Incorrect or Defective Pill Detection Using a Dynamic Data-Driven Application System Paradigm (2009)
Craig C. Douglas, Gundolf Haase, Thad Hannel, David Link, Robert A. Lodder
Abstract — Identification of defective tablets at the time of creation is currently infeasible. Medications are dispensed to patients in health care locations without a final check to see if a...
L. F. Perrone, F. P. Wiel, J. Liu, B. G. Lawson, D. M. Nicol, R. M. Fujimoto, ...
We report on two ongoing efforts to build Dynamic Data
Thaddaeus Hannel, David Link, Robert A. Lodder
manufacturing Integrated sensing and processing acoustic resonance spectroscopy (ISP-ARS) is a novel approach to acoustic spectroscopy that can be implemented using instruments as simple as an MP3...
Often the biggest problem for a SETI station is storage and analysis of data. GoidWave is a shareware program that can help reduce this problem. GoidWave is a digital audio editor for Windows...
internet column Using the Internet as an analytical instrument (2009)
Kimberly L. Glenn, Dana Rodgers, Robert A. Lodder, Cynthia L. Banyon
Analytical chemists are presented daily with a variety of real-world questions in which the chemical identi¢cation and quanti¢cation of a sample is the simplest part of the problem. In the past...
Kimberly L. Glenn, Dana Rodgers, Robert A. Lodder, Cynthia L. Banyon
Analytical chemists are presented daily with a variety of real-world questions in which the chemical identification and quantification of a sample is the simplest part of the problem. In the past...
Near- Infrared Spectrometry of Microorganisms in Liquid (2009)
Leonard J. Galante, Michael A. Brinkley, James K. Drennen, Robert A. Lodder
Biotechnology and phatmaceutkal research have created a number of new and potentlally life-saving drugs. Many of these h gs are formulated as Injectable proclucts. Some drug products do not wive...
Applications of integrated sensing and processing in spectroscopic imaging and sensing (2009)
Joseph Medendorp, Robert A. Lodder
Integrated sensing and processing (ISP) encompasses the use of optical computing and adapted excitation signals to physically implement chemometric calculations in spectroscopic sensors for imaging....
Leonard Galante, Michael A. Brinkley, Robert A. Lodder
Aseptic-filling processes are often used with frnile parenteral prod-12CR that might be destroyed by terminal autoclaving. However. aseptic filling is not as effective as autoclaving in reducing...
Implantable Sensor Batteries Prospects for implantable sensors powered (2009)
Bin Dai Aaron Urbas, Robert A. Lodder
Many useful computing, networking and sensing devices could be implanted inside the body if they could only be reliably powered. At the University of Kentucky, our group is looking at spectrometric...
21 CFR 211.110(a)(3). Considering also, the U.S. Food and Drug Administration's draft (2009)
Arwa S. El-hagrasy, Hannah R. Morris, Robert A. Lodder, James K. Drennen Iii
ABSTRACT: In-process testing requirements for adequacy of mixing are established in
*Author to whom correspondence should be addressed. (2009)
Joseph P. Medendorp, Jason A. Fackler, Craig C. Douglas, Robert A. Lodder
discriminant analysis, This research introduces a novel process analytical technique, integrated sensing and processing acoustic resonance spectrometry (ISP-ARS), and compares ISP-ARS with...
Hyperspectral imaging technology for pharmaceutical analysis (2009)
Sara J. Hamilton, Robert A. Lodder
The sensitivity and spatial resolution of hyperspectral imaging instruments are tested in this paper using pharmaceutical applications. The first experiment tested the hypothesis that a near-IR...
Joseph Medendorp, Joseph Wyse, Robert A. Lodder, Lloyd G. Tillman, Ujatha Sonti, Isis Pharmaceuticals
In this study we show the application of a nondestructive process analytical technology to separate two populations of enteric coated capsules that contained minitablets. In the course of a small,...
Robert G. Bhice, Thomas B. Gold, Robert A. Lodder, George A. Digenis
spect rophotomet ry. INTRODI:CI ION Pharmaceutical application of near-infrared spectrophotometry offers rapid, nondestructive, and noninvasive techniques to analyze samples. the analytical power of...
Robert A. Lodder, Mark Selby, Gary M. Hieftje
240 trends in analytical chemistry, vol. 7, no. 7, 1988
Near-Infrared (IR) Spectronietric Imaging Using a One-Meter Fresnel Telescope (2008)
Robert A. Lodder, Cynthia L. Banyon, Email Lodderpop. Uky. Edu
A near-infrared optical telescope with an aperture of approximately one-meter has been constructed to detect interstellar laser transmissions. The near-JR telescope (4760 to 25000 cm') is being...
Craig C. Douglas Divya Bansal, Janice L. Coen, Yalchin Efendiev, Richard E. Ewing, Jay Hatcher, Mohamed Isk, ...
We quote from the 2005 dynamic data-driven application systems (DDDAS) National Science Foundation solicitation [9], “DDDAS is a paradigm whereby application (or simulations) and measurements...
PROOF COPY 005204JBO Journal of Biomedical Optics 7(4), 1–0 (October 2002) (2008)
Hyperspectral Techniques In, Sara J. Hamilton, Amanda E. Lowell, Robert A. Lodder
Pharmaceutical oral dosage forms are used in this paper to test the sensitivity and spatial resolution of hyperspectral imaging instruments. The first experiment tested the hypothesis that a...
RESEARCH ARTICLE Integrated Sensing and Processing Acoustic Resonance (2007)
Joseph P. Medendorp, Jason A. Fackler, Craig C. Douglas, Robert A. Lodder, C. C. Douglas
Abstract This research introduces a novel process analytical technique, integrated sensing and processing acoustic resonance spectrometry (ISP-ARS), and compares ISP-ARS with conventional...
Joseph P. Medendorp, Kalpana S. Paudel, Robert A. Lodder, Audra L. Stinchcomb
Purpose. The purpose of this study was to demonstrate the use of near-infrared (NIR) spectrometry for the in vitro quantification of econazole nitrate (EN) and estradiol (EST) in human skin. Methods....
Molecular Factor Computing for Predictive Spectroscopy (2006)
Bin Dai, Aaron Urbas, Craig C. Douglas, Robert A. Lodder
Purpose. The concept of molecular factor computing (MFC)-based predictive spectroscopy was demonstrated here with quantitative analysis of ethanol-in-water mixtures in a MFC-based prototype...
Joseph Medendorp, Jhansi Yedluri, Dana C. Hammell, Tao Ji, Robert A. Lodder, Audra L. Stinchcomb
Purpose. The purpose of this study was to demonstrate the utility of near-infrared (NIR) spectroscopy for the in vitro quantification of econazole nitrate (EN) and 4-cyanophenol (4-CP) in hairless...
Detection of Capsule Tampering by Near-Infrared Reflectance Analysis. (1998)
Lodder,Robert A., Selby,Mark, Hieftje,Gary M.
The growing incidence of product tampering has brought to attention the need for a rapid, reliable, inexpensive, noninvasive and nondestructive method of screening. Such a method, based on...
A Disposable Liquid Microcell for Near-Infrared Reflectance Analysis. (1998)
Lodder, Robert A., Hieftje, Gary M.
A disposable, 70 microliter, liquid analysis transmission cell is described for use in near infrared reflectance instruments. The small sample volume relative to the overall cell size allows many...
Detection of Subpopulations in Near-Infrared Reflectance Analysis. (1998)
Lodder, Robert A., Hieftje, Gary M.
In typical near-infrared multivariate statistical analyses, samples with similar spectra produce points that cluster in a certain region of spectral hyperspace. These clusters can vary significantly...
Applications of Cellular Automata: Attractors and Fractals in Analytical Chemistry. (1998)
Lodder, Robert A., Selby, Mark, Hieftje, Gary M.
A cellular automation is a discrete dynamic system of simple construction, yet capable of exhibiting complex self-organizing behavior. A cellular automaton can be used to model differential systems...
Lodder, Robert A., Hieftje, Gary M.
The multiple linear regression approach typically used in near-infrared calibration yields equations in which any amount of reflectance at the analytical wavelengths leads to a corresponding...
Quantile Analysis: A Method for Characterizing Data Distributions. (1998)
Lodder, Robert A., Hieftje, Gary M.
Analyzing distributions of data represents a common problem in analytical chemistry. Quantile-quantile (QQ) plots provide a useful way to attack this problem. These graphs are often used in the form...
Thesis (M.S.)--Xavier University, 1983.
Craig C. Douglas, Divya Bansal, Jonathan D. Beezley, Soham Chakraborty, Janice L. Coen, Yalchin Efendiev, ...
We describe three different dynamic data-driven applications systems (DDDAS): an empty house, a contaminant identification and tracking, and a wildland fire. Each has something in common with all of...