Evans, J.A., May, J., Tominski, D., Eggelte, T., Marks, F., Abruquah, H.H., ...
Background: Self-medication with anti-malarial drugs is widespread, and chloroquine (CQ) resistance is increasing. The effect of these factors on the incidence and presentation of severe malaria is...
Evans, J.A., May, J., Tominski, D., Eggelte, T., Marks, F., Abruquah, H.H., ...
Background: Self-medication with anti-malarial drugs is widespread, and chloroquine (CQ) resistance is increasing. The effect of these factors on the incidence and presentation of severe malaria is...
Evans, J.A., May, J., Tominski, D., Eggelte, T., Marks, F., Abruquah, H.H., ...
Background: Self-medication with anti-malarial drugs is widespread, and chloroquine (CQ) resistance is increasing. The effect of these factors on the incidence and presentation of severe malaria is...
C Timmann, S Fuchs, C Thoma, B Lepping, N W Brattig, J Sievertsen, ...
High mortality of infant bacteraemia clinically indistinguishable from severe malaria (2004)
Evans, J.A., Adusei, A., Timmann, C., May, J., Mack, D., Agbenyega, T., ...
Background: Early recognition of children at highest risk of dying and the targeting of appropriate drug therapy are vital to the improvement of paediatric care in developing countries. This will...
Leippe, M., Tannich, E., Nickel, R., Van Der Goot, G., Pattus, F., Horstmann, R. D., ...
A pore-forming peptide is implicated in the potent cytolytic activity of pathogenic Entamoeba histolytica. Using NH2-terminal sequence information of this peptide, the corresponding cDNA was...
Genomic DNA differences between pathogenic and nonpathogenic Entamoeba histolytica (1989)
Arnold, H.-H., Horstmann, R.D., Knobloch, J., Tannich, E.
DNA libraries were constructed from pathogenic (HM-1:IMSS) and nonpathogenic (SAW 1734) isolates of Entamoeba histolytica. A cDNA clone (cEH-P1) specific for pathogenic amoebae was identified by...
Meyer, C G, Gallin, M, Erttmann, K D, Brattig, N, Schnittger, L, Gelhaus, A, ...
Human infections with the tissue nematode Onchocerca volvulus result in a variety of clinical conditions that possibly include protective immunity. In a West African area hyperendemic for human...
Primary structure of the 170-kDa surface lectin of pathogenic Entamoeba histolytica.
Tannich, E, Ebert, F, Horstmann, R D
The adherence of Entamoeba histolytica to colonic mucins and to host cells appears to be predominantly mediated by a 170-kDa surface lectin of the amoebae. By using an antiserum to the purified...
Pore-forming peptide of pathogenic Entamoeba histolytica.
Leippe, M, Ebel, S, Schoenberger, O L, Horstmann, R D, Müller-Eberhard, H J
A polypeptide that causes pore formation in target-cell membranes is implicated in the potent cytolytic activity of pathogenic Entamoeba histolytica. Pore-forming material was purified to apparent...
Location of the complement factor H binding site on streptococcal M6 protein.
Fischetti, V A, Horstmann, R D, Pancholi, V
The surface M protein of group A streptococci binds factor H, a regulatory protein of the alternative complement pathway, which may contribute to the antiphagocytic activity of the M molecules. To...
Role of fibrinogen in complement inhibition by streptococcal M protein.
Horstmann, R D, Sievertsen, H J, Leippe, M, Fischetti, V A
M protein, the major virulence factor of group A streptococci, has antiopsonic activity in that it inhibits activation of the alternative complement pathway on the streptococcal surface. Two...
Horstmann, R D, Sievertsen, H J, Knobloch, J, Fischetti, V A
Isolated complement components were used to study the regulation of the alternative complement pathway C3 convertase (EC 3.4.21.47), also called C3b,Bb, on M protein-carrying (M+) and M...
Hamelmann, C, Urban, B, Foerster, B, Horstmann, R D
Pathogenic forms of the protozoan parasite Entamoeba histolytica were reported previously to resist the cytolytic effect of the alternative complement pathway (AP) only temporarily during exposure to...
Genomic DNA differences between pathogenic and nonpathogenic Entamoeba histolytica.
Tannich, E, Horstmann, R D, Knobloch, J, Arnold, H H
cDNA libraries were constructed from pathogenic (HM-1:IMSS) and nonpathogenic (SAW 1734) isolates of Entamoeba histolytica. A cDNA clone (cEH-P1) specific for pathogenic amoebae was identified by...
The Species Mycobacterium africanum in the Light of New Molecular Markers
Niemann, S., Kubica, T., Bange, F. C., Adjei, O., Browne, E. N., Chinbuah, M. A., ...
The findings of recent studies addressing the molecular characteristics of Mycobacterium tuberculosis complex isolates have initiated a discussion on the classification of M. africanum, especially of...
Primary and secondary structure of the pore-forming peptide of pathogenic Entamoeba histolytica.
Leippe, M, Tannich, E, Nickel, R, Van Der Goot, G, Pattus, F, Horstmann, R D, ...
A pore-forming peptide is implicated in the potent cytolytic activity of pathogenic Entamoeba histolytica. Using NH2-terminal sequence information of this peptide, the corresponding cDNA was...
Meyer, C G, Gallin, M, Erttmann, K D, Brattig, N, Schnittger, L, Gelhaus, A, ...
Human infections with the tissue nematode Onchocerca volvulus result in a variety of clinical conditions that possibly include protective immunity. In a West African area hyperendemic for human...
Primary structure of the 170-kDa surface lectin of pathogenic Entamoeba histolytica.
Tannich, E, Ebert, F, Horstmann, R D
The adherence of Entamoeba histolytica to colonic mucins and to host cells appears to be predominantly mediated by a 170-kDa surface lectin of the amoebae. By using an antiserum to the purified...
Pore-forming peptide of pathogenic Entamoeba histolytica.
Leippe, M, Ebel, S, Schoenberger, O L, Horstmann, R D, Müller-Eberhard, H J
A polypeptide that causes pore formation in target-cell membranes is implicated in the potent cytolytic activity of pathogenic Entamoeba histolytica. Pore-forming material was purified to apparent...
Location of the complement factor H binding site on streptococcal M6 protein.
Fischetti, V A, Horstmann, R D, Pancholi, V
The surface M protein of group A streptococci binds factor H, a regulatory protein of the alternative complement pathway, which may contribute to the antiphagocytic activity of the M molecules. To...
Role of fibrinogen in complement inhibition by streptococcal M protein.
Horstmann, R D, Sievertsen, H J, Leippe, M, Fischetti, V A
M protein, the major virulence factor of group A streptococci, has antiopsonic activity in that it inhibits activation of the alternative complement pathway on the streptococcal surface. Two...
Horstmann, R D, Sievertsen, H J, Knobloch, J, Fischetti, V A
Isolated complement components were used to study the regulation of the alternative complement pathway C3 convertase (EC 3.4.21.47), also called C3b,Bb, on M protein-carrying (M+) and M...
Hamelmann, C, Urban, B, Foerster, B, Horstmann, R D
Pathogenic forms of the protozoan parasite Entamoeba histolytica were reported previously to resist the cytolytic effect of the alternative complement pathway (AP) only temporarily during exposure to...
Genomic DNA differences between pathogenic and nonpathogenic Entamoeba histolytica.
Tannich, E, Horstmann, R D, Knobloch, J, Arnold, H H
cDNA libraries were constructed from pathogenic (HM-1:IMSS) and nonpathogenic (SAW 1734) isolates of Entamoeba histolytica. A cDNA clone (cEH-P1) specific for pathogenic amoebae was identified by...
The Species Mycobacterium africanum in the Light of New Molecular Markers
Niemann, S., Kubica, T., Bange, F. C., Adjei, O., Browne, E. N., Chinbuah, M. A., ...
The findings of recent studies addressing the molecular characteristics of Mycobacterium tuberculosis complex isolates have initiated a discussion on the classification of M. africanum, especially of...
Primary and secondary structure of the pore-forming peptide of pathogenic Entamoeba histolytica.
Leippe, M, Tannich, E, Nickel, R, Van Der Goot, G, Pattus, F, Horstmann, R D, ...
A pore-forming peptide is implicated in the potent cytolytic activity of pathogenic Entamoeba histolytica. Using NH2-terminal sequence information of this peptide, the corresponding cDNA was...
Relevance of ex vivo blood lymphocyte assay for in vivo lymphocyte function
Brattig, N W, Timmann, C, Abraha, R S, Lepping, B, Müller-Myhsok, B, Horstmann, R D
Determinations of in vitro proliferative and secretory activities of peripheral blood cells are used widely for research in clinical immunology but, to our knowledge, have not been evaluated as to...