Monoclonal Antibody MG96 Completely Blocks Plasmodium yoelii Development in Anopheles stephensi
Dinglasan, Rhoel R., Fields, Iesha, Shahabuddin, Mohammed, Azad, Abdu F., Sacci, John B.
In spite of research efforts to develop vaccines against the causative agent of human malaria, Plasmodium falciparum, effective control remains elusive. The predominant vaccine strategy focuses on...
Monoclonal Antibody MG96 Completely Blocks Plasmodium yoelii Development in Anopheles stephensi
Dinglasan, Rhoel R., Fields, Iesha, Shahabuddin, Mohammed, Azad, Abdu F., Sacci, John B.
In spite of research efforts to develop vaccines against the causative agent of human malaria, Plasmodium falciparum, effective control remains elusive. The predominant vaccine strategy focuses on...
Dinglasan, Rhoel R., Kalume, Dario E., Kanzok, Stefan M., Ghosh, Anil K., Muratova, Olga, Pandey, Akhilesh, ...
Malaria parasites must undergo development within mosquitoes to be transmitted to a new host. Antivector transmission-blocking vaccines inhibit parasite development by preventing ookinete interaction...
Dinglasan, Rhoel R., Alaganan, Aditi, Ghosh, Anil K., Saito, Akio, Van Kuppevelt, Toin H., Jacobs-Lorena, Marcelo
Malaria transmission entails development of the Plasmodium parasite in its insect vector, the Anopheles mosquito. Parasite invasion of the mosquito midgut is the critical first step and involves...
The Glutathione Biosynthetic Pathway of Plasmodium Is Essential for Mosquito Transmission
Vega-Rodríguez, Joel, Franke-Fayard, Blandine, Dinglasan, Rhoel R., Janse, Chris J., Pastrana-Mena, Rebecca, Waters, Andrew P., ...
Infection of red blood cells (RBC) subjects the malaria parasite to oxidative stress. Therefore, efficient antioxidant and redox systems are required to prevent damage by reactive oxygen species....