Polymorphisms in the Angiotensin-Converting Enzyme Gene Region Predict Coping Styles in Healthy Adults and Depressed Patients (2009)
Heck, A.,
Lieb, R.,
Ellgas, A.,
Pfister, H.,
Lucae, S.,
Erhardt, A.,
...
DO CANNABIS AND URBANICITY INTERACT IN CAUSING PSYCHOSIS? (2009)
Henquet, C.,
Kuepper, R.,
Konings, M.,
Lieb, R.,
Wittchen, H. U.,
Van Os, J.
THE ROLE OF PARENTAL PSYCHOPATHOLOGY AND FAMILY ENVIRONMENT FOR SOCIAL PHOBIA IN THE FIRST THREE DECADES OF LIFE (2009)
Knappe, S.,
Lieb, R.,
Beesdo, K.,
Fehm, L.,
Low, N. C. P.,
Gloster, A. T.,
...
A typology of cannabis-related problems among individuals with repeated illegal drug use in the first three decades of life: Evidence for heterogeneity and different treatment needs (2009)
Wittchen, H. U.,
Behrendt, S.,
Hoefler, M.,
Perkonigg, A.,
Rehm, J.,
Lieb, R.,
...
Gene-Environment Interaction of the Leptin Receptor (LEPR) Gene and Severe Trauma Moderates Depressive Symptoms and HPA-Axis Function (2009)
Zimmermann, P.,
Brückl, T.,
Pfister, H.,
Ising, M.,
Wittchen, H. U.,
Lieb, R.,
...
Investigation of 17 candidate genes for personality traits confirms effects of the HTR2A gene on novelty seeking (2009)
Heck, A.,
Lieb, R.,
Ellgas, A.,
Pfister, H.,
Lucae, S.,
Roeske, D.,
...
Reduced memory and attention performance in a population-based sample of young adults with a moderate lifetime use of cannabis, ecstasy and alcohol (2009)
Indlekofer, F.,
Piechatzek, M.,
Daamen, M.,
Glasmacher, C.,
Lieb, R.,
Pfister, H.,
...
Mood episodes and mood disorders: patterns of incidence and conversion in the first three decades of life (2009)
Beesdo, K.,
Höfler, M.,
Leibenluft, E.,
Lieb, R.,
Bauer, M.,
Pfennig, A.
Do parental psychopathology and unfavorable family environment predict the persistence of social phobia? (2009)
Knappe, S.,
Beesdo, K.,
Fehm, L.,
Höfler, M.,
Lieb, R.,
Wittchen, H. U.
Prevalence of mental disorders in acromegaly: a cross-sectional study in 81 acromegalic patients (2009)
Sievers, C.,
Dimopoulou, C.,
Pfister, H.,
Lieb, R.,
Steffin, B.,
Roemmler, J.,
...
Polymorphisms in the serotonin receptor 2A gene (HTR2A), parenting styles and the risk of depression in young adulthood: results from a family study (2009)
Brückl, T.,
Lieb, R.,
Pfister, H.,
Wittchen, H. U.,
Holsboer, F.,
Ising, M.,
...
The interplay of variations in the FKBP5 gene and adverse life events in predicting the first onset of depression during a ten-year follow-up (2009)
Zimmermann, P.,
Brückl, T.,
Pfister, H.,
Lieb, R.,
Wittchen, H. U.,
Holsboer, F.,
...
Association of polymorphisms in the angiotensin-converting enzyme gene with syndromal panic attacks (2008)
Erhardt, A.,
Lucae, S.,
Kern, N.,
Unschuld, P. G.,
Ising, M.,
Lieb, R.,
...
The natural course of cannabis use, abuse and dependence during the first decades of life (2008)
Perkonigg, A.,
Goodwin, R. D.,
Fiedler, A.,
Behrendt, S.,
Beesdo, K.,
Lieb, R.,
...
Agoraphobia and panic (2008)
Wittchen, H. U.,
Nocon, A.,
Beesdo, K.,
Pine, D. S.,
Höfler, M.,
Lieb, R.,
...
The interplay of familial depression liability and adverse events in predicting the first onset of depression during a 10-year follow-up (2008)
Zimmermann, P.,
Brückl, T.,
Lieb, R.,
Nocon, A.,
Ising, M.,
Beesdo, K.,
...
Differential familial liability of panic disorder and agoraphobia (2008)
Nocon, A.,
Wittchen, H. U.,
Beesdo, K.,
Brückl, T.,
Höfler, M.,
Pfister, H.,
...
What are the high risk periods for incident substance use and transitions to abuse and dependence? Implications for early intervention and prevention (2008)
Wittchen, H. U.,
Behrendt, S.,
Höfler, M.,
Perkonigg, A.,
Lieb, R.,
Bühringer, G.,
...
Risk and speed of transitions to first alcohol dependence symptoms in adolescents: a 10-year longitudinal community study in Germany (2008)
Behrendt, S.,
Wittchen, H. U.,
Höfler, M.,
Lieb, R.,
Low, N. C. P.,
Rehm, J.,
...
Evidence for associations between PDE4D polymorphisms and a subtype of neuroticism (2008)
Heck, A.,
Lieb, R.,
Unschuld, P.,
Ellgas, A.,
Pfister, H.,
Lucae, S.,
...
Severe trauma moderates the relationship between variations in the vasopressin receptor 1A gene (AVPR1A) and depression in a family-based association lest (2008)
Zimmermann, P.,
Brückl, T.,
Pfister, H.,
Wittchen, H. U.,
Lieb, R.,
Holsboer, F.,
...
Combined Effects of Exonic Polymorphisms in CRHR1 and AVPR1B Genes in a Case/Control Study for Panic Disorder (2008)
Keck, M. E.,
Kern, N.,
Erhardt, A.,
Unschuld, P. G.,
Ising, M.,
Salyakina, D.,
...
Accumulating evidence from animal studies suggests that the corticotropin releasing hormone (CRH) and arginine vasopressin (AVP) neuropeptide systems, contribute to anxiety behavior. To investigate...
Relationship of panic and agoraphobia: rethinking of a diagnostic concept? (2008)
Nocon, A.,
Wittchen, H. U.,
Beesdo, K.,
Pine, D. S.,
Höfler, M.,
Lieb, R.,
...
The role of the dopamine beta-hydroxylase (DBH) gene in human cognitive function (2008)
Reppermund, S.,
Lieb, R.,
Heck, A.,
Ellgas, A.,
Lucae, S.,
Holsboer, F.,
...
Relationship of variations in the leptin receptor (LEPR) gene and depressive symptoms is moderated by severe trauma (2008)
Zimmermann, P.,
Kloiber, S.,
Brueckl, T.,
Pfister, H.,
Wittchen, H. U.,
Holsboer, F.,
...
Incidence of social anxiety disorder and the consistent risk for secondary depression in the first three decades of life (2007)
Beesdo, K.,
Bittner, A.,
Pine, D. S.,
Stein, M. B.,
Höfler, M.,
Lieb, R.,
...
Does normal developmental expression of psychosis combine with environmental risk to cause persistence of psychosis? A psychosis proneness-persistence model (2007)
Cougnard, A.,
Marcelis, M.,
Myin-Germeys, I.,
De Graaf, R.,
Vollebergh, W.,
Krabbendam, L.,
...
Association of polymorphisms in P2RX7 and CaMKKb with anxiety disorders (2007)
Erhardt, A.,
Lucae, S.,
Unschuld, P. G.,
Ising, M.,
Kern, N.,
Salyakina, D.,
...
Polymorphisms in the angiotensin-converting enzyme gene region predict coping styles in healthy adults and depressed patients (2007)
Heck, A.,
Lieb, R.,
Ellgas, A.,
Pfister, H.,
Lucae, S.,
Erhardt, A.,
...
SNPs in the NTRK2 gene are associated with depressive disorder (2007)
Kohli, M. A.,
Salyakina, D.,
Binder, E. B.,
Lucae, S.,
Ising, M.,
Ripke, S.,
...
A shifted psychopathological risk profile in acromegalic patients? (2007)
Sievers, C.,
Dimopoulou, C.,
Pfister, H.,
Lieb, R.,
Steffin, B.,
Roemmler, J.,
...
Acromegalic patients: more depressed, without panic? The 'endocrine psychosyndrome' of romegaly revised (2007)
Sievers, C.,
Dimopoulou, C.,
Pfister, H.,
Lieb, R.,
Steffin, B.,
Roemmler, J.,
...
Physical activity and prevalence and incidence of mental disorders in adolescents and young adults (2007)
Ströhle, A.,
Höfler, M.,
Pfister, H.,
Müller, A. G.,
Hoyer, J.,
Wittchen, H. U.,
...
Polymorphisms in the serotonin receptor gene HTR2A are associated with quantitative traits in panic disorder (2007)
Unschuld, P. G.,
Ising, M.,
Erhardt, A.,
Lucae, S.,
Kloiber, S.,
Kohli, M.,
...
Polymorphisms in the galanin gene are associated with symptom-severity in female patients suffering from panic disorder (2007)
Unschuld, P. G.,
Ising, M.,
Erhardt, A.,
Lucae, S.,
Kohli, M.,
Kloiber, S.,
...
Cannabis use and cannabis use disorders and their relationship to mental disorders: A 10-year prospective-longitudinal community study in adolescents (2007)
Wittchen, H. U.,
Fröhlich, C.,
Behrendt, S.,
Gunther, A.,
Rehm, J.,
Zimmermann, P.,
...
Mania, hypomania, and suicidality: findings from a prospective community study (2006)
Bronisch, T.,
Schwender, L.,
Hoefler, M.,
Wittchen, H. U.,
Lieb, R.
Pathways into ecstasy use: the role of prior cannabis use and ecstasy availability (2006)
Wittchen, H. U.,
Zimmermann, P.,
Waszak, F.,
Nocon, A.,
Höfler, M.,
Lieb, R.
Substance use and substance use disorders in a community sample of adolescents and young adults: Incidence, age effects and patterns of use (2006)
Perkonigg, A.,
Pfister, H.,
Höfler, M.,
Fröhlich, C.,
Zimmermann, P.,
Lieb, R.,
...
Longitudinal course of posttraumatic stress disorder and posttraumatic stress disorder symptoms in a community sample of adolescents and young adults (2006)
Perkonigg, A.,
Pfister, H.,
Stein, M. B.,
Hoefler, M.,
Lieb, R.,
Maercker, A.,
...
Where have they been? Service use of regular substance users with and without abuse and dependence (2006)
Perkonigg, A.,
Settele, A.,
Pfister, H.,
Höfler, M.,
Fröhlich, C.,
Zimmermann, P.,
...
Genetic implications of the endocannabinoid system in anxiety disorders versus depressive disorders: is there any evidence for the continuum hypothesis? (2005)
Erhardt, A.,
Seaman, S. R.,
Lucae, S.,
Kern, N.,
Unschuld, P. G.,
Welt, T.,
...
Genetic implications of the endocannabinoid system in anxiety disorders versus depressive disorders: Is there any evidence for the continuum hypothesis? (2005)
Erhardt, A.,
Seaman, S. R.,
Lucae, S.,
Unschuld, P. G.,
Kern, N.,
Welt, T.,
...
"Anxietas Tibiarum" - Depression and anxiety disorders in patients with restless legs syndrome (2005)
Winkelmann, J.,
Prager, M.,
Lieb, R.,
Pfister, H.,
Spiegel, B.,
Wittchen, H. U.,
...
What characteristics of primary anxiety disorders predict subsequent major depressive disorder? (2004)
Bittner, A.,
Goodwin, R. D.,
Wittchen, H. U.,
Beesdo, K.,
Höfler, M.,
Lieb, R.
Panic attack as a risk factor for severe psychopathology (2004)
Goodwin, R. D.,
Lieb, R.,
Hoefler, M.,
Pfister, H.,
Bittner, A.,
Beesdo, K.,
...
How association chain graphs can model pathways into disorders (vol 13, pg 77, 2003) (2004)
Höfler, M.,
Lieb, R.,
Hoyer, J.,
Friis, R. H.,
Wittchen, H. U.
Prevalence, co-morbidity and correlates of mental disorders in the general population: results from the German Health Interview and Examination Survey (GHS) (2004)
Jacobi, F.,
Wittchen, H. U.,
Holting, C.,
Höfler, M.,
Pfister, H.,
Müller, N.,
...
Is generalized anxiety disorder a chronic disorder? Predicting chronicity and spontaneous remission (2004)
Beesdo, K.,
Wittchen, H. U.,
Höfler, M.,
Pfister, H.,
Bittner, A.,
Lieb, R.
Primary anxiety disorders and the development of subsequent alcohol use disorders: a 4-year community study of adolescents and young adults (2003)
Wittchen, H U,
Höfler, M,
Pfister, H,
Kessler, R C,
Lieb, R
BACKGROUND: Cross-sectional findings in community surveys of adults suggest that adolescent anxiety disorders are strong predictors of the subsequent onset of alcohol use, abuse and dependence....
Recurrent brief depressive disorder reinvestigated: a community sample of adolescents and young adults (2003)
Pezawas, L.,
Wittchen, H. U.,
Pfister, H.,
Angst, J.,
Lieb, R.,
Kasper, S.
Primary anxiety disorders and the development of subsequent alcohol use disorders: a 4-year community study of adolescents and young adults (2003)
Zimmermann, P.,
Wittchen, H. U.,
Höfler, M.,
Pfister, H.,
Kessler, R. C.,
Lieb, R.
Estimating the prevalence of mental and somatic disorders in the community: aims and methods of the German National Health Interview and Examination Survey (2002)
Sommer, S,
Wittchen, HU,
Holting, C,
Jacobi, F,
Lieb, R,
Höfler, M,
...
This paper outlines the principal aims and design of the German National Health Interview and Examination Survey, mental health supplement (GHS-MHS), the first nationwide, epidemiological study of...
Patterns of incidence and psychiatric risk factors for traumatic events (2002)
Stein, MB,
Höfler, M,
Perkonigg, A,
Lieb, R,
Pfister, H,
Maercker, A,
...
Individual differences are thought to influence the propensity for exposure to trauma and the subsequent development of post- traumatic stress disorder (PTSD) symptoms. Prior research has identified...
The natural course of DSM-IV somatoform disorders and syndromes among adolescents and young adults: a prospective-longitudinal community study (2002)
Lieb, R,
Zimmermann, P,
Friis, RH,
Höfler, M,
Tholen, S,
Wittchen, HU
Objective. Although somatoform disorders are assumed to be chronic clinical conditions, epidemiological knowledge on their natural course based on representative samples is not available. Method....
Life events and changes in the course of depression in young adults (2002)
Friis, RH,
Wittchen, HU,
Pfister, H,
Lieb, R
Background. Few community-based studies have examined the impact of life events, life conditions and life changes on the course of depression. This paper oxamines associations of life events on...
Mental disorders in ecstasy users: a prospective-longitudinal investigation (2002)
Lieb, R,
Schuetz, CG,
Pfister, H,
Von Sydow, K,
Wittchen, HU
Objectives: To investigate the relationship between ecstasy use and mental disorders in a representative sample of adolescents and young adults. Method. Data for this investigation were drawn from...
What predicts incident use of cannabis and progression to abuse and dependence? A 4-year prospective examination of risk factors in a community sample of adolescents and young adults (2002)
Sydow, K Von,
Lieb, R,
Pfister, H,
Höfler, M,
Wittchen, HU
Objectives: To determine risk factors of incident onset of use, abuse and dependence of cannabis in a community sample of adolescents and young adults. Methods: Risk factors were examined in a...
Parental depression and depression in offspring: evidence for familial characteristics and subtypes? (2002)
Lieb, R,
Isensee, B,
Höfler, M,
Wittchen, HU
The objectives of this paper were twofold. First, to evaluate in a community sample the age of onset of major depression in adolescents and young adults with and without parental major depression....
Mood and anxiety disorders in patients with restless legs syndrome (2002)
Winkelmann, J,
Prager, M,
Lieb, R,
Pfister, H,
Spiegel, B,
Wittchen, HU,
...
Use, abuse and dependence of ecstasy and related drugs in adolescents and young adults - a transient phenomenon? Results from a longitudinal community study (2002)
Sydow, K Von,
Lieb, R,
Pfister, H,
Höfler, M,
Wittchen, HU
Objective: To determine incidence and patterns of natural course of ecstasy/stimulant/hallucinogen (ESH) use and disorders as well as cohort effects in a community sample of adolescents and young...
Parental major depression and the risk of depression and other mental disorders in offspring - A prospective-longitudinal community study (2002)
Lieb, R,
Isensee, B,
Höfler, M,
Pfister, H,
Wittchen, HU
Background: This article examines associations between DSM-IV depressive disorders, their natural course, other psychopathology, and parental major depression in a community sample of adolescents and...
Parental alcohol use disorders and alcohol use and disorders in offspring: a community study (2002)
Lieb, R,
Merikangas, KR,
Höfler, M,
Pfister, H,
Isensee, B,
Wittchen, HU
Background. We examined the association between parental alcohol use disorders and patterns of alcohol consumption and DSM-IV alcohol use disorders in their offspring in a community- based sample of...
Prevalence, incidence and stability of premenstrual dysphoric disorder in the community (2002)
Wittchen, HU,
Becker, E,
Lieb, R,
Krause, P
Background. Despite an abundance of clinical research on premenstrual and menstrual symptoms. few epidemiological data provide estimates of the prevalence, incidence, co-morbidity, stability and...
Patterns of incidence and psychiatric risk factors for traumatic events (2002)
Stein, M. B.,
Höfler, M.,
Perkonigg, A.,
Lieb, R.,
Pfister, H.,
Maercker, A.,
...
The natural course of cannabis use, abuse and dependence over four years: a longitudinal community study of adolescents and young adults. (2001)
Sydow, K. V.,
Lieb, R.,
Pfister, H.,
Höfler, M.,
Sonntag, H.
Epidemiologie des Konsums, Mißbrauchs und der Abhängigkeit von legalen und illegalen Drogen bei Jugendlichen und jungen Erwachsenen: Die prospektiv-longitudinale Verlaufsstudie EDSP. (2000)
Lieb, R.,
Schuster, P.,
Pfister, H.,
Fuetsch, M.,
Höfler, M.,
Isensee, B.,
...
Parental psychopathology, parenting styles, and the risk of social phobia in offspring. A prospective-longitudinal community study. (2000)
Lieb, R.,
Höfler, M.,
Fuetsch, M.,
Stein, M. B.,
Merikangas, K. R.
Patterns of cannabis use, abuse and dependence over time: incidence, progression and stability in a sample of 1228 adolescents. (1999)
Perkonigg, A.,
Lieb, R.,
Höfler, M.,
Schuster, P.,
Sonntag, H.
Vulnerability and protective factors in early developmental stages of substance use disorders. (1998)
Lieb, R.,
Schuster, P.,
Pfister, H.,
Wunderlich, U.,
Holly, A.,
Mastaler, M.,
...