R. Buettner

Details der Publikationsliste

Zeitraum

1994 - 2007

Anzahl

48

Co-Autoren

Defining high-fat-diet rat models: metabolic and molecular effects of different fat types (2006)

Buettner, R., Parhofer, K. G., Woenckhaus, M., Wrede, C. E., Kunz-Schughart, L. A., Schölmerich, J., ...

High-fat (HF)-diet rodent models have contributed significantly to the analysis of the pathophysiology of the insulin resistance syndrome, but their phenotype varies distinctly between different...

Association between serum ferritin and the insulin resistance syndrome in a representative population (2006)

Wrede, C. E., Buettner, R., Bollheimer, L. C., Schölmerich, J., Hellerbrand, C.

OBJECTIVE: Unexplained hepatic iron overload with increased serum ferritin (SF) values has been associated with the insulin resistance syndrome (IRS), defined by the presence of one or more of the...

Specific expression and regulation of the new melanoma inhibitory activity-related gene MIA2 in hepatocytes (2003)

Bosserhoff,A. K., Moser,M., Schölmerich,J., Buettner,R., Hellerbrand,C.

The novel human gene MIA2 encoding a melanoma inhibitory activity (MIA) homologous protein was identified by a GenBank(TM) search. MIA2, together with MIA, OTOR, and TANGO, belongs to the novel MIA...

Terminal renal failure in mice lacking transcription factor AP-2 beta (2003)

Moser,M., Dahmen,S., Kluge,R., Gröne,H., Dahmen,J., Kunz,D., ...

Inactivation of the transcription factor AP-2beta in a genetically mixed C57BU6/129S1 mouse strain resulted in perinatal lethality as a consequence of massively enhanced apoptotic death of renal...

Backbone dynamics of the human MIA protein studied by N-15 NMR relaxation: Implications for extended interactions of SH3 domains (2003)

Stoll,R., Renner,C., Buettner,R., Voelter,W., Bosserhoff,A. K., Holak,T. A.

The melanoma inhibitory activity (MIA) protein is a clinically valuable marker in patients with malignant melanoma as enhanced values diagnose metastatic melanoma stages III and IV. Here, we report...

Backbone dynamics of the human MIA protein studied by N-15 NMR relaxation: Implications for extended interactions of SH3 domains (2003)

Stoll, R., Renner, C., Buettner, R., Voelter, W., Bosserhoff, A. K., Holak, T. A.

The melanoma inhibitory activity (MIA) protein is a clinically valuable marker in patients with malignant melanoma as enhanced values diagnose metastatic melanoma stages III and IV. Here, we report...

Specific expression and regulation of the new melanoma inhibitory activity-related gene MIA2 in hepatocytes (2003)

Bosserhoff, A. K., Moser, M., Schölmerich, J., Buettner, R., Hellerbrand, C.

The novel human gene MIA2 encoding a melanoma inhibitory activity (MIA) homologous protein was identified by a GenBank(TM) search. MIA2, together with MIA, OTOR, and TANGO, belongs to the novel MIA...

Terminal renal failure in mice lacking transcription factor AP-2 beta (2003)

Moser, M., Dahmen, S., Kluge, R., Gröne, H., Dahmen, J., Kunz, D., ...

Inactivation of the transcription factor AP-2beta in a genetically mixed C57BU6/129S1 mouse strain resulted in perinatal lethality as a consequence of massively enhanced apoptotic death of renal...

Cloning and in situ localization of a brain-derived porin that constitutes a large-conductance anion channel in astrocytic plasma membranes.

Dermietzel, R, Hwang, T K, Buettner, R, Hofer, A, Dotzler, E, Kremer, M, ...

We have cloned a protein from bovine brain, brain-derived voltage-dependent anion channel 1 (BR1-VDAC), that is identical to a recently sequenced plasmalemmal-bound porin from human lymphocytes. mRNA...

Cloning and characterization of a fourth human somatostatin receptor.

Rohrer, L, Raulf, F, Bruns, C, Buettner, R, Hofstaedter, F, Schüle, R

We have isolated a gene coding for a fourth human somatostatin (somatotropin release-inhibiting factor) receptor. This additional somatostatin receptor (hSSTR4) is specifically expressed in human...

Identification of a retinoic acid-inducible endogenous retroviral transcript in the human teratocarcinoma-derived cell line PA-1.

Kannan, P, Buettner, R, Pratt, D R, Tainsky, M A

Retinoic acid (RA), a developmental morphogen, causes activation of a transcript of an endogenous retrovirus-related element in the human teratocarcinoma-derived cell line PA-1. This provirus is...

The genomic structure of the human AP-2 transcription factor.

Bauer, R, Imhof, A, Pscherer, A, Kopp, H, Moser, M, Seegers, S, ...

The transcription factor AP-2 is encoded by a gene located on chromosome 6 near the HLA locus. Here we describe the genomic organization of the AP-2 gene including an initial characterization of the...

An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2.

Buettner, R, Kannan, P, Imhof, A, Bauer, R, Yim, S O, Glockshuber, R, ...

AP-2 is a retinoic acid-inducible and developmentally regulated activator of transcription. We have cloned an alternative AP-2 transcript (AP-2B) from the human teratocarcinoma cell line PA-1, which...

Alteration of homeobox gene expression by N-ras transformation of PA-1 human teratocarcinoma cells.

Buettner, R, Yim, S O, Hong, Y S, Boncinelli, E, Tainsky, M A

We used a series of cell clones from a human teratocarcinoma cell line, PA-1, to study the effect of transformation by an activated N-ras oncogene on the expression of genes involved in retinoic acid...

Transcriptional activation by Myc is under negative control by the transcription factor AP-2.

Gaubatz, S, Imhof, A, Dosch, R, Werner, O, Mitchell, P, Buettner, R, ...

The Myc protein binds to and transactivates the expression of genes via E-box elements containing a central CAC(G/A)TG sequence. The transcriptional activation function of Myc is required for its...

The helix-loop-helix transcription factor SEF-2 regulates the activity of a novel initiator element in the promoter of the human somatostatin receptor II gene.

Pscherer, A, Dörflinger, U, Kirfel, J, Gawlas, K, Rüschoff, J, Buettner, R, ...

The effects of somatostatin hormones are mediated by a family of five different seven-helix transmembrane spanning receptors (SSTR1-5). The expression of the five different SSTR subtypes displays a...

LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1.

Weiskirchen, R, Moser, M, Weiskirchen, S, Erdel, M, Dahmen, S, Buettner, R, ...

Activation of hepatic stellate cells is considered to be the main step in the development of liver fibrosis, which is characterized by the transition of quiescent vitamin-A-rich cells to...

Cloning and in situ localization of a brain-derived porin that constitutes a large-conductance anion channel in astrocytic plasma membranes.

Dermietzel, R, Hwang, T K, Buettner, R, Hofer, A, Dotzler, E, Kremer, M, ...

We have cloned a protein from bovine brain, brain-derived voltage-dependent anion channel 1 (BR1-VDAC), that is identical to a recently sequenced plasmalemmal-bound porin from human lymphocytes. mRNA...

Cloning and characterization of a fourth human somatostatin receptor.

Rohrer, L, Raulf, F, Bruns, C, Buettner, R, Hofstaedter, F, Schüle, R

We have isolated a gene coding for a fourth human somatostatin (somatotropin release-inhibiting factor) receptor. This additional somatostatin receptor (hSSTR4) is specifically expressed in human...

Identification of a retinoic acid-inducible endogenous retroviral transcript in the human teratocarcinoma-derived cell line PA-1.

Kannan, P, Buettner, R, Pratt, D R, Tainsky, M A

Retinoic acid (RA), a developmental morphogen, causes activation of a transcript of an endogenous retrovirus-related element in the human teratocarcinoma-derived cell line PA-1. This provirus is...

The genomic structure of the human AP-2 transcription factor.

Bauer, R, Imhof, A, Pscherer, A, Kopp, H, Moser, M, Seegers, S, ...

The transcription factor AP-2 is encoded by a gene located on chromosome 6 near the HLA locus. Here we describe the genomic organization of the AP-2 gene including an initial characterization of the...

An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2.

Buettner, R, Kannan, P, Imhof, A, Bauer, R, Yim, S O, Glockshuber, R, ...

AP-2 is a retinoic acid-inducible and developmentally regulated activator of transcription. We have cloned an alternative AP-2 transcript (AP-2B) from the human teratocarcinoma cell line PA-1, which...

Alteration of homeobox gene expression by N-ras transformation of PA-1 human teratocarcinoma cells.

Buettner, R, Yim, S O, Hong, Y S, Boncinelli, E, Tainsky, M A

We used a series of cell clones from a human teratocarcinoma cell line, PA-1, to study the effect of transformation by an activated N-ras oncogene on the expression of genes involved in retinoic acid...

Transcriptional activation by Myc is under negative control by the transcription factor AP-2.

Gaubatz, S, Imhof, A, Dosch, R, Werner, O, Mitchell, P, Buettner, R, ...

The Myc protein binds to and transactivates the expression of genes via E-box elements containing a central CAC(G/A)TG sequence. The transcriptional activation function of Myc is required for its...

The helix-loop-helix transcription factor SEF-2 regulates the activity of a novel initiator element in the promoter of the human somatostatin receptor II gene.

Pscherer, A, Dörflinger, U, Kirfel, J, Gawlas, K, Rüschoff, J, Buettner, R, ...

The effects of somatostatin hormones are mediated by a family of five different seven-helix transmembrane spanning receptors (SSTR1-5). The expression of the five different SSTR subtypes displays a...

LIM-domain protein cysteine- and glycine-rich protein 2 (CRP2) is a novel marker of hepatic stellate cells and binding partner of the protein inhibitor of activated STAT1.

Weiskirchen, R, Moser, M, Weiskirchen, S, Erdel, M, Dahmen, S, Buettner, R, ...

Activation of hepatic stellate cells is considered to be the main step in the development of liver fibrosis, which is characterized by the transition of quiescent vitamin-A-rich cells to...

Overexpression of melanoma inhibitory activity (MIA) enhances extravasation and metastasis of A-mel 3 melanoma cells in vivo

Guba, M, Bosserhoff, A-K, Steinbauer, M, Abels, C, Anthuber, M, Buettner, R, ...

The secreted MIA protein is strongly expressed by advanced primary and metastatic melanomas but not in normal melanocytes. Previous studies have shown that MIA serum levels correlate with clinical...