., Schaap, A., ...
HIV-infectie en aids in Nederland: prevalentie en incidentie, 1987-2001 (2003)
Beuker, R.J., Prins, M., Fennema, J.S.A., Coutinho, R.A., ...
Mortality impact of AIDS in Addis Ababa, Ethiopia (2003)
Sanders, E.J., Araya, T., Kebede, D., Schaap, A., Nagelkerke, N.J.D., Coutinho, R.A.
Persistent immune activation in HIV-1 infection is associated with progression to AIDS (2003)
Hazenberg, M.D., Otto, S.A., Roos, M.T.L., Coutinho, R.A., Lange, J.M.A., ...
Prediction of residual time to AIDS and death based on markers and cofactors (2003)
Geskus, R.B., Miedema, F., Goudsmit, J., Reiss, P., Schuitemaker, H., Coutinho, R.A.
Transmissie van Hepatitis-B-virus van een chirurg naar patienten gedurende vier jaar (2003)
Spijkerman, I.J.B., Doorn, L.J. Van, Jansen, M.H.W., Wijkmans, C.J., Coutinho, R.A., ...
Prediction of residual time to AIDS and death based on markers and cofactors (2003)
Geskus, R.B., Miedema, F., Goudsmit, J., Reiss, P., Schuitemaker, H., Coutinho, R.A.
Persistent immune activation in HIV-1 infection is associated with progression to AIDS (2003)
Hazenberg, M.D., Otto, S.A., Roos, M.T.L., Coutinho, R.A., Lange, J.M.A., ...
Lindenburg, C.E.A., Stolte, I.S., Langendam, M.W., Miedema, F., Williams, I.G., Colebunders, R., ...
Primary HIV-1 subtype C infection in Ethiopia (2002)
Rinke De Wit, T.F., Tsegaye, A., Wolday, D., Hailu, B., Aklilu, M., Sanders, E., ...
Lindenburg, C.E.A., Stolte, I.S., Langendam, M.W., Miedema, F., Williams, I.G., Colebunders, R., ...
Molecular epidemiology of hepatitis B virus in Amsterdam 1992-1997 (2002)
Steenbergen, J.E. Van, Niesters, H.G.M., Leentvaar-Kuijpers, A., ...
Postexpositiebehandeling tegen HIV buiten het ziekenhuis in Amsterdam, januari-december 2000 (2002)
Sonder, G.J.B., Regez, R.M., Brinkman, K., Prins, J.M., Mulder, J.W., Coutinho, R.A., ...
Primary HIV-1 subtype C infection in Ethiopia (2002)
Rinke De Wit, T.F., Tsegaye, A., Wolday, D., Hailu, B., Aklilu, M., Sanders, E., ...
Molecular epidemiology of hepatitis B virus in Amsterdam 1992-1997. (2002)
Van Steenbergen, J.E., Niesters, HG.M., Op De Coul, EL.M., Van Doornum, GJ.J., Leentvaar-Kuijpers, A., ...
Lindenburg, C.E.A., Stolte, I.S., Langendam, M.W., Miedema, F., Williams, I.G., Colebunders, R., ...
Primary HIV-1 subtype C infection in Ethiopia (2002)
Rinke De Wit, T.F., Tsegaye, A., Wolday, D., Hailu, B., Aklilu, M., Sanders, E., ...
Lindenburg, C. E. A., Stolte, I., Langendam, M. W., Miedema, F., Williams, I. G., Colebunders, R., ...
Long-term effects of therapeutic vaccination of human immunodeficiency virus (HIV)-1-infected subjects with HIV-1 p17/p24:Ty virus-like particles (p24-VLP) on progression to AIDS, death, a CD4 cell...
Factors associated with HIV-1 infection among sex workers of Addis Ababa, Ethiopia (2001)
Aklilu, M., Messele, T., Tsegaye, A., Biru, T., Mariam, D.H., ...
Persistence of Chlamydia trachomatis infections: Bacterium and host based? letter (2001)
Morre, S.A., Spaargaren, J., Schmid, G., Pe?a, A.S., Coutinho, R.A.
Ioannidis, J.P.A., Rosenberg, Ph.S., Goedert, J.J., Ashton, L.J., Benfield, T.L., Buchbinder, S.P., ...
Toename van chinolonresistentie bij Neisseria gonorrhoeae in Amsterdam (2001)
Peerbooms, P.G.H., Spaargaren, J., Fennema, J.S.A., Cairo, I., Coutinho, R.A.
Pneumococcal carriage in children in The Netherlands: A molecular epidemiological study (2001)
Bogaert, D., Engelen, M.N., Elzenaar, K.P., Perbooms, P.G.H., Coutinho, R.A., ...
Surrogate markers for disease progression in treated HIV infection (2001)
Ghani, A.C., Wolf, F. De, Ferguson, N.M., Donnelly, C.A., Coutinho, R.A., Miedema, F., ...
"Ethiopia-Netherlands aids research project" (2001)
Sanders, E.J., Rinke De Wit, T.F., Fontanet, A.L., Goudsmit, J., Miedema, F., Coutinho, R.A.
Resultaten van het "Ethiopia-Netherlands aids research project"; 1995-2000 (2001)
Rinke De Wit, T.F., Sanders, E.J., Fontanet, A.L., Goudsmit, J., Miedema, F., Coutinho, R.A.
Molecular epidemiology of hepatitis A virus in Amsterdam, the Netherlands (2001)
Bruisten, S.M., Steenbergen, J.E. Van, Pijl, A., Niesters, H.G.M., Coutinho, R.A.
Pneumococcal carriage in children in The Netherlands: a molecular epidemiological study (2001)
Bogaert, D., Engelen, M.N., Timmers-Reker, A.J., Elzenaar, K.P., Peerbooms, P.G., Coutinho, R.A., ...
In 1999, Engelen and coworkers investigated colonization in Amsterdam among 259 children attending 16 day-care centers (DCCs) and among 276 children who did not attend day-care centers (NDCCs). A...
Hazenberg, Mette D., Borleffs, J.C.C., Otto, S.A. (Sigrid), Verschuren, M.C.M. (Martie), Boucher, C.A.B., ...
Recent thymic emigrants can be identified by T cell receptor excision circles (TRECs) formed during T-cell receptor rearrangement. Decreasing numbers of TRECs have been observed with aging and in...
Shigellose in Amsterdam, 1991-1998: voorkomen en resultaten van contactonderzoek (2000)
Vermaak, M.P., Langendam, M.W., Peerbooms, P.G.H., Coutinho, R.A.
How does tuberculosis relate to HIV positive and HIV negative drug users ? (2000)
Keizer, S.T., Langendam, M.W., Deutekom, H. Van, Coutinho, R.A.
Long-term effects of therapeutic vaccination with rgp 120: letter (2000)
Lindenburg, C.E.A., Langendam, M.W., Veenstra, J., Miedema, F., Coutinho, R.A.
Baarle, D. Van, Hovenkamp, E., Renwick, N.M., Kersten, M.J., Goudsmit, J., ...
Cop. University of Chicago Press
Pontesilli, O., Carotenuto, P., Kerkhof-Garde, S.R., Roos, M.T.L., Keet, I.P.M., Coutinho, R.A., ...
Pontesilli, O., Carotenuto, P., Kerkhof-Garde, S.R., Roos, M.T.L., Keet, I.P.M., Coutinho, R.A., ...
Do gender differences in CD4 cell counts matter ? (1999)
Prins, M., Robertson, J.R., Brettle, R.P., Hernandez Aguado, I., Broers, B., Boufassa, F., ...
Houweling, H., Heisterkamp, S.H., Wiessing, L.G., Coutinho, R.A., Wijngaarden, J.K. Van, Jager, J.C.
Identification of a site for a cohort study on natural history of HIV infection in Ethiopia (1998)
Sahlu, T., Fontanet, A.L., Rinke De Wit, T.F., Messele, T., Doorly, R., Yeneneh, H., ...
A birth cohort analysis of Aids in Europe: high incidence among young persons at risk (1998)
Houweling, H., Hamers, F.F., Tremorshuizen, F., Gill, O.N., Jager, J.C., Coutinho, R.A.
Transmissie van tuberculose in Amsterdam: een onderzoek met DNA-fingerprinting (1998)
Deutekom, H. Van, Gerritsen, J.J.J., Soolingen, D. Van, Coutinho, R.A.
Tuberculose bij HIV-positieve en HIV-negatieve drugsgebruikers in Amsterdam (1998)
Keizer, S.T., Langendam, M.W., Deutekom, H. Van, Coutinho, R.A.
Longer survival after HIV infection for injecting drug users than for homosexual men ? letter (1998)
Wolf, F. De, Spijkerman, I.J.B., Schellekens, P.T.A., Langendam, M.W., Kuiken, C.L., Bakker, M., ...
Association between CCR5 genotype and the clinical course of HIV-1 infection (1997)
Koot, M., Cornelissen, M., Keet, I.P.M., Brouwer, M., Broersen, S.M., ...
Wolf, F. De, Spijkerman, I.J.B., Schellekens, P.T.A., Langendam, M.W., Kuiken, C.L., Bakker, M., ...
Association between CCR5 genotype and the clinical course of HIV-1 infection (1997)
Koot, M., Cornelissen, M., Keet, I.P.M., Brouwer, M., Broersen, S.M., ...
Wolf, F. De, Spijkerman, I.J.B., Schellekens, P.T.A., Langendam, M.W., Kuiken, C.L., Bakker, M., ...
Association between CCR5 genotype and the clinical course of HIV-1 infection (1997)
Koot, M., Cornelissen, M., Keet, I.P.M., Brouwer, M., Broersen, S.M., ...
Rapid disease progression in human immunodeficiency virus type 1-infected (1997)
Veenstra, J., Veugelers, P.J., Keet, I.P.M., Miedema, F., Lange, J.M.A., ...
Has the rate of pregression to Aids changed in recent years ? (1997)
Carre, N., Prins, M., Meyer, L., Brettle, R.P., Robertson, J.R., McArdle, H., ...
Veugelers, P.J., Kaldor, J.M., Strathdee, S.A., Page-Shafer, K.A., Schechter, M.T., Coutinho, R.A., ...
Wolf, F. De, Spijkerman, I.J.B., Schellekens, P.T.A., Langendam, M.W., Kuiken, C.L., Bakker, M., ...
Association between CCR5 genotype and the clinical course of HIV-1 infection (1997)
Koot, M., Cornelissen, M.T.E., Keet, I.P.M., Brouwer, M., Broersen, S.M., ...
Wolf, F. De, Spijkerman, I.J.B., Schellekens, P.T.A., Langendam, M.W., Kuiken, C.L., Bakker, M., ...
Association between CCR5 genotype and the clinical course of HIV-1 infection (1997)
Koot, M., Cornelissen, M., Keet, I.P.M., Brouwer, M., Broersen, S.M., ...
Wolf, F. De, Spijkerman, I.J.B., Schellekens, P.T.A., Langendam, M.W., Kuiken, C.L., Bakker, M., ...
Association between CCR5 genotype and the clinical course of HIV-1 infection (1997)
Koot, M., Cornelissen, M., Keet, I.P.M., Brouwer, M., Broersen, S.M., ...
Wolf, F. De, Spijkerman, I.J.B., Schellekens, P.T.A., Langendam, M.W., Kuiken, C.L., Bakker, M., ...
Association between CCR5 genotype and the clinical course of HIV-1 infection (1997)
Koot, M., Cornelissen, M., Keet, I.P.M., Brouwer, M., Broersen, S.M., ...
Mientjes, G. H. C., Bax, J. S., Coutinho, R. A.
The impact of human immunodeficiency virus (HIV) infection and other risk factors on mortality was studied in a cohort of Dutch injection drug users and drug users who did not inject. Participants...
Previous studies among injection drug users have reported small or nonexistent reductions in sexual risk behavior with noncommercial partners, and a large potential for further heterosexual spread of...
Background Rates of self-reported sexually transmitted diseases (STD) among drug-using prostitutes in Amsterdam have been shown to be declining. However, self reports may provide biased estimates....
Although injection drug users have been shown to reduce high-risk injection behaviors in response to the epidemic of human immunodeficiency virus (HIV) infection and ac-quired immunodeficiency...
HIV risk behavior and beliefs of HIV-seropositive drugusers (1992)
Hartgers, C., Krijnen, P., Coutinho, R.A., Pligt, J. Van Der
To assess risk factors for seroconversion to human immunodeficiency virus, the authors studied a cohort of human immunodeficiency virus-seronegative injecting drug users in Amsterdam, the...
KUIKEN, C. L., COUTINHO, R. A.
In Amsterdam, The Netherlands, a cohort of 982 homosexual and bisexual men has been studied since 1984. Of these, 238 men had antibodies to the human immunodeficiency virus at the onset of the study,...
Kuiken, C L, Zwart, G, Baan, E, Coutinho, R A, Van Den Hoek, J A, Goudsmit, J
Population-wide variation in genomic RNA of human immunodeficiency virus type 1 (HIV-1) encompassing the V3 loop of the envelope protein was studied in serum samples of 74 newly infected individuals...
Van Doornum, G J, Buimer, M, Prins, M, Henquet, C J, Coutinho, R A, Plier, P K, ...
The suitability of urine specimens from women and men for the detection of Chlamydia trachomatis infection by a ligase chain reaction (LCR)-based assay with plasmid primers was examined with a group...
Goudsmit, J, Miedema, F, Roos, M T, Schellekens, P T, Coutinho, R A, ...
Immunoglobulin G (IgG) and IgM antibodies to human T-cell leukemia/lymphoma virus-I (HTLV-I)-associated membrane antigens (HTLV-I-MA) were assayed by indirect cytospin immunofluorescence, and IgG and...
Van't Wout, A B, Kootstra, N A, Mulder-Kampinga, G A, Scherpbier, H J, Veenstra, J, ...
Macrophage-tropic, non-syncytium-inducing, HIV-1 variants predominate in the asymptomatic phase of infection and may be responsible for establishing infection in an individual exposed to the mixture...
Van Doornum, G J, Prins, M, Pronk, L, Coutinho, R A, Dillner, J
The aim of this study was to investigate whether antibody responses against synthetic peptides derived from genital human papillomavirus (HPV) proteins are associated with laboratory-proven genital...
Van Griensven, G J, De Vroome, E M, Tielman, R A, Goudsmit, J, De Wolf, F, ...
Between October 1984 and May 1986, 746 homosexual men, living in and around Amsterdam, The Netherlands, were surveyed at three consecutive six months periods regarding their sexual behavior. At the...
Risk reduction among intravenous drug users in Amsterdam under the influence of AIDS.
Van Den Hoek, J A, Van Haastrecht, H J, Coutinho, R A
We evaluated the impact of a needle/syringe exchange program among 263 drug users in the period December 1985 to April 1988. Participants in this study were asked about their risk-behavior at three...
Hartgers, C, Van Ameijden, E J, Van Den Hoek, J A, Coutinho, R A
To enhance the prevention of human immunodeficiency virus infection, factors related to regular participation in the Amsterdam Syringe Exchange and the borrowing of syringes were studied in 131...
The course of the HIV epidemic among intravenous drug users in Amsterdam, The Netherlands.
Van Haastrecht, H J, Van Den Hoek, J A, Bardoux, C, Leentvaar-Kuypers, A, Coutinho, R A
To determine if behavioral changes in intravenous drug users in Amsterdam have retarded the HIV (human immunodeficiency virus) epidemic in this group in recent years, we report that: HIV-antibody...
The impact of harm-reduction-based methadone treatment on mortality among heroin users.
Langendam, M W, Van Brussel, G H, Coutinho, R A, Van Ameijden, E J
OBJECTIVES: The purpose of this study was to investigate the impact of harm-reduction-based methadone programs on mortality among heroin users. METHODS: A prospective cohort investigation was...
Risk of AIDS related complex and AIDS in homosexual men with persistent HIV antigenaemia.
De Wolf, F, Goudsmit, J, Paul, D A, Lange, J M, Hooijkaas, C, Schellekens, P, ...
One hundred and ninety eight men seropositive for human immunodeficiency virus (HIV) antibody and 58 HIV antibody seroconverters were studied for an average of 19.3 (SEM 0.5) months to assess the...
Lange, J M, Coutinho, R A, Krone, W J, Verdonck, L F, Danner, S A, ...
Longitudinal IgG recognition patterns of viral proteins were studied in 15 men who had seroconverted for lymphadenopathy associated virus/human T lymphotropic virus (LAV/HTLV-III). Antibodies to the...
Persistent HIV antigenaemia and decline of HIV core antibodies associated with transition to AIDS.
Lange, J M, Paul, D A, Huisman, H G, De Wolf, F, Coutinho, R A, ...
Sequential serum samples from 13 homosexual men who seroconverted for antibodies to human immunodeficiency virus (HIV) were tested for HIV antigen. In one of these men, who developed the acquired...
Coutinho, R A, Lelie, N, Reerink-Brongers, E E, Stoutjesdijk, L, Dees, P, ...
The efficacy of a heat inactivated hepatitis B virus vaccine, containing 3 micrograms hepatitis B surface antigen (HBsAg), was studied in a high risk group of 800 susceptible homosexual men by a...
Prevalence and incidence of hepatitis A among male homosexuals.
Coutinho, R A, Lelie, N, Nagelkerke, N, Kuipers, H, Rijsdijk, T
In a study of 689 male homosexuals 290 (42%) were found to have antibodies to hepatitis A virus. The 399 men who did not have antibodies were followed up for up to 690 days, and 35 cases of hepatitis...
Van Ameijden, E J, Van Den Hoek, A R, Coutinho, R A
OBJECTIVES. Serial, cross-sectional trends in injecting risk behavior were studied among drug users from 1986 to 1992. METHODS. From a cohort study in Amsterdam, 616 intake visits of drug users who...
Condom use and risk factors for HIV-1 infection among female commercial sex workers in Thailand.
Limanonda, B, Van Griensven, G J, Chongvatana, N, Tirasawat, P, Coutinho, R A, Auwanit, W, ...
Mientjes, G H, Van Ameijden, E J, Weigel, H M, Van Den Hoek, J A, Coutinho, R A
OBJECTIVE--To study the clinical symptoms associated with seroconversion for HIV-1 among misusers of intravenous drugs. DESIGN--Case-control study in cohorts of drug misusers and homosexual men....
Safe sexual practices not reliably maintained by homosexual men.
De Wit, J B, De Vroome, E M, Sandfort, T G, Van Griensven, G J, Coutinho, R A, Tielman, R A
Hartgers, C, Krijnen, P, Coutinho, R A
INTRODUCTION. After the onset of the HIV epidemic, the hope arose that the "harm reduction" approach of the Amsterdam "low-threshold" methadone programs would have a function in controlling the...
Kuiken, C L, Zwart, G, Baan, E, Coutinho, R A, Van Den Hoek, J A, Goudsmit, J
Population-wide variation in genomic RNA of human immunodeficiency virus type 1 (HIV-1) encompassing the V3 loop of the envelope protein was studied in serum samples of 74 newly infected individuals...
Van Doornum, G J, Buimer, M, Prins, M, Henquet, C J, Coutinho, R A, Plier, P K, ...
The suitability of urine specimens from women and men for the detection of Chlamydia trachomatis infection by a ligase chain reaction (LCR)-based assay with plasmid primers was examined with a group...
Goudsmit, J, Miedema, F, Roos, M T, Schellekens, P T, Coutinho, R A, ...
Immunoglobulin G (IgG) and IgM antibodies to human T-cell leukemia/lymphoma virus-I (HTLV-I)-associated membrane antigens (HTLV-I-MA) were assayed by indirect cytospin immunofluorescence, and IgG and...
Van't Wout, A B, Kootstra, N A, Mulder-Kampinga, G A, Scherpbier, H J, Veenstra, J, ...
Macrophage-tropic, non-syncytium-inducing, HIV-1 variants predominate in the asymptomatic phase of infection and may be responsible for establishing infection in an individual exposed to the mixture...
Van Doornum, G J, Prins, M, Pronk, L, Coutinho, R A, Dillner, J
The aim of this study was to investigate whether antibody responses against synthetic peptides derived from genital human papillomavirus (HPV) proteins are associated with laboratory-proven genital...
Risk of AIDS related complex and AIDS in homosexual men with persistent HIV antigenaemia.
De Wolf, F, Goudsmit, J, Paul, D A, Lange, J M, Hooijkaas, C, Schellekens, P, ...
One hundred and ninety eight men seropositive for human immunodeficiency virus (HIV) antibody and 58 HIV antibody seroconverters were studied for an average of 19.3 (SEM 0.5) months to assess the...
Lange, J M, Coutinho, R A, Krone, W J, Verdonck, L F, Danner, S A, ...
Longitudinal IgG recognition patterns of viral proteins were studied in 15 men who had seroconverted for lymphadenopathy associated virus/human T lymphotropic virus (LAV/HTLV-III). Antibodies to the...
Persistent HIV antigenaemia and decline of HIV core antibodies associated with transition to AIDS.
Lange, J M, Paul, D A, Huisman, H G, De Wolf, F, Coutinho, R A, ...
Sequential serum samples from 13 homosexual men who seroconverted for antibodies to human immunodeficiency virus (HIV) were tested for HIV antigen. In one of these men, who developed the acquired...
Van Griensven, G J, De Vroome, E M, Tielman, R A, Goudsmit, J, De Wolf, F, ...
Between October 1984 and May 1986, 746 homosexual men, living in and around Amsterdam, The Netherlands, were surveyed at three consecutive six months periods regarding their sexual behavior. At the...
Risk reduction among intravenous drug users in Amsterdam under the influence of AIDS.
Van Den Hoek, J A, Van Haastrecht, H J, Coutinho, R A
We evaluated the impact of a needle/syringe exchange program among 263 drug users in the period December 1985 to April 1988. Participants in this study were asked about their risk-behavior at three...
Hartgers, C, Van Ameijden, E J, Van Den Hoek, J A, Coutinho, R A
To enhance the prevention of human immunodeficiency virus infection, factors related to regular participation in the Amsterdam Syringe Exchange and the borrowing of syringes were studied in 131...
The course of the HIV epidemic among intravenous drug users in Amsterdam, The Netherlands.
Van Haastrecht, H J, Van Den Hoek, J A, Bardoux, C, Leentvaar-Kuypers, A, Coutinho, R A
To determine if behavioral changes in intravenous drug users in Amsterdam have retarded the HIV (human immunodeficiency virus) epidemic in this group in recent years, we report that: HIV-antibody...
The impact of harm-reduction-based methadone treatment on mortality among heroin users.
Langendam, M W, Van Brussel, G H, Coutinho, R A, Van Ameijden, E J
OBJECTIVES: The purpose of this study was to investigate the impact of harm-reduction-based methadone programs on mortality among heroin users. METHODS: A prospective cohort investigation was...
Coutinho, R A, Lelie, N, Reerink-Brongers, E E, Stoutjesdijk, L, Dees, P, ...
The efficacy of a heat inactivated hepatitis B virus vaccine, containing 3 micrograms hepatitis B surface antigen (HBsAg), was studied in a high risk group of 800 susceptible homosexual men by a...
Prevalence and incidence of hepatitis A among male homosexuals.
Coutinho, R A, Lelie, N, Nagelkerke, N, Kuipers, H, Rijsdijk, T
In a study of 689 male homosexuals 290 (42%) were found to have antibodies to hepatitis A virus. The 399 men who did not have antibodies were followed up for up to 690 days, and 35 cases of hepatitis...
Van Ameijden, E J, Van Den Hoek, A R, Coutinho, R A
OBJECTIVES. Serial, cross-sectional trends in injecting risk behavior were studied among drug users from 1986 to 1992. METHODS. From a cohort study in Amsterdam, 616 intake visits of drug users who...
Condom use and risk factors for HIV-1 infection among female commercial sex workers in Thailand.
Limanonda, B, Van Griensven, G J, Chongvatana, N, Tirasawat, P, Coutinho, R A, Auwanit, W, ...
Mientjes, G H, Van Ameijden, E J, Weigel, H M, Van Den Hoek, J A, Coutinho, R A
OBJECTIVE--To study the clinical symptoms associated with seroconversion for HIV-1 among misusers of intravenous drugs. DESIGN--Case-control study in cohorts of drug misusers and homosexual men....
Safe sexual practices not reliably maintained by homosexual men.
De Wit, J B, De Vroome, E M, Sandfort, T G, Van Griensven, G J, Coutinho, R A, Tielman, R A
Hartgers, C, Krijnen, P, Coutinho, R A
INTRODUCTION. After the onset of the HIV epidemic, the hope arose that the "harm reduction" approach of the Amsterdam "low-threshold" methadone programs would have a function in controlling the...
Changes in sexual behaviour and the fall in incidence of HIV infection among homosexual men.
Van Griensven, G. J., De Vroome, E. M., Goudsmit, J., Coutinho, R. A.
To investigate the epidemiology and normal course of infection with HIV the prevalence and incidence of the infection were studied among two cohorts of homosexual men in Amsterdam in 1980-7. The...
ROOS, M TH L, MIEDEMA, F, MEINESZ, A A P, PAKKER, N G, LANGE, J M A, ...
In 219 HIV-1-infected men of the Amsterdam cohort we measured CD4+ T cell numbers and in vitro T cell responses to CD3 MoAbs with or without CD28 costimulation and phytohaemagglutinin (PHA). The...
Coutinho, R A, Krone, W J, Smit, L, Schaesberg, W, ...
To establish when lymphadenopathy associated virus or human T lymphotropic virus (LAV/HTLV-III) was introduced into the Netherlands, we studied a cohort of homosexual men who participated in a...
Prevalence of syphilis and hepatitis B among homosexual men in two saunas in Amsterdam.
Bleeker, A, Coutinho, R A, Bakker-Kok, J, Tio, D, De Koning, G A
In a pilot study by field-screening in two different sauna baths, a day-sauna and a night-sauna, 318 homosexual men were investigated for syphilis and hepatitis B surface antigen (HBsAg) and its...
Screening for syphilis among homosexual men in bars and saunas in Amsterdam.
Lumey, L H, Kok, J, Coutinho, R A
Serological screening of 1627 homosexual men visiting two saunas and two bars in Amsterdam showed that 32.2% were seroreactive for syphilis. The 18-month study period ended in June 1981. Follow-up...
Ansink-Schipper, M C, Huikeshoven, M H, Woudstra, R K, Van Klingeren, B, De Koning, G A, Tio, D, ...
In January 1981 the incidence of penicillinase producing Neisseria gonorrhoeae (PPNG) strains in Amsterdam had increased to 18% of all new cases of gonorrhoea. Auxanographic typing in combination...
Infection with cytomegalovirus in homosexual men.
Coutinho, R A, Nagelkerke, N, Kuipers, H, ...
The prevalence and incidence of cytomegalovirus (CMV) infections were studied in a group of homosexual men. Of the 710 participants, 501 (70.6%) had complement fixing antibodies to CMV on entry to...
Coutinho, R A, Schoonhoven, F J, Van Den Hoek, J A, Emsbroek, J A
In 1976-8 the incidence of syphilis in Amsterdam doubled from 41 to 88 per 100,000. Contact tracers identified two major risk groups, homosexual men with multiple partners and prostitutes using...
Rapid amplified enzyme linked immunosorbent assay evaluated for detecting herpes simplex virus.
Emsbroek, J A, Overdiek, P, Coutinho, R A
A new amplified enzyme linked immunosorbent assay (amplified ELISA) kit for detecting herpes simplex virus (HSV) antigen was evaluated. Duplicate swabs were taken from 180 patients with clinically...
Failure rate of condoms during anogenital intercourse in homosexual men.
Van Griensven, G J, De Vroome, E M, Tielman, R A, Coutinho, R A
Two hundred and seventy seven homosexual men participating in an AIDS study in Amsterdam, The Netherlands, were interviewed in July to December 1986 regarding their experiences with the use of...
Van Den Hoek, J A, Van Haastrecht, H J, Scheeringa-Troost, B, Goudsmit, J, Coutinho, R A
To assess the potential role of drug using prostitutes in the heterosexual transmission of human immunodeficiency virus (HIV), 117 prostitutes, recruited from December 1985 to November 1987 at a...
Van Den Hoek, J A, Van Der Linden, M M, Coutinho, R A
Since 1986, an increase in heterosexually acquired syphilis cases has been seen in Amsterdam. The proportion of syphilis patients who reported using hard drugs, increased from 7% in 1985 to 23% in...
Declining gonorrhoea rates in The Netherlands, 1976-88: consequences for the AIDS epidemic.
Van De Laar, M J, Pickering, J, Van Den Hoek, J A, Van Griensven, G J, Coutinho, R A, Van De Water, H P
The national notification gonorrhoea data are analysed over the period 1976-88 in conjunction with detailed data from the two STD clinics in Amsterdam in order to get an insight into the underlying...
Keet, I P, Lee, F K, Van Griensven, G J, Lange, J M, Nahmias, A, Coutinho, R A
We studied the role of genital ulcerative infections for acquisition of human immunodeficiency virus type 1 (HIV-1) infection in a cohort of 989 homosexual men in Amsterdam between October 1984 and...
Mulder, J W, Krijnen, P, Coutinho, R A, Bakker, M, Goudsmit, J, Lange, J M
beta 2-microglobulin levels were determined in the serum of 18 initially asymptomatic HIV-1 p24 antigenaemic subjects who were treated with zidovudine (+/- acyclovir) and who were followed for 2 1/2...
Evidence for a change in behaviour among heterosexuals in Amsterdam under the influence of AIDS.
Van Haastrecht, H J, Van Den Hoek, J A, Coutinho, R A
In determining the effectiveness of AIDS preventive measures among heterosexuals, trends in visits to two clinics for sexually transmitted diseases (STD) in Amsterdam between 1982 and 1989 are...
Homosexual prostitution among male drug users and its risk for HIV infection.
Van Den Hoek, J A, Van Haastrecht, H J, Coutinho, R A
OBJECTIVE--to assess whether male prostitution is an independent risk factor for HIV infection among male (intravenous and nonintravenous) drug users. DESIGN--a cross-sectional study....
The importance of ethnicity as a risk factor for STDs and sexual behaviour among heterosexuals.
Hooykaas, C, Van Der Velde, F W, Van Der Linden, M M, Van Doornum, G J, Coutinho, R A
OBJECTIVES--To study risk factors for sexually transmitted diseases (STDs) and sexual behaviour. Especially to assess whether there is a higher risk of being infected with STDs among ethnic...
Decreasing incidence of PID in Amsterdam.
Coutinho, R A, Rijsdijk, A J, Van Den Hoek, J A, Leentvaar-Kuijpers, A
OBJECTIVE--To study the incidence of pelvic inflammatory disease (PID) in Amsterdam in the period 1983-1990. METHODS--Patients diagnosed with PID based on a clinical definition were reported weekly...
Fennema, J S, Van Ameijden, E J, Coutinho, R A, Van Doornum, G J, Henquet, C J, Van Den Hoek, J A
INTRODUCTION--Patients attending a clinic for sexually transmitted diseases (STD) in general have engaged in at risk sexual behaviour. Therefore they are at increased risk of acquiring HIV through...
Van Haastrecht, H J, Fennema, J S, Coutinho, R A, Van Der Helm, T C, Kint, J A, Van Den Hoek, J A
OBJECTIVES--To study groups of prostitutes and clients of prostitutes in order (i) to determine HIV prevalence and sexual risk behaviour, (ii) to determine differences between samples recruited...
Van Doornum, G J, Prins, M, Juffermans, L H, Hooykaas, C, Van Den Hoek, J A, Coutinho, R A, ...
OBJECTIVE--To assess prevalence, incidence and potential risk factors of human papillomavirus (HPV) infection among heterosexual men and women with multiple partners and to identify niches of...
Prins, M, Bindels, P J, Coutinho, R A, Henquet, C J, Van Doornum, G J, Van Den Hoek, J A
BACKGROUND AND OBJECTIVES--At the STD clinic of the Municipal Health Service in Amsterdam, the annual number of infections with penicillinase-producing Neisseria gonorrhoeae (PPNG) strains remained...
Hopperus Buma, A P, Veltink, R L, Van Ameijden, E J, Tendeloo, C H, Coutinho, R A
OBJECTIVES--To determine the sexual risk behaviour and the incidence of sexually transmitted diseases (STD) among Dutch marines and naval personnel during a United Nations (UN) deployment....
Differences in clinical manifestations of genital chlamydial infections related to serovars.
Van De Laar, M J, Van Duynhoven, Y T, Fennema, J S, Ossewaarde, J M, Van Den Brule, A J, Van Doornum, G J, ...
OBJECTIVES: To study the association of serovars of Chlamydia trachomatis with clinical manifestations of genital tract infection and socio-demographic characteristics. METHODS: In 1986-88 the C...
Kok, A, Zuure, F R, Coutinho, R A, Prins, M
The aim of this study was to gain insight in transmission routes of hepatitis C virus (HCV) infection among never-injecting drug users (DU) by studying, incidence, prevalence, determinants and...