Ricardo F. Medina

The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif (2008)

Medina, Ricardo F., Buck, Timothy F., Zaidi, Sayyed K., Miele, Angela, Lian, Jane B., Stein, Janet L., ...

Accumulation of histone proteins is necessary for packaging of replicated DNA during the S phase of the cell cycle. Different mechanisms operate to regulate histone protein levels, and induction of...

The histone gene cell cycle regulator HiNF-P is a unique zinc finger transcription factor with a novel conserved auxiliary DNA-binding motif (2008)

Medina, Ricardo F., Buck, Timothy F., Zaidi, Sayyed K., Miele, Angela, Lian, Jane B., Stein, Janet L., ...

Accumulation of histone proteins is necessary for packaging of replicated DNA during the S phase of the cell cycle. Different mechanisms operate to regulate histone protein levels, and induction of...

In situ nuclear organization of regulatory machinery (2008)

Pockwinse, Shirwin M., Zaidi, Sayyed K., Medina, Ricardo F., Bakshi, Rachit, Kota, Krishna P., Ali, Syed A., ...

Regulatory machinery for gene expression, replication, and repair are architecturally organized in nuclear microenvironments. This compartmentalization provides threshold concentrations of...

MicroRNAs 221 and 222 bypass quiescence and compromise cell survival (2008)

Medina, Ricardo F., Zaidi, Sayyed K., Liu, Chang-Gong, Stein, Janet L., Van Wijnen, Andre J., Croce, Carlo M., ...

MicroRNAs (miRNA) have tumor suppressive and oncogenic potential in human cancer, but whether and how miRNAs control cell cycle progression is not understood. To address this question, we carried out...

MicroRNAs 221 and 222 bypass quiescence and compromise cell survival (2008)

Medina, Ricardo F., Zaidi, Sayyed K., Liu, Chang-Gong, Stein, Janet L., Van Wijnen, Andre J., Croce, Carlo M., ...

MicroRNAs (miRNA) have tumor suppressive and oncogenic potential in human cancer, but whether and how miRNAs control cell cycle progression is not understood. To address this question, we carried out...

The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing (2007)

Miele, Angela, Medina, Ricardo F., Van Wijnen, Andre J., Stein, Gary S., Stein, Janet L.

HiNF-P is a recently identified histone H4 subtype specific transcriptional regulator that associates with the conserved cell cycle control element in the proximal promoter regions of histone H4...

The interactome of the histone gene regulatory factor HiNF-P suggests novel cell cycle related roles in transcriptional control and RNA processing (2007)

Miele, Angela, Medina, Ricardo F., Van Wijnen, Andre J., Stein, Gary S., Stein, Janet L.

HiNF-P is a recently identified histone H4 subtype specific transcriptional regulator that associates with the conserved cell cycle control element in the proximal promoter regions of histone H4...

HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition (2005)

Miele, Angela, Braastad, Corey D., Holmes, William F., Mitra, Partha, Medina, Ricardo F., Xie, Ronglin, ...

Genome replication in eukaryotic cells necessitates the stringent coupling of histone biosynthesis with the onset of DNA replication at the G1/S phase transition. A fundamental question is the...

Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription (2004)

Zaidi, Sayyed K., Sullivan, Andrew J., Medina, Ricardo F., Ito, Yoshiaki, Van Wijnen, Andre J., Stein, Janet L., ...

Src/Yes tyrosine kinase signaling contributes to the regulation of bone homeostasis and inhibits osteoblast activity. Here we show that the endogenous Yes-associated protein (YAP), a mediator of...

Identification of HiNF-P, a key activator of cell cycle-controlled histone H4 genes at the onset of S phase (2003)

Mitra, Partha, Xie, Ronglin, Medina, Ricardo F., Hovhannisyan, Hayk, Zaidi, Sayyed K., Wei, Yue, ...

At the G(1)/S phase cell cycle transition, multiple histone genes are expressed to ensure that newly synthesized DNA is immediately packaged as chromatin. Here we have purified and functionally...