Henriette S. Nielsen, Martin B. Oleksiewicz, Roald Forsberg, Tomasz Stadejek, Anette Bøtner, Torben Storgaard
A live attenuated porcine reproductive and respiratory syndrome (PRRS) vaccine virus has been shown to revert to virulence under field conditions. In order to identify genetic virulence determinants,...
Roald Forsberg, Martin B. Oleksiewicz, Jotun Hein, Anette Bøtner, Torben Storgaard
The disease caused by porcine reproductive and respiratory syndrome virus (PRRSV) emerged independently and almost simultaneously in Europe (1990) and North America (1987). The original reservoir of...
Tree measures and the number of segregating sites in time-structured population samples (2005)
Forsberg, Roald, Drummond, Alexei J, Hein, Jotun
Abstract Background Time-structured genetic samples are a valuable source of information in population genetics because they provide several correlated observations of the underlying evolutionary...
Divergence Time of Porcine Reproductive and Respiratory Syndrome Virus Sub-types (2005)
Porcine reproductive and respiratory syndrome virus (PRRSV) recently emerged in domestic pigs of Western Europe and North America. Although time of emergence was identical on the two continents,...
Divergence Time of Porcine Reproductive and Respiratory Syndrome Virus Subtypes (2005)
Porcine reproductive and respiratory syndrome virus (PRRSV) recently emerged in domestic pigs of Western Europe and North America. Although time of emergence was identical on the two continents,...
Divergence Time of Porcine Reproductive and Respiratory Syndrome Virus Sub-types (2005)
Porcine reproductive and respiratory syndrome virus (PRRSV) recently emerged in domestic pigs of Western Europe and North America. Although time of emergence was identical on the two continents,...
An Evolutionary Model for Protein-Coding Regions with Conserved RNA Structure (2004)
Pedersen, Jakob Skou, Forsberg, Roald, Meyer, Irmtraud Margret, Hein, Jotun
Here we present a model of nucleotide substitution in protein-coding regions that also encode the formation of conserved RNA structures. In such regions, apparent evolutionary context dependencies...
Pedersen, Jakob Skou, Meyer, Irmtraud Margret, Forsberg, Roald, Simmonds, Peter, Hein, Jotun
Existing computational methods for RNA secondary-structure prediction tacitly assume RNA to only encode functional RNA structures. However, experimental studies have revealed that some RNA sequences,...
An Evolutionary Model for Protein-Coding Regions with Conserved RNA Structure (2004)
Pedersen, Jakob Skou, Forsberg, Roald, Meyer, Irmtraud Margret, Hein, Jotun
Here we present a model of nucleotide substitution in protein-coding regions that also encode the formation of conserved RNA structures. In such regions, apparent evolutionary context dependencies...
Forsberg, Roald, Christiansen, Freddy Bugge
Parasites sometimes expand their host range by acquiring a new host species. Following a host change event, the selective regime acting on a given parasite gene may change due to host-specific...
Inferring Evolutionary Rates Using Serially Sampled Sequences from Several Populations (2003)
Rodrigo, Allen G., Goode, Matthew, Forsberg, Roald, Ross, Howard A., Drummond, Alexei
The estimation of evolutionary rates from serially sampled sequences has recently been the focus of several studies. In this paper, we extend these analyses to allow the estimation of a joint rate of...
Inferring Evolutionary Rates Using Serially Sampled Sequences from Several Populations (2003)
Rodrigo, Allen G., Goode, Matthew, Forsberg, Roald, Ross, Howard A., Drummond, Alexei
The estimation of evolutionary rates from serially sampled sequences has recently been the focus of several studies. In this paper, we extend these analyzes to allow the estimation of a joint rate of...
Forsberg, Roald, Christiansen, Freddy Bugge
Parasites sometimes expand their host range by acquiring a new host species. After a host change event, the selective regime acting on a given parasite gene may change as a result of host-specific...
Forsberg, Roald, Christiansen, Freddy Bugge
Parasites sometimes expand their host range by acquiring a new host species. Following a host change event, the selective regime acting on a given parasite gene may change due to host-specific...
Inferring Evolutionary Rates Using Serially Sampled Sequences from Several Populations (2003)
Rodrigo, Allen G., Goode, Matthew, Forsberg, Roald, Ross, Howard A., Drummond, Alexei
The estimation of evolutionary rates from serially sampled sequences has recently been the focus of several studies. In this paper, we extend these analyses to allow the estimation of a joint rate of...
The Inference of Stepwise Changes in Substitution Rates Using Serial Sequence Samples (2001)
Drummond, Alexei, Forsberg, Roald, Rodrigo, Allen G.
It is frequently true that molecular sequences do not evolve in a strictly clocklike manner. Instead, substitution rate may vary for a number of reasons, including changes in selection pressure and...
A comparative method for finding and folding RNA secondary structures within protein-coding regions
Pedersen, Jakob Skou, Meyer, Irmtraud Margret, Forsberg, Roald, Simmonds, Peter, Hein, Jotun
Existing computational methods for RNA secondary-structure prediction tacitly assume RNA to only encode functional RNA structures. However, experimental studies have revealed that some RNA sequences,...
A comparative method for finding and folding RNA secondary structures within protein-coding regions
Pedersen, Jakob Skou, Meyer, Irmtraud Margret, Forsberg, Roald, Simmonds, Peter, Hein, Jotun
Existing computational methods for RNA secondary-structure prediction tacitly assume RNA to only encode functional RNA structures. However, experimental studies have revealed that some RNA sequences,...